Cell-mediated cleavage of Pseudomonas exotoxin between Arg279 and Gly280 generates the enzymatically active fragment which translocates to the cytosol.

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Published in J Biol Chem on December 15, 1992

Authors

M Ogata1, C M Fryling, I Pastan, D J FitzGerald

Author Affiliations

1: Laboratory of Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892.

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