Published in Biken J on March 01, 1976
Enhancement of nonspecific immunity to Klebsiella pneumoniae infection by a synthetic immunoadjuvant (N-acetylmuramyl-L-alanyl-D-isoglutamine) and several analogs. Proc Natl Acad Sci U S A (1977) 3.31
Stimulation of the reticuloendothelial system of mice by muramyl dipeptide. Infect Immun (1979) 1.84
Biological activity of a new synthetic muramyl peptide adjuvant devoid of pyrogenicity. Infect Immun (1982) 1.73
Enhancement of the neonate's nonspecific immunity to Klebsiella infection by muramyl dipeptide, a synthetic immunoadjuvant. Proc Natl Acad Sci U S A (1978) 1.66
Sleep-promoting effects of muramyl peptides. Proc Natl Acad Sci U S A (1982) 1.46
Immunostimulant activities of a lipophilic muramyl dipeptide derivative and of desmuramyl peptidolipid analogs. Infect Immun (1980) 1.21
Adjuvant activity of synthetic 6-O-"mycoloyl"-N-acetylmuramyl-L-alanyl-D-isoglutamine and related compounds. Infect Immun (1978) 1.15
Epithelioid granuloma formation by a synthetic bacterial cell wall component, muramyl dipeptide (MDP). Am J Pathol (1980) 1.14
Stimulation of nonspecific resistance to infection induced by 6-O-acyl muramyl dipeptide analogs in mice. Infect Immun (1981) 1.12
Necrotic inflammatory reaction induced by muramyl dipeptide in guinea pigs sensitized by tubercle bacilli. J Exp Med (1985) 1.07
Endogenous pyrogen production by human blood monocytes stimulated by staphylococcal cell wall components. Infect Immun (1981) 1.04
Adjuvant activity of N-acetyl muramyl dipeptides for the induction of delayed-type hypersensitivity to azobenzenearsonate-N-acetyl-L-tyrosine in guinea pigs. Infect Immun (1980) 1.01
Muramyl peptides. Variation of somnogenic activity with structure. J Exp Med (1984) 0.99
Two adjuvant-active muramyl dipeptide analogs induce differential production of lymphocyte-activating factor and a factor causing distress in guinea pigs. Infect Immun (1984) 0.95
Gut flora induces and maintains resistance against streptococcal cell wall-induced arthritis in F344 rats. Clin Exp Immunol (1992) 0.94
Role of thymus for N-acetyl muramyl-L-alanyl-D-isoglutamine-induced polyarthritis and granuloma formation in euthymic and athymic nude rats or in neonatally thymectomized rats. Infect Immun (1981) 0.94
Adjuvant activity of 6-O-mycoloyl derivatives of N-acetylmuramyl-L-seryl-D-isoglutamine and related compounds in mice and guinea pigs. Infect Immun (1979) 0.91
Uveitis induction in the rabbit by muramyl dipeptides. Infect Immun (1986) 0.89
Comparison of immunomodulatory activities in mice and guinea pigs of a synthetic desmuramyl peptidolipid triglymyc. Infect Immun (1984) 0.85
Structural requirements of muramylpeptides for induction of necrosis at sites primed with Mycobacterium tuberculosis in guinea pigs. Infect Immun (1987) 0.84
Stimulatory effect of N-acetyl Muramyl dipeptide in vivo: proliferation of bone marrow progenitor cells in mice. Infect Immun (1982) 0.84
Stimulation of cell-mediated immunity by bestatin correlates with reduction of bacterial persistence in experimental chronic Salmonella typhimurium infection. Infect Immun (1984) 0.81
Analgesic effects of N-acetylmuramyl-L-alanyl-D-isoglutamine in decreasing the acetic acid-induced abdominal-writhing response. Infect Immun (1987) 0.80
Human NOD2 Recognizes Structurally Unique Muramyl Dipeptides from Mycobacterium leprae. Infect Immun (2016) 0.76
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature (2002) 28.79
Whole genome sequencing of meticillin-resistant Staphylococcus aureus. Lancet (2001) 18.55
Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and genomic comparison with a laboratory strain K-12. DNA Res (2001) 15.22
Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin. Nature (1986) 9.63
