Published in Oncogene on November 01, 1994
Nuclear factor (NF)-kappa B2 (p100/p52) is required for normal splenic microarchitecture and B cell-mediated immune responses. J Exp Med (1998) 2.78
Fibroblasts as sentinel cells. Synthesis of chemokines and regulation of inflammation. Am J Pathol (1997) 2.47
RelB is required for Peyer's patch development: differential regulation of p52-RelB by lymphotoxin and TNF. EMBO J (2003) 2.17
Gastric hyperplasia and increased proliferative responses of lymphocytes in mice lacking the COOH-terminal ankyrin domain of NF-kappaB2. J Exp Med (1997) 2.13
Perturbation of the T lymphocyte lineage in transgenic mice expressing a constitutive repressor of nuclear factor (NF)-kappaB. J Exp Med (1997) 1.85
Chronic inflammation and susceptibility to bacterial infections in mice lacking the polypeptide (p)105 precursor (NF-kappaB1) but expressing p50. J Exp Med (1998) 1.79
Differential requirement for Rel/nuclear factor kappa B family members in natural killer T cell development. J Exp Med (2003) 1.77
The prognostic impact of NF-kappaB p105, vimentin, E-cadherin and Par6 expression in epithelial and stromal compartment in non-small-cell lung cancer. Br J Cancer (2008) 1.50
An essential role for nuclear factor kappaB in promoting double positive thymocyte apoptosis. J Exp Med (1999) 1.44
Notch3 and pre-TCR interaction unveils distinct NF-kappaB pathways in T-cell development and leukemia. EMBO J (2006) 1.37
A role for TGFbeta1 in langerhans cell biology. Further characterization of the epidermal Langerhans cell defect in TGFbeta1 null mice. J Clin Invest (1997) 1.35
NIK-dependent RelB activation defines a unique signaling pathway for the development of V alpha 14i NKT cells. J Exp Med (2003) 1.33
p50-NF-kappaB complexes partially compensate for the absence of RelB: severely increased pathology in p50(-/-)relB(-/-) double-knockout mice. J Exp Med (1997) 1.32
RelB modulation of IkappaBalpha stability as a mechanism of transcription suppression of interleukin-1alpha (IL-1alpha), IL-1beta, and tumor necrosis factor alpha in fibroblasts. Mol Cell Biol (1999) 1.28
Constitutive expression of Bc1-3 in thymocytes increases the DNA binding of NF-kappaB1 (p50) homodimers in vivo. Mol Cell Biol (1996) 1.24
Apoptosis of nur77/N10-transgenic thymocytes involves the Fas/Fas ligand pathway. Proc Natl Acad Sci U S A (1996) 1.22
Overexpression of RelA in transgenic mouse thymocytes: specific increase in levels of the inhibitor protein I kappa B alpha. Mol Cell Biol (1995) 1.16
The v-rel oncogene promotes malignant T-cell leukemia/lymphoma in transgenic mice. EMBO J (1996) 1.12
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IRF-4 and c-Rel expression in antiviral-resistant adult T-cell leukemia/lymphoma. Blood (2007) 1.06
Multiple hemopoietic defects and lymphoid hyperplasia in mice lacking the transcriptional activation domain of the c-Rel protein. J Exp Med (1998) 1.04
The c-Rel Transcription Factor in Development and Disease. Genes Cancer (2011) 1.01
Induction of the RelB NF-kappaB subunit by the cytomegalovirus IE1 protein is mediated via Jun kinase and c-Jun/Fra-2 AP-1 complexes. J Virol (2005) 1.00
NF-kB inhibitor blocks B cell development at two checkpoints. Med Immunol (2004) 1.00
RelA/p65 regulation of IkappaBbeta. Mol Cell Biol (2005) 0.99
Differential RelA- and RelB-dependent gene transcription in LTbetaR-stimulated mouse embryonic fibroblasts. BMC Genomics (2008) 0.99
NF-kappaB2 is required for the control of autoimmunity by regulating the development of medullary thymic epithelial cells. J Biol Chem (2006) 0.98
High-level replication of human immunodeficiency virus in thymocytes requires NF-kappaB activation through interaction with thymic epithelial cells. J Virol (1999) 0.95
Concurrent proinflammatory and apoptotic activity of a Helicobacter pylori protein (HP986) points to its role in chronic persistence. PLoS One (2011) 0.95
Hypercapnia induces cleavage and nuclear localization of RelB protein, giving insight into CO2 sensing and signaling. J Biol Chem (2012) 0.92
Sequences between the enhancer and promoter in the long terminal repeat affect murine leukemia virus pathogenicity and replication in the thymus. J Virol (1999) 0.88
Nuclear factor kappa B activation occurs in the amnion prior to labour onset and modulates the expression of numerous labour associated genes. PLoS One (2012) 0.88
