Published in J Biol Chem on April 01, 1994
Signal transduction cascades regulating fungal development and virulence. Microbiol Mol Biol Rev (2000) 5.49
Cyclic AMP-dependent protein kinase regulates pseudohyphal differentiation in Saccharomyces cerevisiae. Mol Cell Biol (1999) 3.22
Schizosaccharomyces pombe atf1+ encodes a transcription factor required for sexual development and entry into stationary phase. EMBO J (1995) 2.67
The cAMP-dependent protein kinase catalytic subunit is required for appressorium formation and pathogenesis by the rice blast pathogen Magnaporthe grisea. Plant Cell (1995) 2.46
Regulators of pseudohyphal differentiation in Saccharomyces cerevisiae identified through multicopy suppressor analysis in ammonium permease mutant strains. Genetics (1998) 2.21
The Schizosaccharomyces pombe mei4+ gene encodes a meiosis-specific transcription factor containing a forkhead DNA-binding domain. Mol Cell Biol (1998) 1.97
Schizosaccharomyces pombe pcr1+ encodes a CREB/ATF protein involved in regulation of gene expression for sexual development. Mol Cell Biol (1996) 1.82
Identification of a cAMP-dependent protein kinase catalytic subunit required for virulence and morphogenesis in Ustilago maydis. Proc Natl Acad Sci U S A (1998) 1.77
Glucose monitoring in fission yeast via the Gpa2 galpha, the git5 Gbeta and the git3 putative glucose receptor. Genetics (2000) 1.56
sck1, a high copy number suppressor of defects in the cAMP-dependent protein kinase pathway in fission yeast, encodes a protein homologous to the Saccharomyces cerevisiae SCH9 kinase. Genetics (1995) 1.37
Protein kinase A regulates sexual development and gluconeogenesis through phosphorylation of the Zn finger transcriptional activator Rst2p in fission yeast. Mol Cell Biol (2002) 1.35
The sak1+ gene of Schizosaccharomyces pombe encodes an RFX family DNA-binding protein that positively regulates cyclic AMP-dependent protein kinase-mediated exit from the mitotic cell cycle. Mol Cell Biol (1995) 1.27
Rapamycin specifically interferes with the developmental response of fission yeast to starvation. J Bacteriol (1997) 1.25
Glucose sensing via the protein kinase A pathway in Schizosaccharomyces pombe. Biochem Soc Trans (2005) 1.25
Protein kinase A and mitogen-activated protein kinase pathways antagonistically regulate fission yeast fbp1 transcription by employing different modes of action at two upstream activation sites. Mol Cell Biol (2000) 1.24
The fission yeast git5 gene encodes a Gbeta subunit required for glucose-triggered adenylate cyclase activation. Genetics (2000) 1.24
The S. pombe SAGA complex controls the switch from proliferation to sexual differentiation through the opposing roles of its subunits Gcn5 and Spt8. Genes Dev (2008) 1.24
A zinc-finger protein, Rst2p, regulates transcription of the fission yeast ste11(+) gene, which encodes a pivotal transcription factor for sexual development. Mol Biol Cell (2000) 1.19
Transcriptional regulators of the Schizosaccharomyces pombe fbp1 gene include two redundant Tup1p-like corepressors and the CCAAT binding factor activation complex. Genetics (2001) 1.16
Cholera toxin induces malignant glioma cell differentiation via the PKA/CREB pathway. Proc Natl Acad Sci U S A (2007) 1.11
Regulation of entry into gametogenesis. Philos Trans R Soc Lond B Biol Sci (2011) 1.10
Schizosaccharomyces pombe Git7p, a member of the Saccharomyces cerevisiae Sgtlp family, is required for glucose and cyclic AMP signaling, cell wall integrity, and septation. Eukaryot Cell (2002) 1.10
The pkaB gene encoding the secondary protein kinase A catalytic subunit has a synthetic lethal interaction with pkaA and plays overlapping and opposite roles in Aspergillus nidulans. Eukaryot Cell (2005) 1.09
Suppressors of an adenylate cyclase deletion in the fission yeast Schizosaccharomyces pombe. Eukaryot Cell (2004) 1.08
The Schizosaccharomyces pombe pyp1 protein tyrosine phosphatase negatively regulates nutrient monitoring pathways. J Cell Sci (1996) 1.08
Novel factor highly conserved among eukaryotes controls sexual development in fission yeast. Mol Cell Biol (1998) 1.07
