Cerebral white matter lesions, vascular risk factors, and cognitive function in a population-based study: the Rotterdam Study.

PubWeight™: 3.75‹?› | Rank: Top 1%

🔗 View Article (PMID 8035924)

Published in Neurology on July 01, 1994

Authors

M M Breteler1, J C van Swieten, M L Bots, D E Grobbee, J J Claus, J H van den Hout, F van Harskamp, H L Tanghe, P T de Jong, J van Gijn

Author Affiliations

1: Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands.

Articles citing this

(truncated to the top 100)

Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the american heart association/american stroke association. Stroke (2011) 10.11

The Rotterdam Study: objectives and design update. Eur J Epidemiol (2007) 5.78

Prevalence of cerebral white matter lesions in elderly people: a population based magnetic resonance imaging study. The Rotterdam Scan Study. J Neurol Neurosurg Psychiatry (2001) 4.51

The Rotterdam Study: 2010 objectives and design update. Eur J Epidemiol (2009) 3.44

The Rotterdam Study: 2012 objectives and design update. Eur J Epidemiol (2011) 3.26

Extent and distribution of white matter hyperintensities in normal aging, MCI, and AD. Neurology (2006) 3.22

Brain structure and obesity. Hum Brain Mapp (2010) 3.04

Neuropathological basis of magnetic resonance images in aging and dementia. Ann Neurol (2008) 2.71

The Rotterdam Study: 2014 objectives and design update. Eur J Epidemiol (2013) 2.56

Changes in white matter as determinant of global functional decline in older independent outpatients: three year follow-up of LADIS (leukoaraiosis and disability) study cohort. BMJ (2009) 2.51

The Secondary Prevention of Small Subcortical Strokes (SPS3) study. Int J Stroke (2011) 2.35

FLAIR histogram segmentation for measurement of leukoaraiosis volume. J Magn Reson Imaging (2001) 2.24

Spatial distribution of white-matter hyperintensities in Alzheimer disease, cerebral amyloid angiopathy, and healthy aging. Stroke (2008) 2.12

White matter changes compromise prefrontal cortex function in healthy elderly individuals. J Cogn Neurosci (2006) 2.06

The association between brain volumes, delirium duration, and cognitive outcomes in intensive care unit survivors: the VISIONS cohort magnetic resonance imaging study*. Crit Care Med (2012) 1.96

Total homocysteine is associated with white matter hyperintensity volume: the Northern Manhattan Study. Stroke (2005) 1.91

Cerebral white matter: neuroanatomy, clinical neurology, and neurobehavioral correlates. Ann N Y Acad Sci (2008) 1.85

Long-term blood pressure fluctuation and cerebrovascular disease in an elderly cohort. Arch Neurol (2010) 1.80

Brain white matter lesions detected by magnetic resonance [correction of resosnance] imaging are associated with balance and gait speed. J Neurol Neurosurg Psychiatry (2003) 1.77

Determinants of vascular dementia in the Cardiovascular Health Cognition Study. Neurology (2005) 1.70

Pattern of normal age-related regional differences in white matter microstructure is modified by vascular risk. Brain Res (2009) 1.63

Impact of metabolic syndrome on cognition and brain: a selected review of the literature. Arterioscler Thromb Vasc Biol (2012) 1.63

The Rotterdam Study: 2016 objectives and design update. Eur J Epidemiol (2015) 1.61

Metabolic and vascular determinants of impaired cognitive performance and abnormalities on brain magnetic resonance imaging in patients with type 2 diabetes. Diabetologia (2007) 1.59

Vulnerable neural systems and the borderland of brain aging and neurodegeneration. Neuron (2013) 1.54

Prenatal undernutrition and cognitive function in late adulthood. Proc Natl Acad Sci U S A (2010) 1.53

Quantitative MRI findings and cognitive impairment among community dwelling elderly subjects. J Neurol Neurosurg Psychiatry (2002) 1.52

Classification of white matter lesions on magnetic resonance imaging in elderly persons. Biol Psychiatry (2008) 1.45

Do brain image databanks support understanding of normal ageing brain structure? A systematic review. Eur Radiol (2012) 1.44

Exploring the effects of coexisting amyloid in subcortical vascular cognitive impairment. BMC Neurol (2015) 1.38

Different mechanisms of episodic memory failure in mild cognitive impairment. Neuropsychologia (2005) 1.37

Cardiovascular disease and cognitive function in maintenance hemodialysis patients. Am J Kidney Dis (2011) 1.35

