Assembly of viruslike particles by recombinant structural proteins of adeno-associated virus type 2 in insect cells.

PubWeight™: 1.52‹?› | Rank: Top 4%

🔗 View Article (PMC 240317)

Published in J Virol on December 01, 1992

Authors

M Ruffing1, H Zentgraf, J A Kleinschmidt

Author Affiliations

1: Deutsches Krebsforschungszentrum, Forschungsschwerpunkt Angewandte Tumorvirologie, Heidelberg, Germany.

Articles citing this

Mutational analysis of the adeno-associated virus type 2 (AAV2) capsid gene and construction of AAV2 vectors with altered tropism. J Virol (2000) 3.27

Monoclonal antibodies against the adeno-associated virus type 2 (AAV-2) capsid: epitope mapping and identification of capsid domains involved in AAV-2-cell interaction and neutralization of AAV-2 infection. J Virol (2000) 3.10

Adeno-associated virus vectors preferentially transduce cells in S phase. Proc Natl Acad Sci U S A (1994) 2.62

DNA helicase-mediated packaging of adeno-associated virus type 2 genomes into preformed capsids. EMBO J (2001) 2.43

Subcellular compartmentalization of adeno-associated virus type 2 assembly. J Virol (1997) 2.31

Intermediates of adeno-associated virus type 2 assembly: identification of soluble complexes containing Rep and Cap proteins. J Virol (1995) 1.86

A viral assembly factor promotes AAV2 capsid formation in the nucleolus. Proc Natl Acad Sci U S A (2010) 1.78

Adenovirus-facilitated nuclear translocation of adeno-associated virus type 2. J Virol (2002) 1.77

Adeno-associated virus type 2 VP2 capsid protein is nonessential and can tolerate large peptide insertions at its N terminus. J Virol (2004) 1.67

Efficient gene transfer into nondividing cells by adeno-associated virus-based vectors. J Virol (1994) 1.63

Adeno-associated virus: from defective virus to effective vector. Virol J (2005) 1.60

A beta-stranded motif drives capsid protein oligomers of the parvovirus minute virus of mice into the nucleus for viral assembly. J Virol (2000) 1.32

In vitro packaging of adeno-associated virus DNA. J Virol (1998) 1.22

Adeno-associated virus type 2 protein interactions: formation of pre-encapsidation complexes. J Virol (1999) 1.20

Synthesis of viruslike particles by expression of the putative capsid protein of Leishmania RNA virus in a recombinant baculovirus expression system. J Virol (1994) 1.17

Nuclear transport of the major capsid protein is essential for adeno-associated virus capsid formation. J Virol (1999) 1.16

Manufacturing of recombinant adeno-associated viral vectors for clinical trials. Mol Ther Methods Clin Dev (2016) 1.05

Proteolytic mapping of the adeno-associated virus capsid. Mol Ther (2006) 1.03

Cell lines inducibly expressing the adeno-associated virus (AAV) rep gene: requirements for productive replication of rep-negative AAV mutants. J Virol (1994) 0.99

Evidence of prior exposure to human bocavirus as determined by a retrospective serological study of 404 serum samples from adults in the United States. Clin Vaccine Immunol (2009) 0.92

Addition of six-His-tagged peptide to the C terminus of adeno-associated virus VP3 does not affect viral tropism or production. J Virol (2002) 0.86

OneBac 2.0: Sf9 Cell Lines for Production of AAV5 Vectors with Enhanced Infectivity and Minimal Encapsidation of Foreign DNA. Hum Gene Ther (2015) 0.83

Mutational analysis of the capsid protein of Leishmania RNA virus LRV1-4. J Virol (1994) 0.78

Capsid protein expression and adeno-associated virus like particles assembly in Saccharomyces cerevisiae. Microb Cell Fact (2012) 0.76

The role of nuclear localization signal in parvovirus life cycle. Virol J (2017) 0.75

Articles cited by this

Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (1970) 1528.65

DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci U S A (1977) 790.54

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci U S A (1979) 365.71

Use of T7 RNA polymerase to direct expression of cloned genes. Methods Enzymol (1990) 61.47

High-efficiency transformation of mammalian cells by plasmid DNA. Mol Cell Biol (1987) 43.61

A short amino acid sequence able to specify nuclear location. Cell (1984) 21.17

The rapid generation of oligonucleotide-directed mutations at high frequency using phosphorothioate-modified DNA. Nucleic Acids Res (1985) 12.11

Sequence requirements for nuclear location of simian virus 40 large-T antigen. Nature (1984) 10.52

Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: identification of a class of bipartite nuclear targeting sequence. Cell (1991) 9.96

An octamer of histones in chromatin and free in solution. Proc Natl Acad Sci U S A (1975) 7.35

Protein import into the cell nucleus. Annu Rev Cell Biol (1986) 7.04

Helper-free stocks of recombinant adeno-associated viruses: normal integration does not require viral gene expression. J Virol (1989) 6.69

Genetics of adeno-associated virus: isolation and preliminary characterization of adeno-associated virus type 2 mutants. J Virol (1984) 5.89

Construction and characterization of an SV40 mutant defective in nuclear transport of T antigen. Cell (1984) 5.81

Established insect cell line from the cabbage looper, Trichoplusia ni. Nature (1970) 5.53

Synthetic peptides as nuclear localization signals. Nature (1986) 5.35

Genetic analysis of adeno-associated virus: properties of deletion mutants constructed in vitro and evidence for an adeno-associated virus replication function. J Virol (1984) 4.98

Induction of nuclear transport with a synthetic peptide homologous to the SV40 T antigen transport signal. Cell (1986) 4.56

Amino acid sequences that determine the nuclear localization of yeast histone 2B. Mol Cell Biol (1987) 3.31

High level expression of nonfused foreign genes with Autographa californica nuclear polyhedrosis virus expression vectors. Virology (1989) 3.31

Direct mapping of adeno-associated virus capsid proteins B and C: a possible ACG initiation codon. Proc Natl Acad Sci U S A (1985) 3.31

Adeno-associated viruses: an update. Adv Virus Res (1987) 2.71

Self-assembled B19 parvovirus capsids, produced in a baculovirus system, are antigenically and immunogenically similar to native virions. Proc Natl Acad Sci U S A (1991) 2.55

Characterization of adenovirus-associated virus-induced polypeptides in KB cells. J Virol (1978) 2.40

Eukaryotic translational control: adeno-associated virus protein synthesis is affected by a mutation in the adenovirus DNA-binding protein. Proc Natl Acad Sci U S A (1981) 2.08

Alternate mRNA splicing is required for synthesis of adeno-associated virus VP1 capsid protein. J Virol (1988) 2.03

The adeno-associated virus rep gene suppresses herpes simplex virus-induced DNA amplification. J Virol (1990) 2.00

Synthesis of adeno-associated virus structural proteins requires both alternative mRNA splicing and alternative initiations from a single transcript. J Virol (1988) 1.89

Colocalization of adeno-associated virus Rep and capsid proteins in the nuclei of infected cells. J Virol (1992) 1.86

Adeno-associated virus proteins: origin of the capsid components. J Virol (1984) 1.84

Nuclear transport of adenovirus DNA polymerase is facilitated by interaction with preterminal protein. Cell (1988) 1.81

Assembly of empty capsids by using baculovirus recombinants expressing human parvovirus B19 structural proteins. J Virol (1991) 1.75

Assembly of adeno-associated virus. Virology (1980) 1.71

Characterization of nuclear targeting signal of hepatitis delta antigen: nuclear transport as a protein complex. J Virol (1992) 1.63

Nucleosome assembly in vitro: separate histone transfer and synergistic interaction of native histone complexes purified from nuclei of Xenopus laevis oocytes. EMBO J (1990) 1.41

Simian virus 40 Vp2/3 small structural proteins harbor their own nuclear transport signal. Virology (1991) 1.40

Canine parvovirus empty capsids produced by expression in a baculovirus vector: use in analysis of viral properties and immunization of dogs. J Gen Virol (1992) 1.34

Structural proteins of adenovirus-associated virus: subspecies and their relatedness. J Virol (1983) 1.34

Organization of the adeno-associated virus (AAV) capsid gene: mapping of a minor spliced mRNA coding for virus capsid protein 1. Virology (1988) 1.31

The intranuclear location of simian virus 40 polypeptides VP2 and VP3 depends on a specific amino acid sequence. J Virol (1987) 1.29

Two independent signals, a nuclear localization signal and a Vp1-interactive signal, reside within the carboxy-35 amino acids of SV40 Vp3. Virology (1990) 1.13

Expression of polyomavirus virion proteins by a vaccinia virus vector: association of VP1 and VP2 with the nuclear framework. J Virol (1987) 1.10

Adeno-associated viruses having nonsense mutations in the capsid genes: growth in mammalian cells containing an inducible amber suppressor. Virology (1991) 1.08

