Intermediates of adeno-associated virus type 2 assembly: identification of soluble complexes containing Rep and Cap proteins.

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Published in J Virol on September 01, 1995

Authors

A Wistuba1, S Weger, A Kern, J A Kleinschmidt

Author Affiliations

1: Deutsches Krebsforschungszentrum, Forschungsschwerpunkt Angewandte Tumorvirologie, Heidelberg, Germany.

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Use of T7 RNA polymerase to direct expression of cloned genes. Methods Enzymol (1990) 61.47

ADENOVIRUS-ASSOCIATED DEFECTIVE VIRUS PARTICLES. Science (1965) 9.77

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An octamer of histones in chromatin and free in solution. Proc Natl Acad Sci U S A (1975) 7.35

Site-specific integration by adeno-associated virus. Proc Natl Acad Sci U S A (1990) 7.06

Targeted integration of adeno-associated virus (AAV) into human chromosome 19. EMBO J (1991) 6.13

The AAV origin binding protein Rep68 is an ATP-dependent site-specific endonuclease with DNA helicase activity. Cell (1990) 5.98

Genetics of adeno-associated virus: isolation and preliminary characterization of adeno-associated virus type 2 mutants. J Virol (1984) 5.89

Genetic analysis of adeno-associated virus: properties of deletion mutants constructed in vitro and evidence for an adeno-associated virus replication function. J Virol (1984) 4.98

Herpes simplex virus types 1 and 2 completely help adenovirus-associated virus replication. J Virol (1981) 3.72

Positive and negative autoregulation of the adeno-associated virus type 2 genome. J Virol (1986) 3.67

Factors that bind to adeno-associated virus terminal repeats. J Virol (1989) 3.56

Parvovirus replication. Microbiol Rev (1990) 3.37

Negative and positive regulation in trans of gene expression from adeno-associated virus vectors in mammalian cells by a viral rep gene product. Mol Cell Biol (1986) 3.34

Structural proteins of adenovirus-associated viruses. J Virol (1971) 3.03

Mutagenesis of an AUG codon in the adeno-associated virus rep gene: effects on viral DNA replication. Virology (1989) 2.91

Partial purification of adeno-associated virus Rep78, Rep52, and Rep40 and their biochemical characterization. J Virol (1992) 2.84

Adeno-associated viruses: an update. Adv Virus Res (1987) 2.71

Identification of nuclear proteins that specifically interact with adeno-associated virus type 2 inverted terminal repeat hairpin DNA. J Virol (1989) 2.60

Characterization of adenovirus-associated virus-induced polypeptides in KB cells. J Virol (1978) 2.40

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In vitro replication of adeno-associated virus DNA. J Virol (1994) 2.09

Alternate mRNA splicing is required for synthesis of adeno-associated virus VP1 capsid protein. J Virol (1988) 2.03

Synthesis of adeno-associated virus structural proteins requires both alternative mRNA splicing and alternative initiations from a single transcript. J Virol (1988) 1.89

Characterization of adeno-associated virus rep proteins in human cells by antibodies raised against rep expressed in Escherichia coli. Virology (1987) 1.85

Adeno-associated virus rep proteins produced in insect and mammalian expression systems: wild-type and dominant-negative mutant proteins bind to the viral replication origin. Virology (1991) 1.84

Assembly of adeno-associated virus. Virology (1980) 1.71

Host range transforming gene of polyoma virus plays a role in virus assembly. Proc Natl Acad Sci U S A (1983) 1.69

Adeno-associated virus rep protein synthesis during productive infection. J Virol (1989) 1.54

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Virion assembly defect of polyomavirus hr-t mutants: underphosphorylation of major capsid protein VP1 before viral DNA encapsidation. J Virol (1985) 1.50

Organization of the adeno-associated virus (AAV) capsid gene: mapping of a minor spliced mRNA coding for virus capsid protein 1. Virology (1988) 1.31

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Simian virus 40 large T antigen host range domain functions in virion assembly. J Virol (1994) 0.95

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[Socioeconomic incidences and prognostic factors of low back pain caused by occupational injuries among the hospital personnel of Grenoble University Hospital Center]. Rev Rhum Ed Fr (1993) 1.39

