Published in J Biol Chem on September 25, 1993
Nuclear localization signals overlap DNA- or RNA-binding domains in nucleic acid-binding proteins. Nucleic Acids Res (1995) 2.52
Splinkerettes--improved vectorettes for greater efficiency in PCR walking. Nucleic Acids Res (1995) 2.51
The Saccharomyces cerevisiae ETH1 gene, an inducible homolog of exonuclease III that provides resistance to DNA-damaging agents and limits spontaneous mutagenesis. Mol Cell Biol (1999) 1.23
DNA repair mechanisms and the bypass of DNA damage in Saccharomyces cerevisiae. Genetics (2013) 1.17
Pir1p mediates translocation of the yeast Apn1p endonuclease into the mitochondria to maintain genomic stability. Mol Cell Biol (2001) 1.14
Distinct roles of Ape1 protein in the repair of DNA damage induced by ionizing radiation or bleomycin. J Biol Chem (2010) 1.06
Trans-complementation by human apurinic endonuclease (Ape) of hypersensitivity to DNA damage and spontaneous mutator phenotype in apn1-yeast. Nucleic Acids Res (1995) 0.94
The current state of eukaryotic DNA base damage and repair. Nucleic Acids Res (2015) 0.89
ATF4-dependent oxidative induction of the DNA repair enzyme Ape1 counteracts arsenite cytotoxicity and suppresses arsenite-mediated mutagenesis. Mol Cell Biol (2007) 0.88
A novel Nudix hydrolase for oxidized purine nucleoside triphosphates encoded by ORFYLR151c (PCD1 gene) in Saccharomyces cerevisiae. Nucleic Acids Res (2004) 0.85
Evidence that msh1p plays multiple roles in mitochondrial base excision repair. Genetics (2009) 0.82
Disruption of the Saccharomyces cerevisiae cell-wall pathway gene SLG1 causes hypersensitivity to the antitumor drug bleomycin. Mol Genet Genomics (2003) 0.82
Yeast apurinic/apyrimidinic endonuclease Apn1 protects mammalian neuronal cell line from oxidative stress. J Neurochem (2007) 0.81
Saccharomyces cerevisiae Apn1 mutation affecting stable protein expression mimics catalytic activity impairment: implications for assessing DNA repair capacity in humans. DNA Repair (Amst) (2012) 0.76
Resolution of recent evolutionary divergence among Escherichia coli from related lineages: the application of pulsed field electrophoresis to molecular epidemiology. J Infect Dis (1990) 8.33
Positive control of a global antioxidant defense regulon activated by superoxide-generating agents in Escherichia coli. Proc Natl Acad Sci U S A (1990) 6.05
Adjunctive subconjunctival mitomycin C in glaucoma triple procedure. Ophthalmology (1995) 5.35
The Arabidopsis thaliana salt tolerance gene SOS1 encodes a putative Na+/H+ antiporter. Proc Natl Acad Sci U S A (2000) 5.08
Molecular characterization of the soxRS genes of Escherichia coli: two genes control a superoxide stress regulon. Nucleic Acids Res (1991) 4.50
Inducible repair of oxidative DNA damage in Escherichia coli. Nature (1983) 4.35
Deficiency of the hematopoietic cell-specific Rho family GTPase Rac2 is characterized by abnormalities in neutrophil function and host defense. Immunity (1999) 3.84
Role of the acrAB locus in organic solvent tolerance mediated by expression of marA, soxS, or robA in Escherichia coli. J Bacteriol (1997) 3.81
Activation of oxidative stress genes by mutations at the soxQ/cfxB/marA locus of Escherichia coli. J Bacteriol (1991) 3.75
Exonuclease III and endonuclease IV remove 3' blocks from DNA synthesis primers in H2O2-damaged Escherichia coli. Proc Natl Acad Sci U S A (1986) 3.72
DNA N-glycosylases and UV repair. Nature (1980) 3.69
Escherichia coli xth mutants are hypersensitive to hydrogen peroxide. J Bacteriol (1983) 3.69
Rare structural variants found in attention-deficit hyperactivity disorder are preferentially associated with neurodevelopmental genes. Mol Psychiatry (2009) 3.56
Role of beta gamma subunits of G proteins in targeting the beta-adrenergic receptor kinase to membrane-bound receptors. Science (1992) 3.45
A global response induced in Escherichia coli by redox-cycling agents overlaps with that induced by peroxide stress. J Bacteriol (1989) 3.38
