Published in Nucleic Acids Res on November 25, 1994
The human cytomegalovirus UL55 (gB) and UL75 (gH) glycoprotein ligands initiate the rapid activation of Sp1 and NF-kappaB during infection. J Virol (1997) 2.24
A compilation of cellular transcription factor interactions with the HIV-1 LTR promoter. Nucleic Acids Res (2000) 2.16
Complex transcriptional effects of p63 isoforms: identification of novel activation and repression domains. Mol Cell Biol (2002) 1.89
Induction of the transcription factor Sp1 during human cytomegalovirus infection mediates upregulation of the p65 and p105/p50 NF-kappaB promoters. J Virol (1997) 1.78
Transcription factor Sp3 is essential for post-natal survival and late tooth development. EMBO J (2000) 1.77
Physical interactions between Ets and NF-kappaB/NFAT proteins play an important role in their cooperative activation of the human immunodeficiency virus enhancer in T cells. J Virol (1997) 1.71
An inhibitor domain in Sp3 regulates its glutamine-rich activation domains. EMBO J (1996) 1.68
Sp3 encodes multiple proteins that differ in their capacity to stimulate or repress transcription. Nucleic Acids Res (1997) 1.61
Autostimulation of the Epstein-Barr virus BRLF1 promoter is mediated through consensus Sp1 and Sp3 binding sites. J Virol (2001) 1.47
Efficient transcription and replication of simian immunodeficiency virus in the absence of NF-kappaB and Sp1 binding elements. J Virol (1996) 1.39
Krüppel-associated box-mediated repression of RNA polymerase II promoters is influenced by the arrangement of basal promoter elements. Proc Natl Acad Sci U S A (1996) 1.23
Regulation of HIV-1 transcription in cells of the monocyte-macrophage lineage. Retrovirology (2009) 1.17
Sp3 is a transcriptional activator of the human alpha2(I) collagen gene. Nucleic Acids Res (1997) 1.13
TACC3 mediates the association of MBD2 with histone acetyltransferases and relieves transcriptional repression of methylated promoters. Nucleic Acids Res (2006) 1.12
MBDin, a novel MBD2-interacting protein, relieves MBD2 repression potential and reactivates transcription from methylated promoters. Mol Cell Biol (2003) 1.12
Stability of the Sp3-DNA complex is promoter-specific: Sp3 efficiently competes with Sp1 for binding to promoters containing multiple Sp-sites. Nucleic Acids Res (2003) 1.09
Transcriptional regulation of the human Sp1 gene promoter by the specificity protein (Sp) family members nuclear factor Y (NF-Y) and E2F. Biochem J (2003) 1.05
Transcription factor Sp3 antagonizes activation of the ornithine decarboxylase promoter by Sp1. Nucleic Acids Res (1997) 1.01
Naturally occurring human immunodeficiency virus type 1 long terminal repeats have a frequently observed duplication that binds RBF-2 and represses transcription. J Virol (1998) 0.97
Characterization of Sp1, AP-1, CBF and KRC binding sites and minisatellite DNA as functional elements of the metastasis-associated mts1/S100A4 gene intronic enhancer. Nucleic Acids Res (2001) 0.97
A fourth Sp1 site in the human immunodeficiency virus type 1 long terminal repeat is essential for negative-sense transcription. J Virol (1996) 0.95
Functional interactions between C/EBP, Sp1, and COUP-TF regulate human immunodeficiency virus type 1 gene transcription in human brain cells. J Virol (2000) 0.92
Inhibition of phosphodiesterase type IV suppresses human immunodeficiency virus type 1 replication and cytokine production in primary T cells: involvement of NF-kappaB and NFAT. J Virol (1998) 0.91
ras oncogene-dependent activation of the P4 promoter of minute virus of mice through a proximal P4 element interacting with the Ets family of transcription factors. J Virol (1996) 0.91
