Published in Int Immunol on June 01, 1995
gamma/delta and other unconventional T lymphocytes: what do they see and what do they do? Proc Natl Acad Sci U S A (1996) 1.73
IL-17 producing gammadelta T cells are required for a controlled inflammatory response after bleomycin-induced lung injury. Inflammation (2008) 1.49
Basal metabolic rate and the evolution of the adaptive immune system. Proc Biol Sci (2002) 1.25
Macrophage-mediated but gamma interferon-independent innate immune responses control the primary wave of Plasmodium yoelii parasitemia. Infect Immun (2007) 1.19
Protective efficacy of antigenic fractions in mouse models of cryptococcosis. Infect Immun (2004) 1.03
Splenic gammadelta T cells regulated by CD4+ T cells are required to control chronic Plasmodium chabaudi malaria in the B-cell-deficient mouse. Infect Immun (2006) 0.95
Gammadelta T cells but not NK cells are essential for cell-mediated immunity against Plasmodium chabaudi malaria. Infect Immun (2010) 0.93
An alphabeta T-cell-independent immunoprotective response towards gut coccidia is supported by gammadelta cells. Immunology (2000) 0.89
Enhancement of dendritic cell activation via CD40 ligand-expressing γδ T cells is responsible for protective immunity to Plasmodium parasites. Proc Natl Acad Sci U S A (2012) 0.86
Gammaherpesvirus Co-infection with Malaria Suppresses Anti-parasitic Humoral Immunity. PLoS Pathog (2015) 0.83
Murine gamma delta T lymphocytes elicited during Plasmodium yoelii infection respond to Plasmodium heat shock proteins. Infect Immun (1999) 0.83
Exacerbation of Plasmodium chabaudi malaria in mice by depletion of TCR alpha beta+ T cells, but not TCR gamma delta+ T cells. Immunology (1996) 0.78
Enhanced differentiation of intraepithelial lymphocytes in the intestine of polymeric immunoglobulin receptor-deficient mice. Immunology (2015) 0.75
Somatic generation of antibody diversity. Nature (1983) 28.06
Functional annotation of a full-length mouse cDNA collection. Nature (2001) 23.61
RAG-1-deficient mice have no mature B and T lymphocytes. Cell (1992) 20.97
A tissue-specific transcription enhancer element is located in the major intron of a rearranged immunoglobulin heavy chain gene. Cell (1983) 18.86
Sequences at the somatic recombination sites of immunoglobulin light-chain genes. Nature (1979) 11.83
Two types of somatic recombination are necessary for the generation of complete immunoglobulin heavy-chain genes. Nature (1980) 10.19
B lineage--specific interactions of an immunoglobulin enhancer with cellular factors in vivo. Science (1985) 9.73
A complete immunoglobulin gene is created by somatic recombination. Cell (1978) 8.53
Subregion- and cell type-restricted gene knockout in mouse brain. Cell (1996) 8.02
Sequences of mouse immunoglobulin light chain genes before and after somatic changes. Cell (1978) 7.53
The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory. Cell (1996) 6.96
Sequence of a mouse germ-line gene for a variable region of an immunoglobulin light chain. Proc Natl Acad Sci U S A (1978) 6.80
Ordered rearrangement of immunoglobulin heavy chain variable region segments. EMBO J (1984) 6.67
Spontaneous development of inflammatory bowel disease in T cell receptor mutant mice. Cell (1993) 5.99
Evidence for somatic rearrangement of immunoglobulin genes coding for variable and constant regions. Proc Natl Acad Sci U S A (1976) 5.81
BDNF regulates the maturation of inhibition and the critical period of plasticity in mouse visual cortex. Cell (1999) 5.63
Deficient hippocampal long-term potentiation in alpha-calcium-calmodulin kinase II mutant mice. Science (1992) 5.46
Organization, structure, and assembly of immunoglobulin heavy chain diversity DNA segments. J Exp Med (1982) 5.37
Domains and the hinge region of an immunoglobulin heavy chain are encoded in separate DNA segments. Nature (1979) 5.35
Evidence for a differential avidity model of T cell selection in the thymus. Cell (1994) 5.24
Complete primary structure of a heterodimeric T-cell receptor deduced from cDNA sequences. Nature (1984) 5.19
Impaired spatial learning in alpha-calcium-calmodulin kinase II mutant mice. Science (1992) 5.03
TAP1 mutant mice are deficient in antigen presentation, surface class I molecules, and CD4-8+ T cells. Cell (1992) 4.76
