Published in Kidney Int on September 27, 2006
The TWEAK-Fn14 cytokine-receptor axis: discovery, biology and therapeutic targeting. Nat Rev Drug Discov (2008) 3.25
Soluble TWEAK and PTX3 in nondialysis CKD patients: impact on endothelial dysfunction and cardiovascular outcomes. Clin J Am Soc Nephrol (2011) 1.77
Inhibition of the TWEAK/Fn14 pathway attenuates renal disease in nephrotoxic serum nephritis. Clin Immunol (2012) 1.74
The inflammatory cytokines TWEAK and TNFα reduce renal klotho expression through NFκB. J Am Soc Nephrol (2011) 1.45
The cytokine TWEAK modulates renal tubulointerstitial inflammation. J Am Soc Nephrol (2008) 1.43
Additive effects of soluble TWEAK and inflammation on mortality in hemodialysis patients. Clin J Am Soc Nephrol (2008) 1.22
TNF superfamily: a growing saga of kidney injury modulators. Mediators Inflamm (2010) 1.20
Etiopathology of chronic tubular, glomerular and renovascular nephropathies: clinical implications. J Transl Med (2011) 1.18
Role of TWEAK in lupus nephritis: a bench-to-bedside review. J Autoimmun (2012) 1.15
Combined therapy with renin-angiotensin system and calcium channel blockers in type 2 diabetic hypertensive patients with proteinuria: effects on soluble TWEAK, PTX3, and flow-mediated dilation. Clin J Am Soc Nephrol (2010) 1.07
TWEAK activates the non-canonical NFkappaB pathway in murine renal tubular cells: modulation of CCL21. PLoS One (2010) 1.07
Tweak induces proliferation in renal tubular epithelium: a role in uninephrectomy induced renal hyperplasia. J Cell Mol Med (2009) 1.07
The TWEAK-Fn14 system as a potential drug target. Br J Pharmacol (2013) 0.96
Urinary TWEAK level as a marker of lupus nephritis activity in 46 cases. J Biomed Biotechnol (2012) 0.95
Deficiency of fibroblast growth factor-inducible 14 (Fn14) preserves the filtration barrier and ameliorates lupus nephritis. J Am Soc Nephrol (2014) 0.93
A Role for Tubular Necroptosis in Cisplatin-Induced AKI. J Am Soc Nephrol (2015) 0.93
BASP1 promotes apoptosis in diabetic nephropathy. J Am Soc Nephrol (2010) 0.92
TWEAK and the progression of renal disease: clinical translation. Nephrol Dial Transplant (2014) 0.91
A nanoconjugate Apaf-1 inhibitor protects mesothelial cells from cytokine-induced injury. PLoS One (2009) 0.89
The role of aldosterone blockade in murine lupus nephritis. Arthritis Res Ther (2008) 0.88
TWEAK/Fn14 Axis: A Promising Target for the Treatment of Cardiovascular Diseases. Front Immunol (2014) 0.87
Soluble TWEAK independently predicts atherosclerosis in renal transplant patients. BMC Nephrol (2013) 0.86
Osteoprotegerin in exosome-like vesicles from human cultured tubular cells and urine. PLoS One (2013) 0.85
TWEAK/Fn14 and Non-Canonical NF-kappaB Signaling in Kidney Disease. Front Immunol (2013) 0.85
Inflammatory cytokines and survival factors from serum modulate tweak-induced apoptosis in PC-3 prostate cancer cells. PLoS One (2012) 0.83
Regulation of fibroblast growth factor-inducible 14 (Fn14) expression levels via ligand-independent lysosomal degradation. J Biol Chem (2014) 0.82
Albumin-induced apoptosis of tubular cells is modulated by BASP1. Cell Death Dis (2015) 0.82
A polymeric nanomedicine diminishes inflammatory events in renal tubular cells. PLoS One (2013) 0.80
Tumor necrosis factor-like weak inducer of apoptosis and its potential roles in lupus nephritis. Inflamm Res (2012) 0.79
TWEAK-Fn14 as a mediator of acute kidney injury. Kidney Int (2011) 0.79
The long noncoding RNA landscape in hypoxic and inflammatory renal epithelial injury. Am J Physiol Renal Physiol (2015) 0.78
Histone lysine crotonylation during acute kidney injury in mice. Dis Model Mech (2016) 0.78
Soluble Fn14 Is Detected and Elevated in Mouse and Human Kidney Disease. PLoS One (2016) 0.78
TWEAK/Fn14 system and crescent formation in IgA nephropathy. BMC Nephrol (2015) 0.77
NF-κB in inflammation and renal diseases. Cell Biosci (2015) 0.77
Deferasirox-induced iron depletion promotes BclxL downregulation and death of proximal tubular cells. Sci Rep (2017) 0.75
