Published in J Pharmacol Exp Ther on October 01, 1995
Quantitative high performance liquid chromatography/tandem mass spectrometric analysis of the four classes of F(2)-isoprostanes in human urine. Proc Natl Acad Sci U S A (1999) 1.45
IPF2alpha-I: an index of lipid peroxidation in humans. Proc Natl Acad Sci U S A (1998) 1.43
Localization of distinct F2-isoprostanes in human atherosclerotic lesions. J Clin Invest (1997) 1.38
Oxidative stress and enhanced sympathetic vasoconstriction in contracting muscles of nitrate-tolerant rats and humans. J Physiol (2011) 1.10
Exhaled 8-isoprostane as a new non-invasive biomarker of oxidative stress in cystic fibrosis. Thorax (2000) 1.08
F2-isoprostanes as an indicator and risk factor for coronary heart disease. Free Radic Biol Med (2010) 1.04
Oxidative damage, platelet activation, and inflammation to predict mobility disability and mortality in older persons: results from the health aging and body composition study. J Gerontol A Biol Sci Med Sci (2012) 1.00
Oxidative stress mediated arterial dysfunction in patients with obstructive sleep apnoea and the effect of continuous positive airway pressure treatment. BMC Pulm Med (2012) 0.99
Oestrogen metabolites in relation to isoprostanes as a measure of oxidative stress. Clin Endocrinol (Oxf) (2007) 0.99
Oxidative stress in the aging rat heart is reversed by dietary supplementation with (R)-(alpha)-lipoic acid. FASEB J (2001) 0.99
Measurement of isoprostanes as markers of oxidative stress in neuronal tissue. Curr Protoc Toxicol (2009) 0.97
Urinary 15-F2t-isoprostane, aflatoxin B1 exposure and hepatitis B virus infection and hepatocellular carcinoma in Taiwan. Carcinogenesis (2008) 0.93
Lower bone mineral density in children with type 1 diabetes is associated with poor glycemic control and higher serum ICAM-1 and urinary isoprostane levels. J Bone Miner Metab (2009) 0.93
Effect of α-lipoic acid on platelet reactivity in type 1 diabetic patients. Diabetes Care (2012) 0.89
Induction of prostaglandin endoperoxide synthase-2 in human monocytes associated with cyclo-oxygenase-dependent F2-isoprostane formation. Br J Pharmacol (1996) 0.88
Dietary fat subgroups, zinc, and vegetable components are related to urine F2a-isoprostane concentration, a measure of oxidative stress, in midlife women. J Nutr (2007) 0.88
Oxidative lipidomics coming of age: advances in analysis of oxidized phospholipids in physiology and pathology. Antioxid Redox Signal (2015) 0.88
Rapid quantitative analysis of 8-iso-prostaglandin-F(2alpha) using liquid chromatography-tandem mass spectrometry and comparison with an enzyme immunoassay method. Anal Biochem (2010) 0.86
Synthesis of 8-epi-prostaglandin F2alpha by human endothelial cells: role of prostaglandin H2 synthase. Biochem J (1999) 0.85
NOX2-generated oxidative stress is associated with severity of ultrasound liver steatosis in patients with non-alcoholic fatty liver disease. BMC Gastroenterol (2014) 0.84
Enhanced lipid peroxidation and platelet activation as potential contributors to increased cardiovascular risk in the low-HDL phenotype. J Am Heart Assoc (2013) 0.83
Lipid peroxidation and depressed mood in community-dwelling older men and women. PLoS One (2013) 0.83
Plasma Carotenoids and Biomarkers of Oxidative Stress in Patients with prior Head and Neck Cancer. Biomark Insights (2009) 0.82
Mitochondrial DNA sequence associations with dementia and amyloid-β in elderly African Americans. Neurobiol Aging (2013) 0.81
Toxicological profile of chlorophenols and their derivatives in the environment: the public health perspective. ScientificWorldJournal (2013) 0.81
Long-term vitamin E supplementation fails to reduce lipid peroxidation in people at cardiovascular risk: analysis of underlying factors. Curr Control Trials Cardiovasc Med (2002) 0.80
