Published in J Virol on December 01, 1980
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Prevalence of antibodies in human sera against JC virus, an isolate from a case of progressive multifocal leukoencephalopathy. J Infect Dis (1973) 4.48
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Persistent BK papovavirus infection of transformed human fetal brain cells. I. Episomal viral DNA in cloned lines deficient in T-antigen expression. J Virol (1979) 1.50
Differential neurooncogenicity of strains of JC virus, a human polyoma virus, in newborn Syrian hamsters. Cancer Res (1977) 1.43
Transformation of primary hamster brain cells with JC virus and its DNA. J Virol (1980) 1.36
The colinear alignment of the genomes of papovaviruses JC, BK, and SV40. Virology (1979) 1.32
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Infectivity of the DNA from four isolates of JC virus. J Virol (1979) 1.27
Restriction endonuclease cleavage map of the DNA of JC virus. J Virol (1979) 1.19
Characterization of JC papovavirus adapted to growth in human embryonic kidney cells. J Virol (1980) 1.17
Polyoma virus in urine during pregnancy. Lancet (1977) 1.14
Transformation of human embryonic kidney cells by human papovarirus BK. J Virol (1979) 1.09
Experimental pineocytoma of the Syrian hamster induced by a human papovavirus (JC). A light and electron microscopic study. Acta Neuropathol (1976) 0.86
The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53. Cell (1990) 20.60
The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product. Science (1989) 16.54
Association of human papillomavirus types 16 and 18 E6 proteins with p53. Science (1990) 12.88
The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53. Cell (1993) 12.41
Mouse cells transformed by bovine papillomavirus contain only extrachromosomal viral DNA sequences. Proc Natl Acad Sci U S A (1981) 9.27
The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes. J Virol (1989) 8.68
Complex formation of human papillomavirus E7 proteins with the retinoblastoma tumor suppressor gene product. EMBO J (1989) 7.69
Transactivation of a bovine papilloma virus transcriptional regulatory element by the E2 gene product. Cell (1985) 7.56
Generation of helper-free amphotropic retroviruses that transduce a dominant-acting, methotrexate-resistant dihydrofolate reductase gene. Mol Cell Biol (1985) 7.49
The primary structure and genetic organization of the bovine papillomavirus type 1 genome. Nature (1982) 7.24
Virus infection induces the assembly of coordinately activated transcription factors on the IFN-beta enhancer in vivo. Mol Cell (1998) 7.01
Bovine papillomavirus contains multiple transforming genes. Proc Natl Acad Sci U S A (1985) 6.73
In vitro tumorigenic transformation by a defined sub-genomic fragment of bovine papilloma virus DNA. Nature (1980) 6.67
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Presence and expression of human papillomavirus sequences in human cervical carcinoma cell lines. Am J Pathol (1985) 6.18
A transcriptional repressor encoded by BPV-1 shares a common carboxy-terminal domain with the E2 transactivator. Cell (1987) 5.75
New type of POU domain in germ line-specific protein Oct-4. Nature (1990) 5.65
A cellular protein mediates association of p53 with the E6 oncoprotein of human papillomavirus types 16 or 18. EMBO J (1991) 5.39
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A rapid method for detecting and mapping homology between heterologous DNAs. Evaluation of polyomavirus genomes. J Biol Chem (1979) 5.32
The state of the p53 and retinoblastoma genes in human cervical carcinoma cell lines. Proc Natl Acad Sci U S A (1991) 5.31
Transformation and replication in mouse cells of a bovine papillomavirus--pML2 plasmid vector that can be rescued in bacteria. Proc Natl Acad Sci U S A (1982) 5.22
Enhancement of cellular src gene product associated tyrosyl kinase activity following polyoma virus infection and transformation. Cell (1984) 5.05
Trans-activation of the human immunodeficiency virus long terminal repeat sequence by DNA viruses. Proc Natl Acad Sci U S A (1986) 4.89
Localization and analysis of bovine papillomavirus type 1 transforming functions. J Virol (1984) 4.77
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The Pax4 gene is essential for differentiation of insulin-producing beta cells in the mammalian pancreas. Nature (1997) 4.69
Pax6 is required for differentiation of glucagon-producing alpha-cells in mouse pancreas. Nature (1997) 4.58
Virus-specific transcription in bovine papillomavirus-transformed mouse cells. Virology (1982) 4.52
Adenovirus E1A, simian virus 40 tumor antigen, and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the retinoblastoma gene product. Proc Natl Acad Sci U S A (1992) 4.27
Structure of an E6AP-UbcH7 complex: insights into ubiquitination by the E2-E3 enzyme cascade. Science (1999) 4.21
Human papillomavirus 16 E6 oncoprotein binds to interferon regulatory factor-3 and inhibits its transcriptional activity. Genes Dev (1998) 4.06
Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53. Mol Cell Biol (1993) 4.04
Molecular cloning of the Harvey sarcoma virus closed circular DNA intermediates: initial structural and biological characterization. J Virol (1979) 3.90
Differential promoter utilization by the bovine papillomavirus in transformed cells and productively infected wart tissues. EMBO J (1987) 3.77
Beta 2-microglobulin expression in human embryonal neuroblastoma reflects its developmental regulation. Cancer Res (1990) 3.75
Bovine papillomavirus transcriptional regulation: localization of the E2-responsive elements of the long control region. J Virol (1987) 3.66
Dissociation of transforming and trans-activation functions for bovine papillomavirus type 1. Nature (1986) 3.63
TGF-beta 1 inhibition of c-myc transcription and growth in keratinocytes is abrogated by viral transforming proteins with pRB binding domains. Cell (1990) 3.55
Decreased expression of N-myc precedes retinoic acid-induced morphological differentiation of human neuroblastoma. Nature (1985) 3.50
In vivo ubiquitination and proteasome-mediated degradation of p53(1). Cancer Res (1996) 3.50
The hPLIC proteins may provide a link between the ubiquitination machinery and the proteasome. Mol Cell (2000) 3.39
Cloning of human papilloma virus genomic DNAs and analysis of homologous polynucleotide sequences. J Virol (1980) 3.34
p300/MDM2 complexes participate in MDM2-mediated p53 degradation. Mol Cell (1998) 3.27
The papillomavirus E2 regulatory proteins. J Biol Chem (1991) 3.27
Transcriptional trans-activation by the human papillomavirus type 16 E2 gene product. J Virol (1987) 3.24
The carboxy-terminal domain shared by the bovine papillomavirus E2 transactivator and repressor proteins contains a specific DNA binding activity. EMBO J (1988) 3.20
E2 polypeptides encoded by bovine papillomavirus type 1 form dimers through the common carboxyl-terminal domain: transactivation is mediated by the conserved amino-terminal domain. Proc Natl Acad Sci U S A (1989) 3.18
Molecular cloning of polyoma virus DNA in Escherichia coli: lambda phage vector system. Science (1979) 3.17
Ubiquitination and degradation of the substrate recognition subunits of SCF ubiquitin-protein ligases. Mol Cell (1998) 3.12
Identification of a human ubiquitin-conjugating enzyme that mediates the E6-AP-dependent ubiquitination of p53. Proc Natl Acad Sci U S A (1994) 3.12
A multigene family encoding several "finger" structures is present and differentially active in mammalian genomes. Cell (1987) 3.09
Prox1 function is crucial for mouse lens-fibre elongation. Nat Genet (1999) 3.01
The transcriptional transactivation function of wild-type p53 is inhibited by SV40 large T-antigen and by HPV-16 E6 oncoprotein. EMBO J (1992) 2.97
Localization of the E6-AP regions that direct human papillomavirus E6 binding, association with p53, and ubiquitination of associated proteins. Mol Cell Biol (1993) 2.91
Mutational analysis of cis elements involved in E2 modulation of human papillomavirus type 16 P97 and type 18 P105 promoters. J Virol (1990) 2.90
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Human papovavirus, BK strain: biological studies including antigenic relationship to simian virus 40. J Virol (1973) 2.54
The helix-loop-helix protein Id-2 enhances cell proliferation and binds to the retinoblastoma protein. Genes Dev (1994) 2.47
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Ubiquitination of p53 and p21 is differentially affected by ionizing and UV radiation. Mol Cell Biol (1997) 2.41
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Characterization of polyoma viral DNA sequences in polyoma-induced hamster tumor cell lines. J Biol Chem (1980) 2.33
Disruption of either the E1 or the E2 regulatory gene of human papillomavirus type 16 increases viral immortalization capacity. Proc Natl Acad Sci U S A (1992) 2.30
Inhibition of cyclin D-CDK4/CDK6 activity is associated with an E2F-mediated induction of cyclin kinase inhibitor activity. Proc Natl Acad Sci U S A (1996) 2.30
The functional BPV-1 E2 trans-activating protein can act as a repressor by preventing formation of the initiation complex. Genes Dev (1991) 2.24
Structure-function analysis of the human papillomavirus type 16 E7 oncoprotein. J Virol (1992) 2.24
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A stable bovine papillomavirus hybrid plasmid that expresses a dominant selective trait. Mol Cell Biol (1983) 2.21
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Efficiency of binding the retinoblastoma protein correlates with the transforming capacity of the E7 oncoproteins of the human papillomaviruses. Proc Natl Acad Sci U S A (1992) 2.10
The role of E6AP in the regulation of p53 protein levels in human papillomavirus (HPV)-positive and HPV-negative cells. J Biol Chem (1998) 2.07
Chronic estrogen-induced cervical and vaginal squamous carcinogenesis in human papillomavirus type 16 transgenic mice. Proc Natl Acad Sci U S A (1996) 2.06