Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Amiloride-sensitive epithelial Na+ channel is made of three homologous subunits.
|
Nature
|
1994
|
9.76
|
2
|
CFTR as a cAMP-dependent regulator of sodium channels.
|
Science
|
1995
|
6.50
|
3
|
Epithelial sodium channel related to proteins involved in neurodegeneration.
|
Nature
|
1993
|
6.04
|
4
|
Early death due to defective neonatal lung liquid clearance in alpha-ENaC-deficient mice.
|
Nat Genet
|
1996
|
4.15
|
5
|
An epithelial serine protease activates the amiloride-sensitive sodium channel.
|
Nature
|
1997
|
3.87
|
6
|
Mutations in subunits of the epithelial sodium channel cause salt wasting with hyperkalaemic acidosis, pseudohypoaldosteronism type 1.
|
Nat Genet
|
1996
|
3.58
|
7
|
Cell surface expression of the epithelial Na channel and a mutant causing Liddle syndrome: a quantitative approach.
|
Proc Natl Acad Sci U S A
|
1996
|
3.37
|
8
|
Corticosteroid-dependent sodium transport in a novel immortalized mouse collecting duct principal cell line.
|
J Am Soc Nephrol
|
1999
|
2.88
|
9
|
A mutation in the epithelial sodium channel causing Liddle disease increases channel activity in the Xenopus laevis oocyte expression system.
|
Proc Natl Acad Sci U S A
|
1995
|
2.69
|
10
|
Membrane topology of the epithelial sodium channel in intact cells.
|
Am J Physiol
|
1994
|
2.69
|
11
|
Identification of a PY motif in the epithelial Na channel subunits as a target sequence for mutations causing channel activation found in Liddle syndrome.
|
EMBO J
|
1996
|
2.39
|
12
|
The heterotetrameric architecture of the epithelial sodium channel (ENaC).
|
EMBO J
|
1998
|
2.34
|
13
|
Distribution of transcellular calcium and sodium transport pathways along mouse distal nephron.
|
Am J Physiol Renal Physiol
|
2001
|
2.28
|
14
|
Cell-specific expression of epithelial sodium channel alpha, beta, and gamma subunits in aldosterone-responsive epithelia from the rat: localization by in situ hybridization and immunocytochemistry.
|
J Cell Biol
|
1994
|
2.18
|
15
|
Aldosterone induces rapid apical translocation of ENaC in early portion of renal collecting system: possible role of SGK.
|
Am J Physiol Renal Physiol
|
2001
|
2.13
|
16
|
A de novo missense mutation of the beta subunit of the epithelial sodium channel causes hypertension and Liddle syndrome, identifying a proline-rich segment critical for regulation of channel activity.
|
Proc Natl Acad Sci U S A
|
1995
|
2.10
|
17
|
An SH3 binding region in the epithelial Na+ channel (alpha rENaC) mediates its localization at the apical membrane.
|
EMBO J
|
1994
|
2.10
|
18
|
A role for the beta-subunit in the expression of functional Na+-K+-ATPase in Xenopus oocytes.
|
Am J Physiol
|
1989
|
1.92
|
19
|
The highly selective low-conductance epithelial Na channel of Xenopus laevis A6 kidney cells.
|
Am J Physiol
|
1995
|
1.65
|
20
|
Transcriptome of a mouse kidney cortical collecting duct cell line: effects of aldosterone and vasopressin.
|
Proc Natl Acad Sci U S A
|
2001
|
1.64
|
21
|
Cystic fibrosis transmembrane conductance regulator inverts protein kinase A-mediated regulation of epithelial sodium channel single channel kinetics.
|
J Biol Chem
|
1997
|
1.61
|
22
|
Aldosterone-induced increase in the abundance of Na+ channel subunits.
|
Am J Physiol
|
1996
|
1.59
|
23
|
Activation of the amiloride-sensitive epithelial sodium channel by the serine protease mCAP1 expressed in a mouse cortical collecting duct cell line.
|
J Am Soc Nephrol
|
2000
|
1.58
|
24
|
Differential subcellular localization of ENaC subunits in mouse kidney in response to high- and low-Na diets.
|
Am J Physiol Renal Physiol
|
2000
|
1.47
|
25
|
Mutational analysis of cysteine-rich domains of the epithelium sodium channel (ENaC). Identification of cysteines essential for channel expression at the cell surface.
|
J Biol Chem
|
1999
|
1.46
|
26
|
A mutation causing pseudohypoaldosteronism type 1 identifies a conserved glycine that is involved in the gating of the epithelial sodium channel.
