Published in J Clin Microbiol on September 01, 1994
Improved reactivity of hepatitis C virus core protein epitopes in a conformational antigen-presenting system. Clin Diagn Lab Immunol (1997) 0.79
Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome. Science (1989) 37.89
An assay for circulating antibodies to a major etiologic virus of human non-A, non-B hepatitis. Science (1989) 18.79
Vectors for selective expression of cloned DNAs by T7 RNA polymerase. Gene (1987) 17.98
Use of bacteriophage T7 lysozyme to improve an inducible T7 expression system. J Mol Biol (1991) 5.81
Full-length sequence of a hepatitis C virus genome having poor homology to reported isolates: comparative study of four distinct genotypes. Virology (1992) 5.16
Detection of hepatitis C virus RNA by a combined reverse transcription-polymerase chain reaction assay. J Clin Microbiol (1993) 3.34
The Taiwanese hepatitis C virus genome: sequence determination and mapping the 5' termini of viral genomic and antigenomic RNA. Virology (1992) 2.88
Hepatitis B virus core antigen: synthesis in Escherichia coli and application in diagnosis. Proc Natl Acad Sci U S A (1982) 2.19
Diagnosis of hepatitis C virus (HCV) infection using an immunodominant chimeric polyprotein to capture circulating antibodies: reevaluation of the role of HCV in liver disease. Proc Natl Acad Sci U S A (1992) 2.18
Improved serodiagnosis of hepatitis C virus infection with synthetic peptide antigen from capsid protein. Proc Natl Acad Sci U S A (1991) 1.81
Demonstration of viraemia patterns in haemophiliacs treated with hepatitis-C-virus-contaminated factor VIII concentrates. Lancet (1990) 1.69
Use of aminotransferase, hepatitis C antibody, and hepatitis C polymerase chain reaction RNA assays to establish the diagnosis of hepatitis C virus infection in a diagnostic virology laboratory. J Clin Microbiol (1992) 1.59
Long-term follow-up of non-A, non-B (type C) post-transfusion hepatitis. J Hepatol (1992) 1.50
Serodiagnosis of hepatitis C virus (HCV) infection with an HCV core protein molecularly expressed by a recombinant baculovirus. Proc Natl Acad Sci U S A (1991) 1.36
Detection of hepatitis C virus antibody in the absence of viral RNA in patients with autoimmune hepatitis. Ann Intern Med (1992) 1.31
Three different patterns of hepatitis C virus infection in chimpanzees. Hepatology (1992) 1.21
Detection of hepatitis C virus sequences in sera with controversial serology by nested polymerase chain reaction. J Clin Microbiol (1992) 1.09
Early antihepatitis C virus response with second-generation C200/C22 ELISA. Vox Sang (1992) 1.08
Polymerase chain reaction assay for hepatitis C virus RNA using a single tube for reverse transcription and serial rounds of amplification with nested primer pairs. J Med Virol (1992) 1.03
Enhanced sensitivity of a second generation ELISA for antibody to hepatitis C virus. Vox Sang (1992) 0.96
Transient immunoglobulin M antibody response to hepatitis C virus capsid antigen in posttransfusion hepatitis C: putative serological marker for acute viral infection. Proc Natl Acad Sci U S A (1992) 0.93
Hepatitis C virus in blood samples from volunteer donors. J Clin Microbiol (1993) 0.93
Detection of antibodies to hepatitis C virus (HCV) structural proteins in anti-HCV-positive sera by an enzyme-linked immunosorbent assay using synthetic peptides as antigens. J Clin Microbiol (1993) 0.93
Acute hepatitis C virus superinfection followed by spontaneous HBeAg seroconversion and HBsAg elimination. Infection (1991) 0.88
Serological response and detection of viraemia in acute hepatitis C virus infection. J Hepatol (1992) 0.88
Correlation of serum antibody titers against hepatitis C virus core protein with clinical features by western blot (immunoblot) analysis using a recombinant vaccinia virus expression system. J Clin Microbiol (1993) 0.87
Non-A, non-B hepatitis. Virchows Arch A Pathol Anat Histopathol (1989) 0.85
Improved serodiagnosis of non-A, non-B hepatitis by an assay detecting antibody to hepatitis C virus core antigen. Hepatology (1992) 0.84
Association of hepatitis C virus carrier state with the occurrence of hepatitis C virus core antibodies. J Med Virol (1992) 0.83
Serodiagnosis of hepatitis C virus infection by ELISA for antibodies against the putative core protein (p20c) expressed in Escherichia coli. J Immunol Methods (1992) 0.79
Excretion of caffeine and its primary degradation products into bile. J Hepatol (1993) 0.77
Expression of hepatitis C virus core protein as a fusion protein with maltose binding protein. Detection of anti-hepatitis C core antibody by western blot. Dig Dis Sci (1993) 0.77
Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study. Lancet (2003) 13.79
The human insulin receptor cDNA: the structural basis for hormone-activated transmembrane signalling. Cell (1985) 7.45