The role of tumor necrosis factor-like weak inducer of apoptosis in atherosclerosis via its two different receptors. Exp Ther Med (2017) 0.75
A novel TNF receptor family member binds TWEAK and is implicated in angiogenesis. Immunity (2001) 2.16
A Staphylococcus aureus capsular polysaccharide (CP) vaccine and CP-specific antibodies protect mice against bacterial challenge. Infect Immun (1996) 2.13
Angiotensin II activates nuclear transcription factor kappaB through AT(1) and AT(2) in vascular smooth muscle cells: molecular mechanisms. Circ Res (2000) 2.12
Transcription factor-kappa B (NF-kappa B) and renal disease. Kidney Int (2001) 2.10
Membrane fusion activity of tick-borne encephalitis virus and recombinant subviral particles in a liposomal model system. Virology (2000) 2.09
The novel Cer-like protein Caronte mediates the establishment of embryonic left-right asymmetry. Nature (1999) 2.08
Changes in monoamine concentrations in mouse brain associated with ethanol dependence and withdrawal. Br J Pharmacol (1974) 1.94
Angiotensin II and renal fibrosis. Hypertension (2001) 1.87
Involvement of tumor necrosis factor and platelet-activating factor in the pathogenesis of experimental nephrosis in rats. Lab Invest (1994) 1.84
Identification by targeted differential display of an immediate early gene encoding a putative serine/threonine kinase. J Biol Chem (1995) 1.80
Glucosamine inhibits IL-1beta-induced NFkappaB activation in human osteoarthritic chondrocytes. Osteoarthritis Cartilage (2003) 1.79
IgA glomerulonephritis (Berger's disease): evidence of high serum levels of polymeric IgA. Clin Exp Immunol (1980) 1.75
Characterization of cry genes in a Mexican Bacillus thuringiensis strain collection. Appl Environ Microbiol (1998) 1.74
The Fn14 immediate-early response gene is induced during liver regeneration and highly expressed in both human and murine hepatocellular carcinomas. Am J Pathol (2000) 1.73
Role of the renin-angiotensin system in vascular diseases: expanding the field. Hypertension (2001) 1.72
Derivation of protein-specific pair potentials based on weak sequence fragment similarity. Proteins (2000) 1.63
Riboflavin uptake by human-derived colonic epithelial NCM460 cells. Am J Physiol Cell Physiol (2000) 1.59
Molecular mechanism of the intestinal biotin transport process. Am J Physiol (1999) 1.59
Microfungal "weeds" in the leafcutter ant symbiosis. Microb Ecol (2008) 1.55
PCR analysis of the cryI insecticidal crystal family genes from Bacillus thuringiensis. Appl Environ Microbiol (1994) 1.55
Accumulation and decay of DG42 gene products follow a gradient pattern during Xenopus embryogenesis. Dev Biol (1988) 1.53
The mitogen-inducible Fn14 gene encodes a type I transmembrane protein that modulates fibroblast adhesion and migration. J Biol Chem (1999) 1.53
Red wine intake prevents nuclear factor-kappaB activation in peripheral blood mononuclear cells of healthy volunteers during postprandial lipemia. Circulation (2000) 1.51
Factors involved in the return of peristalsis in patients with achalasia of the cardia after Heller's myotomy. Am J Gastroenterol (1995) 1.50
Mycophenolate mofetil prevents salt-sensitive hypertension resulting from angiotensin II exposure. Kidney Int (2001) 1.50
Stage-specific keratins in Xenopus laevis embryos and tadpoles: the XK81 gene family. J Cell Biol (1986) 1.47
HMG-CoA reductase inhibition by atorvastatin reduces neointimal inflammation in a rabbit model of atherosclerosis. J Am Coll Cardiol (1998) 1.45
Losartan improves resistance artery lesions and prevents CTGF and TGF-beta production in mild hypertensive patients. Kidney Int (2006) 1.45
Stool losses and acidosis in diarrheal disease of infancy. Pediatrics (1965) 1.43
Targeting acute ischemic stroke with a calcium-sensitive opener of maxi-K potassium channels. Nat Med (2001) 1.43
Mycophenolate mofetil prevents salt-sensitive hypertension resulting from nitric oxide synthesis inhibition. Am J Physiol Renal Physiol (2001) 1.42
