Complex transcriptional effects of p63 isoforms: identification of novel activation and repression domains.

PubWeight™: 1.89‹?› | Rank: Top 3%

🔗 View Article (PMC 139859)

Published in Mol Cell Biol on December 01, 2002

Authors

Pamela Ghioni1, Fabrizio Bolognese, Pascal H G Duijf, Hans Van Bokhoven, Roberto Mantovani, Luisa Guerrini

Author Affiliations

1: Dipartimento di Genetica e Biologia dei Microrganismi, Milan, Italy.

Articles citing this

p63 is the molecular switch for initiation of an epithelial stratification program. Genes Dev (2004) 6.40

p63 regulates proliferation and differentiation of developmentally mature keratinocytes. Genes Dev (2006) 3.66

A regulatory feedback loop involving p63 and IRF6 links the pathogenesis of 2 genetically different human ectodermal dysplasias. J Clin Invest (2010) 1.73

Cooperation between the transcription factors p63 and IRF6 is essential to prevent cleft palate in mice. J Clin Invest (2010) 1.67

Differential recognition of response elements determines target gene specificity for p53 and p63. Mol Cell Biol (2005) 1.63

DeltaNp73beta is active in transactivation and growth suppression. Mol Cell Biol (2004) 1.56

New p63 targets in keratinocytes identified by a genome-wide approach. EMBO J (2006) 1.50

p53 Family and Cellular Stress Responses in Cancer. Front Oncol (2014) 1.33

Therapeutic prospects for p73 and p63: rising from the shadow of p53. Drug Resist Updat (2008) 1.32

The p53 circuit board. Biochim Biophys Acta (2012) 1.24

Claudin-1 is a p63 target gene with a crucial role in epithelial development. PLoS One (2008) 1.20

Identification and functional characterization of two new transcriptional variants of the human p63 gene. Nucleic Acids Res (2009) 1.19

An autoregulatory loop directs the tissue-specific expression of p63 through a long-range evolutionarily conserved enhancer. Mol Cell Biol (2006) 1.13

Mechanisms of transcriptional repression of cell-cycle G2/M promoters by p63. Nucleic Acids Res (2006) 1.13

p63 regulates glutaminase 2 expression. Cell Cycle (2013) 1.12

DeltaNp63 regulates stem cell dynamics in the mammalian olfactory epithelium. J Neurosci (2011) 1.12

Role of DeltaNp63gamma in epithelial to mesenchymal transition. J Biol Chem (2010) 1.04

Diverse p63 and p73 isoforms regulate Δ133p53 expression through modulation of the internal TP53 promoter activity. Cell Death Differ (2011) 1.03

DeltaNp63 knockdown mice: A mouse model for AEC syndrome. Am J Med Genet A (2009) 1.03

Constitutive expression of DeltaN-p63alpha isoform in human thymus and thymic epithelial tumours. Virchows Arch (2003) 1.01

Exome sequence identifies RIPK4 as the Bartsocas-Papas syndrome locus. Am J Hum Genet (2011) 1.00

Expression of novel p53 isoforms in oral lichen planus. Oral Oncol (2007) 0.98

Chemosensitivity is controlled by p63 modification with ubiquitin-like protein ISG15. J Clin Invest (2012) 0.96

Caspase-1 is a novel target of p63 in tumor suppression. Cell Death Dis (2013) 0.93

Human cataract mutations in EPHA2 SAM domain alter receptor stability and function. PLoS One (2012) 0.92

Cleavage of the transactivation-inhibitory domain of p63 by caspases enhances apoptosis. Proc Natl Acad Sci U S A (2007) 0.92

Role of p63 in Development, Tumorigenesis and Cancer Progression. Cancer Microenviron (2012) 0.91

Stxbp4 regulates DeltaNp63 stability by suppression of RACK1-dependent degradation. Mol Cell Biol (2009) 0.90

DeltaNp63 transcriptionally regulates ATM to control p53 Serine-15 phosphorylation. Mol Cancer (2010) 0.88

Role of p63 and the Notch pathway in cochlea development and sensorineural deafness. Proc Natl Acad Sci U S A (2013) 0.88

DLX5, FGF8 and the Pin1 isomerase control ΔNp63α protein stability during limb development: a regulatory loop at the basis of the SHFM and EEC congenital malformations. Hum Mol Genet (2014) 0.86

The microRNA feedback regulation of p63 in cancer progression. Oncotarget (2015) 0.86