Cloning of cDNAs from Arabidopsis thaliana that encode putative protein phosphatase 2C and a human Dr1-like protein by transformation of a fission yeast mutant. Nucleic Acids Res (1994) 1.07
Pmt1, a Dnmt2 homolog in Schizosaccharomyces pombe, mediates tRNA methylation in response to nutrient signaling. Nucleic Acids Res (2012) 1.07
Atf1-Pcr1-M26 complex links stress-activated MAPK and cAMP-dependent protein kinase pathways via chromatin remodeling of cgs2+. J Biol Chem (2004) 1.05
Control of metaphase-anaphase progression by proteolysis: cyclosome function regulated by the protein kinase A pathway, ubiquitination and localization. Philos Trans R Soc Lond B Biol Sci (1999) 1.02
Gef1p and Scd1p, the Two GDP-GTP exchange factors for Cdc42p, form a ring structure that shrinks during cytokinesis in Schizosaccharomyces pombe. Mol Biol Cell (2003) 1.01
An RNA binding protein negatively controlling differentiation in fission yeast. Mol Cell Biol (1998) 0.98
In vivo activation of protein kinase A in Schizosaccharomyces pombe requires threonine phosphorylation at its activation loop and is dependent on PDK1. Genetics (2004) 0.95
The phospholipase B homolog Plb1 is a mediator of osmotic stress response and of nutrient-dependent repression of sexual differentiation in the fission yeast Schizosaccharomyces pombe. Mol Genet Genomics (2003) 0.92
A starvation-specific serine protease gene, isp6+, is involved in both autophagy and sexual development in Schizosaccharomyces pombe. Curr Genet (2006) 0.88
Slm9, a novel nuclear protein involved in mitotic control in fission yeast. Genetics (2000) 0.87
zds1, a novel gene encoding an ortholog of Zds1 and Zds2, controls sexual differentiation, cell wall integrity and cell morphology in fission yeast. Genetics (2005) 0.86
Regulation of mRNA export by nutritional status in fission yeast. Genetics (1999) 0.85
TOR and PKA pathways synergize at the level of the Ste11 transcription factor to prevent mating and meiosis in fission yeast. PLoS One (2010) 0.83
Ran1 functions to control the Cdc10/Sct1 complex through Puc1. Mol Biol Cell (1997) 0.83
A novel gene, msa1, inhibits sexual differentiation in Schizosaccharomyces pombe. Genetics (2004) 0.83
Regulation of the subcellular localization of cyclic AMP-dependent protein kinase in response to physiological stresses and sexual differentiation in the fission yeast Schizosaccharomyces pombe. Eukaryot Cell (2008) 0.83
Fission yeast Ryh1 GTPase activates TOR Complex 2 in response to glucose. Cell Cycle (2015) 0.83
Moc3, a novel Zn finger type protein involved in sexual development, ascus formation, and stress response of Schizosaccharomyces pombe. Curr Genet (2005) 0.82
Regulation and role of an RNA-binding protein Msa2 in controlling the sexual differentiation of fission yeast. Curr Genet (2011) 0.81
Characterization of mutants devoid of neutral trehalase activity in the fission yeast Schizosaccharomyces pombe: partial protection from heat shock and high-salt stress. J Bacteriol (1998) 0.81
The MAP kinase Pmk1 and protein kinase A are required for rotenone resistance in the fission yeast, Schizosaccharomyces pombe. Biochem Biophys Res Commun (2010) 0.80
Phosphorylation of the protein kinase A catalytic subunit is induced by cyclic AMP deficiency and physiological stresses in the fission yeast, Schizosaccharomyces pombe. Biochem Biophys Res Commun (2010) 0.79
Fission Yeast CSL Transcription Factors: Mapping Their Target Genes and Biological Roles. PLoS One (2015) 0.79
Sla1, a Schizosaccharomyces pombe homolog of the human La protein, induces ectopic meiosis when its C terminus is truncated. Eukaryot Cell (2003) 0.79
Expression pattern and phenotypic characterization of the mutant strain reveals target genes and processes regulated by pka1 in the dimorphic fission yeast Schizosaccharomyces japonicus. Curr Genet (2016) 0.79
Inactivation of Ran1/Pat1 kinase bypasses the requirement for high-level expression of mei2 during fission yeast meiosis. Curr Genet (2003) 0.78
Multistep regulation of protein kinase A in its localization, phosphorylation and binding with a regulatory subunit in fission yeast. Curr Genet (2011) 0.78
PKA antagonizes CLASP-dependent microtubule stabilization to re-localize Pom1 and buffer cell size upon glucose limitation. Nat Commun (2015) 0.75