Genome-wide transcriptional profiling of the Escherichia coli responses to superoxide stress and sodium salicylate. J Bacteriol (2001) 3.28
Concentrated ambient air particles induce mild pulmonary inflammation in healthy human volunteers. Am J Respir Crit Care Med (2000) 3.25
T-DNA insertional mutagenesis for functional genomics in rice. Plant J (2000) 3.25
Homogeneous Escherichia coli endonuclease IV. Characterization of an enzyme that recognizes oxidative damage in DNA. J Biol Chem (1988) 3.15
Repressor mutations in the marRAB operon that activate oxidative stress genes and multiple antibiotic resistance in Escherichia coli. J Bacteriol (1994) 3.13
Two-stage control of an oxidative stress regulon: the Escherichia coli SoxR protein triggers redox-inducible expression of the soxS regulatory gene. J Bacteriol (1992) 3.06
Active site and complete sequence of the suicidal methyltransferase that counters alkylation mutagenesis. Proc Natl Acad Sci U S A (1985) 3.01
Construction of an Escherichia coli K-12 ada deletion by gene replacement in a recD strain reveals a second methyltransferase that repairs alkylated DNA. J Bacteriol (1988) 3.01
Anti-human immunodeficiency virus activity and cellular metabolism of a potential prodrug of the acyclic nucleoside phosphonate 9-R-(2-phosphonomethoxypropyl)adenine (PMPA), Bis(isopropyloxymethylcarbonyl)PMPA. Antimicrob Agents Chemother (1998) 3.01
Activation by nitric oxide of an oxidative-stress response that defends Escherichia coli against activated macrophages. Proc Natl Acad Sci U S A (1993) 2.92
Endoplasmic reticulum degradation requires lumen to cytosol signaling. Transmembrane control of Hrd1p by Hrd3p. J Cell Biol (2000) 2.88
Overproduction of peroxide-scavenging enzymes in Escherichia coli suppresses spontaneous mutagenesis and sensitivity to redox-cycling agents in oxyR-mutants. EMBO J (1988) 2.71
An iron-sulfur center essential for transcriptional activation by the redox-sensing SoxR protein. EMBO J (1994) 2.66
Repair of alkylated DNA in Escherichia coli. Physical properties of O6-methylguanine-DNA methyltransferase. J Biol Chem (1982) 2.56
Incision activity of human apurinic endonuclease (Ape) at abasic site analogs in DNA. J Biol Chem (1995) 2.54
Activation of multiple antibiotic resistance and binding of stress-inducible promoters by Escherichia coli Rob protein. J Bacteriol (1995) 2.53
Metabolic sources of hydrogen peroxide in aerobically growing Escherichia coli. J Biol Chem (1995) 2.45
Novel Jeff=1/2 Mott state induced by relativistic spin-orbit coupling in Sr2IrO4. Phys Rev Lett (2008) 2.38
Redox-operated genetic switches: the SoxR and OxyR transcription factors. Trends Biotechnol (2001) 2.38
Posttranscriptional repression of Escherichia coli OmpF protein in response to redox stress: positive control of the micF antisense RNA by the soxRS locus. J Bacteriol (1993) 2.37
Yeast structural gene (APN1) for the major apurinic endonuclease: homology to Escherichia coli endonuclease IV. Proc Natl Acad Sci U S A (1990) 2.35
Marital conflict in older adults: endocrinological and immunological correlates. Psychosom Med (1997) 2.34
Direct nitric oxide signal transduction via nitrosylation of iron-sulfur centers in the SoxR transcription activator. Proc Natl Acad Sci U S A (2000) 2.32
SoxS, an activator of superoxide stress genes in Escherichia coli. Purification and interaction with DNA. J Biol Chem (1994) 2.23
Two distinct human DNA diesterases that hydrolyze 3'-blocking deoxyribose fragments from oxidized DNA. Nucleic Acids Res (1991) 2.22
Optimized THP-1 differentiation is required for the detection of responses to weak stimuli. Inflamm Res (2007) 2.21
Meta-analysis of exercise testing to detect coronary artery disease in women. Am J Cardiol (1999) 2.20
Homeostatic regulation of intracellular hydrogen peroxide concentration in aerobically growing Escherichia coli. J Bacteriol (1997) 2.19