A symphony of regulations centered on p63 to control development of ectoderm-derived structures. J Biomed Biotechnol (2011) 0.86

Pathway Regulation of p63, a Director of Epithelial Cell Fate. Front Endocrinol (Lausanne) (2015) 0.85

Differential PERP regulation by TP63 mutants provides insight into AEC pathogenesis. Am J Med Genet A (2009) 0.84

Differential effects of p63 mutants on transactivation of p53 and/or p63 responsive genes. Cell Res (2008) 0.84

Tissue-specific expression of p73 C-terminal isoforms in mice. Cell Cycle (2012) 0.84

Dysregulated ΔNp63α inhibits expression of Ink4a/arf, blocks senescence, and promotes malignant conversion of keratinocytes. PLoS One (2011) 0.83

Functional characterization of a novel TP63 mutation in a family with overlapping features of Rapp-Hodgkin/AEC/ADULT syndromes. Am J Med Genet A (2011) 0.83

Protein kinase C-dependent phosphorylation regulates the cell cycle-inhibitory function of the p73 carboxy terminus transactivation domain. Mol Cell Biol (2009) 0.82

Expression and regulation of the ΔN and TAp63 isoforms in salivary gland tumorigenesis clinical and experimental findings. Am J Pathol (2011) 0.82

p63 regulates cell proliferation and cell cycle progression‑associated genes in stromal cells of giant cell tumor of the bone. Int J Oncol (2012) 0.81

Inhibition of p63 transcriptional activity by p14ARF: functional and physical link between human ARF tumor suppressor and a member of the p53 family. Mol Cell Biol (2004) 0.81

∆N-P63α and TA-P63α exhibit intrinsic differences in transactivation specificities that depend on distinct features of DNA target sites. Oncotarget (2014) 0.81

Delineating Molecular Mechanisms of Squamous Tissue Homeostasis and Neoplasia: Focus on p63. J Skin Cancer (2013) 0.80

Polymorphic analysis of MHClinked Heat Shock Protein 70 genes: Their susceptibility and prognostic implication in Kangri cancer cases of Kashmiri population. Indian J Hum Genet (2009) 0.79

The Transcriptional Landscape of p53 Signalling Pathway. EBioMedicine (2017) 0.78

FGF8, c-Abl and p300 participate in a pathway that controls stability and function of the ΔNp63α protein. Hum Mol Genet (2015) 0.76

The p63 Gene Is Regulated by Grainyhead-like 2 (GRHL2) through Reciprocal Feedback and Determines the Epithelial Phenotype in Human Keratinocytes. J Biol Chem (2015) 0.76

The Regulation of Tumor Suppressor p63 by the Ubiquitin-Proteasome System. Int J Mol Sci (2016) 0.75

ΔNp63α expression induces loss of cell adhesion in triple-negative breast cancer cells. BMC Cancer (2016) 0.75

ΔNp63α Transcriptionally Regulates the Expression of CTEN That Is Associated with Prostate Cell Adhesion. PLoS One (2016) 0.75

Articles cited by this

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours. Nature (1992) 25.54

p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development. Nature (1999) 14.38

p63 is a p53 homologue required for limb and epidermal morphogenesis. Nature (1999) 13.21

p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities. Mol Cell (1998) 11.54

Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers. Cell (1997) 7.27

p63 identifies keratinocyte stem cells. Proc Natl Acad Sci U S A (2001) 6.07

Orchestrated response: a symphony of transcription factors for gene control. Genes Dev (2000) 5.86

p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours. Nature (2000) 5.83

Heterozygous germline mutations in the p53 homolog p63 are the cause of EEC syndrome. Cell (1999) 4.87

Post-transcriptional regulation of glyceraldehyde-3-phosphate-dehydrogenase gene expression in rat tissues. Nucleic Acids Res (1984) 4.79

Wild-type p53 can down-modulate the activity of various promoters. Proc Natl Acad Sci U S A (1991) 3.45

Cloning and functional analysis of human p51, which structurally and functionally resembles p53. Nat Med (1998) 3.23

Hay-Wells syndrome is caused by heterozygous missense mutations in the SAM domain of p63. Hum Mol Genet (2001) 2.95

Physical interaction with Yes-associated protein enhances p73 transcriptional activity. J Biol Chem (2001) 2.93

Predicting functions from protein sequences--where are the bottlenecks? Nat Genet (1998) 2.86