|
EMBO J
|
1997
|
1.46
|
27
|
Mutations causing Liddle syndrome reduce sodium-dependent downregulation of the epithelial sodium channel in the Xenopus oocyte expression system.
|
J Clin Invest
|
1998
|
1.45
|
28
|
Early effect of aldosterone on the rate of synthesis of the epithelial sodium channel alpha subunit in A6 renal cells.
|
J Am Soc Nephrol
|
1997
|
1.39
|
29
|
Primary sequence and functional expression of a novel ouabain-resistant Na,K-ATPase. The beta subunit modulates potassium activation of the Na,K-pump.
|
J Biol Chem
|
1992
|
1.38
|
30
|
A mouse model for the renal salt-wasting syndrome pseudohypoaldosteronism.
|
Proc Natl Acad Sci U S A
|
1997
|
1.37
|
31
|
Epithelial Na+ channel subunits in rat taste cells: localization and regulation by aldosterone.
|
J Comp Neurol
|
1999
|
1.37
|
32
|
Salt restriction induces pseudohypoaldosteronism type 1 in mice expressing low levels of the beta-subunit of the amiloride-sensitive epithelial sodium channel.
|
Proc Natl Acad Sci U S A
|
1999
|
1.33
|
33
|
Liddle disease caused by a missense mutation of beta subunit of the epithelial sodium channel gene.
|
J Clin Invest
|
1996
|
1.30
|
34
|
A mouse model for Liddle's syndrome.
|
J Am Soc Nephrol
|
1999
|
1.30
|
35
|
Modulation of the Na,K-pump function by beta subunit isoforms.
|
J Gen Physiol
|
1994
|
1.28
|
36
|
Lung epithelial Na channel subunits are differentially regulated during development and by steroids.
|
Am J Physiol
|
1995
|
1.21
|
37
|
Relative expression of the human epithelial Na+ channel subunits in normal and cystic fibrosis airways.
|
Am J Physiol
|
1995
|
1.19
|
38
|
Phosphorylation of the Na,K-ATPase alpha-subunit by protein kinase A and C in vitro and in intact cells. Identification of a novel motif for PKC-mediated phosphorylation.
|
J Biol Chem
|
1994
|
1.19
|
39
|
Hormonal regulation of (Na+,K+)-ATPase biosynthesis in the toad bladder. Effect of aldosterone and 3,5,3'-triiodo-L-thyronine.
|
J Biol Chem
|
1982
|
1.18
|
40
|
Mutation of a cysteine in the first transmembrane segment of Na,K-ATPase alpha subunit confers ouabain resistance.
|
EMBO J
|
1992
|
1.17
|
41
|
Aldosterone regulation of gene transcription leading to control of ion transport.
|
Hypertension
|
1992
|
1.17
|
42
|
Processing, intracellular transport, and functional expression of endogenous and exogenous alpha-beta 3 Na,K-ATPase complexes in Xenopus oocytes.
|
J Biol Chem
|
1992
|
1.15
|
43
|
Primary sequence of Xenopus laevis Na+-K+-ATPase and its localization in A6 kidney cells.
|
Am J Physiol
|
1989
|
1.09
|
44
|
Membrane insertion of alpha- and beta-subunits of Na+,K+-ATPase.
|
J Biol Chem
|
1985
|
1.07
|
45
|
IGF-1 vs insulin: respective roles in modulating sodium transport via the PI-3 kinase/Sgk1 pathway in a cortical collecting duct cell line.
|
Kidney Int
|
2006
|
1.06
|
46
|
Regulation by aldosterone of Na+,K+-ATPase mRNAs, protein synthesis, and sodium transport in cultured kidney cells.
|
J Cell Biol
|
1987
|
1.06
|
47
|
Expression of the epithelial Na+ channel in the developing rat lung.
|
Am J Physiol
|
1993
|
1.06
|
48
|
Structure-function relationship of Na,K-ATPase.
|
Annu Rev Physiol
|
1991
|
1.04
|
49
|
Coexpression of alpha 1 with putative beta 3 subunits results in functional Na+/K+ pumps in Xenopus oocytes.
|
Proc Natl Acad Sci U S A
|
1991
|
1.04
|
50
|
Role of the transmembrane and extracytoplasmic domain of beta subunits in subunit assembly, intracellular transport, and functional expression of Na,K-pumps.
|
J Cell Biol
|
1993
|
1.03
|
51
|
Identification of a highly conserved sequence at the N-terminus of the epithelial Na+ channel alpha subunit involved in gating.
|
Pflugers Arch
|
1999
|
1.02
|
52
|
Epithelial sodium channel regulatory proteins identified by functional expression cloning.
