Molecular characterization of phagosomes.

Virulent and avirulent strains of Francisella tularensis prevent acidification and maturation of their phagosomes and escape into the cytoplasm in human macrophages. Infect Immun (2004) 4.31

The phagosome proteome: insight into phagosome functions. J Cell Biol (2001) 4.23

Rab 7: an important regulator of late endocytic membrane traffic. J Cell Biol (1995) 4.23

Brucella abortus transits through the autophagic pathway and replicates in the endoplasmic reticulum of nonprofessional phagocytes. Infect Immun (1998) 3.92

Phagosome maturation: aging gracefully. Biochem J (2002) 3.42

Natural resistance to infection with intracellular pathogens: the Nramp1 protein is recruited to the membrane of the phagosome. J Exp Med (1997) 2.34

Molecular requirements for bi-directional movement of phagosomes along microtubules. J Cell Biol (1997) 2.13

Early phagosomes in dendritic cells form a cellular compartment sufficient for cross presentation of exogenous antigens. Proc Natl Acad Sci U S A (2003) 2.09

Modulation of Rab5 and Rab7 recruitment to phagosomes by phosphatidylinositol 3-kinase. Mol Cell Biol (2003) 2.03

Involvement of ezrin/moesin in de novo actin assembly on phagosomal membranes. EMBO J (2000) 1.85

Ezrin/radixin/moesin proteins and Rho GTPase signalling in leucocytes. Immunology (2004) 1.82

Manipulation of rab GTPase function by intracellular bacterial pathogens. Microbiol Mol Biol Rev (2007) 1.82

Coxiella burnetii localizes in a Rab7-labeled compartment with autophagic characteristics. Infect Immun (2002) 1.79

Caspase-11 promotes the fusion of phagosomes harboring pathogenic bacteria with lysosomes by modulating actin polymerization. Immunity (2012) 1.77

Inhibition of phagolysosomal biogenesis by the Leishmania lipophosphoglycan. J Exp Med (1997) 1.54

Force measurements on cargoes in living cells reveal collective dynamics of microtubule motors. Proc Natl Acad Sci U S A (2012) 1.47

G protein beta subunit-null mutants are impaired in phagocytosis and chemotaxis due to inappropriate regulation of the actin cytoskeleton. J Cell Biol (1998) 1.46

Hemophagocytic macrophages harbor Salmonella enterica during persistent infection. PLoS Pathog (2007) 1.41

Contribution of phosphatidylserine to membrane surface charge and protein targeting during phagosome maturation. J Cell Biol (2009) 1.38

ATP-dependent membrane assembly of F-actin facilitates membrane fusion. Mol Biol Cell (2001) 1.37

Membrane proteomics of phagosomes suggests a connection to autophagy. Proc Natl Acad Sci U S A (2008) 1.34

Different fates of phagocytosed particles after delivery into macrophage lysosomes. J Cell Biol (1996) 1.31

Mechanism of inducible nitric oxide synthase exclusion from mycobacterial phagosomes. PLoS Pathog (2007) 1.28

Phosphoinositides regulate membrane-dependent actin assembly by latex bead phagosomes. Mol Biol Cell (2002) 1.25

Dynein-mediated vesicle transport controls intracellular Salmonella replication. Mol Biol Cell (2004) 1.24

Acquisition of Hrs, an essential component of phagosomal maturation, is impaired by mycobacteria. Mol Cell Biol (2004) 1.20

The human fungal pathogen Cryptococcus neoformans escapes macrophages by a phagosome emptying mechanism that is inhibited by Arp2/3 complex-mediated actin polymerisation. PLoS Pathog (2010) 1.20

High-resolution dissection of phagosome maturation reveals distinct membrane trafficking phases. Mol Biol Cell (2002) 1.18

Myosin Va bound to phagosomes binds to F-actin and delays microtubule-dependent motility. Mol Biol Cell (2001) 1.13

Pathogen destruction versus intracellular survival: the role of lipids as phagosomal fate determinants. J Clin Invest (2008) 1.10

Molecular characterization of the evolution of phagosomes. Mol Syst Biol (2010) 1.08

Evidence for a recycling role for Rab7 in regulating a late step in endocytosis and in retention of lysosomal enzymes in Dictyostelium discoideum. Mol Biol Cell (1997) 1.08

Sequential actions of Rab5 and Rab7 regulate endocytosis in the Xenopus oocyte. J Cell Biol (1997) 1.08