In vitro and in vivo antibacterial activity of T-1220, a new semisynthetic penicillin. Antimicrob Agents Chemother (1977) 7.35
Congenital bile duct cysts: Classification, operative procedures, and review of thirty-seven cases including cancer arising from choledochal cyst. Am J Surg (1977) 7.08
Hepatitis C virus infection is associated with the development of hepatocellular carcinoma. Proc Natl Acad Sci U S A (1990) 6.96
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites. Proc Natl Acad Sci U S A (2001) 4.56
Endovascular stent-graft placement for the treatment of acute aortic dissection. N Engl J Med (1999) 4.33
Clinically mild encephalitis/encephalopathy with a reversible splenial lesion. Neurology (2004) 4.24
Regulation of transcription of the Reovirus genome. J Mol Biol (1968) 3.85
Sterol regulatory element-binding protein-1 as a key transcription factor for nutritional induction of lipogenic enzyme genes. J Biol Chem (1999) 3.72
Immunoadjuvant activities of synthetic N-acetyl-muramyl-peptides or -amino acids. Biken J (1975) 3.69
Structure and expression of human B cell stimulatory factor-2 (BSF-2/IL-6) gene. EMBO J (1987) 3.64
A yeast mitogen-activated protein kinase homolog (Mpk1p) mediates signalling by protein kinase C. Mol Cell Biol (1993) 3.47
Schizosaccharomyces pombe ste11+ encodes a transcription factor with an HMG motif that is a critical regulator of sexual development. Genes Dev (1991) 3.26
Calcium movements, distribution, and functions in smooth muscle. Pharmacol Rev (1997) 3.23
In vitro and in vivo activities of anti-influenza virus compound T-705. Antimicrob Agents Chemother (2002) 3.17
Promoter analysis of the mouse sterol regulatory element-binding protein-1c gene. J Biol Chem (2000) 3.11
Retrovirus-like particles containing RNA homologous to the transposable element copia in Drosophila melanogaster. Nature (1983) 3.07
Protein kinase C phosphorylates the inhibitory guanine-nucleotide-binding regulatory component and apparently suppresses its function in hormonal inhibition of adenylate cyclase. Eur J Biochem (1985) 3.04
Intravenous infusion of immortalized human mesenchymal stem cells protects against injury in a cerebral ischemia model in adult rat. Exp Neurol (2005) 2.97
Fission yeast Taz1 protein is required for meiotic telomere clustering and recombination. Nature (1998) 2.95
In vitro and in vivo antimicrobial activities of T-3811ME, a novel des-F(6)-quinolone. Antimicrob Agents Chemother (1999) 2.88
Selective inhibition of reovirus ribonucleic acid synthesis by cycloheximide. J Virol (1967) 2.84
Function of the 30 kd protein of tobacco mosaic virus: involvement in cell-to-cell movement and dispensability for replication. EMBO J (1987) 2.78
Nucleotide sequence of core and envelope genes of the hepatitis C virus genome derived directly from human healthy carriers. Nucleic Acids Res (1990) 2.76
Escherichia coli RuvC protein is an endonuclease that resolves the Holliday structure. EMBO J (1991) 2.76
Identification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein 1c gene promoter. Mol Cell Biol (2001) 2.68
Defective virions of reovirus. J Virol (1970) 2.68
Anti-oncogenic and oncogenic potentials of interferon regulatory factors-1 and -2. Science (1993) 2.63
Structure and expression of a cloned cDNA for mouse interferon-beta. J Biol Chem (1983) 2.61
Heat-inactivated proteins are rescued by the DnaK.J-GrpE set and ClpB chaperones. Proc Natl Acad Sci U S A (1999) 2.54
Structural units of reovirus ribonucleic acid and their possible functional significance. J Virol (1967) 2.54
Association between a large plasmid and 15- to 17-kilodalton antigens in virulent Rhodococcus equi. Infect Immun (1991) 2.52
Cell cycle-dependent expression and spindle pole localization of a novel human protein kinase, Aik, related to Aurora of Drosophila and yeast Ipl1. J Biol Chem (1997) 2.44