Angiotensin II participates in mononuclear cell recruitment in experimental immune complex nephritis through nuclear factor-kappa B activation and monocyte chemoattractant protein-1 synthesis. J Immunol (1998) 1.41
A method for the induction of dependence to ethanol in mice. Br J Pharmacol (1973) 1.41
Insulin-like growth factor I - a novel biomarker of abdominal aortic aneurysms. Eur J Vasc Endovasc Surg (2011) 1.40
Familial hypomagnesemia with hypercalciuria and nephrocalcinosis. Kidney Int (1995) 1.40
Cefazolin-induced encephalopathy in uremic patients. Rev Infect Dis (1991) 1.39
[Developing a Clinical Performance Measures System for hemodialysis, Quality Group, Spanish Society of Nephrology]. Nefrologia (2007) 1.39
[Hepatitis C virus and cryoglobulinemia]. Rev Clin Esp (1992) 1.39
Vascular actions of synthetic PAF-acether (a synthetic platelet-activating factor) in the rat: evidence for a platelet independent mechanism. Immunopharmacology (1982) 1.39
Familial IgA nephropathy associated with bilateral sensorineural deafness. Am J Kidney Dis (1992) 1.39
Severe hypoproteinemia and edema in association with varicella infection. Clin Pediatr (Phila) (1991) 1.38
Detection of monomeric and polymeric IgA containing immune complexes in serum and kidney from patients with alcoholic liver disease. Clin Exp Immunol (1982) 1.35
Immune complexes in IgA nephropathy: presence of antibodies against diet antigens and delayed clearance of specific polymeric IgA immune complexes. Clin Exp Immunol (1983) 1.34
Atorvastatin reduces NF-kappaB activation and chemokine expression in vascular smooth muscle cells and mononuclear cells. Atherosclerosis (1999) 1.34
Membrane fusion activity of the influenza virus hemagglutinin: interaction of HA2 N-terminal peptides with phospholipid vesicles. Biochemistry (1991) 1.33
T-cell dysfunctions in IgA nephropathy: specific abnormalities in the regulation of IgA synthesis. Clin Immunol Immunopathol (1983) 1.32
A delayed-early gene activated by fibroblast growth factor-1 encodes a protein related to aldose reductase. J Biol Chem (1994) 1.32
3-Hydroxy-3-methylglutaryl coenzyme a reductase and isoprenylation inhibitors induce apoptosis of vascular smooth muscle cells in culture. Circ Res (1998) 1.31
Evaluation of viral membrane fusion assays. Comparison of the octadecylrhodamine dequenching assay with the pyrene excimer assay. Biochemistry (1993) 1.31
Proinflammatory actions of angiotensins. Curr Opin Nephrol Hypertens (2001) 1.30
Pseudomonas exotoxin-mediated selection yields cells with altered expression of low-density lipoprotein receptor-related protein. J Cell Biol (1995) 1.29
Developmentally regulated cytokeratin gene in Xenopus laevis. Mol Cell Biol (1985) 1.29
A possible common pathogenesis of the mesangial IgA glomerulonephritis in patients with Berger's disease and Schönlein-Henoch syndrome. Proc Eur Dial Transplant Assoc (1980) 1.26
Unusual perforated appendicitis within umbilical hernia: CT findings. Abdom Imaging (2006) 1.26
Serum medroxyprogesterone acetate (MPA) concentrations and ovarian function following intramuscular injection of depo-MPA. J Clin Endocrinol Metab (1977) 1.25
Soluble IgA and IgG aggregates are catabolized by cultured rat mesangial cells and induce production of TNF-alpha and IL-6, and proliferation. J Immunol (1994) 1.23
Renal cell apoptosis induced by nephrotoxic drugs: cellular and molecular mechanisms and potential approaches to modulation. Apoptosis (2008) 1.22
Distinct patterns of expression of fibroblast growth factors and their receptors in human atheroma and nonatherosclerotic arteries. Association of acidic FGF with plaque microvessels and macrophages. J Clin Invest (1993) 1.20
Adaptive regulation of intestinal folate uptake: effect of dietary folate deficiency. Am J Physiol Cell Physiol (2000) 1.18
Histopathological correlation of cartilage swelling detected by magnetic resonance imaging in early experimental osteoarthritis. Osteoarthritis Cartilage (2004) 1.18
Expression of apoptosis regulatory proteins in tubular epithelium stressed in culture or following acute renal failure. Kidney Int (2000) 1.17