Activation of the pyrin inflammasome by intracellular Burkholderia cenocepacia. J Immunol (2012) 1.07

Annexin A6-induced alterations in cholesterol transport and caveolin export from the Golgi complex. Traffic (2007) 1.05

Involvement of syntaxin 18, an endoplasmic reticulum (ER)-localized SNARE protein, in ER-mediated phagocytosis. Mol Biol Cell (2006) 1.04

Analysis of PRA1 and its relationship to Candida albicans- macrophage interactions. Infect Immun (2008) 1.01

Staphylococcus aureus escapes more efficiently from the phagosome of a cystic fibrosis bronchial epithelial cell line than from its normal counterpart. Infect Immun (2006) 1.00

Pathogenic mycobacteria disrupt the macrophage actin filament network. Infect Immun (2000) 1.00

Live Salmonella recruits N-ethylmaleimide-sensitive fusion protein on phagosomal membrane and promotes fusion with early endosome. J Cell Biol (2000) 0.99

The association of annexin I with early endosomes is regulated by Ca2+ and requires an intact N-terminal domain. Mol Biol Cell (1996) 0.97

Contributions of proteomics to understanding phagosome maturation. Cell Microbiol (2008) 0.97

From Q Fever to Coxiella burnetii Infection: a Paradigm Change. Clin Microbiol Rev (2017) 0.93

Quantitative proteomics reveals that only a subset of the endoplasmic reticulum contributes to the phagosome. Mol Cell Proteomics (2012) 0.91

Phagosome acidification has opposite effects on intracellular survival of Bordetella pertussis and B. bronchiseptica. Infect Immun (2000) 0.89

The role of CD38 in Fcγ receptor (FcγR)-mediated phagocytosis in murine macrophages. J Biol Chem (2012) 0.89

Organelle membrane proteomics reveals differential influence of mycobacterial lipoglycans on macrophage phagosome maturation and autophagosome accumulation. J Proteome Res (2010) 0.88

SNAP-23 regulates phagosome formation and maturation in macrophages. Mol Biol Cell (2012) 0.86

A simpler way of comparing the labelling densities of cellular compartments illustrated using data from VPARP and LAMP-1 immunogold labelling experiments. Histochem Cell Biol (2003) 0.86

Phylogeny and evolution of Rab7 and Rab9 proteins. BMC Evol Biol (2009) 0.85

Analysis of phagosomal proteomes: from latex-bead to bacterial phagosomes. Proteomics (2010) 0.84

Label-free proteomics and systems biology analysis of mycobacterial phagosomes in dendritic cells and macrophages. J Proteome Res (2011) 0.83

Purification of intracellular compartments involved in antigen processing: a new method based on magnetic sorting. Biochem J (1999) 0.83

An in vitro-differentiated human cell line as a model system to study the interaction of Neisseria gonorrhoeae with phagocytic cells. Infect Immun (1997) 0.83

Phototactic migration of Dictyostelium cells is linked to a new type of gelsolin-related protein. Mol Biol Cell (1999) 0.83

Recruitment of coat-protein-complex proteins on to phagosomal membranes is regulated by a brefeldin A-sensitive ADP-ribosylation factor. Biochem J (2001) 0.83

Crotalus durissus terrificus venom interferes with morphological, functional, and biochemical changes in murine macrophage. Mediators Inflamm (2005) 0.81

Helicobacter pylori phagosome maturation in primary human macrophages. Gut Pathog (2011) 0.80

The pathway of cross-presentation is influenced by the particle size of phagocytosed antigen. Immunology (2012) 0.79

Proteomic characterization of phagosomal membrane microdomains during phagolysosome biogenesis and evolution. Mol Cell Proteomics (2012) 0.78

Infection by Mycoplasma hyorhinis strongly enhances uptake of antisense oligonucleotides: a reassessment of receptor-mediated endocytosis in the HepG2 cell line. Nucleic Acids Res (2003) 0.78

Purification and proteomics of pathogen-modified vacuoles and membranes. Front Cell Infect Microbiol (2015) 0.76

Dengue virus compartmentalization during antibody-enhanced infection. Sci Rep (2017) 0.75

The Monomeric GTPase Rab35 Regulates Phagocytic Cup Formation and Phagosomal Maturation in Entamoeba histolytica. J Biol Chem (2017) 0.75