Bacillus bombysepticus α-Toxin Binding to G Protein-Coupled Receptor Kinase 2 Regulates cAMP/PKA Signaling Pathway to Induce Host Death. PLoS Pathog (2016) 0.75
Possible involvement of nitric oxide and reactive oxygen species in glucose deprivation-induced activation of transcription factor rst2. PLoS One (2013) 0.75
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature (2002) 28.79
Crystal structure of rhodopsin: A G protein-coupled receptor. Science (2000) 28.60
An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements. Biochem Biophys Res Commun (1997) 14.09
Essential Bacillus subtilis genes. Proc Natl Acad Sci U S A (2003) 14.01
Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain. Genes Dev (1999) 13.43
Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin. Nature (1986) 9.63
Confined lateral diffusion of membrane receptors as studied by single particle tracking (nanovid microscopy). Effects of calcium-induced differentiation in cultured epithelial cells. Biophys J (1993) 9.35
In vitro and in vivo antibacterial activity of T-1220, a new semisynthetic penicillin. Antimicrob Agents Chemother (1977) 7.35
Congenital bile duct cysts: Classification, operative procedures, and review of thirty-seven cases including cancer arising from choledochal cyst. Am J Surg (1977) 7.08
Hepatitis C virus infection is associated with the development of hepatocellular carcinoma. Proc Natl Acad Sci U S A (1990) 6.96
Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice. Proc Natl Acad Sci U S A (2001) 6.78
Structural basis of glutamate recognition by a dimeric metabotropic glutamate receptor. Nature (2000) 6.58
Large-scale analysis of gene function in Caenorhabditis elegans by high-throughput RNAi. Curr Biol (2001) 6.05
Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages. J Biol Chem (2000) 5.75
Regulation of transcription by dimerization of erythroid factor NF-E2 p45 with small Maf proteins. Nature (1994) 4.20
High sensitivity of Nrf2 knockout mice to acetaminophen hepatotoxicity associated with decreased expression of ARE-regulated drug metabolizing enzymes and antioxidant genes. Toxicol Sci (2001) 4.02
Structure of the bacterial flagellar protofilament and implications for a switch for supercoiling. Nature (2001) 3.92
Regulation of transcription of the Reovirus genome. J Mol Biol (1968) 3.85
Proposal for a new clinical entity, IgG4-positive multiorgan lymphoproliferative syndrome: analysis of 64 cases of IgG4-related disorders. Ann Rheum Dis (2008) 3.77
Phosphatidylinositol 4,5-bisphosphate induces actin-based movement of raft-enriched vesicles through WASP-Arp2/3. Curr Biol (2000) 3.75
Bach proteins belong to a novel family of BTB-basic leucine zipper transcription factors that interact with MafK and regulate transcription through the NF-E2 site. Mol Cell Biol (1996) 3.72
Immunoadjuvant activities of synthetic N-acetyl-muramyl-peptides or -amino acids. Biken J (1975) 3.69
Structure and expression of human B cell stimulatory factor-2 (BSF-2/IL-6) gene. EMBO J (1987) 3.64
Interleukin-6 deficient mice are protected from bone loss caused by estrogen depletion. EMBO J (1994) 3.60
Role of a ras homolog in the life cycle of Schizosaccharomyces pombe. Cell (1986) 3.54
A yeast mitogen-activated protein kinase homolog (Mpk1p) mediates signalling by protein kinase C. Mol Cell Biol (1993) 3.47
Schizosaccharomyces pombe ste11+ encodes a transcription factor with an HMG motif that is a critical regulator of sexual development. Genes Dev (1991) 3.26
Genetic organization of the bacterial conjugative transposon Tn916. J Bacteriol (1988) 3.18
In vitro and in vivo activities of anti-influenza virus compound T-705. Antimicrob Agents Chemother (2002) 3.17
Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus. Structure (1999) 3.04
Protein kinase C phosphorylates the inhibitory guanine-nucleotide-binding regulatory component and apparently suppresses its function in hormonal inhibition of adenylate cyclase. Eur J Biochem (1985) 3.04
Fission yeast Taz1 protein is required for meiotic telomere clustering and recombination. Nature (1998) 2.95
Nrf2-deficient female mice develop lupus-like autoimmune nephritis. Kidney Int (2001) 2.90