Articles by these authors

Novel tools for production and purification of recombinant adenoassociated virus vectors. Hum Gene Ther (1998) 4.03

The spacer peptide between human immunodeficiency virus capsid and nucleocapsid proteins is essential for ordered assembly and viral infectivity. J Virol (1995) 3.80

Conversion of bacteriophage fd into an efficient single-stranded DNA vector system. Mol Gen Genet (1980) 3.57

Identification of a heparin-binding motif on adeno-associated virus type 2 capsids. J Virol (2003) 3.25

Transposition of a DNA sequence determining kanamycin resistance into the single-stranded genome of bacteriophage fd. Mol Gen Genet (1978) 3.19

Monoclonal antibodies against the adeno-associated virus type 2 (AAV-2) capsid: epitope mapping and identification of capsid domains involved in AAV-2-cell interaction and neutralization of AAV-2 infection. J Virol (2000) 3.10

Proteinase yscE, the yeast proteasome/multicatalytic-multifunctional proteinase: mutants unravel its function in stress induced proteolysis and uncover its necessity for cell survival. EMBO J (1991) 3.01

Construction of an infectious DNA clone of the full-length human spumaretrovirus genome and mutagenesis of the bel 1 gene. Virology (1991) 2.70

DNA helicase-mediated packaging of adeno-associated virus type 2 genomes into preformed capsids. EMBO J (2001) 2.43

Hormone-dependent terminal differentiation in vitro of chicken erythroleukemia cells transformed by ts mutants of avian erythroblastosis virus. Cell (1982) 2.33

Subcellular compartmentalization of adeno-associated virus type 2 assembly. J Virol (1997) 2.31

Foamy virus capsids require the cognate envelope protein for particle export. J Virol (1999) 2.30

Origin of replication in episomal bovine papilloma virus type 1 DNA isolated from transformed cells. EMBO J (1984) 2.26

Molecular characterization of a karyophilic, histone-binding protein: cDNA cloning, amino acid sequence and expression of nuclear protein N1/N2 of Xenopus laevis. EMBO J (1986) 2.25

Papillomavirus capsid binding and uptake by cells from different tissues and species. J Virol (1995) 2.24

Distinct 19 S and 20 S subcomplexes of the 26 S proteasome and their distribution in the nucleus and the cytoplasm. J Biol Chem (1994) 2.23

Foamy virus particle formation. J Virol (1998) 2.22

Higher order structure of simian virus 40 chromatin. Science (1978) 2.16

Isolation and characterization of the human tyrosine aminotransferase gene. Nucleic Acids Res (1990) 2.15

Murine genomic DNA sequences replicating autonomously in mouse L cells. Cell (1988) 2.14

A transcription enhancer acts in vitro over distances of hundreds of base-pairs on both circular and linear templates but not on chromatin-reconstituted DNA. J Mol Biol (1984) 2.09

Enhancement of capsid gene expression: preparing the human papillomavirus type 16 major structural gene L1 for DNA vaccination purposes. J Virol (2001) 2.02

The duck hepatitis B virus DNA polymerase is tightly associated with the viral core structure and unable to switch to an exogenous template. Virology (1988) 1.94

TIF-IA, the factor mediating growth-dependent control of ribosomal RNA synthesis, is the mammalian homolog of yeast Rrn3p. EMBO Rep (2000) 1.91

Intermediates of adeno-associated virus type 2 assembly: identification of soluble complexes containing Rep and Cap proteins. J Virol (1995) 1.86

A large-tumor-antigen-specific monoclonal antibody inhibits DNA replication of simian virus 40 minichromosomes in an in vitro elongation system. J Virol (1985) 1.85

Active foamy virus proteinase is essential for virus infectivity but not for formation of a Pol polyprotein. J Virol (1995) 1.81

Differentially expressed bovine cytokeratin genes. Analysis of gene linkage and evolutionary conservation of 5'-upstream sequences. EMBO J (1987) 1.80

A particle-associated glycoprotein signal peptide essential for virus maturation and infectivity. J Virol (2001) 1.80

Isolation and characterization of the rat tyrosine aminotransferase gene. Proc Natl Acad Sci U S A (1984) 1.77

Co-existence of two different types of soluble histone complexes in nuclei of Xenopus laevis oocytes. J Biol Chem (1985) 1.76

Interaction of Xenopus lamins A and LII with chromatin in vitro mediated by a sequence element in the carboxyterminal domain. Exp Cell Res (1991) 1.71

Mutational analysis of adeno-associated virus Rep protein-mediated inhibition of heterologous and homologous promoters. J Virol (1995) 1.71

