Prevalence of Alzheimer's disease and vascular dementia: association with education. The Rotterdam study.

PubWeight™: 3.42‹?› | Rank: Top 1%

🔗 View Article (PMC 2549358)

Published in BMJ on April 15, 1995

Authors

A Ott1, M M Breteler, F van Harskamp, J J Claus, T J van der Cammen, D E Grobbee, A Hofman

Author Affiliations

1: Erasmus University Medical School, Rotterdam, Netherlands.

Articles citing this

Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the american heart association/american stroke association. Stroke (2011) 10.11

The Rotterdam Study: objectives and design update. Eur J Epidemiol (2007) 5.78

The Rotterdam Study: 2010 objectives and design update. Eur J Epidemiol (2009) 3.44

The Rotterdam Study: 2012 objectives and design update. Eur J Epidemiol (2011) 3.26

The Rotterdam Study: 2014 objectives and design update. Eur J Epidemiol (2013) 2.56

Are sex and educational level independent predictors of dementia and Alzheimer's disease? Incidence data from the PAQUID project. J Neurol Neurosurg Psychiatry (1999) 2.33

Polypharmacy and falls in the middle age and elderly population. Br J Clin Pharmacol (2006) 2.02

Education and dementia. BMJ (1995) 1.90

A critique of the drug discovery and phase 3 clinical programs targeting the amyloid hypothesis for Alzheimer disease. Ann Neurol (2014) 1.83

The Rotterdam Study: 2016 objectives and design update. Eur J Epidemiol (2015) 1.61

A genomewide screen for late-onset Alzheimer disease in a genetically isolated Dutch population. Am J Hum Genet (2007) 1.55

Quantitative MRI findings and cognitive impairment among community dwelling elderly subjects. J Neurol Neurosurg Psychiatry (2002) 1.52

Very early detection of Alzheimer neuropathology and the role of brain reserve in modifying its clinical expression. J Geriatr Psychiatry Neurol (2005) 1.48

Relationship between education and dementia: an updated systematic review. Alzheimer Dis Assoc Disord (2011) 1.42

APOE epsilon 4 lowers age at onset and is a high risk factor for Alzheimer's disease; a case control study from central Norway. BMC Neurol (2008) 1.41

Rate of early onset Alzheimer's disease: a systematic review and meta-analysis. Ann Transl Med (2015) 1.41

Epidemiologic studies of modifiable factors associated with cognition and dementia: systematic review and meta-analysis. BMC Public Health (2014) 1.38

Measuring cognitive reserve based on the decomposition of episodic memory variance. Brain (2010) 1.35

beta-Amyloid degradation and Alzheimer's disease. J Biomed Biotechnol (2006) 1.35

A life course model of cognitive activities, socioeconomic status, education, reading ability, and cognition. J Am Geriatr Soc (2011) 1.27

Prevalence of the major mental disorders among the Korean elderly. J Korean Med Sci (2010) 1.15

Animal models in the drug discovery pipeline for Alzheimer's disease. Br J Pharmacol (2011) 1.13

Educating the brain to avoid dementia: can mental exercise prevent Alzheimer disease? PLoS Med (2005) 1.07

Mouse models to study the effect of cardiovascular risk factors on brain structure and cognition. J Cereb Blood Flow Metab (2013) 1.06

Prevalence of dementia in an elderly rural population: effects of age, sex, and education. J Neurol Neurosurg Psychiatry (1996) 1.06

Prevalence and pattern of cognitive impairment in rural and urban populations from Northern Portugal. BMC Neurol (2010) 1.05

Cognitive function in the Caerphilly study: associations with age social class, education and mood. Eur J Epidemiol (1999) 1.05

Association of lifetime intellectual enrichment with cognitive decline in the older population. JAMA Neurol (2014) 1.04

Are cognitively impaired individuals adequately represented in community surveys? Recruitment challenges and strategies to facilitate participation in community surveys of older adults. A review. Eur J Epidemiol (2000) 1.03

Traditional chinese medicine for senile dementia. Evid Based Complement Alternat Med (2011) 1.02

Development of screening guidelines and clinical criteria for predementia Alzheimer's disease. The DESCRIPA Study. Neuroepidemiology (2008) 1.00

Linkage and association studies identify a novel locus for Alzheimer disease at 7q36 in a Dutch population-based sample. Am J Hum Genet (2005) 1.00

Understanding dementia prevalence among centenarians. J Gerontol A Biol Sci Med Sci (2012) 0.99

Global epidemiology of dementia: Alzheimer's and vascular types. Biomed Res Int (2014) 0.99