HIV-1 reactivation induced by the periodontal pathogens Fusobacterium nucleatum and Porphyromonas gingivalis involves Toll-like receptor 2 [corrected] and 9 activation in monocytes/macrophages. Clin Vaccine Immunol (2010) 0.90
Sp4-dependent repression of neurotrophin-3 limits dendritic branching. Mol Cell Neurosci (2009) 0.88
Sp3 is involved in the regulation of SOCS3 gene expression. Biochem J (2005) 0.88
Sp1 binding plays a critical role in Erb-B2- and v-ras-mediated downregulation of alpha2-integrin expression in human mammary epithelial cells. Mol Cell Biol (1996) 0.87
Differential transcriptional regulation of the human thrombin receptor gene by the Sp family of transcription factors in human endothelial cells. Biochem J (1998) 0.86
Mechanisms of HIV Transcriptional Regulation and Their Contribution to Latency. Mol Biol Int (2012) 0.86
Cellular transcription factors Sp1 and Sp3 suppress varicella-zoster virus origin-dependent DNA replication. J Virol (2008) 0.85
Transcriptional regulation of the KEL gene and Kell protein expression in erythroid and non-erythroid cells. Biochem J (2001) 0.84
HIV-1 transcriptional regulation in the central nervous system and implications for HIV cure research. J Neurovirol (2014) 0.84
Reduced basal transcriptional activity of central nervous system-derived HIV type 1 long terminal repeats. AIDS Res Hum Retroviruses (2012) 0.83
Chromatin, non-coding RNAs, and the expression of HIV. Viruses (2013) 0.83
Transcription factor Sp3 represses expression of p21CIP¹ via inhibition of productive elongation by RNA polymerase II. Mol Cell Biol (2013) 0.82
Down-regulation of human topoisomerase IIalpha expression correlates with relative amounts of specificity factors Sp1 and Sp3 bound at proximal and distal promoter regions. BMC Mol Biol (2007) 0.82
Different Sp1 family members differentially affect transcription from the human elongation factor 1 A-1 gene promoter. Biochem J (1998) 0.81
Unbiased proteomic analysis of proteins interacting with the HIV-1 5'LTR sequence: role of the transcription factor Meis. Nucleic Acids Res (2012) 0.80
A Cyclin T1 point mutation that abolishes positive transcription elongation factor (P-TEFb) binding to Hexim1 and HIV tat. Retrovirology (2014) 0.80
SP1-binding elements, within the common metaxin-thrombospondin 3 intergenic region, participate in the regulation of the metaxin gene. Nucleic Acids Res (1996) 0.79
Transcriptome analysis of spermatogenically regressed, recrudescent and active phase testis of seasonally breeding wall lizards Hemidactylus flaviviridis. PLoS One (2013) 0.79
In vivo transcriptional regulation of the human immunodeficiency virus in the central nervous system in transgenic mice. J Virol (1996) 0.79
Platelet-derived growth factor-stimulated expression of the MCP-1 immediate-early gene involves an inhibitory multiprotein complex. Mol Cell Biol (1999) 0.78
A negative regulatory element in the promoter region of the rat alpha 2A-adrenergic receptor gene overlaps an SP1 consensus binding site. Biochem J (1995) 0.78
Specificity proteins Sp1 and Sp3 interact with the rat GTP cyclohydrolase I proximal promoter to regulate transcription. J Neurochem (2007) 0.77
Mycobacterial and HIV infections up-regulated human zinc finger protein 134, a novel positive regulator of HIV-1 LTR activity and viral propagation. PLoS One (2014) 0.75
Differential regulation of the human nidogen gene promoter region by a novel cell-type-specific silencer element. Biochem J (1999) 0.75
Opinion: Inhibition of Blood-Brain Barrier Repair as a Mechanism in HIV-1 Disease. Front Neurosci (2017) 0.75
An inducible transcription factor activates expression of human immunodeficiency virus in T cells. Nature (1987) 19.23
Analysis of Sp1 in vivo reveals multiple transcriptional domains, including a novel glutamine-rich activation motif. Cell (1988) 12.68
Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domain. Cell (1987) 12.30
A vector for expressing GAL4(1-147) fusions in mammalian cells. Nucleic Acids Res (1989) 8.06
Activation of the AIDS retrovirus promoter by the cellular transcription factor, Sp1. Science (1986) 8.01
NF-kappa B and Rel: participants in a multiform transcriptional regulatory system. Int Rev Cytol (1993) 7.42
HTLV-1 transactivator induces interleukin-2 receptor expression through an NF-kappa B-like factor. Nature (1988) 7.35
The I kappa B proteins: multifunctional regulators of Rel/NF-kappa B transcription factors. Genes Dev (1993) 4.93
Different activation domains of Sp1 govern formation of multimers and mediate transcriptional synergism. Genes Dev (1991) 4.54
Synergistic activation by the glutamine-rich domains of human transcription factor Sp1. Cell (1989) 4.49
A cooperative interaction between NF-kappa B and Sp1 is required for HIV-1 enhancer activation. EMBO J (1993) 3.74
Sp1-mediated transcriptional activation is repressed by Sp3. EMBO J (1994) 3.27
Cloning of GT box-binding proteins: a novel Sp1 multigene family regulating T-cell receptor gene expression. Mol Cell Biol (1992) 3.10
The HIV-1 Tat protein activates transcription from an upstream DNA-binding site: implications for Tat function. Genes Dev (1991) 3.08
Functional roles for the TATA promoter and enhancers in basal and Tat-induced expression of the human immunodeficiency virus type 1 long terminal repeat. J Virol (1992) 2.93
Cloning by recognition site screening of two novel GT box binding proteins: a family of Sp1 related genes. Nucleic Acids Res (1992) 2.89
Does HIV-1 Tat induce a change in viral initiation rights? Cell (1993) 2.30
Sp1-dependent activation of a synthetic promoter by human immunodeficiency virus type 1 Tat protein. Proc Natl Acad Sci U S A (1991) 2.17
Role of SP1-binding domains in in vivo transcriptional regulation of the human immunodeficiency virus type 1 long terminal repeat. J Virol (1989) 2.14
Linker-scanning mutational analysis of the transcriptional activity of the human immunodeficiency virus type 1 long terminal repeat. J Virol (1991) 1.84
Regulation of HIV-1 gene expression. Annu Rev Immunol (1990) 1.66
Activation of HIV transcription by Tat. Curr Opin Genet Dev (1992) 1.57
Constitutive and IL-6-induced nuclear factors that interact with the human C-reactive protein promoter. EMBO J (1990) 1.53
Replication of type 1 human immunodeficiency viruses containing linker substitution mutations in the -201 to -130 region of the long terminal repeat. J Virol (1993) 1.37
Selective repression of transcriptional activators at a distance by the Drosophila Krüppel protein. Proc Natl Acad Sci U S A (1993) 1.30
Convergent transcription initiates from oppositely oriented promoters within the 5' end regions of Drosophila melanogaster F elements. Mol Cell Biol (1991) 1.15
Human immunodeficiency viruses containing heterologous enhancer/promoters are replication competent and exhibit different lymphocyte tropisms. J Virol (1993) 1.10
Increased spacing between Sp1 and TATAA renders human immunodeficiency virus type 1 replication defective: implication for Tat function. J Virol (1993) 1.06
Enhanced activity of human G6PD promoter transfected in HeLa cells producing high levels of HIV-1 Tat. Virology (1993) 0.96
Mutational analysis of the human endogenous ERV9 proviruses promoter region. Virology (1994) 0.89
Aux/IAA proteins repress expression of reporter genes containing natural and highly active synthetic auxin response elements. Plant Cell (1997) 11.61
ARF1, a transcription factor that binds to auxin response elements. Science (1997) 5.64
Transcription, organization, and sequence of an auxin-regulated gene cluster in soybean. Plant Cell (1989) 4.79