Mass spectrometry imaging of biomarker lipids for phagocytosis and signalling during focal cerebral ischaemia. Sci Rep (2016) 0.75

The Voltage-Dependent Anion Channels (VDAC) of Mycobacterium avium phagosome are associated with bacterial survival and lipid export in macrophages. Sci Rep (2017) 0.75

The trans Golgi network: sorting at the exit site of the Golgi complex. Science (1986) 10.08

Lipid sorting in epithelial cells. Biochemistry (1988) 7.64

On the preparation of cryosections for immunocytochemistry. J Ultrastruct Res (1984) 5.12

Beta-COP, a 110 kd protein associated with non-clathrin-coated vesicles and the Golgi complex, shows homology to beta-adaptin. Cell (1991) 5.10

Exit of newly synthesized membrane proteins from the trans cisterna of the Golgi complex to the plasma membrane. J Cell Biol (1985) 4.93

A monoclonal antibody against a 135-K Golgi membrane protein. EMBO J (1982) 4.89

Characterization of the early endosome and putative endocytic carrier vesicles in vivo and with an assay of vesicle fusion in vitro. J Cell Biol (1989) 4.88

Assembly of vaccinia virus: the second wrapping cisterna is derived from the trans Golgi network. J Virol (1994) 4.67

Passage of viral membrane proteins through the Golgi complex. J Mol Biol (1981) 4.48

Assembly of vaccinia virus: role of the intermediate compartment between the endoplasmic reticulum and the Golgi stacks. J Cell Biol (1993) 4.34

Biogenesis of phagolysosomes proceeds through a sequential series of interactions with the endocytic apparatus. J Cell Biol (1994) 4.26

Beta-COP is essential for biosynthetic membrane transport from the endoplasmic reticulum to the Golgi complex in vivo. Cell (1993) 4.24

A highly conserved eukaryotic protein family possessing properties of polypeptide chain release factor. Nature (1994) 4.21

Dissection of the Golgi complex. I. Monensin inhibits the transport of viral membrane proteins from medial to trans Golgi cisternae in baby hamster kidney cells infected with Semliki Forest virus. J Cell Biol (1983) 4.20

Actin-based motility of vaccinia virus. Nature (1995) 4.12

Cytoplasmic dynein-dependent vesicular transport from early to late endosomes. J Cell Biol (1993) 4.12

Compilation of mutant suppressor tRNA sequences. Nucleic Acids Res (1982) 3.73

Cell cycle-dependent variations in the distribution of the nuclear protein cyclin proliferating cell nuclear antigen in cultured cells: subdivision of S phase. Proc Natl Acad Sci U S A (1985) 3.62

A search for differential polypeptide synthesis throughout the cell cycle of HeLa cells. J Cell Biol (1980) 3.50

Polarity of actin at the leading edge of cultured cells. Nature (1978) 3.40

Arrest of mycobacterial phagosome maturation is caused by a block in vesicle fusion between stages controlled by rab5 and rab7. J Biol Chem (1997) 3.32

How proteins move lipids and lipids move proteins. Nat Rev Mol Cell Biol (2001) 3.26

The function of tight junctions in maintaining differences in lipid composition between the apical and the basolateral cell surface domains of MDCK cells. EMBO J (1986) 3.20

Viral membrane proteins acquire galactose in trans Golgi cisternae during intracellular transport. J Cell Biol (1982) 3.18

The analgesic effect of sucrose in full term infants: a randomised controlled trial. BMJ (1995) 3.09

Kinetics of intracellular transport and sorting of lysosomal membrane and plasma membrane proteins. J Cell Biol (1987) 3.02

Mutations in the cytoplasmic domain of the 275 kd mannose 6-phosphate receptor differentially alter lysosomal enzyme sorting and endocytosis. Cell (1989) 2.97

Filament arrangements in negatively stained cultured cells: the organization of actin. Cytobiologie (1978) 2.93

Characterization of the budding compartment of mouse hepatitis virus: evidence that transport from the RER to the Golgi complex requires only one vesicular transport step. J Cell Biol (1994) 2.92

Immunoelectron microscopy using thin, frozen sections: application to studies of the intracellular transport of Semliki Forest virus spike glycoproteins. Methods Enzymol (1983) 2.89

MDR1 P-glycoprotein is a lipid translocase of broad specificity, while MDR3 P-glycoprotein specifically translocates phosphatidylcholine. Cell (1996) 2.87