Circulating myeloid-related protein-8/14 is related to thromboxane-dependent platelet activation in patients with acute coronary syndrome, with and without ongoing low-dose aspirin treatment. J Am Heart Assoc (2014) 0.80
Moderate weight loss decreases oxidative stress and increases antioxidant status in patients with metabolic syndrome. ISRN Obes (2012) 0.80
Serum Cytokeratin-18 Is Associated with NOX2-Generated Oxidative Stress in Patients with Nonalcoholic Fatty Liver. Int J Hepatol (2014) 0.78
Different degrees of NADPH oxidase 2 regulation and in vivo platelet activation: lesson from chronic granulomatous disease. J Am Heart Assoc (2014) 0.77
Effect of common single nucleotide polymorphisms in COX-1 gene on related metabolic activity in diabetic patients treated with acetylsalicylic acid. Arch Med Sci (2013) 0.75
Vascular and upper gastrointestinal effects of non-steroidal anti-inflammatory drugs: meta-analyses of individual participant data from randomised trials. Lancet (2013) 8.16
The coxibs, selective inhibitors of cyclooxygenase-2. N Engl J Med (2001) 5.29
Editor's Choice - Management of Chronic Venous Disease: Clinical Practice Guidelines of the European Society for Vascular Surgery (ESVS). Eur J Vasc Endovasc Surg (2015) 4.18
Activation of human aortic smooth-muscle cells is inhibited by PPARalpha but not by PPARgamma activators. Nature (1998) 3.48
Are Frozen Foods a Public Health Problem? Am J Public Health Nations Health (1947) 3.44
Biomarkers of oxidative stress study II: are oxidation products of lipids, proteins, and DNA markers of CCl4 poisoning? Free Radic Biol Med (2005) 3.13
In vivo formation of 8-iso-prostaglandin f2alpha and platelet activation in diabetes mellitus: effects of improved metabolic control and vitamin E supplementation. Circulation (1999) 2.90
Radioimmunoassay of prostaglandins Falpha, E1 and E2 in human plasma. Eur J Clin Invest (1975) 2.80
Low dose aspirin and inhibition of thromboxane B2 production in healthy subjects. Thromb Res (1980) 2.68
Differential effects of aspirin and non-aspirin nonsteroidal antiinflammatory drugs in the primary prevention of myocardial infarction in postmenopausal women. Epidemiology (2000) 2.63
The Concise Guide to PHARMACOLOGY 2013/14: overview. Br J Pharmacol (2013) 2.48
Clinical pharmacology of platelet cyclooxygenase inhibition. Circulation (1985) 2.46
No evidence for lipid peroxidation in severe preeclampsia. Am J Obstet Gynecol (2001) 2.28
Clinical characteristics of vasodepressor, cardioinhibitory, and mixed carotid sinus syndrome in the elderly. Am J Med (1993) 2.25
Selective cumulative inhibition of platelet thromboxane production by low-dose aspirin in healthy subjects. J Clin Invest (1982) 2.23
Enzyme immunoassays of eicosanoids using acetylcholine esterase as label: an alternative to radioimmunoassay. Anal Chem (1985) 2.22
Exhaled 8-isoprostane as an in vivo biomarker of lung oxidative stress in patients with COPD and healthy smokers. Am J Respir Crit Care Med (2000) 2.03
Reference: the linguistic essential. Science (1980) 1.96
Increased expression of inducible nitric oxide synthase and cyclo-oxygenase-2 in the airway epithelium of asthmatic subjects and regulation by corticosteroid treatment. Thorax (2001) 1.95
Increased 8-isoprostane, a marker of oxidative stress, in exhaled condensate of asthma patients. Am J Respir Crit Care Med (1999) 1.92
Elevated levels of 8-iso-prostaglandin F2alpha in pericardial fluid of patients with heart failure: a potential role for in vivo oxidant stress in ventricular dilatation and progression to heart failure. Circulation (1998) 1.90
Increased F2-isoprostanes in Alzheimer's disease: evidence for enhanced lipid peroxidation in vivo. FASEB J (1998) 1.89
The recovery of platelet cyclooxygenase activity explains interindividual variability in responsiveness to low-dose aspirin in patients with and without diabetes. J Thromb Haemost (2012) 1.89
Increased formation of distinct F2 isoprostanes in hypercholesterolemia. Circulation (1999) 1.79