Structure, sequence and expression of the hepatitis delta (delta) viral genome. Nature (1986) 7.38
Hepatitis B virus gene function: the precore region targets the core antigen to cellular membranes and causes the secretion of the e antigen. Proc Natl Acad Sci U S A (1986) 4.73
Acute exacerbation and hepatitis B virus clearance after emergence of YMDD motif mutation during lamivudine therapy. Hepatology (1999) 3.11
A signal peptide encoded within the precore region of hepatitis B virus directs the secretion of a heterogeneous population of e antigens in Xenopus oocytes. Proc Natl Acad Sci U S A (1988) 2.84
Trans-activation of the human immunodeficiency virus long terminal repeat by the hepatitis B virus X protein. Proc Natl Acad Sci U S A (1988) 2.79
Sequence studies of several alphavirus genomic RNAs in the region containing the start of the subgenomic RNA. Proc Natl Acad Sci U S A (1982) 2.77
The development of cirrhosis in patients with chronic type B hepatitis: a prospective study. Hepatology (1988) 2.75
Effects of a naturally occurring mutation in the hepatitis B virus basal core promoter on precore gene expression and viral replication. J Virol (1996) 2.68
Epidemiological characteristics and risk factors of hepatocellular carcinoma. J Gastroenterol Hepatol (1997) 2.66
Targeting of the hepatitis B virus precore protein to the endoplasmic reticulum membrane: after signal peptide cleavage translocation can be aborted and the product released into the cytoplasm. J Cell Biol (1988) 2.41
Assembly of viral particles in Xenopus oocytes: pre-surface-antigens regulate secretion of the hepatitis B viral surface envelope particle. Proc Natl Acad Sci U S A (1986) 2.28
Familial risk of hepatocellular carcinoma among chronic hepatitis B carriers and their relatives. J Natl Cancer Inst (2000) 2.23
Long-term beneficial effect of interferon therapy in patients with chronic hepatitis B virus infection. Hepatology (1999) 2.16
Eosinophilic gastroenteritis: 10 years experience. Am J Gastroenterol (1993) 2.15
Comparative studies of the 3'-terminal sequences of several alpha virus RNAs. Virology (1981) 2.15
Hormonal markers and hepatitis B virus-related hepatocellular carcinoma risk: a nested case-control study among men. J Natl Cancer Inst (2001) 2.11
Detection of type 2-like T-helper cells in hepatitis C virus infection: implications for hepatitis C virus chronicity. Hepatology (1997) 2.06
The 5'-terminal sequences of the genomic RNAs of several alphaviruses. J Mol Biol (1983) 2.05
Intrahepatic distribution of hepatitis B surface and core antigens in chronic hepatitis B virus infection. Hepatocyte with cytoplasmic/membranous hepatitis B core antigen as a possible target for immune hepatocytolysis. Gastroenterology (1987) 2.02
Identity of a novel swine hepatitis E virus in Taiwan forming a monophyletic group with Taiwan isolates of human hepatitis E virus. J Clin Microbiol (1999) 1.99
Activation of nuclear factor kappaB in hepatitis C virus infection: implications for pathogenesis and hepatocarcinogenesis. Hepatology (2000) 1.96
The 3'-non-coding regions of alphavirus RNAs contain repeating sequences. J Mol Biol (1982) 1.92
Hepatic arterial embolization in patients with unresectable hepatocellular carcinoma--a randomized controlled trial. Gastroenterology (1988) 1.91
Liver biochemical tests and dengue fever. Am J Trop Med Hyg (1992) 1.89
Early detection of hepatocellular carcinoma in patients with chronic type B hepatitis. A prospective study. Gastroenterology (1986) 1.84
Hepatitis C virus core protein interacts with the cytoplasmic tail of lymphotoxin-beta receptor. J Virol (1997) 1.84
Prospective study of hepatocellular carcinoma and liver cirrhosis in asymptomatic chronic hepatitis B virus carriers. Am J Epidemiol (1997) 1.83
The arginine-rich domain of hepatitis B virus precore and core proteins contains a signal for nuclear transport. J Virol (1990) 1.79
Effects of hepatitis B virus, alcohol drinking, cigarette smoking and familial tendency on hepatocellular carcinoma. Hepatology (1991) 1.78
Subcellular localization of hepatitis B core antigen in relation to hepatocyte regeneration in chronic hepatitis B. Gastroenterology (1995) 1.75
Differential subcellular localization of hepatitis C virus core gene products. Virology (1995) 1.73
Is the p53 gene mutation of prognostic value in hepatocellular carcinoma after resection? Arch Surg (2000) 1.68
Phosphorylation and nuclear localization of the hepatitis B virus core protein: significance of serine in the three repeated SPRRR motifs. J Virol (1995) 1.66
Non-surgical treatment of hepatocellular carcinoma. J Gastroenterol Hepatol (1997) 1.66
Regulation of secretion of the hepatitis B virus major surface antigen by the preS-1 protein. J Virol (1987) 1.64
Genome-wide hypomethylation in hepatocellular carcinogenesis. Cancer Res (2001) 1.64