Density of newly synthesized plasma membrane proteins in intracellular membranes II. Biochemical studies. J Cell Biol (1984) 2.81

Three-dimensional structure of endosomes in BHK-21 cells. Proc Natl Acad Sci U S A (1986) 2.81

Rapid deubiquitination of nucleosomal histones in human tumor cells caused by proteasome inhibitors and stress response inducers: effects on replication, transcription, translation, and the cellular stress response. Biochemistry (1997) 2.73

Immunocytochemical characterization of the endocytic and phagolysosomal compartments in peritoneal macrophages. J Cell Biol (1992) 2.71

Reclustering of scattered Golgi elements occurs along microtubules. Eur J Cell Biol (1989) 2.68

Rab GDP dissociation inhibitor as a general regulator for the membrane association of rab proteins. J Biol Chem (1993) 2.62

Analysis of CD44-containing lipid rafts: Recruitment of annexin II and stabilization by the actin cytoskeleton. J Cell Biol (1999) 2.60

Meeting of the apical and basolateral endocytic pathways of the Madin-Darby canine kidney cell in late endosomes. J Cell Biol (1989) 2.51

Hierarchy of mechanisms involved in generating Na/K-ATPase polarity in MDCK epithelial cells. J Cell Biol (1995) 2.45

Characterisation of two major cellular poly(rC)-binding human proteins, each containing three K-homologous (KH) domains. Eur J Biochem (1995) 2.44

Continuous, hyperfractionated, accelerated radiotherapy (CHART) versus conventional radiotherapy in non-small cell lung cancer: mature data from the randomised multicentre trial. CHART Steering committee. Radiother Oncol (1999) 2.43

A novel 14-kilodalton protein interacts with the mitogen-activated protein kinase scaffold mp1 on a late endosomal/lysosomal compartment. J Cell Biol (2001) 2.42

Reference points for comparisons of two-dimensional maps of proteins from different human cell types defined in a pH scale where isoelectric points correlate with polypeptide compositions. Electrophoresis (1994) 2.41

Cloning and expression of human lecithin-cholesterol acyltransferase cDNA. Proc Natl Acad Sci U S A (1986) 2.27

Rab11, a small GTPase associated with both constitutive and regulated secretory pathways in PC12 cells. FEBS Lett (1993) 2.25

Purification and characterization of oil-bodies (oleosomes) and oil-body boundary proteins (oleosins) from the developing cotyledons of sunflower (Helianthus annuus L.) Biochem J (1996) 2.23

Protein import into yeast mitochondria is accelerated by the outer membrane protein MAS70. EMBO J (1990) 2.22

Density of newly synthesized plasma membrane proteins in intracellular membranes. I. Stereological studies. J Cell Biol (1984) 2.20

Dissection of the Golgi complex. II. Density separation of specific Golgi functions in virally infected cells treated with monensin. J Cell Biol (1983) 2.20

Viruses budding from either the apical or the basolateral plasma membrane domain of MDCK cells have unique phospholipid compositions. EMBO J (1982) 2.19

MOM19, an import receptor for mitochondrial precursor proteins. Cell (1989) 2.18

Assembly of vaccinia virus: effects of rifampin on the intracellular distribution of viral protein p65. J Virol (1994) 2.17

Entry of the two infectious forms of vaccinia virus at the plasma membane is signaling-dependent for the IMV but not the EEV. Mol Biol Cell (2000) 2.16

Monoclonal antibodies to a nuclear protein (PCNA/cyclin) associated with DNA replication. Exp Cell Res (1987) 2.13

Molecular requirements for bi-directional movement of phagosomes along microtubules. J Cell Biol (1997) 2.13

Architecture and polypeptide composition of HeLa cytoskeletons. Modification of cytoarchitectural polypeptides during mitosis. J Mol Biol (1982) 2.13

The recycling endosome of Madin-Darby canine kidney cells is a mildly acidic compartment rich in raft components. Mol Biol Cell (2000) 2.11

Identification of the major membrane and core proteins of vaccinia virus by two-dimensional electrophoresis. J Virol (1996) 2.08

Nonsense suppressors of Saccharomyces cerevisiae can be generated by mutation of the tyrosine tRNA anticodon. Nature (1976) 2.07