A subset of tumor-derived mutant forms of p53 down-regulate p63 and p73 through a direct interaction with the p53 core domain. Mol Cell Biol (2001) 2.69

P63 and P73: P53 mimics, menaces and more. Nat Rev Mol Cell Biol (2000) 2.64

The p53/p63/p73 family of transcription factors: overlapping and distinct functions. J Cell Sci (2000) 2.55

Twenty years of p53 research: structural and functional aspects of the p53 protein. Oncogene (1999) 2.43

p63alpha and DeltaNp63alpha can induce cell cycle arrest and apoptosis and differentially regulate p53 target genes. Oncogene (2001) 2.40

A functional p53-responsive intronic promoter is contained within the human mdm2 gene. Nucleic Acids Res (1995) 2.23

The p53 and Mdm2 families in cancer. Curr Opin Genet Dev (2002) 2.07

p63 Gene mutations in eec syndrome, limb-mammary syndrome, and isolated split hand-split foot malformation suggest a genotype-phenotype correlation. Am J Hum Genet (2001) 2.02

Regulation of the human hsp70 promoter by p53. Science (1993) 2.02

Split-hand/split-foot malformation is caused by mutations in the p63 gene on 3q27. Am J Hum Genet (2000) 1.98

Analysis of p53 mutants for transcriptional activity. Mol Cell Biol (1991) 1.73

How to activate p53. Curr Biol (2000) 1.70

Sp3 is a bifunctional transcription regulator with modular independent activation and repression domains. J Biol Chem (1997) 1.67

Different members of the Sp1 multigene family exert opposite transcriptional regulation of the long terminal repeat of HIV-1. Nucleic Acids Res (1994) 1.65

p73 and p63 are homotetramers capable of weak heterotypic interactions with each other but not with p53. J Biol Chem (1999) 1.53

Solution structure of a conserved C-terminal domain of p73 with structural homology to the SAM domain. EMBO J (1999) 1.43

p53 family update: p73 and p63 develop their own identities. Cell Growth Differ (2001) 1.36

Promoter specificity and stability control of the p53-related protein p73. Oncogene (1999) 1.36

The tumour suppressor protein p53 can repress transcription of cyclin B. Nucleic Acids Res (2000) 1.36

New p73 variants with altered C-terminal structures have varied transcriptional activities. Oncogene (1999) 1.30

p63 and p73 transactivate differentiation gene promoters in human keratinocytes. Biochem Biophys Res Commun (2000) 1.28

Regulation and function of the p53-related proteins: same family, different rules. Trends Cell Biol (2000) 1.27

The human MDM2 oncoprotein increases the transcriptional activity and the protein level of the p53 homolog p63. J Biol Chem (2001) 1.22

p53 Family members p63 and p73 are SAM domain-containing proteins. Protein Sci (1999) 1.19

Role of chromatin and Xenopus laevis heat shock transcription factor in regulation of transcription from the X. laevis hsp70 promoter in vivo. Mol Cell Biol (1995) 1.16

p51A (TAp63gamma), a p53 homolog, accumulates in response to DNA damage for cell regulation. Oncogene (2000) 1.12

NF-Y binding to twin CCAAT boxes: role of Q-rich domains and histone fold helices. J Mol Biol (1999) 1.05

Deletion of the COOH-terminal region of p73alpha enhances both its transactivation function and DNA-binding activity but inhibits induction of apoptosis in mammalian cells. Cancer Res (1999) 1.04

Identification of a transactivation activity in the COOH-terminal region of p73 which is impaired in the naturally occurring mutants found in human neuroblastomas. Cancer Res (1999) 1.00

p63 and p73: old members of a new family. Biochim Biophys Acta (2000) 0.95

p53 Homologue p63 represses epidermal growth factor receptor expression. J Biol Chem (2001) 0.94

p53 tumor-suppressor gene: clues to molecular carcinogenesis. J Cell Physiol (1997) 0.93

Identification and tissue distribution of novel KET/p63 splice variants. FEBS Lett (2001) 0.88

Differential DNA sequence specificity and regulation of HIV-1 enhancer activity by cRel-RelA transcription factor. J Biol Chem (1994) 0.84

Lack of homozygously inactivated p73 in single-copy MYCN primary neuroblastomas and neuroblastoma cell lines. Neoplasia (1999) 0.83

Articles by these authors

Np95 is a histone-binding protein endowed with ubiquitin ligase activity. Mol Cell Biol (2004) 2.35

