Published in J Cell Biol on October 01, 1994
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The decision to enter mitosis: feedback and redundancy in the mitotic entry network. J Cell Biol (2009) 3.48
Molecular interaction map of the mammalian cell cycle control and DNA repair systems. Mol Biol Cell (1999) 3.41
A centrosomal function for the human Nek2 protein kinase, a member of the NIMA family of cell cycle regulators. EMBO J (1998) 3.04
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c-Myc regulates cyclin D-Cdk4 and -Cdk6 activity but affects cell cycle progression at multiple independent points. Mol Cell Biol (1999) 2.50
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A kinase-deficient transcription factor TFIIH is functional in basal and activated transcription. Proc Natl Acad Sci U S A (1995) 2.20
A dominant-negative cyclin D1 mutant prevents nuclear import of cyclin-dependent kinase 4 (CDK4) and its phosphorylation by CDK-activating kinase. Mol Cell Biol (1997) 2.14
MAT1 ('menage à trois') a new RING finger protein subunit stabilizing cyclin H-cdk7 complexes in starfish and Xenopus CAK. EMBO J (1995) 1.74
Identification of human cyclin-dependent kinase 8, a putative protein kinase partner for cyclin C. Proc Natl Acad Sci U S A (1995) 1.73
Human Tousled like kinases are targeted by an ATM- and Chk1-dependent DNA damage checkpoint. EMBO J (2003) 1.67
In vitro assembly of a functional human CDK7-cyclin H complex requires MAT1, a novel 36 kDa RING finger protein. EMBO J (1995) 1.66
Flavopiridol: the first cyclin-dependent kinase inhibitor in human clinical trials. Invest New Drugs (1999) 1.63
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Identification of a cdk-activating kinase in fission yeast. EMBO J (1995) 1.45
XPB and XPD helicases in TFIIH orchestrate DNA duplex opening and damage verification to coordinate repair with transcription and cell cycle via CAK kinase. DNA Repair (Amst) (2011) 1.45
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Drosophila Cdk8, a kinase partner of cyclin C that interacts with the large subunit of RNA polymerase II. Mol Biol Cell (1996) 1.35
p53 is phosphorylated by CDK7-cyclin H in a p36MAT1-dependent manner. Mol Cell Biol (1997) 1.31
Spatial positive feedback at the onset of mitosis. Cell (2012) 1.26
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The molecular mechanism of mitotic inhibition of TFIIH is mediated by phosphorylation of CDK7. Genes Dev (1998) 1.22
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Phosphorylation of the Par-1 polarity kinase by protein kinase D regulates 14-3-3 binding and membrane association. Proc Natl Acad Sci U S A (2008) 1.08
Regulation of CDK4. Cell Div (2006) 1.06
The cdk7-cyclin H-MAT1 complex associated with TFIIH is localized in coiled bodies. Mol Biol Cell (1997) 1.01
Differential regulation of cyclin-dependent kinase 4 (CDK4) and CDK6, evidence that CDK4 might not be activated by CDK7, and design of a CDK6 activating mutation. Mol Cell Biol (2009) 1.00
Regulated activating Thr172 phosphorylation of cyclin-dependent kinase 4(CDK4): its relationship with cyclins and CDK "inhibitors". Mol Cell Biol (2006) 0.98
Cyclin E and SV40 small T antigen cooperate to bypass quiescence and contribute to transformation by activating CDK2 in human fibroblasts. J Biol Chem (2008) 0.96
CDK4 T172 phosphorylation is central in a CDK7-dependent bidirectional CDK4/CDK2 interplay mediated by p21 phosphorylation at the restriction point. PLoS Genet (2013) 0.96
Dominant-negative mutants reveal a role for the Cdk7 kinase at the mid-blastula transition in Drosophila embryos. EMBO J (2000) 0.96
Activating phosphorylation of the Saccharomyces cerevisiae cyclin-dependent kinase, cdc28p, precedes cyclin binding. Mol Biol Cell (2000) 0.95
Cyclic AMP inhibits the proliferation of thyroid carcinoma cell lines through regulation of CDK4 phosphorylation. Mol Biol Cell (2008) 0.95
Changes in oscillatory dynamics in the cell cycle of early Xenopus laevis embryos. PLoS Biol (2014) 0.92
Functional interactions between herpesvirus oncoprotein MEQ and cell cycle regulator CDK2. J Virol (1999) 0.91
Cyclins and cell cycle control in cancer and disease. Genes Cancer (2012) 0.90
A novel partner for D-type cyclins: protein kinase A-anchoring protein AKAP95. Biochem J (2004) 0.90
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MAT1-modulated CAK activity regulates cell cycle G(1) exit. Mol Cell Biol (2001) 0.89
Coupling of T161 and T14 phosphorylations protects cyclin B-CDK1 from premature activation. Mol Biol Cell (2011) 0.89
Density-dependent growth inhibition of fibroblasts ectopically expressing p27(kip1). Mol Biol Cell (2000) 0.87
Modulation of cell cycle control during oocyte-to-embryo transitions. EMBO J (2013) 0.87
The rice cyclin-dependent kinase-activating kinase R2 regulates S-phase progression. Plant Cell (2002) 0.85
Transforming growth factor beta(1) selectively inhibits the cyclic AMP-dependent proliferation of primary thyroid epithelial cells by preventing the association of cyclin D3-cdk4 with nuclear p27(kip1). Mol Biol Cell (2000) 0.85
CAK-independent activation of CDK6 by a viral cyclin. Mol Biol Cell (2001) 0.84
Cyclin-stimulated binding of Cks proteins to cyclin-dependent kinases. Mol Cell Biol (1998) 0.84
Tumor extension and cell proliferation in adenocarcinomas of the lung. Am J Pathol (1999) 0.84
Identification and Functional Characterisation of CRK12:CYC9, a Novel Cyclin-Dependent Kinase (CDK)-Cyclin Complex in Trypanosoma brucei. PLoS One (2013) 0.83
The CDK-activating kinase (CAK) Csk1 is required for normal levels of homologous recombination and resistance to DNA damage in fission yeast. PLoS One (2008) 0.83
Functional analysis of the Cdk7.cyclin H.Mat1 complex in mouse embryonic stem cells and embryos. J Biol Chem (2010) 0.83
An RNA polymerase II complex containing all essential initiation factors binds to the activation domain of PAR leucine zipper transcription factor thyroid embryonic factor. Mol Cell Biol (1999) 0.82
Inhibition of PI3K/Akt pathway impairs G2/M transition of cell cycle in late developing progenitors of the avian embryo retina. PLoS One (2013) 0.82
Mat1 inhibits peroxisome proliferator-activated receptor gamma-mediated adipocyte differentiation. Mol Cell Biol (2008) 0.82
Sparstolonin B inhibits pro-angiogenic functions and blocks cell cycle progression in endothelial cells. PLoS One (2013) 0.80
Involvement of cyclins in cell proliferation and their clinical implications in soft tissue smooth muscle tumors. Am J Pathol (2000) 0.78
Unique Regulatory Mechanisms for the Human Embryonic Stem Cell Cycle. J Cell Physiol (2016) 0.75
JNKs function as CDK4-activating kinases by phosphorylating CDK4 and p21. Oncogene (2017) 0.75
WAF1, a potential mediator of p53 tumor suppression. Cell (1993) 38.72
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Tyrosine phosphorylation of the fission yeast cdc2+ protein kinase regulates entry into mitosis. Nature (1989) 11.90
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