Published in Br J Cancer on September 01, 1999
Vascular endothelial growth factor-C-mediated lymphangiogenesis promotes tumour metastasis. EMBO J (2001) 4.70
Concurrent induction of lymphangiogenesis, angiogenesis, and macrophage recruitment by vascular endothelial growth factor-C in melanoma. Am J Pathol (2001) 2.89
Prognostic factors for malignant mesothelioma in 142 patients: validation of CALGB and EORTC prognostic scoring systems. Thorax (2000) 2.83
Blockade of vascular endothelial growth factor receptor-3 signaling inhibits fibroblast growth factor-2-induced lymphangiogenesis in mouse cornea. Proc Natl Acad Sci U S A (2002) 2.30
Vascular endothelial growth factor-C (VEGF-C) expression in human colorectal cancer tissues. Br J Cancer (2000) 1.67
Angiogenesis in cancer. Vasc Health Risk Manag (2006) 1.49
Multicenter, double-blind, placebo-controlled, randomized phase II trial of gemcitabine/cisplatin plus bevacizumab or placebo in patients with malignant mesothelioma. J Clin Oncol (2012) 1.37
VEGF-A, VEGF-C, and VEGF-D in colorectal cancer progression. Neoplasia (2001) 1.37
Hypoxia-inducible factor 1-dependent expression of platelet-derived growth factor B promotes lymphatic metastasis of hypoxic breast cancer cells. Proc Natl Acad Sci U S A (2012) 1.27
New and emerging therapeutic options for malignant pleural mesothelioma: review of early clinical trials. Cancer Manag Res (2015) 1.19
Vascular endothelial growth factor-D is an independent prognostic factor in epithelial ovarian carcinoma. Br J Cancer (2003) 1.18
Lymphatic vessels as targets of tumor therapy? J Exp Med (2001) 1.17
MicroRNA-1826 targets VEGFC, beta-catenin (CTNNB1) and MEK1 (MAP2K1) in human bladder cancer. Carcinogenesis (2011) 1.16
The expression of vascular endothelial growth factor C and its receptors in non-small cell lung cancer. Br J Cancer (2001) 1.16
Role of VEGF-C and VEGF-D in lymphangiogenesis in gastric cancer. Int J Clin Oncol (2005) 1.11
Tumor stroma as targets for cancer therapy. Pharmacol Ther (2012) 1.06
Vascular endothelial growth factor-C expression and its relationship to pelvic lymph node status in invasive cervical cancer. Br J Cancer (2001) 1.05
Expression and significance of VEGF-C and FLT-4 in gastric cancer. World J Gastroenterol (2004) 1.04
A phase II study of sorafenib in malignant mesothelioma: results of Cancer and Leukemia Group B 30307. J Thorac Oncol (2010) 1.02
Targeted inhibition of multiple receptor tyrosine kinases in mesothelioma. Neoplasia (2011) 0.98
Genome-wide profile of pleural mesothelioma versus parietal and visceral pleura: the emerging gene portrait of the mesothelioma phenotype. PLoS One (2009) 0.96
Methionine aminopeptidase-2 regulates human mesothelioma cell survival: role of Bcl-2 expression and telomerase activity. Am J Pathol (2001) 0.95
Lymph node dissection in primary intrahepatic malignant mesothelioma: case report and implications for diagnosis and therapy. Langenbecks Arch Surg (2009) 0.93
Biomarkers and prognostic factors for mesothelioma. Ann Cardiothorac Surg (2012) 0.93
Vatalanib in malignant mesothelioma: a phase II trial by the Cancer and Leukemia Group B (CALGB 30107). Lung Cancer (2011) 0.92
Angiogenesis is an independent prognostic factor in malignant mesothelioma. Br J Cancer (2001) 0.92
Phase II study of cediranib in patients with malignant pleural mesothelioma: SWOG S0509. J Thorac Oncol (2011) 0.91
Phase II testing of sunitinib: the National Cancer Institute of Canada Clinical Trials Group IND Program Trials IND.182-185. Curr Oncol (2007) 0.90
Expression of vascular endothelial growth factor-C and angiogenesis in esophageal squamous cell carcinoma. World J Gastroenterol (2006) 0.89
Matrix metalloproteinases 2 and 9 (gelatinases A and B) expression in malignant mesothelioma and benign pleura. Br J Cancer (2003) 0.89
Novel therapies in phase II and III trials for malignant pleural mesothelioma. J Natl Compr Canc Netw (2012) 0.87
Resveratrol and arsenic trioxide act synergistically to kill tumor cells in vitro and in vivo. PLoS One (2014) 0.83
Expression of the VEGF and angiopoietin genes in endometrial atypical hyperplasia and endometrial cancer. Br J Cancer (2003) 0.79