Increased rates of polymeric IgA synthesis by circulating lymphoid cells in IgA mesangial glomerulonephritis. Clin Exp Immunol (1982) 1.15
Effectiveness of a written clinical pathway for enhanced recovery after transthoracic (Ivor Lewis) oesophagectomy. Br J Surg (2010) 1.14
Immunological abnormalities in the tonsils of patients with IgA nephropathy: inversion in the ratio of IgA: IgG bearing lymphocytes and increased polymeric IgA synthesis. Clin Exp Immunol (1984) 1.13
Myocardial fibrosis and apoptosis, but not inflammation, are present in long-term experimental diabetes. Am J Physiol Heart Circ Physiol (2009) 1.13
Proapoptotic Fas ligand is expressed by normal kidney tubular epithelium and injured glomeruli. J Am Soc Nephrol (2000) 1.12
Tubular NF-kappaB and AP-1 activation in human proteinuric renal disease. Kidney Int (2001) 1.12
Studies on infant diarrhea. I. A comparison of the effects of milk feeding and intravenous therapy upon the composition and volume of the stool and urine. J Clin Invest (1966) 1.12
Potential role of nuclear factor κB in diabetic cardiomyopathy. Mediators Inflamm (2011) 1.12
Systemic infusion of angiotensin II into normal rats activates nuclear factor-kappaB and AP-1 in the kidney: role of AT(1) and AT(2) receptors. Am J Pathol (2001) 1.12
High-resolution MRI detects cartilage swelling at the early stages of experimental osteoarthritis. Osteoarthritis Cartilage (2001) 1.11
Value of helical computed tomography in the management of upper esophageal foreign bodies. Acta Radiol (2004) 1.11
Evidence for the involvement of IgE-basophil system in acute serum sickness. Clin Exp Immunol (1976) 1.10
Acquired eventration of the diaphragm: a complication of chest tube placement in neonatal pneumothorax. Pediatrics (1981) 1.10
Hypertrophic cardiomyopathy caused by a novel alpha-tropomyosin mutation (V95A) is associated with mild cardiac phenotype, abnormal calcium binding to troponin, abnormal myosin cycling, and poor prognosis. Circulation (2001) 1.09
Constitutive endothelin-1 overexpression promotes smooth muscle cell proliferation via an external autocrine loop. J Biol Chem (1994) 1.08
Angiotensin II modulates cell growth-related events and synthesis of matrix proteins in renal interstitial fibroblasts. Kidney Int (1997) 1.08
Overexpression of chemokines, fibrogenic cytokines, and myofibroblasts in human membranous nephropathy. Kidney Int (2000) 1.08
Vasoactive hormones and renal sclerosis. Kidney Int (1996) 1.07
Effects and interactions of endothelin-1 and angiotensin II on matrix protein expression and synthesis and mesangial cell growth. Hypertension (1996) 1.07
Effect of endothelin-1 on neutrophil adhesion to endothelial cells and perfused heart. Circulation (1993) 1.06
Morphological and biochemical observations on cells derived from the in vitro differentiation of the embryonal carcinoma cell line PCC4-F. Cancer Res (1977) 1.06
In situ non-radioactive detection of nuclear factors in paraffin sections by Southwestern histochemistry. Kidney Int (1999) 1.04
Receptors for immune complexes activate gene expression and synthesis of matrix proteins in cultured rat and human mesangial cells: role of TGF-beta. J Immunol (1996) 1.04
Transport of thiamine in human intestine: mechanism and regulation in intestinal epithelial cell model Caco-2. Am J Physiol (1999) 1.03
Biotin uptake by human colonic epithelial NCM460 cells: a carrier-mediated process shared with pantothenic acid. Am J Physiol (1998) 1.03
How to support forest management in a world of change: results of some regional studies. Environ Manage (2009) 1.02
Evaluation of the magnitude of gastro-oesophageal reflux in Barrett's oesophagus. Gut (1990) 1.02
Atorvastatin reduces the expression of cyclooxygenase-2 in a rabbit model of atherosclerosis and in cultured vascular smooth muscle cells. Atherosclerosis (2002) 1.01
Expression and phosphorylation of fibroblast-growth-factor-inducible kinase (Fnk) during cell-cycle progression. Biochem J (1998) 1.01