Published in J Cell Biol on June 01, 1995
LDL receptor-related protein 1: unique tissue-specific functions revealed by selective gene knockout studies. Physiol Rev (2008) 3.46
The gamma/sigma1 and alpha/sigma2 hemicomplexes of clathrin adaptors AP-1 and AP-2 harbor the dileucine recognition site. Mol Biol Cell (2007) 1.83
The cytoplasmic domain of the LDL receptor-related protein regulates multiple steps in APP processing. EMBO J (2002) 1.79
Transmembrane and cytoplasmic domains of syndecan mediate a multi-step endocytic pathway involving detergent-insoluble membrane rafts. Biochem J (2000) 1.59
Nuclear targeting by the growth factor midkine. Mol Cell Biol (2002) 1.44
Proprotein convertase subtilisin/kexin type 9 (PCSK9) can mediate degradation of the low density lipoprotein receptor-related protein 1 (LRP-1). PLoS One (2013) 1.18
Trypanosoma cruzi utilizes the host low density lipoprotein receptor in invasion. PLoS Negl Trop Dis (2011) 1.17
Inflammatory mediators promote production of shed LRP1/CD91, which regulates cell signaling and cytokine expression by macrophages. J Leukoc Biol (2010) 1.05
Identification of acidic dileucine signals in LRP9 that interact with both GGAs and AP-1/AP-2. Traffic (2008) 1.05
Cationic sites on granzyme B contribute to cytotoxicity by promoting its uptake into target cells. Mol Cell Biol (2005) 1.04
LDL receptor-related protein-1 is a sialic-acid-independent receptor for myelin-associated glycoprotein that functions in neurite outgrowth inhibition by MAG and CNS myelin. J Cell Sci (2012) 1.02
Furin regulates both the activation of Pseudomonas exotoxin A and the Quantity of the toxin receptor expressed on target cells. Infect Immun (1996) 1.02
Identification of a major cyclic AMP-dependent protein kinase A phosphorylation site within the cytoplasmic tail of the low-density lipoprotein receptor-related protein: implication for receptor-mediated endocytosis. Mol Cell Biol (2001) 1.02
Targeting surface nucleolin with multivalent HB-19 and related Nucant pseudopeptides results in distinct inhibitory mechanisms depending on the malignant tumor cell type. BMC Cancer (2011) 0.98
Proteasome regulates the delivery of LDL receptor-related protein into the degradation pathway. Mol Biol Cell (2002) 0.98
The diphthamide modification on elongation factor-2 renders mammalian cells resistant to ricin. Cell Microbiol (2008) 0.93
Effect of human acetylcholinesterase subunit assembly on its circulatory residence. Biochem J (2001) 0.90
N-methyl-D-aspartate receptor inhibition by an apolipoprotein E-derived peptide relies on low-density lipoprotein receptor-associated protein. Neuropharmacology (2008) 0.86
LDL receptor-related protein 1 regulates the abundance of diverse cell-signaling proteins in the plasma membrane proteome. J Proteome Res (2010) 0.84
LRAD3, a novel low-density lipoprotein receptor family member that modulates amyloid precursor protein trafficking. J Neurosci (2011) 0.82
Characterization of a Chinese hamster ovary cell mutant having a mutation in elongation factor-2. PLoS One (2010) 0.80
Slow endocytosis of the LDL receptor-related protein 1B: implications for a novel cytoplasmic tail conformation. Exp Cell Res (2007) 0.80
Coagulation factor IX mediates serotype-specific binding of species A adenoviruses to host cells. J Virol (2011) 0.77
Enhanced macrophage resistance to Pseudomonas exotoxin A is correlated with decreased expression of the low-density lipoprotein receptor-related protein. Infect Immun (1999) 0.77
Engulfment protein GULP is regulator of transforming growth factor-β response in ovarian cells. J Biol Chem (2012) 0.76
Serpin-Enzyme Receptors LDL Receptor-Related Protein 1. Methods Enzymol (2011) 0.75
LRP1 Modulates APP Intraneuronal Transport and Processing in Its Monomeric and Dimeric State. Front Mol Neurosci (2017) 0.75
Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes. J Mol Biol (1986) 55.34
Surface location and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor. EMBO J (1988) 4.54
Low density lipoprotein receptor-related protein mediates uptake of cholesteryl esters derived from apoprotein E-enriched lipoproteins. Proc Natl Acad Sci U S A (1989) 3.26
Sequence identity between the alpha 2-macroglobulin receptor and low density lipoprotein receptor-related protein suggests that this molecule is a multifunctional receptor. J Biol Chem (1990) 3.25