Mad2 is a critical mediator of the chromosome instability observed upon Rb and p53 pathway inhibition. Cancer Cell (2011) 2.29

Direct p53 transcriptional repression: in vivo analysis of CCAAT-containing G2/M promoters. Mol Cell Biol (2005) 2.13

The NF-YB/NF-YC structure gives insight into DNA binding and transcription regulation by CCAAT factor NF-Y. J Biol Chem (2002) 2.03

Itch/AIP4 associates with and promotes p63 protein degradation. Cell Cycle (2006) 1.91

A perspective of promoter architecture from the CCAAT box. Cell Cycle (2009) 1.86

The THAP-zinc finger protein THAP1 regulates endothelial cell proliferation through modulation of pRB/E2F cell-cycle target genes. Blood (2006) 1.81

A C-terminal inhibitory domain controls the activity of p63 by an intramolecular mechanism. Mol Cell Biol (2002) 1.73

A regulatory feedback loop involving p63 and IRF6 links the pathogenesis of 2 genetically different human ectodermal dysplasias. J Clin Invest (2010) 1.73

CDKL5 belongs to the same molecular pathway of MeCP2 and it is responsible for the early-onset seizure variant of Rett syndrome. Hum Mol Genet (2005) 1.72

DeltaNp63 regulates thymic development through enhanced expression of FgfR2 and Jag2. Proc Natl Acad Sci U S A (2007) 1.70

Homeodomain protein Dlx3 induces phosphorylation-dependent p63 degradation. Cell Cycle (2009) 1.62

Mutations in the polyglutamine binding protein 1 gene cause X-linked mental retardation. Nat Genet (2003) 1.61

Dynamic recruitment of NF-Y and histone acetyltransferases on cell-cycle promoters. J Biol Chem (2003) 1.60

The promoters of human cell cycle genes integrate signals from two tumor suppressive pathways during cellular transformation. Mol Syst Biol (2005) 1.60

Regulation of novel members of the Arabidopsis thaliana CCAAT-binding nuclear factor Y subunits. Gene (2002) 1.58

TRIM8 modulates p53 activity to dictate cell cycle arrest. Cell Cycle (2012) 1.56

Regulation of Dlx5 and Dlx6 gene expression by p63 is involved in EEC and SHFM congenital limb defects. Development (2008) 1.55

Pin1 links the activities of c-Abl and p300 in regulating p73 function. Mol Cell (2004) 1.55

Trabectedin (ET-743) promotes differentiation in myxoid liposarcoma tumors. Mol Cancer Ther (2009) 1.52

Mutations in the ZNF41 gene are associated with cognitive deficits: identification of a new candidate for X-linked mental retardation. Am J Hum Genet (2003) 1.52

New p63 targets in keratinocytes identified by a genome-wide approach. EMBO J (2006) 1.50

Mutation screening in 86 known X-linked mental retardation genes by droplet-based multiplex PCR and massive parallel sequencing. Hugo J (2010) 1.50

NF-Y and the transcriptional activation of CCAAT promoters. Crit Rev Biochem Mol Biol (2011) 1.49

Transcription factor SOX3 is involved in X-linked mental retardation with growth hormone deficiency. Am J Hum Genet (2002) 1.45

DeltaNp63alpha up-regulates the Hsp70 gene in human cancer. Cancer Res (2005) 1.44

The promiscuous life of plant NUCLEAR FACTOR Y transcription factors. Plant Cell (2012) 1.43

Single nucleosome ChIPs identify an extensive switch of acetyl marks on cell cycle promoters. Cell Cycle (2010) 1.43

Developmental factor IRF6 exhibits tumor suppressor activity in squamous cell carcinomas. Proc Natl Acad Sci U S A (2011) 1.42

The histone-like NF-Y is a bifunctional transcription factor. Mol Cell Biol (2008) 1.40

Sequence-specific transcription factor NF-Y displays histone-like DNA binding and H2B-like ubiquitination. Cell (2013) 1.33

Transcriptional activation of the cyclin A gene by the architectural transcription factor HMGA2. Mol Cell Biol (2003) 1.32

Mutations in the human TBX4 gene cause small patella syndrome. Am J Hum Genet (2004) 1.31

Chromatin immunoprecipitation (ChIP) on chip experiments uncover a widespread distribution of NF-Y binding CCAAT sites outside of core promoters. J Biol Chem (2005) 1.30

