Published in Genetics on November 23, 2010
Microarray comparison of anterior and posterior Drosophila wing imaginal disc cells identifies novel wing genes. G3 (Bethesda) (2013) 0.78
The wavy Mutation Maps to the Inositol 1,4,5-Trisphosphate 3-Kinase 2 (IP3K2) Gene of Drosophila and Interacts with IP3R to Affect Wing Development. G3 (Bethesda) (2015) 0.75
The E3 ubiquitin ligase Nedd4/Nedd4L is directly regulated by microRNA 1. Development (2017) 0.75
An Evolutionarily Conserved Role of Presenilin in Neuronal Protection in the Aging Drosophila Brain. Genetics (2017) 0.75
Sonic hedgehog regulates the growth and patterning of the cerebellum. Development (1999) 4.78
Presenilin is required for activity and nuclear access of Notch in Drosophila. Nature (1999) 4.64
Notch signaling: the core pathway and its posttranslational regulation. Dev Cell (2009) 4.49
Proteolysis that is inhibited by hedgehog targets Cubitus interruptus protein to the nucleus and converts it to a repressor. Cell (1997) 4.43
Direct and long-range action of a DPP morphogen gradient. Cell (1996) 4.33
Dual roles for patched in sequestering and transducing Hedgehog. Cell (1996) 4.10
Molecular interactions between the protein products of the neurogenic loci Notch and Delta, two EGF-homologous genes in Drosophila. Cell (1990) 4.07
Two distinct mechanisms for long-range patterning by Decapentaplegic in the Drosophila wing. Nature (1996) 3.81
Compartment boundaries and the control of Drosophila limb pattern by hedgehog protein. Nature (1994) 3.72
Purkinje-cell-derived Sonic hedgehog regulates granule neuron precursor cell proliferation in the developing mouse cerebellum. Curr Biol (1999) 3.55
The SmoA1 mouse model reveals that notch signaling is critical for the growth and survival of sonic hedgehog-induced medulloblastomas. Cancer Res (2004) 3.33
Hedgehog elicits signal transduction by means of a large complex containing the kinesin-related protein costal2. Cell (1997) 3.06
Neurogenic phenotypes and altered Notch processing in Drosophila Presenilin mutants. Nature (1999) 2.99
Hedgehog is a signaling protein with a key role in patterning Drosophila imaginal discs. Cell (1994) 2.94
A model Notch response element detects Suppressor of Hairless-dependent molecular switch. Curr Biol (2001) 2.65
Closely related transcripts encoded by the neurogenic gene complex enhancer of split of Drosophila melanogaster. EMBO J (1989) 2.54
Sequential organizing activities of engrailed, hedgehog and decapentaplegic in the Drosophila wing. Development (1995) 2.38
Serrate signals through Notch to establish a Wingless-dependent organizer at the dorsal/ventral compartment boundary of the Drosophila wing. Development (1995) 2.36
The Drosophila cubitus interruptus protein and its role in the wingless and hedgehog signal transduction pathways. Mech Dev (1995) 2.25
Hedgehog creates a gradient of DPP activity in Drosophila wing imaginal discs. Mol Cell (2000) 2.23
Crossing paths with Notch in the hyper-network. Curr Opin Cell Biol (2007) 2.20
Discrete enhancer elements mediate selective responsiveness of enhancer of split complex genes to common transcriptional activators. Dev Biol (1999) 2.07
The Notch signalling pathway is required for Enhancer of split bHLH protein expression during neurogenesis in the Drosophila embryo. Development (1994) 2.07
Complex cellular and subcellular regulation of notch expression during embryonic and imaginal development of Drosophila: implications for notch function. J Cell Biol (1991) 2.05
Cell proliferation control by Notch signaling in Drosophila development. Development (1998) 1.98
A Hedgehog activity gradient contributes to AP axial patterning of the Drosophila wing. Development (1997) 1.88
Seven genes of the Enhancer of split complex of Drosophila melanogaster encode helix-loop-helix proteins. Genetics (1992) 1.87
Delta is a ventral to dorsal signal complementary to Serrate, another Notch ligand, in Drosophila wing formation. Genes Dev (1996) 1.82
The Enhancer of split [E(spl)] locus of Drosophila encodes seven independent helix-loop-helix proteins. Proc Natl Acad Sci U S A (1992) 1.76
Functional relationships between Notch, Su(H) and the bHLH genes of the E(spl) complex: the E(spl) genes mediate only a subset of Notch activities during imaginal development. Development (1996) 1.75
Feedback regulation is central to Delta-Notch signalling required for Drosophila wing vein morphogenesis. Development (1997) 1.74
Changing spatial patterns of DNA replication in the developing wing of Drosophila. Dev Biol (1987) 1.73
Regulation of notch endosomal sorting and signaling by Drosophila Nedd4 family proteins. Curr Biol (2004) 1.68
