PubRank

A J Tobin

Author PubWeight™ 92.54‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes. Nature 1993 5.47
2 Two genes encode distinct glutamate decarboxylases. Neuron 1991 3.68
3 Molecular biology of GABAA receptors. FASEB J 1990 2.66
4 Two forms of the gamma-aminobutyric acid synthetic enzyme glutamate decarboxylase have distinct intraneuronal distributions and cofactor interactions. J Neurochem 1991 2.66
5 Modulating autoimmune responses to GAD inhibits disease progression and prolongs islet graft survival in diabetes-prone mice. Nat Med 1996 2.35
6 Comparative localization of two forms of glutamic acid decarboxylase and their mRNAs in rat brain supports the concept of functional differences between the forms. J Neurosci 1994 2.24
7 Carbonic anhydrase from parsley leaves. J Biol Chem 1970 2.03
8 Two human glutamate decarboxylases, 65-kDa GAD and 67-kDa GAD, are each encoded by a single gene. Proc Natl Acad Sci U S A 1992 1.93
9 The structural and functional heterogeneity of glutamic acid decarboxylase: a review. Neurochem Res 1991 1.93
10 Glutamic acid decarboxylase cDNA: nucleotide sequence encoding an enzymatically active fusion protein. J Neurosci 1987 1.78
11 Response of peripheral-blood mononuclear cells to glutamate decarboxylase in insulin-dependent diabetes. Lancet 1992 1.73
12 Autoimmunity to two forms of glutamate decarboxylase in insulin-dependent diabetes mellitus. J Clin Invest 1992 1.67
13 Brain glutamate decarboxylase cloned in lambda gt-11: fusion protein produces gamma-aminobutyric acid. Science 1986 1.60
14 A novel alpha subunit in rat brain GABAA receptors. Neuron 1989 1.51
15 Distribution of developmentally regulated hemoglobins in embryonic erythroid populations. Dev Biol 1979 1.47
16 Different distributions of GAD65 and GAD67 mRNAs suggest that the two glutamate decarboxylases play distinctive functional roles. J Neurosci Res 1993 1.42
17 Comparative localization of mRNAs encoding two forms of glutamic acid decarboxylase with nonradioactive in situ hybridization methods. J Comp Neurol 1993 1.26
18 Increased expression of glutamate decarboxylase (GAD(67)) in feline lumbar spinal cord after complete thoracic spinal cord transection. J Neurosci Res 2000 1.25
19 Chronic intermittent ethanol treatment in rats increases GABA(A) receptor alpha4-subunit expression: possible relevance to alcohol dependence. J Neurochem 1997 1.21
20 Uniqueness and redundancy in GABA production. Perspect Dev Neurobiol 1998 1.20
21 Evaluating the contribution of posttranscriptional processing to differential gene expression. Dev Biol 1979 1.06
22 In situ hybridization to localize mRNA encoding the neurotransmitter synthetic enzyme glutamate decarboxylase in mouse cerebellum. Proc Natl Acad Sci U S A 1986 1.03
23 The exon-intron organization of the genes (GAD1 and GAD2) encoding two human glutamate decarboxylases (GAD67 and GAD65) suggests that they derive from a common ancestral GAD. Genomics 1994 1.02
24 Population structure and residency patterns of the blacktip reef shark Carcharhinus melanopterus in turbid coastal environments. J Fish Biol 2013 1.00
25 Conditionally immortalized cell lines, engineered to produce and release GABA, modulate the development of behavioral seizures. Exp Neurol 2000 1.00
26 Complete amino acid sequences of the major early embryonic alpha-like globins of the chicken. J Biol Chem 1980 0.97
27 Islet cell cytoplasmic autoantibody reactivity to glutamate decarboxylase in insulin-dependent diabetes. J Clin Invest 1993 0.97
28 Postnatal expression of glutamate decarboxylases in developing rat cerebellum. Neurochem Res 1991 0.97
29 4-Aminobutyrate aminotransferase (GABA-transaminase) deficiency. J Inherit Metab Dis 1999 0.97
30 Distinctive patterns of GABAA receptor subunit mRNAs in 13 cell lines. J Neurosci 1994 0.95
31 Differential localization of two glutamic acid decarboxylases (GAD65 and GAD67) in adult monkey visual cortex. J Comp Neurol 1994 0.94
32 Glutamate decarboxylases in nonneural cells of rat testis and oviduct: differential expression of GAD65 and GAD67. J Neurochem 1992 0.94
33 The gamma-aminobutyric acid receptor gamma 3 subunit gene (GABRG3) is tightly linked to the alpha 5 subunit gene (GABRA5) on human chromosome 15q11-q13 and is transcribed in the same orientation. Genomics 1995 0.93