Somatic mosaicism in the human genome. Genes (Basel) (2014) 0.99

A presenilin-1 truncating mutation is present in two cases with autopsy-confirmed early-onset Alzheimer disease. Am J Hum Genet (1998) 0.98

Frequency of subclinical heart disease in elderly persons with dementia. Am J Geriatr Cardiol (2007) 0.95

Vascular dementia. BMJ (1996) 0.95

Air pollution, oxidative stress, and Alzheimer's disease. J Environ Public Health (2012) 0.95

'Non-neuronopathic' Gaucher disease reconsidered. Prevalence of neurological manifestations in a Dutch cohort of type I Gaucher disease patients and a systematic review of the literature. J Inherit Metab Dis (2008) 0.95

Accounting for the relationship between low education and dementia: a twin study. Physiol Behav (2007) 0.94

A longitudinal study of risk factors for community-based home help services in Alzheimer's disease: the influence of cholinesterase inhibitor therapy. Clin Interv Aging (2013) 0.94

Factors affecting the age of onset and rate of progression of Alzheimer's disease. J Neurol Neurosurg Psychiatry (1998) 0.93

Caregiver- and patient-directed interventions for dementia: an evidence-based analysis. Ont Health Technol Assess Ser (2008) 0.90

Biomarkers in dementia: clinical utility and new directions. J Neurol Neurosurg Psychiatry (2014) 0.89

Clinicopathological outcomes of prospectively followed normal elderly brain bank volunteers. J Neuropathol Exp Neurol (2014) 0.89

Pathophysiology of vascular dementia. Immun Ageing (2009) 0.88

Comparison of brief cognitive tests and CSF biomarkers in predicting Alzheimer's disease in mild cognitive impairment: six-year follow-up study. PLoS One (2012) 0.88

Burden of disease due to dementia in the elderly population of Korea: present and future. BMC Public Health (2013) 0.87

Risk factors for dementia in the epidemiological study of Munguialde County (Basque Country-Spain). BMC Neurol (2008) 0.86

Dementia in the oldest old. Nat Rev Neurol (2013) 0.86

Clinical review: The thyroid in mind: cognitive function and low thyrotropin in older people. J Clin Endocrinol Metab (2012) 0.85

Potential cost-effectiveness of a family-based program in mild Alzheimer's disease patients. Eur J Health Econ (2004) 0.85

Prevalence of cognitive impairment in individuals aged over 65 in an urban area: DERIVA study. BMC Neurol (2011) 0.85

The gene encoding nicastrin, a major gamma-secretase component, modifies risk for familial early-onset Alzheimer disease in a Dutch population-based sample. Am J Hum Genet (2002) 0.85

Prevalence of dementia and main subtypes in rural northern China. Dement Geriatr Cogn Disord (2015) 0.85

Cognitive test performance predicts change in functional status at the population level: the MYHAT Project. J Int Neuropsychol Soc (2010) 0.84

Cerebral arachidonate cascade in dementia: Alzheimer's disease and vascular dementia. Curr Neuropharmacol (2006) 0.83

Can infections cause Alzheimer's disease? Epidemiol Rev (2013) 0.83

The Takeda three colors combination test: a screening test for detection of very mild Alzheimer's disease. ScientificWorldJournal (2014) 0.81

Plasma 24S-hydroxycholesterol levels in elderly subjects with late onset Alzheimer's disease or vascular dementia: a case-control study. BMC Neurol (2011) 0.81

A Population-based study of dementia in the oldest old: the Monzino 80-plus study. BMC Neurol (2011) 0.81

Characterizing Alzheimer's disease severity via resting-awake EEG amplitude modulation analysis. PLoS One (2013) 0.80

Neuropsychological indicators of preclinical Alzheimer's disease among depressed older adults. Neuropsychol Dev Cogn B Aging Neuropsychol Cogn (2013) 0.80

The Epidemiological Scale of Alzheimer's Disease. J Clin Med Res (2015) 0.80

From benefit to damage. Glutamate and advanced glycation end products in Alzheimer brain. J Neural Transm (Vienna) (2006) 0.80

BDNF variants, premorbid educational attainment, and disease characteristics in Alzheimer's disease: an exploratory study. J Alzheimers Dis (2009) 0.80

Heat-induced immunoreactivity of tau protein in neocortical neurons of fire fatalities. Int J Legal Med (2003) 0.79

Alois Alzheimer revisited: differences in origin of the disease carrying his name. J Neural Transm (Vienna) (2006) 0.79

Female CREBalphadelta- deficient mice show earlier age-related cognitive deficits than males. Neuroscience (2007) 0.78