Notch signalling regulates veinlet expression and establishes boundaries between veins and interveins in the Drosophila wing. Development (1997) 1.68
Notch regulates wingless expression and is not required for reception of the paracrine wingless signal during wing margin neurogenesis in Drosophila. Development (1995) 1.61
Creating a Drosophila wing de novo, the role of engrailed, and the compartment border hypothesis. Development (1995) 1.59
Mechanism and evolution of cytosolic Hedgehog signal transduction. Development (2010) 1.58
Temperature-sensitive periods and autonomy of pleiotropic effects of l(1)Nts1, a conditional notch lethal in Drosophila. Dev Biol (1978) 1.56
A double-assurance mechanism controls cell cycle exit upon terminal differentiation in Drosophila. Dev Cell (2007) 1.55
Vein is a novel component in the Drosophila epidermal growth factor receptor pathway with similarity to the neuregulins. Genes Dev (1996) 1.53
Roles of the Notch gene in Drosophila wing morphogenesis. Mech Dev (1994) 1.53
Pattern formation in the Drosophila wing: The development of the veins. Bioessays (2003) 1.51
Direct downstream targets of proneural activators in the imaginal disc include genes involved in lateral inhibitory signaling. Genes Dev (1994) 1.49
Two genetically and molecularly distinct functions involved in early neurogenesis reside within the Enhancer of split locus of Drosophila melanogaster. Genetics (1991) 1.47
An intrinsic dominant negative activity of serrate that is modulated during wing development in Drosophila. Dev Biol (1997) 1.42
The Abruptex domain of Notch regulates negative interactions between Notch, its ligands and Fringe. Development (2000) 1.41
Lateral inhibition in proneural clusters: cis-regulatory logic and default repression by Suppressor of Hairless. Development (2005) 1.41
The COE transcription factor Collier is a mediator of short-range Hedgehog-induced patterning of the Drosophila wing. Curr Biol (1999) 1.39
The Serrate locus of Drosophila and its role in morphogenesis of the wing imaginal discs: control of cell proliferation. Development (1994) 1.39
Notch signaling directly controls cell proliferation in the Drosophila wing disc. Proc Natl Acad Sci U S A (2000) 1.38
The Enhancer of split complex and adjacent genes in the 96F region of Drosophila melanogaster are required for segregation of neural and epidermal progenitor cells. Genetics (1992) 1.32
Implications of dynamic patterns of Delta and Notch expression for cellular interactions during Drosophila development. Development (1993) 1.26
In vivo functions of the patched protein: requirement of the C terminus for target gene inactivation but not Hedgehog sequestration. Mol Cell (2000) 1.25
PP4 and PP2A regulate Hedgehog signaling by controlling Smo and Ci phosphorylation. Development (2008) 1.23
Long-range Dpp signaling is regulated to restrict BMP signaling to a crossvein competent zone. Dev Biol (2005) 1.21
Subcellular localization of the segment polarity protein patched suggests an interaction with the wingless reception complex in Drosophila embryos. Development (1994) 1.21
Pax9 and Jagged1 act downstream of Gli3 in vertebrate limb development. Mech Dev (2005) 1.20
Structural requirements for notch signalling with delta and serrate during the development and patterning of the wing disc of Drosophila. Development (2000) 1.17
Boundaries in the Drosophila wing imaginal disc organize vein-specific genetic programs. Development (1998) 1.17
Ectopic expression of individual E(spl) genes has differential effects on different cell fate decisions and underscores the biphasic requirement for notch activity in wing margin establishment in Drosophila. Development (1999) 1.16
Genetic characterization of the Drosophila melanogaster Suppressor of deltex gene: A regulator of notch signaling. Genetics (1998) 1.12
Sonic hedgehog-responsive genes in the fetal prostate. J Biol Chem (2008) 1.11
Hedgehog activity, independent of decapentaplegic, participates in wing disc patterning. Development (1997) 1.10
groucho and hedgehog regulate engrailed expression in the anterior compartment of the Drosophila wing. Development (1995) 1.08
The Enhancer of split complex of Drosophila melanogaster harbors three classes of Notch responsive genes. Mech Dev (1999) 1.07
Expression of Notch and Wnt pathway components and activation of Notch signaling in medulloblastomas from heterozygous patched mice. J Neurooncol (2006) 1.05
Su(H)-independent activity of hairless during mechano-sensory organ formation in Drosophila. Mech Dev (2000) 1.02
Tissue-specific regulation of vein/EGF receptor signaling in Drosophila. Dev Biol (1999) 0.97