34 Assignment of the rhodopsin gene to human chromosome 3. Invest Ophthalmol Vis Sci 1986 0.92
35 Transient increase in expression of a glutamate decarboxylase (GAD) mRNA during the postnatal development of the rat striatum. Dev Biol 1992 0.91
36 Detection of point mutations associated with genetic diseases by an exon scanning technique. Genomics 1990 0.91
37 Independent cellular and ontogenetic expression of mRNAs encoding three alpha polypeptides of the rat GABAA receptor. Neuroscience 1991 0.90
38 Few transcribed RNAs are translated in avian erythroid cells. Dev Biol 1978 0.89
39 Comparative distribution of mRNAs for glutamic acid decarboxylase, tyrosine hydroxylase, and tachykinins in the basal ganglia: an in situ hybridization study in the rodent brain. J Comp Neurol 1987 0.89
40 Long-term increase of glutamate decarboxylase mRNA in a rat model of temporal lobe epilepsy. Neuron 1990 0.88
41 Hemoglobin synthesis in isolated erythroid colonies from the chick embryo. Dev Biol 1976 0.87
42 A novel method for expression and large-scale production of human brain l-glutamate decarboxylase. Biochem Biophys Res Commun 2000 0.87
43 Comparative distribution of messenger RNAs encoding glutamic acid decarboxylases (Mr 65,000 and Mr 67,000) in the basal ganglia of the rat. J Comp Neurol 1992 0.86
44 Molecular cloning of mammalian 28,000 Mr vitamin D-dependent calcium binding protein (calbindin-D28K): expression of calbindin-D28K RNAs in rodent brain and kidney. DNA 1988 0.86
45 Assignment of the rhodopsin gene to human chromosome three, region 3q21-3q24 by in situ hybridization studies. Curr Eye Res 1986 0.86
46 GABA signalling: therapeutic targets for epilepsy, Parkinson's disease and Huntington's disease. Expert Opin Ther Targets 2001 0.86
47 Immortalized hypothalamic GT1-7 neurons express functional gamma-aminobutyric acid type A receptors. Mol Pharmacol 1992 0.86
48 Parallel increases in striatal glutamic acid decarboxylase activity and mRNA levels in rats with lesions of the nigrostriatal pathway. Brain Res 1990 0.85
49 Cyclic AMP decreases the expression of a neuronal marker (GAD67) and increases the expression of an astroglial marker (GFAP) in C6 cells. J Neurochem 1994 0.85
50 Use of c-fos to identify activity-dependent spinal neurons after stepping in intact adult rats. Spinal Cord 2005 0.85
51 Splicing defect at the ornithine aminotransferase (OAT) locus in gyrate atrophy. Am J Hum Genet 1990 0.83
52 Metabolic compromise with systemic 3-nitropropionic acid produces striatal apoptosis in Sprague-Dawley rats but not in BALB/c ByJ mice. Exp Neurol 1998 0.83
53 Biphasic modulation of GABA(A) receptor binding by steroids suggests functional correlates. Neurochem Res 1999 0.83
54 Isolation and cloning of a voltage-dependent anion channel-like Mr 36,000 polypeptide from mammalian brain. J Biol Chem 1992 0.83
55 Calcium binding protein (calbindin-D28k) and glutamate decarboxylase gene expression after kindling induced seizures. Brain Res Mol Brain Res 1991 0.82
56 Alterations in GABAA receptor alpha 1 and alpha 4 subunit mRNA levels in thalamic relay nuclei following absence-like seizures in rats. Exp Neurol 1998 0.82
57 Cellular distribution of calbindin D28K mRNAs in the adult mouse brain. J Neurosci Res 1994 0.82
58 Multiple elements regulate GAD65 transcription. Dev Neurosci 1997 0.82
59 Two invariant tryptophans on the alpha1 subunit define domains necessary for GABA(A) receptor assembly. J Biol Chem 1999 0.81
60 GABA alters GABAA receptor mRNAs and increases ligand binding. J Neurochem 1993 0.81
61 Beta-adrenergic receptor activation promotes process outgrowth in an embryonic rat basal forebrain cell line and in primary neurons. Eur J Neurosci 1996 0.80
62 Glutamate decarboxylase: an autoantigen in IDDM. Diabetes Care 1992 0.80
63 Glutamate decarboxylases and autoimmunity in insulin-dependent diabetes. Trends Pharmacol Sci 1993 0.80
64 Conditionally-immortalized astrocytic cell line expresses GAD and secretes GABA under tetracycline regulation. J Neurosci Res 2000 0.79
65 Brain implantations of engineered GABA-releasing cells suppress tremor in an animal model of Parkinsonism. Neuroscience 2003 0.79