Biochemical and ultrastructural analysis of SV40 chromatin. Cold Spring Harb Symp Quant Biol (1978) 1.66

Immunological localization of a major karyoskeletal protein in nucleoli of oocytes and somatic cells of Xenopus laevis. J Cell Biol (1982) 1.66

Purification of recombinant adeno-associated virus by iodixanol gradient ultracentrifugation allows rapid and reproducible preparation of vector stocks for gene transfer in the nervous system. Hum Gene Ther (1999) 1.64

Soluble acidic complexes containing histones H3 and H4 in nuclei of Xenopus laevis oocytes. Cell (1982) 1.60

Structural features of the 26 S proteasome complex. J Mol Biol (1993) 1.54

Electron cryo-microscopy and image reconstruction of adeno-associated virus type 2 empty capsids. EMBO Rep (2001) 1.53

Fas ligand expression in the germinal centre. J Pathol (1999) 1.46

Structural organization of the hepatitis B virus minichromosome. J Mol Biol (2001) 1.45

In vitro experimental infection of primary human hepatocytes with hepatitis B virus. Gastroenterology (1994) 1.42

Nucleosome assembly in vitro: separate histone transfer and synergistic interaction of native histone complexes purified from nuclei of Xenopus laevis oocytes. EMBO J (1990) 1.41

Identification of a widespread nuclear actin binding protein. Nature (1989) 1.38

Comparison of different rearranged immunoglobulin kappa genes of a myeloma by electronmicroscopy and restriction mapping of cloned DNA: implications for "allelic exclusion". Nucleic Acids Res (1980) 1.31

Differences of supranucleosomal organization in different kinds of chromatin: cell type-specific globular subunits containing different numbers of nucleosomes. J Cell Biol (1984) 1.31

c-MYC activation in primary and metastatic ductal adenocarcinoma of the pancreas: incidence, mechanisms, and clinical significance. Mod Pathol (2002) 1.31

Genetic heterogeneity of hepatocellular carcinoma. Proc Natl Acad Sci U S A (1994) 1.28

Control of adeno-associated virus type 2 cap gene expression: relative influence of helper virus, terminal repeats, and Rep proteins. J Virol (1997) 1.28

Isolation and characterization of the rat tryptophan oxygenase gene. EMBO J (1982) 1.26

To 'B' or not to 'B' a germinal center? Immunol Today (1997) 1.24

Argyrophilic nuclear and nucleolar proteins of Xenopus laevis oocytes identified by gel electrophoresis. Exp Cell Res (1982) 1.24

The assembly-activating protein promotes capsid assembly of different adeno-associated virus serotypes. J Virol (2011) 1.23

An evolutionarily conserved positively charged amino acid in the putative membrane-spanning domain of the foamy virus envelope protein controls fusion activity. J Virol (2000) 1.23

Mutations in the carboxy terminus of adeno-associated virus 2 capsid proteins affect viral infectivity: lack of an RGD integrin-binding motif. J Gen Virol (1994) 1.23

Cardio-specific long-term gene expression in a porcine model after selective pressure-regulated retroinfusion of adeno-associated viral (AAV) vectors. Gene Ther (2007) 1.23

Adeno-associated virus type 2-mediated inhibition of human immunodeficiency virus type 1 (HIV-1) replication: involvement of p78rep/p68rep and the HIV-1 long terminal repeat. J Gen Virol (1992) 1.22

Identification of frequent chromosomal aberrations in ductal adenocarcinoma of the pancreas by comparative genomic hybridization (CGH). J Pathol (2000) 1.21

Receptor recognition by a hepatitis B virus reveals a novel mode of high affinity virus-receptor interaction. EMBO J (2000) 1.20

Adeno-associated virus type 2 protein interactions: formation of pre-encapsidation complexes. J Virol (1999) 1.20

Precore-mediated inhibition of hepatitis B virus progeny DNA synthesis. J Virol (1993) 1.18

Nuclear membranes and plasma membranes from hen erythrocytes. I. Isolation, characterization, and comparison. J Biol Chem (1971) 1.17

Synthesis and packaging of herpes simplex virus DNA in the course of virus passages at high multiplicity. Intervirology (1978) 1.16

The higher order repeat structure of chromatin is built up of globular particles containing eight nucleosomes. Exp Cell Res (1978) 1.15

A nucleolar skeleton of protein filaments demonstrated in amplified nucleoli of Xenopus laevis. J Cell Biol (1981) 1.15