Vascular and cognitive functions associated with cardiovascular disease in the elderly. J Clin Exp Neuropsychol (2008) 1.33

Brain regional lesion burden and impaired mobility in the elderly. Neurobiol Aging (2009) 1.31

Associations between Alzheimer disease biomarkers, neurodegeneration, and cognition in cognitively normal older people. JAMA Neurol (2013) 1.29

White matter hyperintensities as a predictor of neuropsychological deficits post-stroke. J Neurol Neurosurg Psychiatry (2005) 1.24

Exercise and cognition in older adults: is there a role for resistance training programmes? Br J Sports Med (2008) 1.24

Depression and cognitive function in maintenance hemodialysis patients. Am J Kidney Dis (2010) 1.24

Inter-individual variation in blood pressure is associated with regional white matter integrity in generally healthy older adults. Neuroimage (2011) 1.22

Effect of central nervous system medication use on decline in cognition in community-dwelling older adults: findings from the Health, Aging And Body Composition Study. J Am Geriatr Soc (2009) 1.22

Vascular disease and dementias: paradigm shifts to drive research in new directions. Alzheimers Dement (2012) 1.21

Differential impact of cerebral white matter changes, diabetes, hypertension and stroke on cognitive performance among non-disabled elderly. The LADIS study. J Neurol Neurosurg Psychiatry (2007) 1.17

History of coronary heart disease and cognitive performance in midlife: the Whitehall II study. Eur Heart J (2008) 1.17

Clinical differences among mild cognitive impairment subtypes in Parkinson's disease. Mov Disord (2012) 1.15

Ischemic stroke in the elderly: an overview of evidence. Nat Rev Neurol (2010) 1.15

Genetic variants of the NOTCH3 gene in the elderly and magnetic resonance imaging correlates of age-related cerebral small vessel disease. Brain (2011) 1.13

Presence of a central vein within white matter lesions on susceptibility weighted imaging: a specific finding for multiple sclerosis? Neuroradiology (2010) 1.09

White matter lesions defined by diffusion tensor imaging in older adults. Ann Neurol (2011) 1.09

Review article: implications of vascular aging. Anesth Analg (2011) 1.09

Cerebral perfusion is associated with white matter hyperintensities in older adults with heart failure. Congest Heart Fail (2013) 1.07

Neuroanatomical localisation and clinical correlates of white matter lesions in the elderly. J Neurol Neurosurg Psychiatry (2004) 1.06

Brain atrophy associations with white matter lesions in the ageing brain: the Lothian Birth Cohort 1936. Eur Radiol (2012) 1.05

Research advances in geriatric depression. World Psychiatry (2009) 1.03

Associations between white matter hyperintensities and β amyloid on integrity of projection, association, and limbic fiber tracts measured with diffusion tensor MRI. PLoS One (2013) 1.03

Thrombogenic microvesicles and white matter hyperintensities in postmenopausal women. Neurology (2013) 1.01

Age- and sex-specific rates of leukoaraiosis in TIA and stroke patients: population-based study. Neurology (2012) 1.00

Clinical, imaging, and pathological heterogeneity of the Alzheimer's disease syndrome. Alzheimers Res Ther (2013) 0.99

The association between cognitive function and white matter lesion location in older adults: a systematic review. BMC Neurol (2012) 0.96

Executive function mediates effects of white matter hyperintensities on episodic memory. Neuropsychologia (2011) 0.95

Vascular dementia. BMJ (1996) 0.95

Vitamin D and subclinical cerebrovascular disease: the Atherosclerosis Risk in Communities brain magnetic resonance imaging study. JAMA Neurol (2014) 0.94

The impact of vascular burden on late-life depression. Brain Res Rev (2009) 0.94

Pathways linking regional hyperintensities in the brain and slower gait. Neuroimage (2014) 0.94

Hyperintense MRI lesions in bipolar disorder: A meta-analysis and review. Int Rev Psychiatry (2009) 0.92

The "central vein sign": is there a place for susceptibility weighted imaging in possible multiple sclerosis? Eur Radiol (2013) 0.92

Is Alzheimer's disease a systemic disease? Biochim Biophys Acta (2014) 0.92

Interindividual variation in serum cholesterol is associated with regional white matter tissue integrity in older adults. Hum Brain Mapp (2012) 0.91

In vivo vascular hallmarks of diffuse leukoaraiosis. J Magn Reson Imaging (2010) 0.91

Treatment for cerebral small vessel disease: effect of relaxin on the function and structure of cerebral parenchymal arterioles during hypertension. FASEB J (2013) 0.91