LDL receptor-related protein internalizes and degrades uPA-PAI-1 complexes and is essential for embryo implantation. Cell (1992) 3.12
ADP-ribosylation of elongation factor 2 by diphtheria toxin. NMR spectra and proposed structures of ribosyl-diphthamide and its hydrolysis products. J Biol Chem (1980) 2.41
The alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein binds and internalizes Pseudomonas exotoxin A. J Biol Chem (1992) 2.40
In vitro inhibition of diphtheria toxin action by ammonium salts and amines. J Bacteriol (1965) 2.38
Low density lipoprotein receptor-related protein and gp330 bind similar ligands, including plasminogen activator-inhibitor complexes and lactoferrin, an inhibitor of chylomicron remnant clearance. J Biol Chem (1992) 2.27
Receptor-mediated internalization of Pseudomonas toxin by mouse fibroblasts. Cell (1980) 2.17
Pseudomonas exotoxin contains a specific sequence at the carboxyl terminus that is required for cytotoxicity. Proc Natl Acad Sci U S A (1990) 2.12
Processing of Pseudomonas exotoxin by a cellular protease results in the generation of a 37,000-Da toxin fragment that is translocated to the cytosol. J Biol Chem (1990) 2.04
Expression of mouse furin in a Chinese hamster cell resistant to Pseudomonas exotoxin A and viruses complements the genetic lesion. J Biol Chem (1993) 1.94
A novel mechanism for controlling the activity of alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein. Multiple regulatory sites for 39-kDa receptor-associated protein. J Biol Chem (1992) 1.89
Low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor is an hepatic receptor for tissue-type plasminogen activator. Proc Natl Acad Sci U S A (1992) 1.88
Proteolytic processing of the 600 kd low density lipoprotein receptor-related protein (LRP) occurs in a trans-Golgi compartment. EMBO J (1990) 1.82
Fusions of anthrax toxin lethal factor to the ADP-ribosylation domain of Pseudomonas exotoxin A are potent cytotoxins which are translocated to the cytosol of mammalian cells. J Biol Chem (1992) 1.71
Evidence that the newly cloned low-density-lipoprotein receptor related protein (LRP) is the alpha 2-macroglobulin receptor. FEBS Lett (1990) 1.65
Increased cytotoxic activity of Pseudomonas exotoxin and two chimeric toxins ending in KDEL. J Biol Chem (1991) 1.61
Cleavage of pseudomonas exotoxin and diphtheria toxin by a furin-like enzyme prepared from beef liver. J Biol Chem (1994) 1.43
The mannose 6-phosphate receptor of Chinese Hamster ovary cells. Isolation of mutants with altered receptors. J Biol Chem (1981) 1.42
The human alpha 2-macroglobulin receptor: identification of a 420-kD cell surface glycoprotein specific for the activated conformation of alpha 2-macroglobulin. J Cell Biol (1990) 1.40
In vitro biosynthesis of diphthamide, studied with mutant Chinese hamster ovary cells resistant to diphtheria toxin. Mol Cell Biol (1984) 1.40
Cell-mediated cleavage of Pseudomonas exotoxin between Arg279 and Gly280 generates the enzymatically active fragment which translocates to the cytosol. J Biol Chem (1992) 1.38
Mutational analysis of domain I of Pseudomonas exotoxin. Mutations in domain I of Pseudomonas exotoxin which reduce cell binding and animal toxicity. J Biol Chem (1988) 1.35
A delayed-early gene activated by fibroblast growth factor-1 encodes a protein related to aldose reductase. J Biol Chem (1994) 1.32
The 39-kDa receptor-associated protein regulates ligand binding by the very low density lipoprotein receptor. J Biol Chem (1994) 1.30
Pseudomonas exotoxin: chimeric toxins. J Biol Chem (1989) 1.23
Structure, function, and regulation of Pseudomonas aeruginosa exotoxin A. Annu Rev Microbiol (1990) 1.18
Three new complementation groups of temperature-sensitive Chinese hamster ovary cell mutants defective in the endocytic pathway. Somat Cell Mol Genet (1988) 1.12
The low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor binds and mediates catabolism of bovine milk lipoprotein lipase. J Biol Chem (1992) 1.06
Low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor mediates cellular uptake of pro-urokinase. J Biol Chem (1993) 1.05
Characterization of diphtheria-toxin-resistant mutants lacking receptor function or containing nonribosylatable elongation factor 2. Somat Cell Mol Genet (1985) 0.97