Biochemical and pharmacological characterization of the cyclooxygenase activity of human blood prostaglandin endoperoxide synthases. J Pharmacol Exp Ther (1994) 1.79
Nicotine effects on eicosanoid formation and hemostatic function: comparison of transdermal nicotine and cigarette smoking. J Am Coll Cardiol (1993) 1.76
Analysis of prostacyclin and thromboxane biosynthesis in cardiovascular disease. Circulation (1983) 1.73
The clinical significance of inhibition of renal prostaglandin synthesis. Kidney Int (1987) 1.69
Release of leukotriene C4 from human polymorphonuclear leucocytes as determined by radioimmunoassay. FEBS Lett (1982) 1.66
Demonstration of an inducible cyclooxygenase in human endothelial cells using antibodies raised against the carboxyl-terminal region of the cyclooxygenase-2. J Biol Chem (1993) 1.65
Effects of sulindac and ibuprofen in patients with chronic glomerular disease. Evidence for the dependence of renal function on prostacyclin. N Engl J Med (1984) 1.65
Brain metabolism in teenagers with attention-deficit hyperactivity disorder. Arch Gen Psychiatry (1993) 1.60
Evidence for a direct stimulatory effect of prostacyclin on renin release in man. J Clin Invest (1982) 1.57
Exhaled leukotrienes and prostaglandins in COPD. Thorax (2003) 1.55
Effect of oral prednisone on airway inflammatory mediators in atopic asthma. Am J Respir Crit Care Med (1994) 1.54
Human platelet/erythroleukemia cell prostaglandin G/H synthase: cDNA cloning, expression, and gene chromosomal assignment. FASEB J (1991) 1.54
Increased thromboxane biosynthesis in patients with acute cerebral ischemia. Stroke (1993) 1.54
Aspiration in acute stroke: a clinical study with videofluoroscopy. Q J Med (1993) 1.52
Effects of cyclo-oxygenase inhibition on exhaled eicosanoids in patients with COPD. Thorax (2005) 1.50
Generation of species cross-reactive aptamers using "toggle" SELEX. Mol Ther (2001) 1.49
Measurement of 6-oxo-PGF1 alpha in human plasma using gas chromatography-mass spectrometry. Prostaglandins (1979) 1.48
Improvement of renal function with selective thromboxane antagonism in lupus nephritis. N Engl J Med (1989) 1.46
Executive functioning in Alzheimer's disease and vascular dementia. Int J Geriatr Psychiatry (2010) 1.46
Increased thromboxane biosynthesis in patients with polycythemia vera: evidence for aspirin-suppressible platelet activation in vivo. Blood (1992) 1.45
Sandwich-type enzyme immunoassay for big endothelin-I in plasma: concentrations in healthy human subjects unaffected by sex or posture. Clin Chem (1997) 1.43
Biomarkers of oxidative stress study III. Effects of the nonsteroidal anti-inflammatory agents indomethacin and meclofenamic acid on measurements of oxidative products of lipids in CCl4 poisoning. Free Radic Biol Med (2005) 1.42
Differential inhibition of human prostaglandin endoperoxide synthase-1 and -2 by nonsteroidal anti-inflammatory drugs. J Physiol Pharmacol (1997) 1.41
Silver syndrome variant of hereditary spastic paraplegia: A locus to 4p and allelism with SPG4. Neurology (2008) 1.41
Benefits of animal research and the doctor's responsibility. BMJ (1990) 1.39
The costs and experiences of caring for sick and disabled geriatric patients--Australian observations. Aust J Public Health (1993) 1.39
Competitive enzyme immunoassay with monoclonal antibody for homovanillic acid measurement in human urine samples. Clin Chem (1997) 1.39
The natural history and clinical consequences of aspiration in acute stroke. QJM (1995) 1.39
Cellular distribution and karyophilic properties of matrix, integrase, and Vpr proteins from the human and simian immunodeficiency viruses. Exp Cell Res (2000) 1.38
In vivo formation of 8-Epi-prostaglandin F2 alpha is increased in hypercholesterolemia. Arterioscler Thromb Vasc Biol (1997) 1.38
Localization of distinct F2-isoprostanes in human atherosclerotic lesions. J Clin Invest (1997) 1.38
