Published in Biochemistry on October 10, 1995
Coupled ion movement underlies rectification in an inward-rectifier K+ channel. J Gen Physiol (1998) 1.94
mu-conotoxin GIIIA interactions with the voltage-gated Na(+) channel predict a clockwise arrangement of the domains. J Gen Physiol (2000) 1.30
The role of a single aspartate residue in ionic selectivity and block of a murine inward rectifier K+ channel Kir2.1. J Physiol (1996) 1.15
The role of the cytoplasmic pore in inward rectification of Kir2.1 channels. J Gen Physiol (2007) 0.99
Hydrophobic mutations alter the movement of Mg2+ in the pore of voltage-gated potassium channels. Biophys J (1996) 0.94
Extracellular protons titrate voltage gating of a ligand-gated ion channel. J Gen Physiol (2010) 0.78
Characterization and functional restoration of a potassium channel Kir6.2 pore mutation identified in congenital hyperinsulinism. J Biol Chem (2009) 0.78
The structure of the potassium channel: molecular basis of K+ conduction and selectivity. Science (1998) 39.86
Chemistry of ion coordination and hydration revealed by a K+ channel-Fab complex at 2.0 A resolution. Nature (2001) 13.76
Contribution of the S4 segment to gating charge in the Shaker K+ channel. Neuron (1996) 8.11
Crystal structures of a complexed and peptide-free membrane protein-binding domain: molecular basis of peptide recognition by PDZ. Cell (1996) 6.87
Mutations in the K+ channel signature sequence. Biophys J (1994) 6.81
Energetic optimization of ion conduction rate by the K+ selectivity filter. Nature (2001) 5.45
Potassium channel receptor site for the inactivation gate and quaternary amine inhibitors. Nature (2001) 5.44
Mutations affecting internal TEA blockade identify the probable pore-forming region of a K+ channel. Science (1991) 5.42
The aromatic binding site for tetraethylammonium ion on potassium channels. Neuron (1992) 4.91
Gating currents from a nonconducting mutant reveal open-closed conformations in Shaker K+ channels. Neuron (1993) 4.55
A functional connection between the pores of distantly related ion channels as revealed by mutant K+ channels. Science (1992) 3.98
Abnormal intracellular calcium handling in myocardium from patients with end-stage heart failure. Circ Res (1987) 3.86
Revealing the architecture of a K+ channel pore through mutant cycles with a peptide inhibitor. Science (1995) 3.82
Electrostatic tuning of Mg2+ affinity in an inward-rectifier K+ channel. Nature (1994) 3.75
The cavity and pore helices in the KcsA K+ channel: electrostatic stabilization of monovalent cations. Science (1999) 3.66
Structure of the RCK domain from the E. coli K+ channel and demonstration of its presence in the human BK channel. Neuron (2001) 3.62
Charybdotoxin block of single Ca2+-activated K+ channels. Effects of channel gating, voltage, and ionic strength. J Gen Physiol (1988) 2.87
Hanatoxin modifies the gating of a voltage-dependent K+ channel through multiple binding sites. Neuron (1997) 2.62
Conduction properties of the cloned Shaker K+ channel. Biophys J (1993) 2.56
The barium site in a potassium channel by x-ray crystallography. J Gen Physiol (2000) 2.44
Two identical noninteracting sites in an ion channel revealed by proton transfer. Science (1994) 2.44
Spatial localization of the K+ channel selectivity filter by mutant cycle-based structure analysis. Neuron (1996) 2.38
Mapping the receptor site for hanatoxin, a gating modifier of voltage-dependent K+ channels. Neuron (1997) 2.35
Identification of an external divalent cation-binding site in the pore of a cGMP-activated channel. Neuron (1993) 2.33
Structure of the cytoplasmic beta subunit-T1 assembly of voltage-dependent K+ channels. Science (2000) 2.29
An inhibitor of the Kv2.1 potassium channel isolated from the venom of a Chilean tarantula. Neuron (1995) 2.06
Agitoxin footprinting the shaker potassium channel pore. Neuron (1996) 1.99
Purification and characterization of three inhibitors of voltage-dependent K+ channels from Leiurus quinquestriatus var. hebraeus venom. Biochemistry (1994) 1.97
Structure of a voltage-dependent K+ channel beta subunit. Cell (1999) 1.64
Transfer of the scorpion toxin receptor to an insensitive potassium channel. Neuron (1994) 1.50
A simple model for multi-ion permeation. Single-vacancy conduction in a simple pore model. Biophys J (1990) 1.27
Ion channels: from idea to reality. Nat Med (1999) 1.20
Influence of protein surface charge on the bimolecular kinetics of a potassium channel peptide inhibitor. Biochemistry (1993) 1.16
Divalent cation selectivity in a cyclic nucleotide-gated ion channel. Biochemistry (1995) 1.16
A conductance maximum observed in an inward-rectifier potassium channel. J Gen Physiol (1994) 1.16
Isolation of a single carboxyl-carboxylate proton binding site in the pore of a cyclic nucleotide-gated channel. J Gen Physiol (1999) 1.12
A snake toxin inhibitor of inward rectifier potassium channel ROMK1. Biochemistry (1998) 1.11
Energetic and structural interactions between delta-dendrotoxin and a voltage-gated potassium channel. J Mol Biol (2000) 1.10
Assessing the subjective experience of being a participant in psychiatric research. Am J Psychiatry (2001) 1.03
Purification, characterization, and synthesis of an inward-rectifier K+ channel inhibitor from scorpion venom. Biochemistry (1997) 1.00
Solution structure of the potassium channel inhibitor agitoxin 2: caliper for probing channel geometry. Protein Sci (1995) 0.99
Prokaryotes offer hope for potassium channel structural studies. Nat Struct Biol (1997) 0.92
Differential effects of reoxygenation on intracellular calcium and isometric tension. Pflugers Arch (1987) 0.90
Influence of the thyroid state on the calcium transient in ventricular muscle. Pflugers Arch (1986) 0.80
Purification of human alpha uterine protein. J Reprod Fertil (1980) 0.78
Should premedication be used for semi-urgent or elective intubation in neonates? Arch Dis Child (2006) 0.77
Low-flow anaesthesia in paediatric patients. Br J Anaesth (2011) 0.75
Evaluation of human microdissection clones from the FRAXA region as tools for comparative mapping in the mouse: isolation of a conserved genomic clone close to FMR1. Mamm Genome (1994) 0.75
Psychiatric care through home nursing services. Curr Psychiatr Ther (1969) 0.75
The cosmid CSSM25 assigns syntenic group U2 to bovine chromosome 9 and is localized to ovine chromosome 8. Mamm Genome (1995) 0.75
A clinical clerkship in psychiatry. J Med Educ (1975) 0.75