Replacement of Asp333 with Asn by site-directed mutagenesis changes the substrate specificity of Escherichia coli adenylosuccinate synthetase from guanosine 5'-triphosphate to xanthosine 5'-triphosphate.

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Published in J Biol Chem on September 30, 1994

Authors

C Kang1, N Sun, R B Honzatko, H J Fromm

Author Affiliations

1: Department of Biochemistry and Biophysics, Iowa State University, Ames 50010.

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