|
Kidney Int Suppl
|
1998
|
1.00
|
53
|
Primary structure of an apical protein from Xenopus laevis that participates in amiloride-sensitive sodium channel activity.
|
J Cell Biol
|
1992
|
0.99
|
54
|
Immunochemical evidence for a transmembrane orientation of both the (Na+, K+)-ATPase subunits.
|
Biochemistry
|
1981
|
0.99
|
55
|
Functional expression of a pseudohypoaldosteronism type I mutated epithelial Na+ channel lacking the pore-forming region of its alpha subunit.
|
J Clin Invest
|
1999
|
0.99
|
56
|
Developmental expression of sodium entry pathways in rat nephron.
|
Am J Physiol
|
1999
|
0.98
|
57
|
Novel isoforms of the beta and gamma subunits of the Xenopus epithelial Na channel provide information about the amiloride binding site and extracellular sodium sensing.
|
Proc Natl Acad Sci U S A
|
1997
|
0.96
|
58
|
A putative H(+)-K(+)-ATPase is selectively expressed in surface epithelial cells of rat distal colon.
|
Am J Physiol
|
1993
|
0.96
|
59
|
The H,K-ATPase beta-subunit can act as a surrogate for the beta-subunit of Na,K-pumps.
|
J Biol Chem
|
1991
|
0.96
|
60
|
Receptor occupancy vs. induction of Na+-K+-ATPase and Na+ transport by aldosterone.
|
Am J Physiol
|
1985
|
0.95
|
61
|
Aldosterone induces a rapid increase in the rate of Na,K-ATPase gene transcription in cultured kidney cells.
|
Mol Endocrinol
|
1989
|
0.95
|
62
|
Amiloride-sensitive sodium channels in confluent M-1 mouse cortical collecting duct cells.
|
J Membr Biol
|
1995
|
0.95
|
63
|
Salt- and angiotensin II-dependent variations in amiloride-sensitive rectal potential difference in mice.
|
Clin Exp Pharmacol Physiol
|
2000
|
0.94
|
64
|
Mutation of a tyrosine in the H3-H4 ectodomain of Na,K-ATPase alpha subunit confers ouabain resistance.
|
J Biol Chem
|
1993
|
0.94
|
65
|
Role of the Na,K-ATPase beta-subunit in the cellular accumulation and maturation of the enzyme as assessed by glycosylation inhibitors.
|
J Membr Biol
|
1988
|
0.93
|
66
|
Cloning of a bovine renal epithelial Na+ channel subunit.
|
Am J Physiol
|
1995
|
0.91
|
67
|
Primary structure and functional expression of the mouse and frog alpha-subunit of the gastric H(+)-K(+)-ATPase.
|
Am J Physiol
|
1995
|
0.90
|
68
|
Effects of butyrate on histone deacetylation and aldosterone-dependent Na+ transport in the toad bladder.
|
J Biol Chem
|
1983
|
0.90
|
69
|
Maturation of the catalytic alpha-subunit of Na,K-ATPase during intracellular transport.
|
J Cell Biol
|
1987
|
0.88
|
70
|
Aldosterone regulation of Na+ transport and Na+-K+-ATPase in A6 cells: role of growth conditions.
|
Am J Physiol
|
1987
|
0.88
|
71
|
The rat distal colon P-ATPase alpha subunit encodes a ouabain-sensitive H+, K+-ATPase.
|
J Biol Chem
|
1996
|
0.88
|
72
|
Kinetics of RNA labeling in toad bladder epithelium: effects of aldosterone and related steroids.
|
Proc Natl Acad Sci U S A
|
1974
|
0.87
|
73
|
Localization of epithelial sodium channel and aquaporin-2 in rabbit kidney cortex.
|
Am J Physiol Renal Physiol
|
2000
|
0.87
|
74
|
Mechanisms of urinary K+ and H+ excretion: primary structure and functional expression of a novel H,K-ATPase.
|
J Cell Biol
|
1993
|
0.86
|
75
|
A reappraisal of aldosterone effects on the kidney: new insights provided by epithelial sodium channel cloning.
|
Curr Opin Nephrol Hypertens
|
1997
|
0.86
|
76
|
Inhibition of N-glycosylation affects transepithelial Na+ but not Na+-K+-ATPase transport.
|
Am J Physiol
|
1989
|
0.86
|
77
|
Functional expression of the amiloride-sensitive sodium channel in Xenopus oocytes.
|
Proc Natl Acad Sci U S A
|
1989
|
0.85
|
78
|
Binding and antimineralocorticoid activities of spirolactones in toad bladder.