Isolation and characterization of Pseudomonas aeruginosa exotoxin A binding glycoprotein from mouse LM cells. J Biol Chem (1991) 0.96
Purification of the human placental alpha 2-macroglobulin receptor. FEBS Lett (1989) 0.93
Regulation of endocytic processes by pH. Trends Pharmacol Sci (1988) 0.90
Use of anti-idiotypic antibodies to establish that monoclonal antibody 7H11D6 binds to the alpha 2-macroglobulin receptor recognition site. J Biol Chem (1988) 0.81
Trafficking of Pseudomonas exotoxin A in mammalian cells. Eur J Clin Microbiol (1985) 0.80
Human pregnancy zone protein and alpha 2-macroglobulin. High-affinity binding of complexes to the same receptor on fibroblasts and characterization by monoclonal antibodies. J Biol Chem (1986) 0.79
Endocytosis and lysosomal delivery of tissue plasminogen activator-inhibitor 1 complexes in Hep G2 cells. Blood (1992) 0.77
Role of exotoxin and protease as possible virulence factors in experimental infections with Pseudomonas aeruginosa. Infect Immun (1978) 3.15
Effects of anthrax toxin components on human neutrophils. Infect Immun (1985) 2.51
The alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein binds and internalizes Pseudomonas exotoxin A. J Biol Chem (1992) 2.40
Possible association of a reduction in cardiovascular events with blood donation. Heart (1997) 2.39
Malignant melanoma: social status and outdoor work. Br J Cancer (1980) 2.18
Receptor-mediated internalization of Pseudomonas toxin by mouse fibroblasts. Cell (1980) 2.17
A novel TNF receptor family member binds TWEAK and is implicated in angiogenesis. Immunity (2001) 2.16
Inhibition of diphtheria toxin degradation and cytotoxic action by chloroquine. J Biol Chem (1980) 2.06
Experimental studies on the pathogenesis of infections due to Pseudomonas aeruginosa: direct evidence for toxin production during Pseudomonas infection of burned skin tissues. J Infect Dis (1977) 1.84
Identification by targeted differential display of an immediate early gene encoding a putative serine/threonine kinase. J Biol Chem (1995) 1.80
The Fn14 immediate-early response gene is induced during liver regeneration and highly expressed in both human and murine hepatocellular carcinomas. Am J Pathol (2000) 1.73
The accuracy of portable cholesterol analyzers in public screening programs. JAMA (1990) 1.65
Accumulation and decay of DG42 gene products follow a gradient pattern during Xenopus embryogenesis. Dev Biol (1988) 1.53
The mitogen-inducible Fn14 gene encodes a type I transmembrane protein that modulates fibroblast adhesion and migration. J Biol Chem (1999) 1.53
Stage-specific keratins in Xenopus laevis embryos and tadpoles: the XK81 gene family. J Cell Biol (1986) 1.47
The effect of cuff size on blood pressure measurement in adults. Epidemiology (1991) 1.43
Cleavage of pseudomonas exotoxin and diphtheria toxin by a furin-like enzyme prepared from beef liver. J Biol Chem (1994) 1.43
Cell-mediated cleavage of Pseudomonas exotoxin between Arg279 and Gly280 generates the enzymatically active fragment which translocates to the cytosol. J Biol Chem (1992) 1.38
Chemical modulation of diphtheria toxin action on cultured mammalian cells. Infect Immun (1975) 1.37
Receptor-mediated entry of diphtheria toxin into monkey kidney (Vero) cells: electron microscopic evaluation. Infect Immun (1985) 1.36
Cytokine cooperation in renal tubular cell injury: the role of TWEAK. Kidney Int (2006) 1.34
Interaction of cultured mammalian cells with [125I] diphtheria toxin. Infect Immun (1975) 1.34
Proteases from human immunodeficiency virus and avian myeloblastosis virus show distinct specificities in hydrolysis of multidomain protein substrates. J Virol (1990) 1.33
A delayed-early gene activated by fibroblast growth factor-1 encodes a protein related to aldose reductase. J Biol Chem (1994) 1.32
Developmentally regulated cytokeratin gene in Xenopus laevis. Mol Cell Biol (1985) 1.29
A randomized trial of dexamethasone and acetazolamide for acute mountain sickness prophylaxis. Am J Med (1987) 1.28
Furin-mediated cleavage of Pseudomonas exotoxin-derived chimeric toxins. J Biol Chem (1997) 1.21
Isolation of tumor cell growth-inhibiting factors from a human rhabdomyosarcoma cell line. Cancer Res (1985) 1.20