Clinicopathological significance of lymphangiogenesis detected by immunohistochemistry using D2-40 monoclonal antibody in breast cancer. Fukushima J Med Sci (2016) 0.78
New insight into the molecular mechanisms of the biological effects of DNA minor groove binders. PLoS One (2011) 0.77
Expression of cancer-associated molecules in malignant mesothelioma. Biomark Insights (2007) 0.77
MDM2 and HIF1alpha expression levels in different histologic subtypes of malignant pleural mesothelioma: correlation with pathological and clinical data. Oncotarget (2015) 0.75
Pemetrexed Maintenance Therapy Following Bevacizumab-Containing First-Line Chemotherapy in Advanced Malignant Pleural Mesothelioma: A Case Report and Literatures Review. Medicine (Baltimore) (2016) 0.75
Identification of high-affinity VEGFR3-binding peptides through a phage-displayed random peptide library. J Gynecol Oncol (2015) 0.75
Spotlight on bevacizumab and its potential in the treatment of malignant pleural mesothelioma: the evidence to date. Onco Targets Ther (2017) 0.75
Progranulin and granulin-like protein as novel VEGF-independent angiogenic factors derived from human mesothelioma cells. Oncogene (2016) 0.75
Investigational approaches for mesothelioma. Front Oncol (2011) 0.75
The role of the cell-cell interactions in cancer progression. J Cell Mol Med (2015) 0.75
Usefulness of Aquaporin 1 as a Prognostic Marker in a Prospective Cohort of Malignant Mesotheliomas. Int J Mol Sci (2016) 0.75
Expression of vascular endothelial growth factor (VEGF)-C in preoperative biopsy specimens and metastatic foci of regional lymph nodes in submucosal gastric carcinoma. World J Surg Oncol (2005) 0.75
Recommended Readings from the University of Oxford Respiratory Trials Unit Research Fellows. Am J Respir Crit Care Med (2017) 0.75
A pilot study of zoledronic acid in the treatment of patients with advanced malignant pleural mesothelioma. Lung Cancer (Auckl) (2017) 0.75
Expression of the fms-like tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development. Proc Natl Acad Sci U S A (1995) 7.11
Hyperplasia of lymphatic vessels in VEGF-C transgenic mice. Science (1997) 6.37
A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases. EMBO J (1996) 5.33
Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer. Cancer Res (1995) 4.84
Relation of neovascularisation to metastasis of non-small-cell lung cancer. Lancet (1992) 3.77
VEGF-C receptor binding and pattern of expression with VEGFR-3 suggests a role in lymphatic vascular development. Development (1996) 2.82
Vascular endothelial growth factor-related protein: a ligand and specific activator of the tyrosine kinase receptor Flt4. Proc Natl Acad Sci U S A (1996) 2.77
Vascular endothelial growth factor B, a novel growth factor for endothelial cells. Proc Natl Acad Sci U S A (1996) 2.71
Molecular basis of different forms of metachromatic leukodystrophy. N Engl J Med (1991) 2.69
Expression of vascular endothelial growth factor and its possible relation with neovascularization in human brain tumors. Cancer Res (1995) 1.76
Association of vascular endothelial growth factor expression with tumor angiogenesis and with early relapse in primary breast cancer. Jpn J Cancer Res (1994) 1.75
Molecular cloning of a novel vascular endothelial growth factor, VEGF-D. Genomics (1997) 1.75
Endothelial cell phenotypic diversity. In situ demonstration of immunologic and enzymatic heterogeneity that correlates with specific morphologic subtypes. Am J Clin Pathol (1987) 1.59
Differential regulation and function of CD73, a glycosyl-phosphatidylinositol-linked 70-kD adhesion molecule, on lymphocytes and endothelial cells. J Cell Biol (1997) 1.46
Cloning and characterization of a novel human gene related to vascular endothelial growth factor. Genome Res (1996) 1.43
Mechanisms of carcinogenesis and clinical features of asbestos-associated cancers. Cancer Invest (1996) 1.37
Malignant fibrous histiocytoma tumor cells resemble fibroblasts. Am J Surg Pathol (1986) 1.28
Coexpression of flt-1, flt-4 and KDR in freshly isolated and cultured human endothelial cells. Biochem Biophys Res Commun (1996) 0.99
Evaluation of tumour angiogenesis as a prognostic marker in malignant mesothelioma. J Pathol (1997) 0.98