In vitro and in vivo antimicrobial activities of T-3811ME, a novel des-F(6)-quinolone. Antimicrob Agents Chemother (1999) 2.88
Murine and human T-lymphocyte GATA-3 factors mediate transcription through a cis-regulatory element within the human T-cell receptor delta gene enhancer. Mol Cell Biol (1991) 2.88
Mucosal adjuvant effect of cholera toxin in mice results from induction of T helper 2 (Th2) cells and IL-4. J Immunol (1995) 2.87
Cloning and characterization of a novel erythroid cell-derived CNC family transcription factor heterodimerizing with the small Maf family proteins. Mol Cell Biol (1995) 2.84
Selective inhibition of reovirus ribonucleic acid synthesis by cycloheximide. J Virol (1967) 2.84
Function of the 30 kd protein of tobacco mosaic virus: involvement in cell-to-cell movement and dispensability for replication. EMBO J (1987) 2.78
Nucleotide sequence of core and envelope genes of the hepatitis C virus genome derived directly from human healthy carriers. Nucleic Acids Res (1990) 2.76
The S.pombe mei2 gene encoding a crucial molecule for commitment to meiosis is under the regulation of cAMP. EMBO J (1988) 2.74
Qualitative comparison of carbon dioxide-induced change in cerebral near-infrared spectroscopy versus jugular venous oxygen saturation in adults with acute brain disease. Crit Care Med (1995) 2.74
Improvement of survival in patients with diffuse panbronchiolitis treated with low-dose erythromycin. Am J Respir Crit Care Med (1998) 2.69
Negative control for the initiation of meiosis in Schizosaccharomyces pombe. Proc Natl Acad Sci U S A (1985) 2.69
Defective virions of reovirus. J Virol (1970) 2.68
Coronary aneurysms in infants and young children with acute febrile mucocutaneous lymph node syndrome. J Pediatr (1975) 2.66
Spatial regulation of axonal glycoprotein expression on subsets of embryonic spinal neurons. Neuron (1988) 2.66
Gelsolin, a multifunctional actin regulatory protein. J Biol Chem (1999) 2.64
Structure and expression of a cloned cDNA for mouse interferon-beta. J Biol Chem (1983) 2.61
S. pombe mei2+ encodes an RNA-binding protein essential for premeiotic DNA synthesis and meiosis I, which cooperates with a novel RNA species meiRNA. Cell (1994) 2.57
Heat-inactivated proteins are rescued by the DnaK.J-GrpE set and ClpB chaperones. Proc Natl Acad Sci U S A (1999) 2.54
Structural units of reovirus ribonucleic acid and their possible functional significance. J Virol (1967) 2.54
Association between a large plasmid and 15- to 17-kilodalton antigens in virulent Rhodococcus equi. Infect Immun (1991) 2.52
Mutations in exons 2 and 3 of the cationic trypsinogen gene in Japanese families with hereditary pancreatitis. Gut (1999) 2.51
Mapping of a cluster of genes for components of the transcriptional and translational machineries of Escherichia coli. J Mol Biol (1977) 2.50
Clinicopathological study of fatal myocardial sarcoidosis. Ann N Y Acad Sci (1976) 2.47
Interleukin-6 (IL-6) functions as an in vitro autocrine growth factor in renal cell carcinomas. FEBS Lett (1989) 2.43
Type II myosin heavy chain encoded by the myo2 gene composes the contractile ring during cytokinesis in Schizosaccharomyces pombe. J Cell Biol (1997) 2.43
Hepatic uptake of chylomicron remnants in WHHL rabbits: a mechanism genetically distinct from the low density lipoprotein receptor. Proc Natl Acad Sci U S A (1982) 2.43
Serum undercarboxylated osteocalcin was inversely associated with plasma glucose level and fat mass in type 2 diabetes mellitus. Osteoporos Int (2010) 2.40
Accelerated DNA adduct formation in the lung of the Nrf2 knockout mouse exposed to diesel exhaust. Toxicol Appl Pharmacol (2001) 2.40
The Nrf2 transcription factor contributes both to the basal expression of glutathione S-transferases in mouse liver and to their induction by the chemopreventive synthetic antioxidants, butylated hydroxyanisole and ethoxyquin. Biochem Soc Trans (2000) 2.40
Prevention of lung reperfusion injury in rabbits by a monoclonal antibody against interleukin-8. Nature (1993) 2.38
Characterization of a fission yeast gene, gpa2, that encodes a G alpha subunit involved in the monitoring of nutrition. Genes Dev (1992) 2.36