66 Complete amino acid sequence of the major early embryonic beta-like globin in chickens. J Biol Chem 1981 0.79
67 Reduced inhibitory capacity in prefrontal cortex of schizophrenics. Arch Gen Psychiatry 1995 0.78
68 Isolation of pharmacologically distinct GABA-benzodiazepine receptors by protein chemistry and molecular cloning. Adv Biochem Psychopharmacol 1990 0.77
69 Minor early embryonic chick hemoglobin M. Amino acid sequences of the epsilon and alpha D chains. J Biol Chem 1982 0.77
70 Sequence and regional distribution of the mRNA encoding the alpha 2 polypeptide of rat gamma-aminobutyric acidA receptors. J Neurochem 1991 0.77
71 RNA synthesis in avian erythroid cells. Dev Biol 1978 0.77
72 A transcriptional regulatory element of the gene encoding the 67,000-M(r) form of human glutamate decarboxylase is similar to a Drosophila regulatory element. J Neurochem 1992 0.77
73 Distribution of glutamic acid decarboxylase (Mr 67,000) in the basal ganglia of the rat: an immunohistochemical study with a selective cDNA-generated polyclonal antibody. J Neurocytol 1991 0.77
74 A rat brain cDNA encodes enzymatically active GABA transaminase and provides a molecular probe for GABA-catabolizing cells. J Neurochem 1994 0.77
75 Rat-1 fibroblasts engineered with GAD65 and GAD67 cDNAs in retroviral vectors produce and release GABA. J Neurochem 1993 0.76
76 Transcriptional regulation in avian erythroid cells. Biochemistry 1979 0.76
77 GABAA-benzodiazepine receptors: demonstration of pharmacological subtypes in the brain. Adv Exp Med Biol 1991 0.76
78 Pentobarbital decreases the gamma-aminobutyric acidA receptor subunit gamma-2 long/short mRNA ratio by a mechanism distinct from receptor occupation. J Pharmacol Exp Ther 1997 0.76
79 Recombinant adeno-associated virus (AAV) drives constitutive production of glutamate decarboxylase in neural cell lines. J Neurosci Res 1999 0.76
80 Identification of a familial mutation associated with GABA-transaminase deficiency disease. Neurobiol Dis 1998 0.76
81 Absence seizures decrease steroid modulation of t-[35S]butylbicyclophosphorothionate binding in thalamic relay nuclei. J Pharmacol Exp Ther 1998 0.75
82 Developmental regulation of globin and nonglobin messenger RNAs in avian erythroid cells. Dev Biol 1984 0.75
83 Comparison of the reproductive ecology of two sympatric blacktip sharks (Carcharhinus limbatus and Carcharhinus tilstoni) off north-eastern Australia with species identification inferred from vertebral counts. J Fish Biol 2012 0.75
84 Age and growth parameters of shark-like batoids. J Fish Biol 2014 0.75
85 Expression of mRNAs that encode D2 dopamine receptor subtypes: Anatomical, developmental, and pharmacological studies. Mol Cell Neurosci 1990 0.75
86 Alzheimer disease: enter molecular biology. Alzheimer Dis Assoc Disord 1987 0.75
87 Regional distribution of messenger RNAs in postmortem human brain. J Neurosci Res 1986 0.75
88 Lurcher Purkinje cells express glutamic acid decarboxylase and calbindin mRNAs. J Neurosci Res 1990 0.75
89 The abnormal cerebellar organization of Weaver and reeler mice does not affect the cellular distribution of three neuronal mRNAs. Neuron 1988 0.75
90 In situ hybridization of GAD mRNA in monkey and human brain: quantification at both regional and cellular levels. Neurosci Lett 1993 0.75
91 Expression of GABAA receptor polypeptides in clonal rat cell lines. Brain Res 1992 0.75
92 Spatial variation in the effects of size and age on reproductive dynamics of common coral trout Plectropomus leopardus. J Fish Biol 2014 0.75
93 The GABA receptor-chloride ion channel protein complex. Adv Exp Med Biol 1988 0.75
94 Presence of calbindin D28K and GAD67 mRNAs in both orthotopic and ectopic Purkinje cells of staggerer mice suggests that staggerer acts after the onset of cytodifferentiation. J Neurosci Res 1996 0.75
95 Amino acid sequences of the epsilon and alpha E globins of HbE, a minor early embryonic hemoglobin of the chicken. J Biol Chem 1982 0.75
96 Glutamic acid decarboxylase mRNA in rat brain: regional distribution and effects of intrastriatal kainic acid. Brain Res 1987 0.75
97 The heterogeneous nuclear RNA of chicken erythroblasts. Biochim Biophys Acta 1977 0.75