Angiogenic activity as a marker of neoplastic and preneoplastic lesions of the human bladder. Ann Surg (1980) 0.95
Activities of adenosine deaminase, 5'-nucleotidase, guanase, and cytidine deaminase enzymes in cancerous and non-cancerous human breast tissues. Breast Cancer Res Treat (1996) 0.94
Activity of the enzymes participating in purine metabolism of cancerous and noncancerous human kidney tissues. Cancer Invest (1997) 0.86
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature (2002) 28.79
Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin. Nature (1986) 9.63
In vitro and in vivo antibacterial activity of T-1220, a new semisynthetic penicillin. Antimicrob Agents Chemother (1977) 7.35
Congenital bile duct cysts: Classification, operative procedures, and review of thirty-seven cases including cancer arising from choledochal cyst. Am J Surg (1977) 7.08
Hepatitis C virus infection is associated with the development of hepatocellular carcinoma. Proc Natl Acad Sci U S A (1990) 6.96
Regulation of transcription of the Reovirus genome. J Mol Biol (1968) 3.85
Immunoadjuvant activities of synthetic N-acetyl-muramyl-peptides or -amino acids. Biken J (1975) 3.69
Structure and expression of human B cell stimulatory factor-2 (BSF-2/IL-6) gene. EMBO J (1987) 3.64
A yeast mitogen-activated protein kinase homolog (Mpk1p) mediates signalling by protein kinase C. Mol Cell Biol (1993) 3.47
Schizosaccharomyces pombe ste11+ encodes a transcription factor with an HMG motif that is a critical regulator of sexual development. Genes Dev (1991) 3.26
In vitro and in vivo activities of anti-influenza virus compound T-705. Antimicrob Agents Chemother (2002) 3.17
Protein kinase C phosphorylates the inhibitory guanine-nucleotide-binding regulatory component and apparently suppresses its function in hormonal inhibition of adenylate cyclase. Eur J Biochem (1985) 3.04
Fission yeast Taz1 protein is required for meiotic telomere clustering and recombination. Nature (1998) 2.95
In vitro and in vivo antimicrobial activities of T-3811ME, a novel des-F(6)-quinolone. Antimicrob Agents Chemother (1999) 2.88
Selective inhibition of reovirus ribonucleic acid synthesis by cycloheximide. J Virol (1967) 2.84
Function of the 30 kd protein of tobacco mosaic virus: involvement in cell-to-cell movement and dispensability for replication. EMBO J (1987) 2.78
Nucleotide sequence of core and envelope genes of the hepatitis C virus genome derived directly from human healthy carriers. Nucleic Acids Res (1990) 2.76
Defective virions of reovirus. J Virol (1970) 2.68
Structure and expression of a cloned cDNA for mouse interferon-beta. J Biol Chem (1983) 2.61
Heat-inactivated proteins are rescued by the DnaK.J-GrpE set and ClpB chaperones. Proc Natl Acad Sci U S A (1999) 2.54
Structural units of reovirus ribonucleic acid and their possible functional significance. J Virol (1967) 2.54
Association between a large plasmid and 15- to 17-kilodalton antigens in virulent Rhodococcus equi. Infect Immun (1991) 2.52
Risk of oral squamous cell carcinoma in 402 patients with oral lichen planus: a follow-up study in an Italian population. Oral Oncol (2004) 2.46
Hepatic uptake of chylomicron remnants in WHHL rabbits: a mechanism genetically distinct from the low density lipoprotein receptor. Proc Natl Acad Sci U S A (1982) 2.43
Prevention of lung reperfusion injury in rabbits by a monoclonal antibody against interleukin-8. Nature (1993) 2.38
Increased responsiveness of left ventricular apical myocardium to adrenergic stimuli. Cardiovasc Res (1993) 2.31
DNA replication control through interaction of E2F-RB and the origin recognition complex. Nat Cell Biol (2001) 2.24
Ventricular fibrillation. A possible mechanism of sudden death in patients and Wolff-Parkinson-White syndrome. Circulation (1971) 2.23
Simian virus 40-like DNA sequences in human pleural mesothelioma. Oncogene (1994) 2.21
Serial inbreeding of rabbits with hereditary hyperlipidemia (WHHL-rabbit). Atherosclerosis (1980) 2.18
Activation of the Keap1/Nrf2 pathway for neuroprotection by electrophilic [correction of electrophillic] phase II inducers. Proc Natl Acad Sci U S A (2006) 2.15