Evaluation and characterization of catabolite-responsive elements (cre) of Bacillus subtilis. Nucleic Acids Res (2000) 2.35
Sarcoplasmic reticulum Ca2+ release is not a dominating factor in sinoatrial node pacemaker activity. Circ Res (2003) 2.32
Heme mediates derepression of Maf recognition element through direct binding to transcription repressor Bach1. EMBO J (2001) 2.32
Increased responsiveness of left ventricular apical myocardium to adrenergic stimuli. Cardiovasc Res (1993) 2.31
Contranscription of genes for RNA polymerase subunits beta and beta' with genes for ribosomal proteins in Escherichia coli. Proc Natl Acad Sci U S A (1978) 2.30
The world according to Maf. Nucleic Acids Res (1997) 2.30
Regulation of mucosal and systemic antibody responses by T helper cell subsets, macrophages, and derived cytokines following oral immunization with live recombinant Salmonella. J Immunol (1996) 2.30
Combined transcriptome and proteome analysis as a powerful approach to study genes under glucose repression in Bacillus subtilis. Nucleic Acids Res (2001) 2.28
Erythroid transcription factor GATA-1 is abundantly transcribed in mouse testis. Nature (1993) 2.25
Ventricular fibrillation. A possible mechanism of sudden death in patients and Wolff-Parkinson-White syndrome. Circulation (1971) 2.23
Serial inbreeding of rabbits with hereditary hyperlipidemia (WHHL-rabbit). Atherosclerosis (1980) 2.18
Structural analyses of DNA recognition by the AML1/Runx-1 Runt domain and its allosteric control by CBFbeta. Cell (2001) 2.15
Activation of the Keap1/Nrf2 pathway for neuroprotection by electrophilic [correction of electrophillic] phase II inducers. Proc Natl Acad Sci U S A (2006) 2.15
An updatable holographic three-dimensional display. Nature (2008) 2.14
PETT VI: a positron emission tomograph utilizing cesium fluoride scintillation detectors. J Comput Assist Tomogr (1982) 2.14
Identification of Bach2 as a B-cell-specific partner for small maf proteins that negatively regulate the immunoglobulin heavy chain gene 3' enhancer. EMBO J (1998) 2.13
Homologous activators of ras in fission and budding yeast. Nature (1990) 2.11
Role of transcription factor Nrf2 in the induction of hepatic phase 2 and antioxidative enzymes in vivo by the cancer chemoprotective agent, 3H-1, 2-dimethiole-3-thione. Mol Med (2001) 2.10
Molecular cloning and functional characterization of a new Cap'n' collar family transcription factor Nrf3. J Biol Chem (1999) 2.09
Deficiency of low density lipoprotein receptors in liver and adrenal gland of the WHHL rabbit, an animal model of familial hypercholesterolemia. Proc Natl Acad Sci U S A (1981) 2.08
A nontoxic mutant of cholera toxin elicits Th2-type responses for enhanced mucosal immunity. Proc Natl Acad Sci U S A (1997) 2.07
Accuracy of assessment of cardiac vagal tone by heart rate variability in normal subjects. Am J Cardiol (1991) 2.07
Receptor-dependent and receptor-independent degradation of low density lipoprotein in normal rabbits and in receptor-deficient mutant rabbits. J Biol Chem (1982) 2.06
Activation of TBK1 and IKKvarepsilon kinases by vesicular stomatitis virus infection and the role of viral ribonucleoprotein in the development of interferon antiviral immunity. J Virol (2004) 2.06
Arrest in primitive erythroid cell development caused by promoter-specific disruption of the GATA-1 gene. J Biol Chem (1997) 2.05
Essential requirement of BMPs-2/4 for both osteoblast and osteoclast formation in murine bone marrow cultures from adult mice: antagonism by noggin. J Bone Miner Res (2000) 2.03
Regulation of lens fiber cell differentiation by transcription factor c-Maf. J Biol Chem (1999) 2.00
Structural analysis of repetitive DNA sequences in the bovine corticotropin-beta-lipotropin precursor gene region. Nucleic Acids Res (1982) 1.99
Involvement of outer membrane protein TolC, a possible member of the mar-sox regulon, in maintenance and improvement of organic solvent tolerance of Escherichia coli K-12. J Bacteriol (1998) 1.98
Impaired receptor-mediated catabolism of low density lipoprotein in the WHHL rabbit, an animal model of familial hypercholesterolemia. Proc Natl Acad Sci U S A (1982) 1.98
Temporary inhalation anaesthesia in experimental pigs. Lab Anim (2009) 1.98