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Rhizocticin A, an antifungal phosphono-oligopeptide of Bacillus subtilis ATCC 6633: biological properties. Arch Microbiol (1990) 1.18

A nucleolar skeleton of protein filaments demonstrated in amplified nucleoli of Xenopus laevis. J Cell Biol (1981) 1.15

The 22 S cylinder particles of Xenopus laevis. I. Biochemical and electron microscopic characterization. Eur J Cell Biol (1983) 1.15

The adeno-associated virus type 2 regulatory proteins rep78 and rep68 interact with the transcriptional coactivator PC4. J Virol (1999) 1.14

Purification of Thermotoga maritima enzymes for the degradation of cellulosic materials. Appl Environ Microbiol (1995) 1.13

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High-level expression of adeno-associated virus (AAV) Rep78 or Rep68 protein is sufficient for infectious-particle formation by a rep-negative AAV mutant. J Virol (1995) 1.07

High mobility group proteins of amphibian oocytes: a large storage pool of a soluble high mobility group-1-like protein and involvement in transcriptional events. J Cell Biol (1983) 1.06

Novel random peptide libraries displayed on AAV serotype 9 for selection of endothelial cell-directed gene transfer vectors. Gene Ther (2011) 1.05

Heart-targeted adeno-associated viral vectors selected by in vivo biopanning of a random viral display peptide library. Gene Ther (2010) 1.05

The 22 S cylinder particles of Xenopus laevis. II. Immunological characterization and localization of their proteins in tissues and cultured cells. Eur J Cell Biol (1983) 1.03

Specific and sensitive IgG4 immunodiagnosis of onchocerciasis with a recombinant 33 kD Onchocerca volvulus protein (Ov33). Trop Med Parasitol (1992) 1.03

Hydro-MRI in Crohn's disease: appraisal of disease activity. Invest Radiol (2000) 1.01

Transcranial color-coded duplex sonography of intracranial veins and sinuses in adults. Reference data from 130 volunteers. Stroke (1999) 1.00

Cell lines inducibly expressing the adeno-associated virus (AAV) rep gene: requirements for productive replication of rep-negative AAV mutants. J Virol (1994) 0.99

The glutamine synthetase from Azotobacter vinelandii: purification, characterization, regulation and localization. Eur J Biochem (1978) 0.99

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Two-tone suppression and combination tone generation as computations performed by the Hopf cochlea. Phys Rev Lett (2004) 0.95

Acanthocheilonema viteae: vaccination of jirds with irradiation-attenuated stage-3 larvae and with exported larval antigens. Exp Parasitol (1991) 0.93

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Fast spike pattern detection using the correlation integral. Phys Rev E Stat Nonlin Soft Matter Phys (2004) 0.91

Highly efficient and specific modulation of cardiac calcium homeostasis by adenovector-derived short hairpin RNA targeting phospholamban. Gene Ther (2006) 0.90

Assembly and function of integrin receptors is dependent on opposing alpha and beta cytoplasmic domains. Mol Biol Cell (1995) 0.90

Selective inactivation of nitrogenase in Azotobacter vinelandii batch cultures. J Bacteriol (1976) 0.89

3-D coculture of hepatic sinusoidal cells with primary hepatocytes-design of an organotypical model. Exp Cell Res (1996) 0.89

A generalization of the van-der-Pol oscillator underlies active signal amplification in Drosophila hearing. Eur Biophys J (2006) 0.89

Proteins regulating actin assembly in oogenesis and early embryogenesis of Xenopus laevis: gelsolin is the major cytoplasmic actin-binding protein. J Cell Biol (1988) 0.88

Prevalence of antibodies to Borrelia burgdorferi and tick-borne encephalitis virus in an endemic region in southern Germany. Zentralbl Bakteriol (1997) 0.86

Molecular cloning of an immunodominant antigen of Onchocerca volvulus. J Exp Med (1988) 0.86

Essential auditory contrast-sharpening is preneuronal. Proc Natl Acad Sci U S A (2004) 0.85

mdr1/P-glycoprotein gene segments analyzed from various human leukemic cell lines exhibiting different multidrug resistance profiles. Biochem Biophys Res Commun (1990) 0.85