Deficiency of low density lipoprotein receptors in liver and adrenal gland of the WHHL rabbit, an animal model of familial hypercholesterolemia. Proc Natl Acad Sci U S A (1981) 2.08
Accuracy of assessment of cardiac vagal tone by heart rate variability in normal subjects. Am J Cardiol (1991) 2.07
Receptor-dependent and receptor-independent degradation of low density lipoprotein in normal rabbits and in receptor-deficient mutant rabbits. J Biol Chem (1982) 2.06
Ssn6-Tup1 interacts with class I histone deacetylases required for repression. Genes Dev (2000) 2.03
Simian virus-40 large-T antigen binds p53 in human mesotheliomas. Nat Med (1997) 2.01
Structural analysis of repetitive DNA sequences in the bovine corticotropin-beta-lipotropin precursor gene region. Nucleic Acids Res (1982) 1.99
Impaired receptor-mediated catabolism of low density lipoprotein in the WHHL rabbit, an animal model of familial hypercholesterolemia. Proc Natl Acad Sci U S A (1982) 1.98
Temporary inhalation anaesthesia in experimental pigs. Lab Anim (2009) 1.98
Cloning of the pka1 gene encoding the catalytic subunit of the cAMP-dependent protein kinase in Schizosaccharomyces pombe. J Biol Chem (1994) 1.97
The Schizosaccharomyces pombe mei4+ gene encodes a meiosis-specific transcription factor containing a forkhead DNA-binding domain. Mol Cell Biol (1998) 1.97
Dissecting aneurysms of the intracranial vertebral artery. J Neurosurg (1990) 1.95
Protective antigens from El Tor vibrios. 1. The preparation and properties of a purified protective antigen from an El Tor vibrio (Ogawa subtype). Bull World Health Organ (1965) 1.95
The SPIRAL genes are required for directional control of cell elongation in Aarabidopsis thaliana. Development (2000) 1.95
Genetic-susceptibility factor and malignant mesothelioma in the Cappadocian region of Turkey. Lancet (2001) 1.94
Efficacy of FK463, a new lipopeptide antifungal agent, in mouse models of disseminated candidiasis and aspergillosis. Antimicrob Agents Chemother (2000) 1.93
Metformin attenuates ovarian cancer cell growth in an AMP-kinase dispensable manner. J Cell Mol Med (2011) 1.93
Schizosaccharomyces pombe gad7+ encodes a phosphoprotein with a bZIP domain, which is required for proper G1 arrest and gene expression under nitrogen starvation. Genes Cells (1996) 1.93
Expression of processed core protein of hepatitis C virus in mammalian cells. J Virol (1991) 1.91
Human mesothelial cells are unusually susceptible to simian virus 40-mediated transformation and asbestos cocarcinogenicity. Proc Natl Acad Sci U S A (2000) 1.91
Correlation between the immunoadjuvant activities and pyrogenicities of synthetic N-acetylmuramyl-peptides or -amino acids. Biken J (1976) 1.91
WFS1 (Wolfram syndrome 1) gene product: predominant subcellular localization to endoplasmic reticulum in cultured cells and neuronal expression in rat brain. Hum Mol Genet (2001) 1.86
Kaposi's sarcoma causing pulmonary infiltrates and respiratory failure in the acquired immunodeficiency syndrome. Ann Intern Med (1985) 1.86
Carcinoma arising in the wall of congenital bile duct cysts. Cancer (1979) 1.86
In situ analysis of nitrifying biofilms as determined by in situ hybridization and the use of microelectrodes. Appl Environ Microbiol (1999) 1.84
Ongoing prospective study of segmentectomy for small lung tumors. Study Group of Extended Segmentectomy for Small Lung Tumor. Ann Thorac Surg (1998) 1.83
Specificity in transcription of the reovirus genome. Proc Natl Acad Sci U S A (1967) 1.83
Frequent epigenetic inactivation of SFRP genes and constitutive activation of Wnt signaling in gastric cancer. Oncogene (2007) 1.81
Intraoperative photodynamic therapy for malignant mesothelioma. Ann Thorac Surg (1990) 1.77
Structural requirements for arthritogenicity of peptidoglycans from Staphylococcus aureus and Lactobacillus plant arum and analogous synthetic compounds. J Immunol (1976) 1.76
Uncoupling of the cytochrome P-450cam monooxygenase reaction by a single mutation, threonine-252 to alanine or valine: possible role of the hydroxy amino acid in oxygen activation. Proc Natl Acad Sci U S A (1989) 1.75