Activation and repression of transcription by auxin-response factors. Proc Natl Acad Sci U S A (1999) 4.21
Cloning and sequencing of the ribosomal RNA genes in maize: the 17S region. DNA (1984) 4.02
Dimerization and DNA binding of auxin response factors. Plant J (1999) 3.89
Rapid induction of selective transcription by auxins. Mol Cell Biol (1985) 3.77
A tale of three fingers: the family of mammalian Sp/XKLF transcription factors. Nucleic Acids Res (1999) 3.68
Soybean GH3 promoter contains multiple auxin-inducible elements. Plant Cell (1994) 3.68
AUX/IAA proteins are active repressors, and their stability and activity are modulated by auxin. Plant Cell (2001) 3.42
Sp1-mediated transcriptional activation is repressed by Sp3. EMBO J (1994) 3.27
Composite structure of auxin response elements. Plant Cell (1995) 2.94
Cloning by recognition site screening of two novel GT box binding proteins: a family of Sp1 related genes. Nucleic Acids Res (1992) 2.89
Altered morphology in transgenic tobacco plants that overproduce cytokinins in specific tissues and organs. Dev Biol (1992) 2.52
How does auxin turn on genes? Plant Physiol (1998) 2.38
Tissue-specific and organ-specific expression of soybean auxin-responsive transcripts GH3 and SAURs. Plant Cell (1991) 2.29
Genomic organization and promoter characterization of the gene encoding the human telomerase reverse transcriptase (hTERT). Gene (1999) 2.22
Complex organization of zein genes in maize. Gene (1981) 2.09
Oligomerization of RAR and AML1 transcription factors as a novel mechanism of oncogenic activation. Mol Cell (2000) 2.02
A transcriptionally active, covalently closed minichromosome of cauliflower mosaic virus DNA isolated from infected turnip leaves. Cell (1982) 2.02
Comparison of polyoma virus transcription in productively infected mouse cells and transformed rodent cell lines. Cold Spring Harb Symp Quant Biol (1980) 1.98
Identification of Arabidopsis histone deacetylase HDA6 mutants that affect transgene expression. Plant Cell (2001) 1.87
Active viral genes in transformed cells lie close to the nuclear cage. EMBO J (1982) 1.86
The ARF family of transcription factors and their role in plant hormone-responsive transcription. Cell Mol Life Sci (1998) 1.80
The polyoma virus 100K large T-antigen is not required for the maintenance of transformation. Virology (1980) 1.79
Transcription factor Sp3 is essential for post-natal survival and late tooth development. EMBO J (2000) 1.77
An inhibitor domain in Sp3 regulates its glutamine-rich activation domains. EMBO J (1996) 1.68
Sp3 is a bifunctional transcription regulator with modular independent activation and repression domains. J Biol Chem (1997) 1.67
Transcriptional regulation by the Sp family proteins. Int J Biochem Cell Biol (1997) 1.66
Untransformed rat cells containing free and integrated DNA of a polyoma nontransforming (Hr-t) mutant. Cell (1979) 1.65
On the basic structure of poly(glycerophosphate) lipoteichoic acids. Biochem Cell Biol (1990) 1.63
Repression of transcriptional activity at a distance by the evolutionarily conserved KRAB domain present in a subfamily of zinc finger proteins. Nucleic Acids Res (1994) 1.60
The uteroglobin gene region: hormonal regulation, repetitive elements and complete nucleotide sequence of the gene. Nucleic Acids Res (1983) 1.52
Transcription factor Sp3 is regulated by acetylation. Nucleic Acids Res (2001) 1.47
Identification and characterization of novel human endogenous retroviral sequences prefentially expressed in undifferentiated embryonal carcinoma cells. Nucleic Acids Res (1991) 1.46
LSD1-mediated demethylation of histone H3 lysine 4 triggers Myc-induced transcription. Oncogene (2010) 1.41
Isolation of cellular DNA sequences that allow expression of adjacent genes. Proc Natl Acad Sci U S A (1983) 1.40