Toward an explanation of the power law artifact: insights from response surface analysis. Mem Cognit (2000) 2.15
Induction of resistance to alkylating agents in E. coli: the ada+ gene product serves both as a regulatory protein and as an enzyme for repair of mutagenic damage. EMBO J (1984) 2.15
Key role for sulfur in peptide metabolism and in regulation of three hydrogenases in the hyperthermophilic archaeon Pyrococcus furiosus. J Bacteriol (2001) 2.12
Evaluation of pulsed-field gel electrophoresis in epidemiological investigations of meningococcal disease outbreaks caused by Neisseria meningitidis serogroup C. J Clin Microbiol (2001) 2.12
Interaction of human apurinic endonuclease and DNA polymerase beta in the base excision repair pathway. Proc Natl Acad Sci U S A (1997) 2.12
Molecular epidemiology of adhesin and hemolysin virulence factors among uropathogenic Escherichia coli. Infect Immun (1989) 2.12
Cellular role of yeast Apn1 apurinic endonuclease/3'-diesterase: repair of oxidative and alkylation DNA damage and control of spontaneous mutation. Mol Cell Biol (1991) 2.11
Dominant negative mutation of the hematopoietic-specific Rho GTPase, Rac2, is associated with a human phagocyte immunodeficiency. Blood (2000) 2.08
Crystal structure of the Escherichia coli Rob transcription factor in complex with DNA. Nat Struct Biol (2000) 2.08
Risk factors for retinal vein occlusions. A case-control study. Ophthalmology (1992) 2.06
Suicide inactivation of the E. coli O6-methylguanine-DNA methyltransferase. EMBO J (1982) 2.03
Restriction fragment length polymorphisms among uropathogenic Escherichia coli isolates: pap-related sequences compared with rrn operons. Infect Immun (1990) 1.95
Glutathione in Escherichia coli is dispensable for resistance to H2O2 and gamma radiation. J Bacteriol (1986) 1.91
Redox signal transduction: mutations shifting [2Fe-2S] centers of the SoxR sensor-regulator to the oxidized form. Cell (1997) 1.88
Rac2 stimulates Akt activation affecting BAD/Bcl-XL expression while mediating survival and actin function in primary mast cells. Immunity (2000) 1.87
Nosocomial clonal dissemination of methicillin-resistant Staphylococcus aureus. Elucidation by plasmid analysis. Arch Intern Med (1987) 1.86
The redox state of the [2Fe-2S] clusters in SoxR protein regulates its activity as a transcription factor. J Biol Chem (1996) 1.75
Analysis of class II (hydrolytic) and class I (beta-lyase) apurinic/apyrimidinic endonucleases with a synthetic DNA substrate. Nucleic Acids Res (1990) 1.75
Primary glaucoma triple procedure with or without adjunctive mitomycin. Prognostic factors for filtration failure. Ophthalmology (1996) 1.67
Transmembrane signalling by a hybrid protein: communication from the domain of chemoreceptor Trg that recognizes sugar-binding proteins to the kinase/phosphatase domain of osmosensor EnvZ. J Bacteriol (1994) 1.66
Site-specific deoxyribonucleases in Bacillus subtilis and other Bacillus strains. J Bacteriol (1976) 1.65
Use of molecular subtyping to document long-term persistence of Corynebacterium diphtheriae in South Dakota. J Clin Microbiol (1999) 1.64
Outbreak of neonatal listeriosis associated with mineral oil. Pediatr Infect Dis J (1991) 1.64
leafy hull sterile1 is a homeotic mutation in a rice MADS box gene affecting rice flower development. Plant Cell (2000) 1.62
5,6-Saturated thymine lesions in DNA: production by ultraviolet light or hydrogen peroxide. Nucleic Acids Res (1982) 1.62
An increased estimate of the merger rate of double neutron stars from observations of a highly relativistic system. Nature (2003) 1.62
Roles of nitric oxide in inducible resistance of Escherichia coli to activated murine macrophages. Infect Immun (1995) 1.60
Detection and identification of mycobacteria by amplification of the internal transcribed spacer regions with genus- and species-specific PCR primers. J Clin Microbiol (2000) 1.60