Leukoaraiosis and collaterals in acute ischemic stroke. J Neuroimaging (2010) 0.89

Processing speed in normal aging: effects of white matter hyperintensities and hippocampal volume loss. Neuropsychol Dev Cogn B Aging Neuropsychol Cogn (2013) 0.88

Development and decline of memory functions in normal, pathological and healthy successful aging. Brain Topogr (2011) 0.88

Monounsaturated, trans, and saturated Fatty acids and cognitive decline in women. J Am Geriatr Soc (2011) 0.87

Vascular dementia: prevention and treatment. Clin Interv Aging (2006) 0.87

The renin-angiotensin-aldosterone system in cerebral small vessel disease. J Neurol (2008) 0.87

The case for an elderly targeted stroke management. Front Neurol (2011) 0.86

Reduced blood flow in normal white matter predicts development of leukoaraiosis. J Cereb Blood Flow Metab (2015) 0.85

Associations between Ambulatory Blood Pressure Parameters and Cerebral White Matter Lesions. Int J Hypertens (2011) 0.85

DTI parameters of axonal integrity and demyelination of the optic radiation correlate with glaucoma indices. Graefes Arch Clin Exp Ophthalmol (2012) 0.85

Loss of callosal fibre integrity in healthy elderly with age-related white matter changes. J Neurol (2011) 0.84

Automated detection of white matter signal abnormality using T2 relaxometry: application to brain segmentation on term MRI in very preterm infants. Neuroimage (2012) 0.84

White matter hyperintensities and the course of depressive symptoms in elderly people with mild dementia. Dement Geriatr Cogn Dis Extra (2012) 0.84

Clinical treatment reverses attentional deficits in congestive heart failure. BMC Geriatr (2001) 0.84

Leukoaraiosis is a chronic atherosclerotic disease. ScientificWorldJournal (2012) 0.84

The effects of white matter hyperintensities and amyloid deposition on Alzheimer dementia. Neuroimage Clin (2015) 0.84

Clinical symptoms and risk factors in cerebral microangiopathy patients. PLoS One (2013) 0.83

Neuroimaging of cerebrovascular disease in the aging brain. Aging Dis (2012) 0.83

Current status and future perspectives of magnetic resonance high-field imaging: a summary. Neuroimaging Clin N Am (2012) 0.83

Age-related signal intensity changes in the corpus callosum: assessment with three orthogonal FLAIR images. Eur Radiol (2005) 0.83

Neuropsychological profile in a large group of heart transplant candidates. PLoS One (2011) 0.83

Late-life depression with comorbid cognitive impairment and disability: nonpharmacological interventions. Clin Interv Aging (2010) 0.83

Association of white matter hyperintensities and gray matter volume with cognition in older individuals without cognitive impairment. Brain Struct Funct (2015) 0.83

Profiles by sex of brain MRI and cognitive function in the framingham offspring study. Alzheimer Dis Assoc Disord (2010) 0.82

Dementia and Alzheimer's disease: a new direction.The 2010 Jay L. Foster Memorial Lecture. Alzheimers Dement (2011) 0.82

Cognition and incident coronary heart disease in late midlife: The Whitehall II study. Intelligence (2009) 0.82

Age-dependent association between cigarette smoking on white matter hyperintensities. Neurol Sci (2011) 0.81

Hypertension, cognitive decline, and dementia: an epidemiological perspective. Dialogues Clin Neurosci (2007) 0.81

White Matter Lesions Are Not Related to β-Amyloid Deposition in an Autopsy-Based Study. Curr Gerontol Geriatr Res (2011) 0.81

Cerebral white matter hyperintensities in the prediction of cognitive decline and incident dementia. Int Rev Psychiatry (2013) 0.81

Magnetization transfer ratio of white matter hyperintensities in subcortical ischemic vascular dementia. AJNR Am J Neuroradiol (1999) 0.81

Articles by these authors

Interobserver agreement for the assessment of handicap in stroke patients. Stroke (1988) 20.14

Effects of a fixed combination of perindopril and indapamide on macrovascular and microvascular outcomes in patients with type 2 diabetes mellitus (the ADVANCE trial): a randomised controlled trial. Lancet (2007) 14.96

Aspirin plus dipyridamole versus aspirin alone after cerebral ischaemia of arterial origin (ESPRIT): randomised controlled trial. Lancet (2006) 10.72

An international classification and grading system for age-related maculopathy and age-related macular degeneration. The International ARM Epidemiological Study Group. Surv Ophthalmol (1995) 10.05