Hepatic uptake of chylomicron remnants in WHHL rabbits: a mechanism genetically distinct from the low density lipoprotein receptor. Proc Natl Acad Sci U S A (1982) 2.43
Prevention of lung reperfusion injury in rabbits by a monoclonal antibody against interleukin-8. Nature (1993) 2.38
Metapyrocatechase. 3. Substrate specificity and mode of ring fission. Biochim Biophys Acta (1970) 2.32
Increased responsiveness of left ventricular apical myocardium to adrenergic stimuli. Cardiovasc Res (1993) 2.31
Magnetic resonance mapping demonstrates benefits of VEGF-induced myocardial angiogenesis. Nat Med (1995) 2.29
The nucleotide sequences of copia and copia-related RNA in Drosophila virus-like particles. Nature (1985) 2.23
Ventricular fibrillation. A possible mechanism of sudden death in patients and Wolff-Parkinson-White syndrome. Circulation (1971) 2.23
Serial inbreeding of rabbits with hereditary hyperlipidemia (WHHL-rabbit). Atherosclerosis (1980) 2.18
Deletion of IRF-1, mapping to chromosome 5q31.1, in human leukemia and preleukemic myelodysplasia. Science (1993) 2.17
Comparison of whole genome sequences of Chlamydia pneumoniae J138 from Japan and CWL029 from USA. Nucleic Acids Res (2000) 2.16
Activation of the Keap1/Nrf2 pathway for neuroprotection by electrophilic [correction of electrophillic] phase II inducers. Proc Natl Acad Sci U S A (2006) 2.15
Deficiency of low density lipoprotein receptors in liver and adrenal gland of the WHHL rabbit, an animal model of familial hypercholesterolemia. Proc Natl Acad Sci U S A (1981) 2.08
Feasibility of ultrasound cataract surgery with a 1.4 mm incision. J Cataract Refract Surg (2001) 2.07
Accuracy of assessment of cardiac vagal tone by heart rate variability in normal subjects. Am J Cardiol (1991) 2.07
Receptor-dependent and receptor-independent degradation of low density lipoprotein in normal rabbits and in receptor-deficient mutant rabbits. J Biol Chem (1982) 2.06
The gene for a major exopolyphosphatase of Saccharomyces cerevisiae. J Bacteriol (1995) 2.06
Synthetic lipid A with endotoxic and related biological activities comparable to those of a natural lipid A from an Escherichia coli re-mutant. Infect Immun (1985) 2.04
An informative linkage map of soybean reveals QTLs for flowering time, leaflet morphology and regions of segregation distortion. DNA Res (2001) 2.03
Structural analysis of repetitive DNA sequences in the bovine corticotropin-beta-lipotropin precursor gene region. Nucleic Acids Res (1982) 1.99
Temporary inhalation anaesthesia in experimental pigs. Lab Anim (2009) 1.98
Impaired receptor-mediated catabolism of low density lipoprotein in the WHHL rabbit, an animal model of familial hypercholesterolemia. Proc Natl Acad Sci U S A (1982) 1.98
Cloning of the pka1 gene encoding the catalytic subunit of the cAMP-dependent protein kinase in Schizosaccharomyces pombe. J Biol Chem (1994) 1.97
The Schizosaccharomyces pombe mei4+ gene encodes a meiosis-specific transcription factor containing a forkhead DNA-binding domain. Mol Cell Biol (1998) 1.97
Dissecting aneurysms of the intracranial vertebral artery. J Neurosurg (1990) 1.95
Protective antigens from El Tor vibrios. 1. The preparation and properties of a purified protective antigen from an El Tor vibrio (Ogawa subtype). Bull World Health Organ (1965) 1.95
The SPIRAL genes are required for directional control of cell elongation in Aarabidopsis thaliana. Development (2000) 1.95
Efficacy of FK463, a new lipopeptide antifungal agent, in mouse models of disseminated candidiasis and aspergillosis. Antimicrob Agents Chemother (2000) 1.93
Schizosaccharomyces pombe gad7+ encodes a phosphoprotein with a bZIP domain, which is required for proper G1 arrest and gene expression under nitrogen starvation. Genes Cells (1996) 1.93