Alzheimer Disease and Its Growing Epidemic: Risk Factors, Biomarkers, and the Urgent Need for Therapeutics. Neurol Clin (2016) 0.78

Predictors of the progression of dementia severity in brazilian patients with Alzheimer's disease and vascular dementia. Int J Alzheimers Dis (2010) 0.78

Free Recall Episodic Memory Performance Predicts Dementia Ten Years prior to Clinical Diagnosis: Findings from the Betula Longitudinal Study. Dement Geriatr Cogn Dis Extra (2015) 0.78

Gene-environment interaction between lead and Apolipoprotein E4 causes cognitive behavior deficits in mice. Mol Neurodegener (2017) 0.78

Population Normative Data for the CERAD Word List and Victoria Stroop Test in Younger- and Middle-Aged Adults: Cross-Sectional Analyses from the Framingham Heart Study. Exp Aging Res (2016) 0.77

Pro: Can neuropathology really confirm the exact diagnosis? Alzheimers Res Ther (2010) 0.77

Consistency of epidemiologic estimates. Eur J Epidemiol (2005) 0.77

Is the distinction between Alzheimer's disease and vascular dementia possible and relevant? Dialogues Clin Neurosci (2003) 0.76

Playing a Musical Instrument as a Protective Factor against Dementia and Cognitive Impairment: A Population-Based Twin Study. Int J Alzheimers Dis (2014) 0.76

Correlates of cognitive impairment in older Vietnamese. Aging Ment Health (2013) 0.76

Drug-induced cerebral glucose metabolism resembling Alzheimer's Disease: a case study. BMC Psychiatry (2015) 0.75

Education and prevalence of Alzheimer's disease and vascular dementia. A study of patients living in institutes may bias the findings. BMJ (1995) 0.75

Cost-effectiveness analysis of memantine for moderate-to-severe Alzheimer's disease in the Netherlands. Neuropsychiatr Dis Treat (2011) 0.75

Education and prevalence of Alzheimer's disease and vascular dementia. Premorbid ability influences measures used to identify dementia. BMJ (1995) 0.75

Cholinesterase inhibitors do not alter the length of stay in nursing homes among patients with Alzheimer's disease: a prospective, observational study of factors affecting survival time from admission to death. BMC Neurol (2016) 0.75

A T1 and DTI fused 3D corpus callosum analysis in MCI subjects with high and low cardiovascular risk profile. Neuroimage Clin (2016) 0.75

Biochemical aspects of dementias. Dialogues Clin Neurosci (2003) 0.75

Near-infrared spectroscopy (NIRS) and vagus somatosensory evoked potentials (VSEP) in the early diagnosis of Alzheimer's disease: rationale, design, methods, and first baseline data of the Vogel study. J Neural Transm (Vienna) (2017) 0.75

Profile of atypical-antipsychotics use in patients affected by dementia in the University Hospital of Ferrara. Eur J Clin Pharmacol (2010) 0.75

Perioperative management of delirium and dementia in the geriatric surgical patient. Langenbecks Arch Surg (2013) 0.75

MLC601 in vascular dementia: an efficacy and safety pilot study. Neuropsychiatr Dis Treat (2017) 0.75

Articles cited by this

"Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res (1975) 301.74

Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology (1984) 119.59

A new clinical scale for the staging of dementia. Br J Psychiatry (1982) 21.77

Vascular dementia: diagnostic criteria for research studies. Report of the NINDS-AIREN International Workshop. Neurology (1993) 16.92

Socioeconomic status and health: how education, income, and occupation contribute to risk factors for cardiovascular disease. Am J Public Health (1992) 15.38

Determinants of disease and disability in the elderly: the Rotterdam Elderly Study. Eur J Epidemiol (1991) 7.67

National trends in educational differentials in mortality. Am J Epidemiol (1989) 6.57

A semi-structured clinical interview for the assessment of diagnosis and mental state in the elderly: the Geriatric Mental State Schedule. I. Development and reliability. Psychol Med (1976) 5.86

Education and the prevalence of dementia and Alzheimer's disease. Neurology (1993) 4.68

Apolipoprotein E polymorphism and Alzheimer's disease. Lancet (1993) 4.47

The aging of America. Impact on health care costs. JAMA (1990) 4.10

The prevalence of dementia and Alzheimer's disease in Shanghai, China: impact of age, gender, and education. Ann Neurol (1990) 3.57

Cardiovascular disease and distribution of cognitive function in elderly people: the Rotterdam Study. BMJ (1994) 2.60