Distribution of newly synthesized lysosomal enzymes in the endocytic pathway of normal rat kidney cells. J Cell Biol (1991) 2.04

Identification of a nuclear and of a cytoplasmic polypeptide whose relative proportions are sensitive to changes in the rate of cell proliferation. Exp Cell Res (1981) 1.99

Annexin II is a major component of fusogenic endosomal vesicles. J Cell Biol (1993) 1.99

The acylation of sn-glycerol 3-phosphate and the metabolism of phosphatidate in microsomal preparations from the developing cotyledons of safflower (Carthamus tinctorius L.) seed. Biochem J (1985) 1.99

A mitochondrial import receptor for the ADP/ATP carrier. Cell (1990) 1.95

Newly synthesized G protein of vesicular stomatitis virus is not transported to the Golgi complex in mitotic cells. J Cell Biol (1985) 1.94

Quantitation in immunocytochemistry: correlation of immunogold labeling to absolute number of membrane antigens. J Histochem Cytochem (1986) 1.91

The tight junction does not allow lipid molecules to diffuse from one epithelial cell to the next. Nature (1986) 1.91

Estimation of the amount of internalized ricin that reaches the trans-Golgi network. J Cell Biol (1988) 1.90

Identification of a mitochondrial receptor complex required for recognition and membrane insertion of precursor proteins. Nature (1990) 1.90

A novel immunogold cryoelectron microscopic approach to investigate the structure of the intracellular and extracellular forms of vaccinia virus. EMBO J (1996) 1.88

Protein-electroblotting and -microsequencing strategies in generating protein data bases from two-dimensional gels. Proc Natl Acad Sci U S A (1989) 1.87

Specificity of CTL interactions with peptide-MHC class I tetrameric complexes is temperature dependent. J Immunol (1999) 1.86

The phospholipid composition of extracellular herpes simplex virions differs from that of host cell nuclei. Virology (1994) 1.86

Rab17, a novel small GTPase, is specific for epithelial cells and is induced during cell polarization. J Cell Biol (1993) 1.86

Involvement of ezrin/moesin in de novo actin assembly on phagosomal membranes. EMBO J (2000) 1.85

The role of a 21-kDa viral membrane protein in the assembly of vaccinia virus from the intermediate compartment. J Biol Chem (1996) 1.79

Cyclin: a nuclear protein whose level correlates directly with the proliferative state of normal as well as transformed cells. Leuk Res (1984) 1.79

Glucosylceramide is synthesized at the cytosolic surface of various Golgi subfractions. J Cell Biol (1992) 1.79

Identification, molecular cloning, expression and chromosome mapping of a family of transformation upregulated hnRNP-K proteins derived by alternative splicing. J Mol Biol (1994) 1.78

Differential endocytosis of CD4 in lymphocytic and nonlymphocytic cells. J Exp Med (1991) 1.78

The mammalian homolog of yeast Sec13p is enriched in the intermediate compartment and is essential for protein transport from the endoplasmic reticulum to the Golgi apparatus. Mol Cell Biol (1997) 1.77

VIP21/caveolin, glycosphingolipid clusters and the sorting of glycosylphosphatidylinositol-anchored proteins in epithelial cells. EMBO J (1994) 1.75

A T. cruzi-secreted protein immunologically related to the complement component C9: evidence for membrane pore-forming activity at low pH. Cell (1990) 1.73

Reversible phosphorylation--dephosphorylation determines the localization of rab4 during the cell cycle. EMBO J (1992) 1.72

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Up-dated catalogue of HeLa cell proteins: percentages and characteristics of the major cell polypeptides labeled with a mixture of 16 14C-labeled amino acids. Clin Chem (1982) 1.70

Intracellular transport and localization of major histocompatibility complex class II molecules and associated invariant chain. J Cell Biol (1991) 1.68

Lysosomal enzyme trafficking between phagosomes, endosomes, and lysosomes in J774 macrophages. Enrichment of cathepsin H in early endosomes. J Biol Chem (1998) 1.67

Direct visualization of the 10-nm (100-A)-filament network in whole and enucleated cultured cells. J Cell Sci (1978) 1.67

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Characterization of the coronavirus mouse hepatitis virus strain A59 small membrane protein E. J Virol (2000) 1.64

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Vaccinia virus membrane proteins p8 and p16 are cotranslationally inserted into the rough endoplasmic reticulum and retained in the intermediate compartment. J Virol (1997) 1.60