|
Am J Physiol
|
1983
|
0.85
|
79
|
Localization of alpha-isoforms of Na(+)-K(+)-ATPase in rat kidney by in situ hybridization.
|
Am J Physiol
|
1991
|
0.85
|
80
|
Functional expression of N-terminal truncated alpha-subunits of Na,K-ATPase in Xenopus laevis oocytes.
|
FEBS Lett
|
1991
|
0.84
|
81
|
Thyroid hormone antagonizes an aldosterone-induced protein: a candidate mediator for the late mineralocorticoid response.
|
J Membr Biol
|
1986
|
0.84
|
82
|
Spironolactone antagonism of aldosterone action on Na+ transport and RNA metabolism in toad bladder epithelium.
|
J Membr Biol
|
1977
|
0.84
|
83
|
Ontogeny of alpha 1- and beta 1-isoforms of Na(+)-K(+)-ATPase in fetal distal rat lung epithelium.
|
Am J Physiol
|
1993
|
0.83
|
84
|
Differential regulation of Na-K-ATPase isoform gene expression by T3 during rat brain development.
|
Am J Physiol
|
1991
|
0.83
|
85
|
Expression cloning of the epithelial sodium channel.
|
Kidney Int
|
1995
|
0.83
|
86
|
Neonatal injection of native proton pump antigens induces autoimmune gastritis in mice.
|
Gastroenterology
|
1997
|
0.83
|
87
|
Functional analyses of a N-terminal splice variant of the alpha subunit of the epithelial sodium channel.
|
Cell Physiol Biochem
|
2001
|
0.83
|
88
|
Control of transepithelial Na+ transport and Na-K-ATPase by oxytocin and aldosterone.
|
Am J Physiol
|
1986
|
0.82
|
89
|
Role of RNA in the action of aldosterone on Na+ transport.
|
J Membr Biol
|
1978
|
0.82
|
90
|
Effects of thyromimetic drugs on aldosterone-dependent sodium transport in the toad bladder.
|
J Membr Biol
|
1984
|
0.81
|
91
|
Labeling of a cysteine in the cardiotonic glycoside binding site by the steroid derivative HDMA.
|
FEBS Lett
|
1995
|
0.81
|
92
|
Human ATP1AL1 gene encodes a ouabain-sensitive H-K-ATPase.
|
Am J Physiol
|
1995
|
0.81
|
93
|
Effects of 3'deoxyadenosine and actinomycin D on RNA synthesis in toad bladder: analysis of response to aldosterone.
|
J Membr Biol
|
1978
|
0.81
|
94
|
Sodium-independent effect of aldosterone on initial rate of ouabain binding in A6 cells.
|
Am J Physiol
|
1992
|
0.80
|
95
|
Steroid metabolism determines mineralocorticoid specificity in the toad bladder.
|
Am J Physiol
|
1989
|
0.80
|
96
|
Rat liver 11 beta-hydroxysteroid dehydrogenase complementary deoxyribonucleic acid encodes oxoreductase activity in a mineralocorticoid-responsive toad bladder cell line.
|
Endocrinology
|
1993
|
0.80
|
97
|
Compensatory up-regulation of angiotensin II subtype 1 receptors in alpha ENaC knockout heterozygous mice.
|
Kidney Int
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2001
|
0.79
|
98
|
Thyroid hormone-aldosterone interaction on Na+ transport in toad bladder.
|
Am J Physiol
|
1979
|
0.79
|
99
|
The beta subunit modulates potassium activation of the Na-K pump.
|
Ann N Y Acad Sci
|
1992
|
0.79
|
100
|
Physiological and pathophysiological role of the epithelial sodium channel in the control of blood pressure.
|
Kidney Blood Press Res
|
1996
|
0.79
|
101
|
Thyroid hormone-aldosterone antagonism on Na+ transport in toad bladder. Evidence for a triiodothyronine nuclear receptor.
|
J Biol Chem
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1981
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0.79
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102
|
Unusual degradation of alpha-beta complexes in Xenopus oocytes by beta-subunits of Xenopus gastric H-K-ATPase.