Radioimmunoassay measurement of prostaglandins E2 and F2alpha in human urine. J Endocrinol Invest (1979) 1.35
Cyclooxygenase-2 is widely expressed in atherosclerotic lesions affecting native and transplanted human coronary arteries and colocalizes with inducible nitric oxide synthase and nitrotyrosine particularly in macrophages. Arterioscler Thromb Vasc Biol (1999) 1.35
Systemic administration of endotoxin induces bronchopulmonary hyperreactivity dissociated from TNF-alpha formation and neutrophil sequestration into the murine lungs. J Immunol (1998) 1.33
Thromboxane biosynthesis and platelet function in type II diabetes mellitus. N Engl J Med (1990) 1.32
Paracetemol poisoning--a brief report. Ir Med J (1977) 1.32
The human thromboxane A2 receptor alpha isoform (TP alpha) functionally couples to the G proteins Gq and G11 in vivo and is activated by the isoprostane 8-epi prostaglandin F2 alpha. J Pharmacol Exp Ther (1997) 1.31
The use of venous pressure measurements and directional doppler recordings in distinguishing between superficial and deep valvular incompetence in patients with deep venous insufficiency. Br J Surg (1973) 1.30
Standard virtual biological parts: a repository of modular modeling components for synthetic biology. Bioinformatics (2010) 1.30
Aspirin and human platelets: from clinical trials to acetylation of cyclooxygenase and back. Trends Pharmacol Sci (1989) 1.26
Heart rate and blood pressure responses to carotid sinus massage in healthy elderly subjects. Age Ageing (1994) 1.25
Distinct roles of prostaglandin H synthases 1 and 2 in T-cell development. J Clin Invest (1999) 1.25
Interaction of vasculotropin/vascular endothelial cell growth factor with human umbilical vein endothelial cells: binding, internalization, degradation, and biological effects. J Cell Physiol (1991) 1.23
Analytical methods for thromboxane B2 measurement and validation of radioimmunoassay by gas liquid chromatography-mass spectrometry. Prostaglandins (1978) 1.21
Nitric oxide and endothelin secretion by brain microvessel endothelial cells: regulation by cyclic nucleotides. J Cell Physiol (1993) 1.20
Stimulation of leukotriene biosynthesis in human blood leukocytes by platelet-derived 12-hydroperoxy-icosatetraenoic acid. Proc Natl Acad Sci U S A (1982) 1.20
Preferential labeling of alpha-amino N-terminal groups in peptides by biotin: application to the detection of specific anti-peptide antibodies by enzyme immunoassays. J Immunol Methods (1996) 1.19
Oxidant stress and aspirin-insensitive thromboxane biosynthesis in severe unstable angina. Circulation (2000) 1.17
Radioimmunoassay of serum thromboxane B2: a simple method of assessing pharmacologic effects on platelet function. Adv Prostaglandin Thromboxane Res (1980) 1.17
Interpreting the clinical significance of the differential inhibition of cyclooxygenase-1 and cyclooxygenase-2. Rheumatology (Oxford) (1999) 1.16
Circadian rhythm of baroreflex reactivity and adrenergic vascular response. Cardiovasc Res (1980) 1.15
Enzyme immunoassays of eicosanoids using acetylcholinesterase. Methods Enzymol (1990) 1.15
Reappraisal of the clinical pharmacology of low-dose aspirin by comparing novel direct and traditional indirect biomarkers of drug action. J Thromb Haemost (2014) 1.15
The synovial prostaglandin system in chronic inflammatory arthritis: differential effects of steroidal and nonsteroidal anti-inflammatory drugs. Br J Pharmacol (1981) 1.15
Sanitation and Quality Control in the Fishery Industries. Am J Public Health Nations Health (1937) 1.15
Estimated rate of thromboxane secretion into the circulation of normal humans. J Clin Invest (1986) 1.15
Isolation and characterization of a dibasic selective metalloendopeptidase from rat testes that cleaves at the amino terminus of arginine residues. J Biol Chem (1994) 1.13
Early expression of cyclo-oxygenase-2 during sporadic colorectal carcinogenesis. J Pathol (1999) 1.12