Expression of processed core protein of hepatitis C virus in mammalian cells. J Virol (1991) 1.91
Genetic analysis of the peptide synthetase genes for a cyclic heptapeptide microcystin in Microcystis spp. J Biochem (1999) 1.91
Inhibition of macrophage migration by muramyl peptides. Infect Immun (1979) 1.91
JSAP1, a novel jun N-terminal protein kinase (JNK)-binding protein that functions as a Scaffold factor in the JNK signaling pathway. Mol Cell Biol (1999) 1.90
Activation of Cdh1-dependent APC is required for G1 cell cycle arrest and DNA damage-induced G2 checkpoint in vertebrate cells. EMBO J (2001) 1.88
Metapyrocatechase. II. The role of iron and sulfhydryl groups. J Biol Chem (1968) 1.87
WFS1 (Wolfram syndrome 1) gene product: predominant subcellular localization to endoplasmic reticulum in cultured cells and neuronal expression in rat brain. Hum Mol Genet (2001) 1.86
VEGF and VEGF type C play an important role in angiogenesis and lymphangiogenesis in human malignant mesothelioma tumours. Br J Cancer (1999) 1.86
Carcinoma arising in the wall of congenital bile duct cysts. Cancer (1979) 1.86
Aberrant promoter methylation profile of bladder cancer and its relationship to clinicopathological features. Cancer Res (2001) 1.84
In situ analysis of nitrifying biofilms as determined by in situ hybridization and the use of microelectrodes. Appl Environ Microbiol (1999) 1.84
Stimulation of the reticuloendothelial system of mice by muramyl dipeptide. Infect Immun (1979) 1.84
Ongoing prospective study of segmentectomy for small lung tumors. Study Group of Extended Segmentectomy for Small Lung Tumor. Ann Thorac Surg (1998) 1.83
Specificity in transcription of the reovirus genome. Proc Natl Acad Sci U S A (1967) 1.83
Polyketide synthase gene coupled to the peptide synthetase module involved in the biosynthesis of the cyclic heptapeptide microcystin. J Biochem (2000) 1.81
Frequent epigenetic inactivation of SFRP genes and constitutive activation of Wnt signaling in gastric cancer. Oncogene (2007) 1.81
Laparoscopic partial hepatectomy and left lateral segmentectomy: technique and results of a clinical series. Surgery (1996) 1.79
Unusual priming mechanism of RNA-directed DNA synthesis in copia retrovirus-like particles of Drosophila. Nature (1986) 1.79
Troglitazone inhibits atherosclerosis in apolipoprotein E-knockout mice: pleiotropic effects on CD36 expression and HDL. Arterioscler Thromb Vasc Biol (2001) 1.78
Isolation of a possible fourth group of RNA phage. Jpn J Microbiol (1968) 1.78
Structural requirements for arthritogenicity of peptidoglycans from Staphylococcus aureus and Lactobacillus plant arum and analogous synthetic compounds. J Immunol (1976) 1.76
Purification, characterization, and cDNA structure of isoamylase from developing endosperm of rice. Planta (1999) 1.75
Uncoupling of the cytochrome P-450cam monooxygenase reaction by a single mutation, threonine-252 to alanine or valine: possible role of the hydroxy amino acid in oxygen activation. Proc Natl Acad Sci U S A (1989) 1.75
Structure and regulation of the human interferon regulatory factor 1 (IRF-1) and IRF-2 genes: implications for a gene network in the interferon system. Mol Cell Biol (1994) 1.74
Hepatic 'stem cell' malignancies in adults: four cases. Histopathology (2003) 1.73
Construction of a genetic linkage map of the model legume Lotus japonicus using an intraspecific F2 population. DNA Res (2001) 1.72
Chemical modification of erythromycins. I. Synthesis and antibacterial activity of 6-O-methylerythromycins A. J Antibiot (Tokyo) (1984) 1.71
Requirement of dendritic cells and B cells in the clonal deletion of Mls-reactive T cells in the thymus. J Exp Med (1991) 1.71
Carcinoma related to choledochal cysts with internal drainage operations. Surg Gynecol Obstet (1987) 1.70