Frequency and distribution of Alzheimer's disease in Europe: a collaborative study of 1980-1990 prevalence findings. The EURODEM-Prevalence Research Group. Ann Neurol (1991) 1.89

Epidemiology, education, and the ecology of Alzheimer's disease. Neurology (1993) 1.73

Prevalence of clinically diagnosed Alzheimer's disease and other dementing disorders: a door-to-door survey in Appignano, Macerata Province, Italy. Neurology (1990) 1.68

[The Paquid research program on the epidemiology of dementia. Methods and initial results]. Rev Neurol (Paris) (1991) 1.43

A community-based study of dementia: the Rotterdam Elderly Study. Neuroepidemiology (1992) 1.33

Multi-infarct dementia. Neurol Clin (1983) 0.95

Articles by these authors

A new variant of Creutzfeldt-Jakob disease in the UK. Lancet (1996) 20.15

Vascular dementia: diagnostic criteria for research studies. Report of the NINDS-AIREN International Workshop. Neurology (1993) 16.92

Effects of a fixed combination of perindopril and indapamide on macrovascular and microvascular outcomes in patients with type 2 diabetes mellitus (the ADVANCE trial): a randomised controlled trial. Lancet (2007) 14.96

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. Nat Genet (2013) 9.46

Nonsteroidal antiinflammatory drugs and the risk of Alzheimer's disease. N Engl J Med (2001) 7.85

Ankle brachial index combined with Framingham Risk Score to predict cardiovascular events and mortality: a meta-analysis. JAMA (2008) 7.84

Determinants of disease and disability in the elderly: the Rotterdam Elderly Study. Eur J Epidemiol (1991) 7.67

Diabetes mellitus and the risk of dementia: The Rotterdam Study. Neurology (1999) 7.55

Bone mineral density, osteoporosis, and osteoporotic fractures: a genome-wide association study. Lancet (2008) 7.05

Common carotid intima-media thickness and risk of stroke and myocardial infarction: the Rotterdam Study. Circulation (1997) 7.03

Cerebral white matter lesions and cognitive function: the Rotterdam Scan Study. Ann Neurol (2000) 5.34

Fracture incidence and association with bone mineral density in elderly men and women: the Rotterdam Study. Bone (2004) 5.27

Diuretics, beta-blockers, and the risk for sudden cardiac death in hypertensive patients. Ann Intern Med (1995) 5.12

The prevalence of age-related maculopathy in the Rotterdam Study. Ophthalmology (1995) 5.08

Risk factors for age-related macular degeneration: Pooled findings from three continents. Ophthalmology (2001) 5.06

Atherosclerosis, apolipoprotein E, and prevalence of dementia and Alzheimer's disease in the Rotterdam Study. Lancet (1997) 5.04

Subclinical hypothyroidism is an independent risk factor for atherosclerosis and myocardial infarction in elderly women: the Rotterdam Study. Ann Intern Med (2000) 5.02

Age-specific prevalence and causes of blindness and visual impairment in an older population: the Rotterdam Study. Arch Ophthalmol (1998) 4.91

Cardiovascular mortality in Dutch men during 1996 European football championship: longitudinal population study. BMJ (2001) 4.87

Prevalence of cerebral white matter lesions in elderly people: a population based magnetic resonance imaging study. The Rotterdam Scan Study. J Neurol Neurosurg Psychiatry (2001) 4.51

The epidemiology of heart failure. Eur Heart J (1997) 4.31

Association between arterial stiffness and atherosclerosis: the Rotterdam Study. Stroke (2001) 3.99

Early outcome after off-pump versus on-pump coronary bypass surgery: results from a randomized study. Circulation (2001) 3.96

J-shaped relation between change in diastolic blood pressure and progression of aortic atherosclerosis. Lancet (1994) 3.95

Rates and risk factors for dementia and Alzheimer's disease: results from EURODEM pooled analyses. EURODEM Incidence Research Group and Work Groups. European Studies of Dementia. Neurology (1999) 3.95

The Emerging Risk Factors Collaboration: analysis of individual data on lipid, inflammatory and other markers in over 1.1 million participants in 104 prospective studies of cardiovascular diseases. Eur J Epidemiol (2007) 3.81

Prevalence and risk factors of cerebral microbleeds: the Rotterdam Scan Study. Neurology (2008) 3.76

Cerebral white matter lesions, vascular risk factors, and cognitive function in a population-based study: the Rotterdam Study. Neurology (1994) 3.75

The prevalence of dementia in Europe: a collaborative study of 1980-1990 findings. Eurodem Prevalence Research Group. Int J Epidemiol (1991) 3.70