The 22 S cylinder particles of Xenopus laevis. I. Biochemical and electron microscopic characterization. Eur J Cell Biol (1983) 1.15

The cell surface receptor is a major determinant restricting the host range of the B-lymphotropic papovavirus. J Virol (1993) 1.14

Membrane-to-membrane cross-bridges. A means to orientation and interaction of membrane faces. J Cell Biol (1971) 1.14

The adeno-associated virus type 2 regulatory proteins rep78 and rep68 interact with the transcriptional coactivator PC4. J Virol (1999) 1.14

Hepatitis B virus genome is organized into nucleosomes in the nucleus of the infected cell. Virus Genes (1994) 1.13

Genetic modifications of the adeno-associated virus type 2 capsid reduce the affinity and the neutralizing effects of human serum antibodies. Gene Ther (2003) 1.12

Assembly of adeno-associated virus type 2 capsids in vitro. J Gen Virol (1997) 1.11

The nuclear envelope in freeze-etching. Ergeb Anat Entwicklungsgesch (1971) 1.11

Infection of primary cells by adeno-associated virus type 2 results in a modulation of cell cycle-regulating proteins. J Virol (1997) 1.10

Progress in adeno-associated virus type 2 vector production: promises and prospects for clinical use. Hum Gene Ther (1999) 1.10

Characterization of sequence elements involved in p53 stability regulation reveals cell type dependence for p53 degradation. Oncogene (1998) 1.09

Heterogeneity of spacer lengths in circles of amplified ribosomal DNA of two insect species, Dytiscus marginalis and Acheta domesticus. J Mol Biol (1976) 1.08

Granzyme B is expressed in mouse mast cells in vivo and in vitro and causes delayed cell death independent of perforin. Cell Death Differ (2007) 1.08

High-level expression of adeno-associated virus (AAV) Rep78 or Rep68 protein is sufficient for infectious-particle formation by a rep-negative AAV mutant. J Virol (1995) 1.07

High mobility group proteins of amphibian oocytes: a large storage pool of a soluble high mobility group-1-like protein and involvement in transcriptional events. J Cell Biol (1983) 1.06

p53 overexpression is frequent in European hepatocellular carcinoma and largely independent of the codon 249 hot spot mutation. Oncogene (1994) 1.06

Novel random peptide libraries displayed on AAV serotype 9 for selection of endothelial cell-directed gene transfer vectors. Gene Ther (2011) 1.05

Early phase in the infection of cultured cells with papillomavirus virions. Virology (1995) 1.05

Heart-targeted adeno-associated viral vectors selected by in vivo biopanning of a random viral display peptide library. Gene Ther (2010) 1.05

The 22 S cylinder particles of Xenopus laevis. II. Immunological characterization and localization of their proteins in tissues and cultured cells. Eur J Cell Biol (1983) 1.03

Origin of adeno-associated virus DNA replication is a target of carcinogen-inducible DNA amplification. J Virol (1991) 1.03

Replication of hepatitis B virus in a hepatocellular carcinoma. Virology (1990) 1.03

Transfer of endoplasmic reticulum and Golgi retention signals to human immunodeficiency virus type 1 gp160 inhibits intracellular transport and proteolytic processing of viral glycoprotein but does not influence the cellular site of virus particle budding. J Gen Virol (1997) 1.01

Characterization of bovine keratin genes: similarities of exon patterns in genes coding for different keratins. EMBO J (1984) 1.01

The mechanism of the antiherpetic activity of zinc sulphate. J Gen Virol (1990) 1.01

Cell lines inducibly expressing the adeno-associated virus (AAV) rep gene: requirements for productive replication of rep-negative AAV mutants. J Virol (1994) 0.99

Transcription patterns of amplified Dytiscus genes coding for ribosomal RNA after injection into Xenopus oocyte nuclei. Proc Natl Acad Sci U S A (1978) 0.99

The glutamine synthetase from Azotobacter vinelandii: purification, characterization, regulation and localization. Eur J Biochem (1978) 0.99

Isolation, characterization and chromosomal mapping of the mouse tyrosine aminotransferase gene. J Mol Biol (1985) 0.99

Isolation and characterization of nuclei from bird erythrocytes. Exp Cell Res (1969) 0.97

Characterization and localization of the RNA synthesized in mature avian erythrocytes. Exp Cell Res (1975) 0.97

Immune response to human papillomavirus 16 L1E7 chimeric virus-like particles: induction of cytotoxic T cells and specific tumor protection. Int J Cancer (1999) 0.97