Determinants of disease and disability in the elderly: the Rotterdam Elderly Study. Eur J Epidemiol (1991) 7.67

Diabetes mellitus and the risk of dementia: The Rotterdam Study. Neurology (1999) 7.55

Common carotid intima-media thickness and risk of stroke and myocardial infarction: the Rotterdam Study. Circulation (1997) 7.03

Cerebral white matter lesions and cognitive function: the Rotterdam Scan Study. Ann Neurol (2000) 5.34

Diuretics, beta-blockers, and the risk for sudden cardiac death in hypertensive patients. Ann Intern Med (1995) 5.12

The prevalence of age-related maculopathy in the Rotterdam Study. Ophthalmology (1995) 5.08

Risk factors for age-related macular degeneration: Pooled findings from three continents. Ophthalmology (2001) 5.06

Atherosclerosis, apolipoprotein E, and prevalence of dementia and Alzheimer's disease in the Rotterdam Study. Lancet (1997) 5.04

Age-specific prevalence and causes of blindness and visual impairment in an older population: the Rotterdam Study. Arch Ophthalmol (1998) 4.91

Cardiovascular mortality in Dutch men during 1996 European football championship: longitudinal population study. BMJ (2001) 4.87

Prevalence of cerebral white matter lesions in elderly people: a population based magnetic resonance imaging study. The Rotterdam Scan Study. J Neurol Neurosurg Psychiatry (2001) 4.51

The epidemiology of heart failure. Eur Heart J (1997) 4.31

Case-fatality rates and functional outcome after subarachnoid hemorrhage: a systematic review. Stroke (1997) 4.13

Prevalence and risk of rupture of intracranial aneurysms: a systematic review. Stroke (1998) 4.12

Association between arterial stiffness and atherosclerosis: the Rotterdam Study. Stroke (2001) 3.99

Early outcome after off-pump versus on-pump coronary bypass surgery: results from a randomized study. Circulation (2001) 3.96

J-shaped relation between change in diastolic blood pressure and progression of aortic atherosclerosis. Lancet (1994) 3.95

Incidence of subarachnoid hemorrhage: role of region, year, and rate of computed tomography: a meta-analysis. Stroke (1996) 3.67

J-shaped relation between blood pressure and stroke in treated hypertensives. Hypertension (1999) 3.51

External validation is necessary in prediction research: a clinical example. J Clin Epidemiol (2003) 3.49

Long-term survival and vascular event risk after transient ischaemic attack or minor ischaemic stroke: a cohort study. Lancet (2005) 3.46

Prevalence of Alzheimer's disease and vascular dementia: association with education. The Rotterdam study. BMJ (1995) 3.42

Peripheral arterial disease in the elderly: The Rotterdam Study. Arterioscler Thromb Vasc Biol (1998) 3.37

Morphometric analysis of Bruch's membrane, the choriocapillaris, and the choroid in aging. Invest Ophthalmol Vis Sci (1994) 3.37

[Fever, large eyes and confusion; the anticholinergic syndrome]. Ned Tijdschr Geneeskd (2002) 3.30

The prevalence of primary open-angle glaucoma in a population-based study in The Netherlands. The Rotterdam Study. Ophthalmology (1994) 3.30

Smoking and risk of dementia and Alzheimer's disease in a population-based cohort study: the Rotterdam Study. Lancet (1998) 3.26

Changing views on open-angle glaucoma: definitions and prevalences--The Rotterdam Study. Invest Ophthalmol Vis Sci (2000) 3.19

Prevalence of heart failure and left ventricular dysfunction in the general population; The Rotterdam Study. Eur Heart J (1999) 3.18

The prognosis of heart failure in the general population: The Rotterdam Study. Eur Heart J (2001) 3.07

Effect size estimates of lifestyle and dietary changes on all-cause mortality in coronary artery disease patients: a systematic review. Circulation (2005) 2.99

[Those who cannot remember the past are condemned to repeat it]. Ned Tijdschr Geneeskd (2006) 2.98

Intracerebral hematomas during anticoagulant treatment. Stroke (1990) 2.97

Mutations in ABCC6 cause pseudoxanthoma elasticum. Nat Genet (2000) 2.89

Maternal use of antiepileptic drugs and the risk of major congenital malformations: a joint European prospective study of human teratogenesis associated with maternal epilepsy. Epilepsia (1997) 2.82

Genetic association of apolipoprotein E with age-related macular degeneration. Am J Hum Genet (1998) 2.82

Age-related macular degeneration and smoking. The Rotterdam Study. Arch Ophthalmol (1996) 2.80