Impaired cerebellar functions in mutant mice lacking DNER. Mol Cell Neurosci (2005) 0.97
Notch and Wingless modulate the response of cells to Hedgehog signalling in the Drosophila wing. Dev Biol (2002) 0.95
The pleiotropic function of Delta during postembryonic development of Drosophila melanogaster. Genetics (1993) 0.91
Hedgehog activates the EGF receptor pathway during Drosophila head development. Development (1999) 0.90
Functional analysis of genes differentially expressed in the Drosophila wing disc: role of transcripts enriched in the wing region. Genetics (2006) 0.88
A screen for modifiers of hedgehog signaling in Drosophila melanogaster identifies swm and mts. Genetics (2008) 0.86
Role of knot (kn) in wing patterning in Drosophila. Genetics (1997) 0.82
Vein-positioning in the Drosophila wing in response to Hh; new roles of Notch signaling. Mech Dev (2003) 0.82
A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable. Nature (2011) 5.45
Specificity of Drosophila cytonemes for distinct signaling pathways. Science (2011) 2.60
Dependence of Drosophila wing imaginal disc cytonemes on Decapentaplegic. Nature (2005) 2.40
FGF is an essential mitogen and chemoattractant for the air sacs of the drosophila tracheal system. Dev Cell (2002) 2.13
Cytoneme-mediated contact-dependent transport of the Drosophila decapentaplegic signaling protein. Science (2014) 1.92
Expression profiling of Drosophila imaginal discs. Genome Biol (2002) 1.50
Regulation of cellular plasticity in Drosophila imaginal disc cells by the Polycomb group, trithorax group and lama genes. Development (2005) 1.37
The C-terminal tail of the Hedgehog receptor Patched regulates both localization and turnover. Genes Dev (2006) 1.32
Generalizing moving averages for tiling arrays using combined p-value statistics. Stat Appl Genet Mol Biol (2010) 1.16
brinker and optomotor-blind act coordinately to initiate development of the L5 wing vein primordium in Drosophila. Development (2004) 1.13
Regulation of tooth number by fine-tuning levels of receptor-tyrosine kinase signaling. Development (2011) 1.08
Regulation of Drosophila matrix metalloprotease Mmp2 is essential for wing imaginal disc:trachea association and air sac tubulogenesis. Dev Biol (2009) 1.03
Drosophila signal peptide peptidase is an essential protease for larval development. Genetics (2005) 1.01
Tracheal branch repopulation precedes induction of the Drosophila dorsal air sac primordium. Dev Biol (2005) 1.01
Hedgehog targets in the Drosophila embryo and the mechanisms that generate tissue-specific outputs of Hedgehog signaling. Development (2010) 1.01
An essential role for zygotic expression in the pre-cellular Drosophila embryo. PLoS Genet (2013) 1.00
Organ renewal and cell divisions by differentiated cells in Drosophila. Proc Natl Acad Sci U S A (2008) 0.96
Smoothened regulates activator and repressor functions of Hedgehog signaling via two distinct mechanisms. J Biol Chem (2006) 0.96
From molecules to mastication: the development and evolution of teeth. Wiley Interdiscip Rev Dev Biol (2012) 0.92
Characterization of dental epithelial stem cells from the mouse incisor with two-dimensional and three-dimensional platforms. Tissue Eng Part C Methods (2012) 0.90
Two patched protein subtypes and a conserved domain of group I proteins that regulates turnover. J Biol Chem (2008) 0.89
A screen for modifiers of hedgehog signaling in Drosophila melanogaster identifies swm and mts. Genetics (2008) 0.86
Cysteine repeat domains and adjacent sequences determine distinct bone morphogenetic protein modulatory activities of the Drosophila Sog protein. Genetics (2004) 0.85
BCL11B regulates epithelial proliferation and asymmetric development of the mouse mandibular incisor. PLoS One (2012) 0.83
Linear RNA amplification for the production of microarray hybridization probes. Methods Mol Biol (2008) 0.82
The chromatin-remodeling protein Osa interacts with CyclinE in Drosophila eye imaginal discs. Genetics (2009) 0.80
Paracrine signaling mediated at cell-cell contacts. Bioessays (2014) 0.80
Direct delivery mechanisms of morphogen dispersion. Sci Signal (2011) 0.78
Microarray comparison of anterior and posterior Drosophila wing imaginal disc cells identifies novel wing genes. G3 (Bethesda) (2013) 0.78
A graphical model method for integrating multiple sources of genome-scale data. Stat Appl Genet Mol Biol (2013) 0.78
Expression and characterization of Drosophila signal peptide peptidase-like (sppL), a gene that encodes an intramembrane protease. PLoS One (2012) 0.76
Correction: Bicoid gradient formation and function in the Drosophila pre-syncytial blastoderm. Elife (2017) 0.75