Distinct patterns of expression of fibroblast growth factors and their receptors in human atheroma and nonatherosclerotic arteries. Association of acidic FGF with plaque microvessels and macrophages. J Clin Invest (1993) 1.20
Melanomas of eye: stability of rates. Am J Epidemiol (1981) 1.17
Receptor-mediated entry of Pseudomonas toxin: methylamine blocks clustering step. Infect Immun (1983) 1.15
Age-specific reference ranges for serum prostate-specific antigen. Urology (1995) 1.12
Constitutive endothelin-1 overexpression promotes smooth muscle cell proliferation via an external autocrine loop. J Biol Chem (1994) 1.08
Femtosecond laser pulse shaping by use of microsecond radio-frequency pulses. Opt Lett (1994) 1.07
Urinary mutagens in municipal sewage workers and water treatment workers. Am J Epidemiol (1986) 1.06
Two distinct tumor cell growth-inhibiting factors from a human rhabdomyosarcoma cell line. Cancer Res (1985) 1.05
Inhibition of protein synthesis after intravenous or intramuscular challenge with diphtheria toxin. Infect Immun (1972) 1.05
Expression and phosphorylation of fibroblast-growth-factor-inducible kinase (Fnk) during cell-cycle progression. Biochem J (1998) 1.01
Role of the low-density lipoprotein receptor-related protein in beta-amyloid metabolism and Alzheimer disease. Arch Neurol (2000) 1.00
Measurement of spinal mobility. Ann Rheum Dis (1974) 1.00
Reduced temperature alters Pseudomonas exotoxin A entry into the mouse LM cell. Infect Immun (1986) 1.00
Fibroblast growth factor-1 induces phosphofructokinase, fatty acid synthase and Ca(2+)-ATPase mRNA expression in NIH 3T3 cells. Biochem Biophys Res Commun (1993) 0.97
Evidence for pseudomonas exotoxin A receptors on plasma membrane of toxin-sensitive lm fibroblasts. Infect Immun (1984) 0.97
Isolation and characterization of Pseudomonas aeruginosa exotoxin A binding glycoprotein from mouse LM cells. J Biol Chem (1991) 0.96
Human coagulation factor FVIIa (recombinant) in the management of limb-threatening bleeds unresponsive to alternative therapies: results from the NovoSeven emergency-use programme in patients with severe haemophilia or with acquired inhibitors. Blood Coagul Fibrinolysis (2000) 0.96
Expression of the very low-density lipoprotein receptor (VLDL-r), an apolipoprotein-E receptor, in the central nervous system and in Alzheimer's disease. J Neuropathol Exp Neurol (1996) 0.95
Interleukin 1 regulates heparin-binding growth factor 2 gene expression in vascular smooth muscle cells. Proc Natl Acad Sci U S A (1991) 0.94
PIG3V, an immortalized human vitiligo melanocyte cell line, expresses dilated endoplasmic reticulum. In Vitro Cell Dev Biol Anim (2000) 0.93
Interaction of pseudomonas exoproducts with phagocytic cells. Can J Microbiol (1982) 0.93
Visualization of intracellular trafficking: use of biotinylated ligands in conjunction with avidin-gold colloids. J Histochem Cytochem (1984) 0.92
Selective attrition of non-recirculating T cells during normal passage through the lung vascular bed. Immunology (1990) 0.92
Drosophila ribosomal RNA stability increases during slow growth conditions. J Biol Chem (1985) 0.91
Essential role of calcium in cellular internalization of Pseudomonas toxin. Infect Immun (1982) 0.91
Diphtheria toxin does not enter resistant cells by receptor-mediated endocytosis. Infect Immun (1983) 0.90
Oxidized LDL mediates the release of fibroblast growth factor-1. Arterioscler Thromb Vasc Biol (1997) 0.90
Placental chorioangioma: prenatal diagnosis and clinical significance. Am J Perinatol (1993) 0.89
Studies on the effect of diphtheria toxin on protein synthesis in mice. J Med Microbiol (1973) 0.89
Identification of a murine TEF-1-related gene expressed after mitogenic stimulation of quiescent fibroblasts and during myogenic differentiation. J Biol Chem (1996) 0.89
Differential stability of Drosophila embryonic mRNAs during subsequent larval development. J Cell Biol (1985) 0.89
Angiotensin II and endothelin-1 increase fibroblast growth factor-2 mRNA expression in vascular smooth muscle cells. Biochem Biophys Res Commun (1998) 0.88
Polypeptide growth factors and phorbol ester induce progressive ankylosis (ank) gene expression in murine and human fibroblasts. J Cell Biochem (2001) 0.88