Evaluation of pedal lymphangiography in staging non-seminomatous testicular carcinoma. J Urol (1977) 0.85

Limit cycles, noise, and chaos in hearing. Microsc Res Tech (2004) 0.84

Ultrastructure of the approximately 26S complex containing the approximately 20S cylinder particle (multicatalytic proteinase/proteasome). Eur J Cell Biol (1991) 0.84

Biotransformation of cerivastatin in mice, rats, and dogs in vivo. Drug Metab Dispos (1998) 0.83

Acanthocheilonema viteae: vaccination with irradiated L3 induces resistance in three species of rodents (Meriones unguiculatus, Mastomys coucha, Mesocricetus auratus). Trop Med Int Health (1997) 0.82

[Second reading of breast imaging at the hospital department of radiology: reasonable or waste of money?]. Rofo (2006) 0.82

Reactivation of DNA replication in erythrocyte nuclei by Xenopus egg extract involves energy-dependent chromatin decondensation and changes in histone phosphorylation. Exp Cell Res (1992) 0.82

Superior gene transfer into solid tumour cells than into human mobilised peripheral blood progenitor cells using helpervirus-free adeno-associated viral vector stocks. Eur J Cancer (1999) 0.82

Metabolic products from microorganisms. 230. Amiclenomycin-peptides, new antimetabolites of biotin. Taxonomy, fermentation and biological properties. J Antibiot (Tokyo) (1985) 0.81

Antibody responses in forest and savanna onchocerciasis in Ivory Coast. Trop Med Parasitol (1987) 0.81

[Assessment of inflammatory activity in Crohn disease with hydro-MRI]. Rofo (2000) 0.81

[Serological total diagnosis of syphilis]. Dermatol Monatsschr (1975) 0.79

The membrane-cytoplasm interface of integrin alpha subunits is critical for receptor latency. Mol Biol Cell (1996) 0.79

Differential expression of a recombinant adeno-associated virus 2 vector in human CD34+ cells and breast cancer cells. Cancer Gene Ther (2000) 0.79

Characterization of an immunodominant Onchocerca volvulus antigen with patient sera and a monoclonal antibody. J Exp Med (1988) 0.79

[Cerebral manifestations of progressive facial hemiatrophy (Romberg's disease). Nuclear spin tomographic findings and literature review]. Radiologe (1993) 0.79

Electrocardiographic changes in patients with brain tumors. Arch Neurol (1995) 0.79

Augmented transgene expression in transformed cells using a parvoviral hybrid vector. Cancer Gene Ther (2008) 0.79

Tamoxifen-regulated adenoviral E1A chimeras for the control of tumor selective oncolytic adenovirus replication in vitro and in vivo. Gene Ther (2006) 0.78

Induction of sTNF-R1 and sTNF-R2 by interferon beta-1b in correlation with clinical and MRI activity. Acta Neurol Scand (2001) 0.78

[Preparation, testing and use of a monospecific FITC-labelled antigonococcal serum]. Dermatol Monatsschr (1973) 0.78

Soluble and cell surface ICAM-1 as markers for disease activity in multiple sclerosis. Acta Neurol Scand (1998) 0.78

Soluble and cell surface ICAM-3 in blood and cerebrospinal fluid of patients with multiple sclerosis: influence of methylprednisolone treatment and relevance as markers for disease activity. Acta Neurol Scand (2000) 0.78

[Toxic shock syndrome in a 29-year-old patient]. MMW Munch Med Wochenschr (1981) 0.78

Computer-controlled discontinuous rotating gel electrophoresis for separation of very large DNA molecules. Anal Biochem (1989) 0.77

Tissue-specific gene expression in medullary thyroid carcinoma cells employing calcitonin regulatory elements and AAV vectors. Cancer Gene Ther (2001) 0.76

[Radiotherapy of humero-scapular periarthritis using ultra-hard photons. Evaluation by MRI findings]. Radiologe (1998) 0.76

Preclinical study on gene therapy of cervical carcinoma using adeno-associated virus vectors. Cancer Gene Ther (2000) 0.76