Atrial fibrillation and dementia in a population-based study. The Rotterdam Study. Stroke (1997) 2.79

Bone density in non-insulin-dependent diabetes mellitus. The Rotterdam Study. Ann Intern Med (1995) 2.70

Magnesium sulfate in aneurysmal subarachnoid hemorrhage: a randomized controlled trial. Stroke (2005) 2.69

Cardiovascular disease and distribution of cognitive function in elderly people: the Rotterdam Study. BMJ (1994) 2.60

Trends in the prevalence of hypertension, antihypertensive therapy, and left ventricular hypertrophy from 1950 to 1989. N Engl J Med (1999) 2.53

Is carotid intima-media thickness useful in cardiovascular disease risk assessment? The Rotterdam Study. Stroke (2001) 2.49

Dietary antioxidants and cognitive function in a population-based sample of older persons. The Rotterdam Study. Am J Epidemiol (1996) 2.45

A polymorphism in the glucocorticoid receptor gene may be associated with and increased sensitivity to glucocorticoids in vivo. J Clin Endocrinol Metab (1998) 2.45

Third generation oral contraceptives and risk of venous thrombosis: meta-analysis. BMJ (2001) 2.43

Primary open-angle glaucoma, intraocular pressure, and systemic blood pressure in the general elderly population. The Rotterdam Study. Ophthalmology (1995) 2.43

Does drug treatment improve survival? Reconciling the trials in mild-to-moderate hypertension. J Hypertens (1995) 2.40

Presenile dementia and cerebral haemorrhage linked to a mutation at codon 692 of the beta-amyloid precursor protein gene. Nat Genet (1992) 2.40

Calcium antagonists in patients with aneurysmal subarachnoid hemorrhage: a systematic review. Neurology (1998) 2.39

Measures of bioavailable serum testosterone and estradiol and their relationships with muscle strength, bone density, and body composition in elderly men. J Clin Endocrinol Metab (2000) 2.36

Microalbuminuria is common, also in a nondiabetic, nonhypertensive population, and an independent indicator of cardiovascular risk factors and cardiovascular morbidity. J Intern Med (2001) 2.35

Spinal dural arteriovenous fistulas: a congestive myelopathy that initially mimics a peripheral nerve disorder. Brain (2006) 2.35

Hypertension and cerebral white matter lesions in a prospective cohort study. Brain (2002) 2.31

Comparison between measures of atherosclerosis and risk of stroke: the Rotterdam Study. Stroke (2003) 2.31

Genetic risk of age-related maculopathy. Population-based familial aggregation study. Arch Ophthalmol (1998) 2.31

Outcome in patients with subarachnoid haemorrhage and negative angiography according to pattern of haemorrhage on computed tomography. Lancet (1991) 2.30

Prevalence of Parkinson's disease in the elderly: the Rotterdam Study. Neurology (1995) 2.30

The diagnosis of subarachnoid haemorrhage. J Neurol Neurosurg Psychiatry (1990) 2.29

Increased expression of angiogenic growth factors in age-related maculopathy. Br J Ophthalmol (1997) 2.28

Limitations of sensitivity, specificity, likelihood ratio, and bayes' theorem in assessing diagnostic probabilities: a clinical example. Epidemiology (1997) 2.28

Carotid intima-media thickness at different sites: relation to incident myocardial infarction; The Rotterdam Study. Eur Heart J (2002) 2.22

Serologic and polymerase chain reaction analysis of intraocular fluids in the diagnosis of infectious uveitis. Am J Ophthalmol (1996) 2.20

Periventricular lesions in the white matter on magnetic resonance imaging in the elderly. A morphometric correlation with arteriolosclerosis and dilated perivascular spaces. Brain (1991) 2.18

Perimesencephalic hemorrhage: a nonaneurysmal and benign form of subarachnoid hemorrhage. Neurology (1985) 2.18

Incidence, risk, and case fatality of first ever stroke in the elderly population. The Rotterdam Study. J Neurol Neurosurg Psychiatry (2003) 2.18

QTc dispersion predicts cardiac mortality in the elderly: the Rotterdam Study. Circulation (1998) 2.15

Distinct genetic forms of frontotemporal dementia. Neurology (2008) 2.15

Grading white matter lesions on CT and MRI: a simple scale. J Neurol Neurosurg Psychiatry (1990) 2.15

Cognitive correlates of ventricular enlargement and cerebral white matter lesions on magnetic resonance imaging. The Rotterdam Study. Stroke (1994) 2.14