Health among municipal sewage and water treatment workers. Toxicol Ind Health (1987) 0.88
FGF-1 affixation stimulates ePTFE endothelialization without intimal hyperplasia. J Surg Res (1994) 0.87
Endocytosis of urokinase-plasminogen activator inhibitor type 1 complexes bound to a chimeric transmembrane urokinase receptor. J Biol Chem (1994) 0.86
Heparin-binding growth factor-1 stimulation of human endothelial cells induces platelet-derived growth factor A-chain gene expression. J Biol Chem (1990) 0.86
Prevalence of upper extremity neuropathy in a clinical dentist population. J Am Dent Assoc (1993) 0.86
Mucosal administration of a chimera composed of Pseudomonas exotoxin and the gp120 V3 loop sequence of HIV-1 induces both salivary and serum antibody responses. Vaccine (1999) 0.85
Characterization of V3 loop-Pseudomonas exotoxin chimeras. Candidate vaccines for human immunodeficiency virus-1. J Biol Chem (1998) 0.85
Uptake of diphtheria toxin and its fragment A moiety by mammalian cells in culture. Infect Immun (1976) 0.85
Comparisons of genomic structures and chromosomal locations of the mouse aldose reductase and aldose reductase-like genes. Eur J Biochem (1999) 0.85
Human fibroblast growth factor 1 gene expression in vascular smooth muscle cells is modulated via an alternate promoter in response to serum and phorbol ester. Nucleic Acids Res (1995) 0.84
Gene expression in Xenopus embryogenesis. J Embryol Exp Morphol (1985) 0.84
Hypersensitivity responses to bee venom and the mellitin. Int Arch Allergy Appl Immunol (1974) 0.84
Problems in the production and use of 5 nm avidin-gold colloids. J Microsc (1986) 0.84
Dietary-induced atherosclerotic lesions have increased levels of acidic FGF mRNA and altered cytoskeletal and extracellular matrix mRNA expression. J Vasc Res (1994) 0.84
Hypertension Prevention Trial (HPT): food pattern changes resulting from intervention on sodium, potassium, and energy intake. Hypertension Prevention Trial Research Group. J Am Diet Assoc (1990) 0.84
Level of receptor-associated protein moderates cellular susceptibility to pseudomonas exotoxin A. Infect Immun (1995) 0.83
Status of infants at birth and risk for adverse neonatal events and long-term sequelae: a study in low birth weight infants. Am J Obstet Gynecol (1987) 0.83
Polymerization of tubulin in apoptotic cells is not cell cycle dependent. Exp Cell Res (1994) 0.83
Differential display using random hexamer-primed cDNA, motif primers, and agarose gel electrophoresis. Methods Mol Biol (1997) 0.82
Selection of Pseudomonas exotoxin-resistant cells with altered expression of alpha 2MR/LRP. Ann N Y Acad Sci (1994) 0.82
Differential regulation of acidic and basic fibroblast growth factor gene expression in fibroblast growth factor-treated rat aortic smooth muscle cells. Circ Res (1994) 0.82
Fibroblast growth factor-1-inducible gene FR-17 encodes a nonmuscle alpha-actinin isoform. J Cell Physiol (1996) 0.82
Heparin-binding epidermal growth factor-like growth factor regulates fibroblast growth factor-2 expression in aortic smooth muscle cells. Circ Res (1996) 0.81
Resistance of exotoxin A to purified Pseudomonas proteolytic enzymes. Infect Immun (1980) 0.80
Differential control of murine aldose reductase and fibroblast growth factor (FGF)-regulated-1 gene expression in NIH 3T3 cells by FGF-1 treatment and hyperosmotic stress. Biochem J (1997) 0.80
Immunoregulation of asthma: control of T-lymphocyte activation in the respiratory tract. Eur Respir J Suppl (1991) 0.80
A simple reliable method for producing electron dense markers of uniform size for use in immunoelectron microscopy. J Immunol Methods (1982) 0.80
The half-lives of platelet-derived growth factor A- and B-chain mRNAs are similar in endothelial cells and unaffected by heparin-binding growth factor-1 or cycloheximide. J Cell Physiol (1991) 0.80
Studies on the mode of action of diphtheria toxin. VI. Inhibition of protein synthesis induced by local infection with toxingenic Corynebacterium diphtheriae. Proc Soc Exp Biol Med (1973) 0.80
Trafficking of Pseudomonas exotoxin A in mammalian cells. Eur J Clin Microbiol (1985) 0.80
Musculoskeletal pain among general dentists. Gen Dent (1988) 0.80
Fibroblast growth factor-1 stimulation of quiescent NIH 3T3 cells increases G/T mismatch-binding protein expression. Biochem J (1996) 0.79