RNAi-mediated c-Rel silencing leads to apoptosis of B cell tumor cells and suppresses antigenic immune response in vivo. PLoS One (2009) 0.86
The nfkb1 promoter is controlled by proteins of the Ets family. Mol Biol Cell (1997) 0.84
Promoter activity 5' of Dbeta2 is coordinated by E47, Runx1, and GATA-3. Mol Immunol (2009) 0.83
IkappaBalpha overexpression delays tumor formation in v-rel transgenic mice. J Exp Med (1997) 0.80
p100 Deficiency is insufficient for full activation of the alternative NF-κB pathway: TNF cooperates with p52-RelB in target gene transcription. PLoS One (2012) 0.80
The NF-κB subunit c-Rel regulates Bach2 tumour suppressor expression in B-cell lymphoma. Oncogene (2015) 0.80
Differential utilization of NF-kappaB RELA and RELB in response to extracellular versus intracellular polyIC stimulation in HT1080 cells. BMC Immunol (2011) 0.79
Identification of nucleotide sequences that regulate transcription of the MCF13 murine leukemia virus long terminal repeat in activated T cells. J Virol (1997) 0.79
c-Rel deficiency increases caspase-4 expression and leads to ER stress and necrosis in EBV-transformed cells. PLoS One (2011) 0.77
Constitutive nuclear NF kappa B/rel DNA-binding activity of rat thymocytes is increased by stimuli that promote apoptosis, but not inhibited by pyrrolidine dithiocarbamate. Biochem J (1995) 0.77
BOR-syndrome-associated Eya1 mutations lead to enhanced proteasomal degradation of Eya1 protein. PLoS One (2014) 0.75
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Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis. Nature (2001) 7.06
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Transcriptional activation of c-jun during the G0/G1 transition in mouse fibroblasts. Nature (1988) 5.04
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The product of a novel growth factor activated gene, fos B, interacts with JUN proteins enhancing their DNA binding activity. EMBO J (1989) 4.27
Two mouse genes encoding potential transcription factors with identical DNA-binding domains are activated by growth factors in cultured cells. Proc Natl Acad Sci U S A (1988) 4.08
RelB, a new Rel family transcription activator that can interact with p50-NF-kappa B. Mol Cell Biol (1992) 4.03
A gene encoding a protein with zinc fingers is activated during G0/G1 transition in cultured cells. EMBO J (1988) 3.98
A novel mitogen-inducible gene product related to p50/p105-NF-kappa B participates in transactivation through a kappa B site. Mol Cell Biol (1992) 3.63
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The jun and fos protein families are both required for cell cycle progression in fibroblasts. Mol Cell Biol (1991) 3.08
Cloning and sequence of the human nuclear protein cyclin: homology with DNA-binding proteins. Proc Natl Acad Sci U S A (1987) 3.05
The leucine repeat motif in Fos protein mediates complex formation with Jun/AP-1 and is required for transformation. Cell (1989) 2.84
An enzymatic assay reveals that proteins destined for the apical or basolateral domains of an epithelial cell line share the same late Golgi compartments. EMBO J (1985) 2.78
Nuclear factor (NF)-kappa B2 (p100/p52) is required for normal splenic microarchitecture and B cell-mediated immune responses. J Exp Med (1998) 2.78
Altered gene expression in neurons during programmed cell death: identification of c-jun as necessary for neuronal apoptosis. J Cell Biol (1994) 2.75
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Changes in the nuclear distribution of cyclin (PCNA) but not its synthesis depend on DNA replication. EMBO J (1985) 2.28
Rapid induction in regenerating liver of RL/IF-1 (an I kappa B that inhibits NF-kappa B, RelB-p50, and c-Rel-p50) and PHF, a novel kappa B site-binding complex. Mol Cell Biol (1992) 2.27
Disruption of the erp/mkp-1 gene does not affect mouse development: normal MAP kinase activity in ERP/MKP-1-deficient fibroblasts. Oncogene (1996) 2.20
Segment-specific expression of a zinc-finger gene in the developing nervous system of the mouse. Nature (1989) 2.18
Gastric hyperplasia and increased proliferative responses of lymphocytes in mice lacking the COOH-terminal ankyrin domain of NF-kappaB2. J Exp Med (1997) 2.13
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The presence of dialkylphosphates in fresh fruit juices: implication for organophosphorus pesticide exposure and risk assessments. J Toxicol Environ Health A (2005) 2.05