J-shaped relation between blood pressure and stroke in treated hypertensives. Hypertension (1999) 3.51

External validation is necessary in prediction research: a clinical example. J Clin Epidemiol (2003) 3.49

Is dementia incidence declining?: Trends in dementia incidence since 1990 in the Rotterdam Study. Neurology (2012) 3.47

Confounding by indication: an example of variation in the use of epidemiologic terminology. Am J Epidemiol (1999) 3.44

Prevalence of dementia and major subtypes in Europe: A collaborative study of population-based cohorts. Neurologic Diseases in the Elderly Research Group. Neurology (2000) 3.39

Peripheral arterial disease in the elderly: The Rotterdam Study. Arterioscler Thromb Vasc Biol (1998) 3.37

The prevalence of primary open-angle glaucoma in a population-based study in The Netherlands. The Rotterdam Study. Ophthalmology (1994) 3.30

Smoking and risk of dementia and Alzheimer's disease in a population-based cohort study: the Rotterdam Study. Lancet (1998) 3.26

Changing views on open-angle glaucoma: definitions and prevalences--The Rotterdam Study. Invest Ophthalmol Vis Sci (2000) 3.19

Prevalence of heart failure and left ventricular dysfunction in the general population; The Rotterdam Study. Eur Heart J (1999) 3.18

Prevalence of parkinsonism and Parkinson's disease in Europe: the EUROPARKINSON Collaborative Study. European Community Concerted Action on the Epidemiology of Parkinson's disease. J Neurol Neurosurg Psychiatry (1997) 3.14

The prognosis of heart failure in the general population: The Rotterdam Study. Eur Heart J (2001) 3.07

Effect size estimates of lifestyle and dietary changes on all-cause mortality in coronary artery disease patients: a systematic review. Circulation (2005) 2.99

Maternal use of antiepileptic drugs and the risk of major congenital malformations: a joint European prospective study of human teratogenesis associated with maternal epilepsy. Epilepsia (1997) 2.82

Genetic association of apolipoprotein E with age-related macular degeneration. Am J Hum Genet (1998) 2.82

Age-related macular degeneration and smoking. The Rotterdam Study. Arch Ophthalmol (1996) 2.80

Cerebral white matter lesions and subjective cognitive dysfunction: the Rotterdam Scan Study. Neurology (2001) 2.80

Atrial fibrillation and dementia in a population-based study. The Rotterdam Study. Stroke (1997) 2.79

Creutzfeldt-Jakob disease and bovine spongiform encephalopathy: any connection? BMJ (1995) 2.74

Statins are associated with a reduced risk of Alzheimer disease regardless of lipophilicity. The Rotterdam Study. J Neurol Neurosurg Psychiatry (2008) 2.72

Bone density in non-insulin-dependent diabetes mellitus. The Rotterdam Study. Ann Intern Med (1995) 2.70

Dietary fat intake and the risk of incident dementia in the Rotterdam Study. Ann Neurol (1997) 2.67

Type 2 diabetes and atrophy of medial temporal lobe structures on brain MRI. Diabetologia (2003) 2.66

Apolipoprotein E4 allele in a population-based study of early-onset Alzheimer's disease. Nat Genet (1994) 2.65

Relation of alleles of the collagen type Ialpha1 gene to bone density and the risk of osteoporotic fractures in postmenopausal women. N Engl J Med (1998) 2.64

Statin use is associated with reduced incidence and progression of knee osteoarthritis in the Rotterdam study. Ann Rheum Dis (2011) 2.61

Cardiovascular disease and distribution of cognitive function in elderly people: the Rotterdam Study. BMJ (1994) 2.60

C-reactive protein and cerebral small-vessel disease: the Rotterdam Scan Study. Circulation (2005) 2.59

A comparison of body mass index, waist-hip ratio and waist circumference as predictors of all-cause mortality among the elderly: the Rotterdam study. Int J Obes Relat Metab Disord (2001) 2.55

Risk estimates of dementia by apolipoprotein E genotypes from a population-based incidence study: the Rotterdam Study. Arch Neurol (1998) 2.53

Trends in the prevalence of hypertension, antihypertensive therapy, and left ventricular hypertrophy from 1950 to 1989. N Engl J Med (1999) 2.53

Is carotid intima-media thickness useful in cardiovascular disease risk assessment? The Rotterdam Study. Stroke (2001) 2.49

Dietary antioxidants and cognitive function in a population-based sample of older persons. The Rotterdam Study. Am J Epidemiol (1996) 2.45