Cdk2-dependent phosphorylation of the NF-Y transcription factor and its involvement in the p53-p21 signaling pathway. J Biol Chem (2003) 1.23

Dynamic recruitment of transcription factors and epigenetic changes on the ER stress response gene promoters. Nucleic Acids Res (2006) 1.23

Ternary complex formation between MADS-box transcription factors and the histone fold protein NF-YB. J Biol Chem (2002) 1.20

Claudin-1 is a p63 target gene with a crucial role in epithelial development. PLoS One (2008) 1.20

Requirement for down-regulation of the CCAAT-binding activity of the NF-Y transcription factor during skeletal muscle differentiation. Mol Biol Cell (2003) 1.19

Repression of new p53 targets revealed by ChIP on chip experiments. Cell Cycle (2006) 1.18

Interactions between p300 and multiple NF-Y trimers govern cyclin B2 promoter function. J Biol Chem (2002) 1.18

Functional consequences of mutations in CDKL5, an X-linked gene involved in infantile spasms and mental retardation. J Biol Chem (2006) 1.18

DNA damage promotes histone deacetylase 4 nuclear localization and repression of G2/M promoters, via p53 C-terminal lysines. J Biol Chem (2005) 1.18

NF-Y coassociates with FOS at promoters, enhancers, repetitive elements, and inactive chromatin regions, and is stereo-positioned with growth-controlling transcription factors. Genome Res (2013) 1.15

NF-Y recruitment of TFIID, multiple interactions with histone fold TAF(II)s. J Biol Chem (2001) 1.15

Mechanisms of transcriptional repression of cell-cycle G2/M promoters by p63. Nucleic Acids Res (2006) 1.13

The protein stability and transcriptional activity of p63alpha are regulated by SUMO-1 conjugation. Cell Cycle (2005) 1.12

Differential altered stability and transcriptional activity of ΔNp63 mutants in distinct ectodermal dysplasias. J Cell Sci (2011) 1.11

Transcriptional network of p63 in human keratinocytes. PLoS One (2009) 1.10

MDM2 and Fbw7 cooperate to induce p63 protein degradation following DNA damage and cell differentiation. J Cell Sci (2010) 1.09

Cell cycle regulation of NF-YC nuclear localization. Cell Cycle (2004) 1.09

A distal CCAAT/NUCLEAR FACTOR Y complex promotes chromatin looping at the FLOWERING LOCUS T promoter and regulates the timing of flowering in Arabidopsis. Plant Cell (2014) 1.08

Regulation of the cyclin-dependent kinase inhibitor p57Kip2 expression by p63. Cell Cycle (2005) 1.07

Hoxd13 binds in vivo and regulates the expression of genes acting in key pathways for early limb and skeletal patterning. Dev Biol (2008) 1.07

Posttranslational regulation of NF-YA modulates NF-Y transcriptional activity. Mol Biol Cell (2008) 1.06

PLEXIN-D1, a novel plexin family member, is expressed in vascular endothelium and the central nervous system during mouse embryogenesis. Dev Dyn (2002) 1.05

Hitting the numbers: the emerging network of p63 targets. Cell Cycle (2007) 1.03

A novel translation re-initiation mechanism for the p63 gene revealed by amino-terminal truncating mutations in Rapp-Hodgkin/Hay-Wells-like syndromes. Hum Mol Genet (2008) 1.02

Homeobox gene Dlx3 is regulated by p63 during ectoderm development: relevance in the pathogenesis of ectodermal dysplasias. Development (2007) 1.02

Interaction between the inner nuclear membrane lamin B receptor and the heterochromatic methyl binding protein, MeCP2. Exp Cell Res (2009) 1.01

Gain-of-function p53 mutants have widespread genomic locations partially overlapping with p63. Oncotarget (2012) 1.00

Unique features of the mode of action of ET-743. Oncologist (2002) 0.97

The NF-Y/p53 liaison: well beyond repression. Biochim Biophys Acta (2011) 0.97

Identification of new p63 targets in human keratinocytes. Cell Cycle (2006) 0.97

DNA compaction by the nuclear factor-Y. Biophys J (2007) 0.97

Interactions and CCAAT-binding of Arabidopsis thaliana NF-Y subunits. PLoS One (2012) 0.95

Retracted NF-Y substitutes H2A-H2B on active cell-cycle promoters: recruitment of CoREST-KDM1 and fine-tuning of H3 methylations. Nucleic Acids Res (2008) 0.94