Characterization of a mouse multigene family that encodes zinc finger structures. Mol Cell Biol (1988) 2.05
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Structure, mapping and expression of a growth factor inducible gene encoding a putative nuclear hormonal binding receptor. EMBO J (1989) 1.98
Cloning and functional expression of mCCR2, a murine receptor for the C-C chemokines JE and FIC. J Biol Chem (1996) 1.94
The NFAT-1 DNA binding complex in activated T cells contains Fra-1 and JunB. Mol Cell Biol (1993) 1.94
Synthesis of the nuclear protein cyclin (PCNA) and its relationship with DNA replication. Exp Cell Res (1986) 1.92
Impaired macrophage function and enhanced T cell-dependent immune response in mice lacking CCR5, the mouse homologue of the major HIV-1 coreceptor. J Immunol (1998) 1.92
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Structure, mapping, and expression of fisp-12, a growth factor-inducible gene encoding a secreted cysteine-rich protein. Cell Growth Differ (1991) 1.80
Chronic inflammation and susceptibility to bacterial infections in mice lacking the polypeptide (p)105 precursor (NF-kappaB1) but expressing p50. J Exp Med (1998) 1.79
Changes in cyclin/proliferating cell nuclear antigen distribution during DNA repair synthesis. J Cell Biol (1988) 1.79
Cyclin: a nuclear protein whose level correlates directly with the proliferative state of normal as well as transformed cells. Leuk Res (1984) 1.79
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High incidence of allograft cirrhosis in hepatitis C virus genotype 1b infection following transplantation: relationship with rejection episodes. Hepatology (1999) 1.76
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Both N- and C-terminal domains of RelB are required for full transactivation: role of the N-terminal leucine zipper-like motif. Mol Cell Biol (1993) 1.46
Hyperlipidemia in liver transplant recipients: prevalence and risk factors. Liver Transpl Surg (1997) 1.46
Functional redundancy of the nuclear factor kappa B inhibitors I kappa B alpha and I kappa B beta. J Exp Med (1998) 1.45
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Wounding a fibroblast monolayer results in the rapid induction of the c-fos proto-oncogene. EMBO J (1986) 1.42
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[Rapid and slow progression of the infection by the type 1 human immunodeficiency virus in a population of seropositive subjects in Madrid]. Med Clin (Barc) (1996) 1.38
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[35S]-methionine labelled polypeptides from HELA cells. Coordinates and percentage of some major polypeptides. Cell Biol Int Rep (1981) 1.34
B cells lacking RelB are defective in proliferative responses, but undergo normal B cell maturation to Ig secretion and Ig class switching. J Exp Med (1996) 1.34
Role of nuclear material in the early cell cycle of Xenopus embryos. Cell (1988) 1.34
Developmental expression of the mouse c-rel proto-oncogene in hematopoietic organs. Development (1994) 1.34
Expression of the chemokine N51/KC in the thymus and epidermis of transgenic mice results in marked infiltration of a single class of inflammatory cells. J Exp Med (1994) 1.33
Antigen-induced eosinophilic lung inflammation develops in mice deficient in chemokine eotaxin. Blood (1998) 1.33
p50-NF-kappaB complexes partially compensate for the absence of RelB: severely increased pathology in p50(-/-)relB(-/-) double-knockout mice. J Exp Med (1997) 1.32
Tissue-specific expression of c-jun and junB during organogenesis in the mouse. Development (1989) 1.29
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Structure and mapping of the fosB gene. FosB downregulates the activity of the fosB promoter. Nucleic Acids Res (1992) 1.24
Constitutive expression of Bc1-3 in thymocytes increases the DNA binding of NF-kappaB1 (p50) homodimers in vivo. Mol Cell Biol (1996) 1.24
Gene expression in normal and virally transformed mouse 3T3b and hamster BHK21 cells. Exp Cell Res (1980) 1.24
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The NF-kappa B family member RelB is required for innate and adaptive immunity to Toxoplasma gondii. J Immunol (1999) 1.22
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Apoptosis of nur77/N10-transgenic thymocytes involves the Fas/Fas ligand pathway. Proc Natl Acad Sci U S A (1996) 1.22