Reduced stress defense in heme oxygenase 1-deficient cells. Proc Natl Acad Sci U S A (1997) 4.74
Junctional sequences of T cell receptor gamma delta genes: implications for gamma delta T cell lineages and for a novel intermediate of V-(D)-J joining. Cell (1989) 4.65
Heme oxygenase 1 is required for mammalian iron reutilization. Proc Natl Acad Sci U S A (1997) 4.63
Developmental regulation of T-cell receptor gene expression. Nature (1985) 4.53
Skeletal and CNS defects in Presenilin-1-deficient mice. Cell (1997) 4.50
Gamma/delta cells. Annu Rev Immunol (1993) 4.35
High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein T cell receptor transgenic mice. Cell (1994) 4.34
Identification of D segments of immunoglobulin heavy-chain genes and their rearrangement in T lymphocytes. Nature (1981) 4.26
Identification and nucleotide sequence of a diversity DNA segment (D) of immunoglobulin heavy-chain genes. Nature (1981) 4.19
T cell receptor delta gene mutant mice: independent generation of alpha beta T cells and programmed rearrangements of gamma delta TCR genes. Cell (1993) 4.18
Cell-type-specific contacts to immunoglobulin enhancers in nuclei. Nature (1985) 3.94
Selective deletion of leptin receptor in neurons leads to obesity. J Clin Invest (2001) 3.82
Forebrain-specific calcineurin knockout selectively impairs bidirectional synaptic plasticity and working/episodic-like memory. Cell (2001) 3.55
Homing of a gamma delta thymocyte subset with homogeneous T-cell receptors to mucosal epithelia. Nature (1990) 3.55
Structure, organization, and somatic rearrangement of T cell gamma genes. Cell (1985) 3.49
Different roles of alpha beta and gamma delta T cells in immunity against an intracellular bacterial pathogen. Nature (1993) 3.47
A third rearranged and expressed gene in a clone of cytotoxic T lymphocytes. Nature (1984) 3.46
Differentiation of embryonic stem cell lines generated from adult somatic cells by nuclear transfer. Science (2001) 3.44
Transcription of mouse kappa chain genes: implications for allelic exclusion. Proc Natl Acad Sci U S A (1980) 3.38
Activation of the c-myc gene by translocation: a model for translational control. Proc Natl Acad Sci U S A (1983) 3.36
Deficient cerebellar long-term depression and impaired motor learning in mGluR1 mutant mice. Cell (1994) 3.35
Cloning of an immunoglobulin variable region gene from mouse embryo. Proc Natl Acad Sci U S A (1977) 3.21
Cell type-specific enhancer element associated with a mouse MHC gene, E beta. Nature (1984) 3.16
Complete primary structures of the E beta chain and gene of the mouse major histocompatibility complex. Proc Natl Acad Sci U S A (1983) 3.09
Preserved acute pain and reduced neuropathic pain in mice lacking PKCgamma. Science (1997) 2.98
Variable and constant parts of the immunoglobulin light chain gene of a mouse myeloma cell are 1250 nontranslated bases apart. Proc Natl Acad Sci U S A (1977) 2.93
Activation of a translocated human c-myc gene by an enhancer in the immunoglobulin heavy-chain locus. Nature (1984) 2.93
Diversity of murine gamma genes and expression in fetal and adult T lymphocytes. Nature (1986) 2.89
Intestinal intraepithelial lymphocytes are a distinct set of gamma delta T cells. Nature (1988) 2.89
The role of DNA rearrangement and alternative RNA processing in the expression of immunoglobulin delta genes. Cell (1981) 2.85
Exon shuffling generates an immunoglobulin heavy chain gene. Proc Natl Acad Sci U S A (1980) 2.80
Monoclonal antibodies specific to native murine T-cell receptor gamma delta: analysis of gamma delta T cells during thymic ontogeny and in peripheral lymphoid organs. Proc Natl Acad Sci U S A (1989) 2.79
Somatic changes in the content and context of immunoglobulin genes. Cold Spring Harb Symp Quant Biol (1977) 2.73
Impaired hippocampal representation of space in CA1-specific NMDAR1 knockout mice. Cell (1996) 2.62
DNA clones containing mouse immunoglobulin kappa chain genes isolated by in vitro packaging into phage lambda coats. Proc Natl Acad Sci U S A (1978) 2.60
Cortex-restricted disruption of NMDAR1 impairs neuronal patterns in the barrel cortex. Nature (2000) 2.60
Limited diversity of the rearranged T-cell gamma gene. Nature (1985) 2.58
Bcl-2 promotes regeneration of severed axons in mammalian CNS. Nature (1997) 2.57