Class A helix-loop-helix proteins are positive regulators of several cyclin-dependent kinase inhibitors' promoter activity and negatively affect cell growth. Cancer Res (2000) 1.35
Functional analyses of the transcription factor Sp4 reveal properties distinct from Sp1 and Sp3. J Biol Chem (1995) 1.34
Impaired ossification in mice lacking the transcription factor Sp3. Mech Dev (2001) 1.29
An auxin-inducible element in soybean SAUR promoters. Plant Physiol (1994) 1.29
Loss of functional large T-antigen and free viral genomes from cells transformed in vitro by polyoma virus after passage in vivo as tumor cells. J Virol (1981) 1.28
High Sp1/Sp3 ratios in epithelial cells during epithelial differentiation and cellular transformation correlate with the activation of the HPV-16 promoter. Virology (1996) 1.27
The ocs element in the soybean GH2/4 promoter is activated by both active and inactive auxin and salicylic acid analogues. Plant Mol Biol (1994) 1.27
Tissue-specific expression, hormonal regulation and 5'-flanking gene region of the rat Clara cell 10 kDa protein: comparison to rabbit uteroglobin. Nucleic Acids Res (1990) 1.27
Differential transcriptional regulation of c-myc promoter through the same DNA binding sites targeted by Sp1-like proteins. Oncogene (1995) 1.26
Upregulation of miR-21 by Ras in vivo and its role in tumor growth. Oncogene (2010) 1.25
Isolation of cDNAs encoding finger proteins and measurement of the corresponding mRNA levels during myeloid terminal differentiation. Nucleic Acids Res (1988) 1.25
Krüppel-associated box-mediated repression of RNA polymerase II promoters is influenced by the arrangement of basal promoter elements. Proc Natl Acad Sci U S A (1996) 1.23
Polyomavirus mutation that confers a cell-specific cis advantage for viral DNA replication. Mol Cell Biol (1985) 1.22
Sp1 trans-activation of cell cycle regulated promoters is selectively repressed by Sp3. Biochemistry (1995) 1.21
Transcriptional regulation by targeted recruitment of cyclin-dependent CDK9 kinase in vivo. Oncogene (1999) 1.20
Members of the Sp transcription factor family control transcription from the uteroglobin promoter. J Biol Chem (1995) 1.18
Binding of the ubiquitous cellular transcription factors Sp1 and Sp3 to the ZI domains in the Epstein-Barr virus lytic switch BZLF1 gene promoter. Virology (1997) 1.18
A novel member of the BTB/POZ family, PATZ, associates with the RNF4 RING finger protein and acts as a transcriptional repressor. J Biol Chem (2000) 1.16
Isovolemic hemodilution with a bovine hemoglobin-based oxygen carrier: effects on hemodynamics and oxygen transport in comparison with a nonoxygen-carrying volume substitute. J Cardiothorac Vasc Anesth (1997) 1.16
Mechanism of gene regulation by steroid hormones. J Steroid Biochem (1986) 1.14
Excision of polyoma virus genomes from chromosomal DNA by homologous recombination. Nature (1982) 1.10
Cloned genomic segments of Zea mays homologous to zein mRNAs. Gene (1981) 1.09
Complex phenotype of mice homozygous for a null mutation in the Sp4 transcription factor gene. Genes Cells (2001) 1.08
Use of a cellular polyadenylation signal by viral transcripts in polyoma virus transformed cells. Nucleic Acids Res (1982) 1.08
Transcriptional regulation of the SIS/PDGF-B gene in human osteosarcoma cells by the Sp family of transcription factors. J Biol Chem (1996) 1.07
Sp3 represses the Sp1-mediated transactivation of the human COL2A1 gene in primary and de-differentiated chondrocytes. J Biol Chem (2001) 1.07
Transcriptional activity of positive transcription elongation factor b kinase in vivo requires the C-terminal domain of RNA polymerase II. Gene (2000) 1.06