Crystal structure of a suicidal DNA repair protein: the Ada O6-methylguanine-DNA methyltransferase from E. coli. EMBO J (1994) 1.58
Identification of SoxS-regulated genes in Salmonella enterica serovar typhimurium. J Bacteriol (2000) 1.58
Sequence specificity for DNA binding by Escherichia coli SoxS and Rob proteins. Mol Microbiol (1996) 1.57
Cloning of BRAK, a novel divergent CXC chemokine preferentially expressed in normal versus malignant cells. Biochem Biophys Res Commun (1999) 1.56
Yeast DNA 3'-repair diesterase is the major cellular apurinic/apyrimidinic endonuclease: substrate specificity and kinetics. J Biol Chem (1988) 1.55
Binuclear [2Fe-2S] clusters in the Escherichia coli SoxR protein and role of the metal centers in transcription. J Biol Chem (1995) 1.53
Use of insulin pump therapy at nighttime only for children 7-10 years of age with type 1 diabetes. Diabetes Care (2000) 1.51
Regional deposition and retention of particles in shallow, inhaled boluses: effect of lung volume. J Appl Physiol (1985) (1999) 1.51
Spacing of promoter elements regulates the basal expression of the soxS gene and converts SoxR from a transcriptional activator into a repressor. EMBO J (1997) 1.50
Medical student radiology teaching in Australia and New Zealand. Australas Radiol (2007) 1.46
Abasic site binding by the human apurinic endonuclease, Ape, and determination of the DNA contact sites. Nucleic Acids Res (1997) 1.44
Atracurium and vecuronium block nicotine-induced carotid body chemoreceptor responses. Acta Anaesthesiol Scand (2002) 1.44
Distinguishing optimism from pessimism in older adults: is it more important to be optimistic or not to be pessimistic? J Pers Soc Psychol (1997) 1.44
Primary glaucoma triple procedure in patients with primary open-angle glaucoma: the effect of mitomycin C in patients with and without prognostic factors for filtration failure. Am J Ophthalmol (1998) 1.44
Correlation between evoked motor response of the sciatic nerve and sensory blockade. Anesthesiology (1997) 1.44
Medical therapy or coronary artery bypass graft surgery for chronic stable angina: an update using decision analysis. Am J Med (2001) 1.43
Redox signal transduction via iron-sulfur clusters in the SoxR transcription activator. Trends Biochem Sci (1997) 1.43
Use of spirometry for case finding, diagnosis, and management of chronic obstructive pulmonary disease (COPD). Evid Rep Technol Assess (Summ) (2005) 1.42
Coronary AVE micro stents: serial quantitative angiography and histology in a canine model. Cathet Cardiovasc Diagn (1997) 1.39
Intraocular pressure-dependent retinal vascular change in adult chronic open-angle glaucoma patients. Ophthalmology (1991) 1.39
Milrinone improves lung compliance in patients receiving mechanical ventilation for cardiogenic pulmonary edema. Acta Anaesthesiol Scand (2003) 1.39
Potent intracellular oxidative stress exerted by the carcinogen 4-nitroquinoline-N-oxide. Cancer Res (1993) 1.39
Significance of RRM1 and ERCC1 expression in resectable pancreatic adenocarcinoma. Oncogene (2009) 1.37
In vivo kinetics of a redox-regulated transcriptional switch. Proc Natl Acad Sci U S A (1997) 1.37
Specificity of the mutator caused by deletion of the yeast structural gene (APN1) for the major apurinic endonuclease. Proc Natl Acad Sci U S A (1994) 1.36
Drosophila phosphoinositide-dependent kinase-1 regulates apoptosis and growth via the phosphoinositide 3-kinase-dependent signaling pathway. Proc Natl Acad Sci U S A (2001) 1.35
Yeast DNA diesterase for 3'-fragments of deoxyribose: purification and physical properties of a repair enzyme for oxidative DNA damage. J Biol Chem (1988) 1.34
Anisotropic Dirac fermions in a Bi square net of SrMnBi2. Phys Rev Lett (2011) 1.33
Response to bronchodilator drug administration by a new reservoir aerosol delivery system and a review of other auxiliary delivery systems. Am Rev Respir Dis (1982) 1.33