Myelin basic protein-specific T helper 2 (Th2) cells cause experimental autoimmune encephalomyelitis in immunodeficient hosts rather than protect them from the disease. J Exp Med (1997) 2.51
Elimination of cocaine-induced hyperactivity and dopamine-mediated neurophysiological effects in dopamine D1 receptor mutant mice. Cell (1994) 2.46
Extrathymic origin of intestinal intraepithelial lymphocytes bearing T-cell antigen receptor gamma delta. Proc Natl Acad Sci U S A (1991) 2.46
Nobel laureates' letter to President Bush. Washington Post (2001) 2.43
TAP1-dependent peptide translocation in vitro is ATP dependent and peptide selective. Cell (1993) 2.43
Electrophoretically homogeneous myeloma light chain mRNA and its translation in vitro. Biochem Biophys Res Commun (1973) 2.42
Structure and emergence of specific olfactory glomeruli in the mouse. J Neurosci (2001) 2.40
Altered peptidase and viral-specific T cell response in LMP2 mutant mice. Immunity (1994) 2.39
Onset of TCR-beta gene rearrangement and role of TCR-beta expression during CD3-CD4-CD8- thymocyte differentiation. J Immunol (1994) 2.38
Unusual organization and diversity of T-cell receptor alpha-chain genes. Nature (1985) 2.36
Recognition of the product of a novel MHC TL region gene (27b) by a mouse gamma delta T cell receptor. Cell (1990) 2.33
Somatic mutation creates diversity in the major group of mouse immunoglobulin kappa light chains. J Exp Med (1984) 2.33
Attachment of an anti-receptor antibody to non-target cells renders them susceptible to lysis by a clone of cytotoxic T lymphocytes. Proc Natl Acad Sci U S A (1984) 2.32
Variable patterns of axonal projections of sensory neurons in the mouse vomeronasal system. Cell (1999) 2.26
Localization of gamma/delta T cells to the intestinal epithelium is independent of normal microbial colonization. J Exp Med (1990) 2.23
Homeostatic regulation of intestinal epithelia by intraepithelial gamma delta T cells. Proc Natl Acad Sci U S A (1995) 2.21
Diversity of gamma delta T-cell receptors on murine intestinal intra-epithelial lymphocytes. Nature (1989) 2.21
Abnormal fear response and aggressive behavior in mutant mice deficient for alpha-calcium-calmodulin kinase II. Science (1994) 2.20
Reiteration frequency of immunoglobulin light chain genes: further evidence for somatic generation of antibody diversity. Proc Natl Acad Sci U S A (1976) 2.20
Targeted disruption of semaphorin 3C leads to persistent truncus arteriosus and aortic arch interruption. Development (2001) 2.15
Modified hippocampal long-term potentiation in PKC gamma-mutant mice. Cell (1993) 2.14
Immunoglobulin gene rearrangement in immature B cells. Science (1980) 2.14
Restoration of early thymocyte differentiation in T-cell receptor beta-chain-deficient mutant mice by transmembrane signaling through CD3 epsilon. Proc Natl Acad Sci U S A (1993) 2.06
Dopamine D1 receptor mutant mice are deficient in striatal expression of dynorphin and in dopamine-mediated behavioral responses. Cell (1994) 2.05
Evidence for somatic generation of antibody diversity. Proc Natl Acad Sci U S A (1974) 2.03
Peptide contributes to the specificity of positive selection of CD8+ T cells in the thymus. Cell (1993) 1.96
Mice cloned from embryonic stem cells. Proc Natl Acad Sci U S A (1999) 1.93
Diversity and joining segments of mouse immunoglobulin heavy chain genes are closely linked and in the same orientation: implications for the joining mechanism. Proc Natl Acad Sci U S A (1983) 1.93
Cytokine imbalance and autoantibody production in T cell receptor-alpha mutant mice with inflammatory bowel disease. J Exp Med (1996) 1.91
Different gamma delta T-cell receptors are expressed on thymocytes at different stages of development. Proc Natl Acad Sci U S A (1989) 1.91
PKC gamma mutant mice exhibit mild deficits in spatial and contextual learning. Cell (1993) 1.84
Recognition of a self major histocompatibility complex TL region product by gamma delta T-cell receptors. Proc Natl Acad Sci U S A (1989) 1.84
Brain-derived neurotrophic factor overexpression induces precocious critical period in mouse visual cortex. J Neurosci (1999) 1.82
Whisker-related neuronal patterns fail to develop in the trigeminal brainstem nuclei of NMDAR1 knockout mice. Cell (1994) 1.82
Secondary, tertiary, and quaternary structure of T-cell-specific immunoglobulin-like polypeptide chains. Proc Natl Acad Sci U S A (1986) 1.81