Characterization of nuclear targeting signal of hepatitis delta antigen: nuclear transport as a protein complex. J Virol (1992) 1.63
Clearance of the original hepatitis B virus YMDD-motif mutants with emergence of distinct lamivudine-resistant mutants during prolonged lamivudine therapy. Hepatology (2000) 1.62
Prednisolone priming enhances Th1 response and efficacy of subsequent lamivudine therapy in patients with chronic hepatitis B. Hepatology (2000) 1.62
Fulminant hepatic failure in acute hepatitis C: increased risk in chronic carriers of hepatitis B virus. Gut (1999) 1.60
Sequence analysis of cDNA's derived from the RNA of Sindbis virions and of defective interfering particles. J Virol (1982) 1.59
Viral loads in clinical specimens and SARS manifestations. Emerg Infect Dis (2004) 1.55
Cell cycle regulation of nuclear localization of hepatitis B virus core protein. Proc Natl Acad Sci U S A (1993) 1.55
Hepatic injury during ketoconazole therapy in patients with onychomycosis: a controlled cohort study. Hepatology (1997) 1.54
Hepatocyte-specific expression of the hepatitis B virus core promoter depends on both positive and negative regulation. Mol Cell Biol (1993) 1.50
Hepatitis C virus variants circumventing cytotoxic T lymphocyte activity as a mechanism of chronicity. Gastroenterology (1998) 1.47
Mechanism of suppression of hepatitis B virus precore RNA transcription by a frequent double mutation. J Virol (1999) 1.46
Natural history of chronic hepatitis B virus infection in Taiwan: studies of hepatitis B virus DNA in serum. Hepatology (1985) 1.45
Role of hepatitis C and delta viruses in the termination of chronic hepatitis B surface antigen carrier state: a multivariate analysis in a longitudinal follow-up study. J Infect Dis (1994) 1.44
Clinical and histological events preceding hepatitis B e antigen seroconversion in chronic type B hepatitis. Gastroenterology (1983) 1.44
Constitutive activation of nuclear factor kappaB in hepatocellular carcinoma. Cancer (2000) 1.39
Interaction between hepatitis C virus core protein and E1 envelope protein. J Virol (1996) 1.39
A p53 genetic polymorphism as a modulator of hepatocellular carcinoma risk in relation to chronic liver disease, familial tendency, and cigarette smoking in hepatitis B carriers. Hepatology (1999) 1.38
Activation of class I major histocompatibility complex gene expression by hepatitis B virus. J Virol (1990) 1.37
Incidence, determinants and significance of delayed clearance of serum HBsAg in chronic hepatitis B virus infection: a prospective study. Hepatology (1991) 1.35
A case-control study of primary hepatocellular carcinoma in Taiwan. Cancer (1988) 1.35
Identification of a novel strain of hepatitis E virus responsible for sporadic acute hepatitis in Taiwan. J Med Virol (1998) 1.34
Improvement in diabetes control with a monitoring system based on a hand-held, touch-screen electronic diary. J Telemed Telecare (2001) 1.34
Pretherapy alanine transaminase level as a determinant for hepatitis B e antigen seroconversion during lamivudine therapy in patients with chronic hepatitis B. Asian Hepatitis Lamivudine Trial Group. Hepatology (1999) 1.32
Characterization of the hepatitis B virus EnhI enhancer and X promoter complex. J Virol (1991) 1.27
Ultrasonographic changes of early liver cirrhosis in chronic hepatitis B: a longitudinal study. J Clin Ultrasound (1993) 1.26
First EBV vaccine trial in humans using recombinant vaccinia virus expressing the major membrane antigen. Dev Biol Stand (1995) 1.25
Metastatic septic endophthalmitis in pyogenic liver abscess. J Clin Gastroenterol (1988) 1.25
Androgen-receptor gene CAG repeats, plasma testosterone levels, and risk of hepatitis B-related hepatocellular carcinoma. J Natl Cancer Inst (2000) 1.22
Phosphorylation of hepatitis B virus precore and core proteins. J Virol (1991) 1.21
Hepatic decompensation associated with hepatitis B e antigen clearance in chronic type B hepatitis. Gastroenterology (1985) 1.21
Comparative studies of the core gene products of two different hepatitis C virus isolates: two alternative forms determined by a single amino acid substitution. Virology (1994) 1.21
Non-O1 Vibrio cholerae bacteremia in patients with cirrhosis: 5-yr experience from a single medical center. Am J Gastroenterol (1996) 1.21
Bacteremia in patients with cirrhosis of the liver. Liver (1991) 1.20
Purification and characterization of a naturally processed hepatitis B virus peptide recognized by CD8+ cytotoxic T lymphocytes. J Clin Invest (1996) 1.20
Hepatic injury during propylthiouracil therapy in patients with hyperthyroidism. A cohort study. Ann Intern Med (1993) 1.19
Hepatitis B viral DNA in infected human liver and in hepatocellular carcinoma. J Infect Dis (1985) 1.18
Hepatic tuberculosis: comparison of miliary and local form. Infection (1995) 1.18
Association between hepatitis C virus antibodies and hepatocellular carcinoma in Taiwan. Cancer Res (1991) 1.18