The SV40 large T antigen and adenovirus E1a oncoproteins interact with distinct isoforms of the transcriptional co-activator, p300. EMBO J (1996) 1.75
Chemical modification of erythromycins. I. Synthesis and antibacterial activity of 6-O-methylerythromycins A. J Antibiot (Tokyo) (1984) 1.71
Overlapping roles for the histone acetyltransferase activities of SAGA and elongator in vivo. EMBO J (2000) 1.71
Requirement of dendritic cells and B cells in the clonal deletion of Mls-reactive T cells in the thymus. J Exp Med (1991) 1.71
Carcinoma related to choledochal cysts with internal drainage operations. Surg Gynecol Obstet (1987) 1.70
Treatment of hypertensive cerebellar hemorrhage--surgical or conservative management? Neurosurgery (1994) 1.70
The retinoblastoma gene family pRb/p105, p107, pRb2/p130 and simian virus-40 large T-antigen in human mesotheliomas. Nat Med (1997) 1.69
Virulence-associated 15- to 17-kilodalton antigens in Rhodococcus equi: temperature-dependent expression and location of the antigens. Infect Immun (1992) 1.69
Mechanism for elimination of a tumor suppressor: aberrant splicing of a brain-specific exon causes loss of function of Bin1 in melanoma. Proc Natl Acad Sci U S A (1999) 1.68
Localization of perforin in viral vesicles and erythema multiforme. Dermatology (1994) 1.68
Expression of processed envelope protein of hepatitis C virus in mammalian and insect cells. J Virol (1992) 1.68
Neurofibromatosis type 2 (NF2) gene is somatically mutated in mesothelioma but not in lung cancer. Cancer Res (1995) 1.67
Purification and properties of a polyvinyl alcohol-degrading enzyme produced by a strain of Pseudomonas. Arch Biochem Biophys (1976) 1.66
Flow capacities of arterial grafts for coronary artery bypass grafting. Ann Thorac Surg (1993) 1.65
New Ehrlichia species closely related to Ehrlichia chaffeensis isolated from Ixodes ovatus ticks in Japan. J Clin Microbiol (2000) 1.64
SV40 induces mesotheliomas in hamsters. Am J Pathol (1993) 1.64
Decreased magnitude of heart rate spectral components in coronary artery disease. Its relation to angiographic severity. Circulation (1990) 1.64
Surgical pathology of the lung in Wegener's granulomatosis. Review of 87 open lung biopsies from 67 patients. Am J Surg Pathol (1991) 1.63
Anatomy and etiology of extrahepatic portal vein obstruction in children leading to bleeding esophageal varices. J Am Coll Surg (1996) 1.63
Virulence-associated plasmids in Rhodococcus equi. J Clin Microbiol (1993) 1.63
Drosophila Cdk4 is required for normal growth and is dispensable for cell cycle progression. EMBO J (2000) 1.63
Carcinoma of the cystic duct associated with pancreaticobiliary maljunction. J Gastroenterol (2001) 1.61
Molecular interaction of CD1b with lipoglycan antigens. Immunity (1998) 1.60
Induction of pre-early nuclear antigen(s) in HEL cells infected with human cytomegalovirus. Microbiol Immunol (1979) 1.59
Mapping quantitative trait loci for proteinuria-induced renal collagen deposition. Kidney Int (2008) 1.58
Coexpression of microsomal-type prostaglandin E synthase with cyclooxygenase-2 in brain endothelial cells of rats during endotoxin-induced fever. J Neurosci (2001) 1.58
Results of a multidisciplinary strategy for management of mediastinal parathyroid adenoma as a cause of persistent primary hyperparathyroidism. Ann Surg (1992) 1.57
Transcription of the genomes of type 1 and type 3 reoviruses. J Virol (1968) 1.56
Inhibition of the release of acetylcholine from isolated guinea-pig ileum by crystalline tetrodotoxin. J Pharmacol Exp Ther (1966) 1.55
Contrasting effect of alpha/beta- and gamma-interferons on expression of macrophage Ia antigens. J Exp Med (1986) 1.55
CS-514, a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase: tissue-selective inhibition of sterol synthesis and hypolipidemic effect on various animal species. Biochim Biophys Acta (1986) 1.55
Hypermethylation in the retinoblastoma gene is associated with unilateral, sporadic retinoblastoma. Cancer Genet Cytogenet (1997) 1.55
Isolation and characterization of the bovine corticotropin/beta-lipotropin precursor gene. Eur J Biochem (1981) 1.54
The protein-coding sequence of the bovine ACTH-beta-LPH precursor gene is split near the signal peptide region. Nature (1980) 1.54