The soybean GH2/4 gene that encodes a glutathione S-transferase has a promoter that is activated by a wide range of chemical agents. Plant Physiol (1995) 1.04
Recruitment of human TBP selectively activates RNA polymerase II TATA-dependent promoters. J Biol Chem (1998) 1.04
The uteroglobin promoter contains a noncanonical estrogen responsive element. Mol Endocrinol (1990) 1.03
Maternal inheritance of plastids in Encephalartos Lehm. (Zamiaceae, Cycadales). Genome (2001) 1.02
Arabidopsis thaliana RNA polymerase II subunits related to yeast and human RPB5. Gene (1999) 1.02
Combinatorial action of HNF3 and Sp family transcription factors in the activation of the rabbit uteroglobin/CC10 promoter. J Biol Chem (1998) 1.01
Organization and expression of integrated polyoma virus DNA sequences in transformed rodent cells. Cold Spring Harb Symp Quant Biol (1980) 0.99
A role for Sp and helix-loop-helix transcription factors in the regulation of the human Id4 gene promoter activity. J Biol Chem (1998) 0.98
High efficiency of replication and expression of foreign genes in SV40-transformed human fibroblasts. EMBO J (1983) 0.98
Combined positron emission tomography/computed tomography in sunitinib therapy assessment of patients with metastatic renal cell carcinoma. Clin Oncol (R Coll Radiol) (2010) 0.98
Burning mouth syndrome (BMS): controlled open trial of the efficacy of alpha-lipoic acid (thioctic acid) on symptomatology. Oral Dis (2000) 0.97
Novel upstream elements and the TATA-box region mediate preferential transcription from the uteroglobin promoter in endometrial cells. Nucleic Acids Res (1991) 0.97
Distinct regions of cyclinT1 are required for binding to CDK9 and for recruitment to the HIV-1 Tat/TAR complex. J Cell Biochem Suppl (2001) 0.97
Functional interactions between Sp1 or Sp3 and the helicase-like transcription factor mediate basal expression from the human plasminogen activator inhibitor-1 gene. J Biol Chem (1999) 0.96
Sp3 represses transcription when tethered to promoter DNA or targeted to promoter proximal RNA. J Biol Chem (1996) 0.96
Identification of regulatory elements within the minimal promoter region of the human endogenous ERV9 proviruses: accurate transcription initiation is controlled by an Inr-like element. Nucleic Acids Res (1992) 0.96
The CDK9-associated cyclins T1 and T2 exert opposite effects on HIV-1 Tat activity. AIDS (1999) 0.95
Protein-DNA interactions at steroid hormone regulated genes. Endocr Res (1989) 0.95
trans-activation of cellular and viral promoters by a transforming nonkaryophilic simian virus 40 large T antigen. J Virol (1987) 0.95
Identification of new human repetitive sequences: characterization of the corresponding cDNAs and their expression in embryonal carcinoma cells. Nucleic Acids Res (1989) 0.93
A conserved TATA-less proximal promoter drives basal transcription from the urokinase-type plasminogen activator receptor gene. Blood (1995) 0.93
The transcription of B2 repeated sequences is regulated during the transition from quiescent to proliferative state in cultured rodent cells. FEBS Lett (1987) 0.92
Activation of major histocompatibility complex class I mRNA containing an Alu-like repeat in polyoma virus-transformed rat cells. Nature (1985) 0.92
The soybean SAUR open reading frame contains a cis element responsible for cycloheximide-induced mRNA accumulation. Plant Mol Biol (1994) 0.91
Regulation of the Clara cell secretory protein/uteroglobin promoter in lung. Ann N Y Acad Sci (2000) 0.91
Molecular cloning of ID4, a novel dominant negative helix-loop-helix human gene on chromosome 6p21.3-p22. Genomics (1995) 0.91
Regulation of viral and cellular promoter activity by polyomavirus early proteins. Nucleic Acids Res (1987) 0.90
C/EBP alpha and TTF-1 synergistically transactivate the Clara cell secretory protein gene. Ann N Y Acad Sci (2000) 0.89