Cyclin B1 transcription is enhanced by the p300 coactivator and regulated during the cell cycle by a CHR-dependent repression mechanism. FEBS Lett (2003) 0.93

Embryonic stem cells as an ectodermal cellular model of human p63-related dysplasia syndromes. Biochem Biophys Res Commun (2010) 0.93

Reciprocal regulation of p63 by C/EBP delta in human keratinocytes. BMC Mol Biol (2007) 0.91

An NF-Y-dependent switch of positive and negative histone methyl marks on CCAAT promoters. PLoS One (2008) 0.91

An etiologic regulatory mutation in IRF6 with loss- and gain-of-function effects. Hum Mol Genet (2014) 0.89

Inv(X)(p21.1;q22.1) in a man with mental retardation, short stature, general muscle wasting, and facial dysmorphism: clinical study and mutation analysis of the NXF5 gene. Am J Med Genet A (2003) 0.89

Neurologic aspects of MECP2 gene duplication in male patients. Pediatr Neurol (2009) 0.89

The short isoform of NF-YA belongs to the embryonic stem cell transcription factor circuitry. Stem Cells (2012) 0.88

NF-Y regulates the antisense promoter, bidirectional silencing, and differential epigenetic marks of the Kcnq1 imprinting control region. J Biol Chem (2004) 0.88

BMP-mediated functional cooperation between Dlx5;Dlx6 and Msx1;Msx2 during mammalian limb development. PLoS One (2013) 0.88

Selective effects of the anticancer drug Yondelis (ET-743) on cell-cycle promoters. Mol Pharmacol (2005) 0.87

Inhibition of DNA binding of the NF-Y transcription factor by the pyrrolobenzodiazepine-polyamide conjugate GWL-78. Mol Cancer Ther (2008) 0.87

The TFIID subunit TAF4 regulates keratinocyte proliferation and has cell-autonomous and non-cell-autonomous tumour suppressor activity in mouse epidermis. Development (2007) 0.87

A p38-dependent pathway regulates DeltaNp63 DNA binding to p53-dependent promoters in UV-induced apoptosis of keratinocytes. Oncogene (2005) 0.86

Identification of DeltaNp63alpha protein interactions by mass spectrometry. J Proteome Res (2010) 0.85

The role of inflammation and matrix metalloproteinases in equine endometriosis. J Vet Sci (2012) 0.85

Polymorphic NF-Y dependent regulation of human nicotine C-oxidase (CYP2A6). Pharmacogenetics (2004) 0.84

Cross-talks in the p53 family: deltaNp63 is an anti-apoptotic target for deltaNp73alpha and p53 gain-of-function mutants. Cell Cycle (2006) 0.83

RNF4 is a coactivator for nuclear factor Y on GTP cyclohydrolase I proximal promoter. Mol Pharmacol (2004) 0.81

Inhibition of p63 transcriptional activity by p14ARF: functional and physical link between human ARF tumor suppressor and a member of the p53 family. Mol Cell Biol (2004) 0.81

The HDAC inhibitor Givinostat modulates the hematopoietic transcription factors NFE2 and C-MYB in JAK2(V617F) myeloproliferative neoplasm cells. Exp Hematol (2012) 0.81

NF-Y recruits Ash2L to impart H3K4 trimethylation on CCAAT promoters. PLoS One (2011) 0.81

Modulation of topoisomerase IIalpha expression by a DNA sequence-specific polyamide. Mol Cancer Ther (2007) 0.81

A novel intragenic sequence enhances initiator-dependent transcription in human embryonic kidney 293 cells. J Biol Chem (2002) 0.80

An acetylation-mono-ubiquitination switch on lysine 120 of H2B. Epigenetics (2011) 0.80

Reconstitution of TIMP-2 expression in SH-SY5Y neuroblastoma cells by 5-azacytidine is mediated transcriptionally by NF-Y through an inverted CCAAT site. Exp Cell Res (2003) 0.80

NF-Y affects histone acetylation and H2A.Z deposition in cell cycle promoters. Epigenetics (2011) 0.79

C/EBPδ gene targets in human keratinocytes. PLoS One (2010) 0.79

Characterization of the human EDF-1 minimal promoter: involvement of NFY and Sp1 in the regulation of basal transcription. Gene (2006) 0.79

Large scale RNAi screen reveals that the inhibitor of DNA binding 2 (ID2) protein is repressed by p53 family member p63 and functions in human keratinocyte differentiation. J Biol Chem (2011) 0.79