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Am J Physiol
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1998
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0.78
|
103
|
Effects of thyroid hormones and aldosterone on mineralocorticoid binding sites in the toad bladder.
|
J Membr Biol
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1984
|
0.78
|
104
|
Polymorphisms in the carboxy-terminus of the epithelial sodium channel in rat models for hypertension.
|
J Hypertens
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1997
|
0.78
|
105
|
Purification and characterization of (Na+ + K+)-ATPase from toad kidney.
|
Biochim Biophys Acta
|
1979
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0.78
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106
|
Sodium channels in membrane vesicles from cultured toad bladder cells.
|
Am J Physiol
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1988
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0.77
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107
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Structural organization of alpha-subunit from purified and microsomal toad kidney (Na+ + K+)-ATPase as assessed by controlled trypsinolysis.
|
Biochim Biophys Acta
|
1987
|
0.77
|
108
|
Hydrophobic labeling of (Na+,K+)-ATPase: further evidence that the beta subunit is embedded in the membrane bilayer.
|
Biochemistry
|
1983
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0.77
|
109
|
Actions of aldosterone on polyadenylated ribonucleic acid and Na+ transport in the toad bladder.
|
Biochemistry
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1976
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0.77
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110
|
Microfilament-rich cells in the toad bladder epithelium.
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J Membr Biol
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1979
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0.77
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111
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Cytoplasmic and nuclear uptake of aldosterone in toad bladder: a mathematical modeling approach.
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Am J Physiol
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1985
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0.77
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112
|
SCNN1, an epithelial cell sodium channel gene in the conserved linkage group on mouse chromosome 6 and human chromosome 12.
|
Genomics
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1994
|
0.77
|
113
|
Role of the epithelial sodium channel in lung liquid clearance.
|
Chest
|
1997
|
0.76
|
114
|
Mutation of a conserved proline residue in the beta-subunit ectodomain prevents Na(+)-K(+)-ATPase oligomerization.
|
Am J Physiol
|
1993
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0.76
|
115
|
Na(+)-K(+)-ATPase gene expression during in vitro development of rat fetal forebrain.
|
Am J Physiol
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1990
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0.76
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116
|
Three ATPase activities have an abnormal developmental time course in trembler sciatic nerves.
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Dev Neurosci
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1987
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0.76
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117
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Primary sequence and functional expression of a novel beta subunit of the P-ATPase gene family.
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Pflugers Arch
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1993
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0.76
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118
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Effects of aldosterone on Na,K-ATPase transcription, mRNAs, and protein synthesis, and on transepithelial Na+ transport in A6 cells.
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Prog Clin Biol Res
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119
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Corticosterone induces 11 beta-HSD and mineralocorticoid specificity in an amphibian urinary bladder cell line.
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120
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The amiloride receptor.
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Clin Investig
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Isolation and separation of toad bladder epithelial cells.
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J Membr Biol
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122
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Aldosterone-induced glycoproteins: electrophysiological-biochemical correlation.
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Biochim Biophys Acta
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123
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Inhibition of the anti-natriuretic action of aldosterone by thyroid hormone in the rat.
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Rev Med Suisse Romande
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126
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Purification of PRL receptors from toad kidney: comparisons with rabbit mammary PRL receptors.
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Am J Physiol
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1988
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0.75
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127
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Polyadenylation of Na(+)-K(+)-ATPase beta 1-subunit during early development of Xenopus laevis.
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Am J Physiol
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1994
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0.75
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128
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Effects of tunicamycin on the cellular expression and structural arrangement of Na K-ATPase.
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Prog Clin Biol Res
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129
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[Mechanism of action of aldosterone on the toad bladder: correlation between biological response and occupation of the receptor sites].
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Distinct epitopes on amiloride.
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Am J Physiol
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132
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Thyroxine and Na+ transport in toad: role in transition from poikilo- to homeothermy.
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Am J Physiol
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1979
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0.75
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133
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Actions of aldosterone on rRNA and Na+ transport in the toad bladder.
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Biochemistry
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1976
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0.75
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134
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Effects of 3'-deoxycytidine on rRNA synthesis in toad bladder: analysis of response to aldosterone.
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Am J Physiol
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1977
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0.75
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135
|
Testosterone: a specific competitive antagonist of aldosterone in the toad bladder.
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Am J Physiol
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1980
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0.75
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136
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Biosynthesis of the catalytic subunit of (Na+, K+)-ATPase in toad kidney and toad bladder epithelial cells.
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Prog Clin Biol Res
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1982
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0.75
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137
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Inactivation of sodium-transporting proteins in the kidney.
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Pflugers Arch
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2002
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0.75
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138
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Poles apart. A Forefront Symposium on the Organization of Membrane Polarity in Epithelial Cells sponsored by the International Society of Nephrology, the Swiss National Science Fund, and the 450th Anniversary Fund of the University of Lausanne, Arolla, Switzerland, July 2-6, 1989.
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New Biol
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1989
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0.75
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139
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Specific binding sites for ovine prolactin in three amphibian cell lines.
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Am J Physiol
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1985
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0.75
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