Published in J Pharmacol Exp Ther on October 01, 1994
Failure of ductus arteriosus closure and remodeling in neonatal mice deficient in cyclooxygenase-1 and cyclooxygenase-2. Proc Natl Acad Sci U S A (2001) 1.58
EP1- and FP-mediated cross-desensitization of the alpha (alpha) and beta (beta) isoforms of the human thromboxane A2 receptor. Br J Pharmacol (2004) 1.50
Prostanoid receptor antagonists: development strategies and therapeutic applications. Br J Pharmacol (2009) 1.31
Chronic activation of the prostaglandin receptor EP4 promotes hyaluronan-mediated neointimal formation in the ductus arteriosus. J Clin Invest (2006) 1.29
Prostanoid receptors involved in the relaxation of human bronchial preparations. Br J Pharmacol (1999) 1.01
Pharmacological studies on prostanoid receptors in the rabbit isolated saphenous vein: a comparison with the rabbit isolated ear artery. Br J Pharmacol (1996) 1.01
Characterization of the prostanoid receptors mediating constriction and relaxation of human isolated uterine artery. Br J Pharmacol (1995) 0.99
Molecular mechanisms regulating the vascular prostacyclin pathways and their adaptation during pregnancy and in the newborn. Pharmacol Rev (2012) 0.97
Vasorelaxation induced by prostaglandin E2 in human pulmonary vein: role of the EP4 receptor subtype. Br J Pharmacol (2008) 0.94
Expression of prostanoid receptors in human ductus arteriosus. Br J Pharmacol (2003) 0.83
An EP receptor with a novel pharmacological profile in the T-cell line Jurkat. Br J Pharmacol (1995) 0.83
Developmental changes in the effects of prostaglandin E2 in the chicken ductus arteriosus. J Comp Physiol B (2008) 0.79
Guidelines for reporting experiments involving animals: the ARRIVE guidelines. Br J Pharmacol (2010) 13.76
Evidence for more than one type of post-junctional alpha-adrenoceptor. Biochem Pharmacol (1982) 3.62
Glycogen storage disease in adults. Ann Intern Med (1994) 3.58
Adrenergic and 'non-adrenergic' components in the contractile response of the vas deferens to a single indirect stimulus. J Physiol (1978) 3.39
Enzymes of glycerolipid synthesis in eukaryotes. Annu Rev Biochem (1980) 3.06
Immunocytochemical localization of phytochrome. Proc Natl Acad Sci U S A (1971) 2.81
Comparison of the actions of U-46619, a prostaglandin H2-analogue, with those of prostaglandin H2 and thromboxane A2 on some isolated smooth muscle preparations. Br J Pharmacol (1981) 2.79
Studies on the characterisation of prostanoid receptors: a proposed classification. Prostaglandins (1982) 2.73
The response of the cat anococcygeus muscle to nerve or drug stimulation and a comparison with the rat anococcygeus. Br J Pharmacol (1974) 2.67
A new preparation of the isolated intact trachea of the guinea-pig. J Pharm Pharmacol (1970) 2.58
The spinal origin of the motor and inhibitory innervation of the rat anococcygeus muscles. J Physiol (1973) 2.58
The Concise Guide to PHARMACOLOGY 2013/14: overview. Br J Pharmacol (2013) 2.48
AMP-activated kinase reciprocally regulates triacylglycerol synthesis and fatty acid oxidation in liver and muscle: evidence that sn-glycerol-3-phosphate acyltransferase is a novel target. Biochem J (1999) 2.46
Salmeterol, a novel, long-acting beta 2-adrenoceptor agonist: characterization of pharmacological activity in vitro and in vivo. Br J Pharmacol (1991) 2.41
A comparison of pre- and post-junctional potencies of several alpha-adrenoceptor agonists in the cardiovascular system and anococcygeus muscle of the rat. Evidence for two types of post-junctional alpha-adrenoceptor. Naunyn Schmiedebergs Arch Pharmacol (1980) 2.27
An immunochemical characterization of the phytochrome destruction reaction. Biochim Biophys Acta (1974) 2.20
Analysis of amino acid motifs diagnostic for the sn-glycerol-3-phosphate acyltransferase reaction. Biochemistry (1999) 2.04
Reversible redistribution of phytochrome within the cell upon conversion to its physiologically active form. Proc Natl Acad Sci U S A (1975) 2.01
An analysis of the anatomical basis for the mechanical response to motor nerve stimulation of the rat vas deferens. J Physiol (1977) 1.97
A non-adrenergic inhibitory nervous pathway in guinea-pig trachea. Br J Pharmacol (1974) 1.97
The inducement of tone and its inhibition in isolated tracheal muscle. J Pharm Pharmacol (1971) 1.95
Selective changes in microsomal enzymes of triacylglycerol phosphatidylcholine, and phosphatidylethanolamine biosynthesis during differentiation of 3T3-L1 preadipocytes. J Biol Chem (1978) 1.86
The effect of pithing and of nerve stimulation on the depletion of noradrenaline by reserpine in the rat anococcygeus muscle and vas deferens. Br J Pharmacol (1974) 1.85
The effects of lysergic acid diethylamide on the response to field stimulation of the rat vas deferens and the rat and cat anococcygeus muscles. Br J Pharmacol (1975) 1.83
Separation of adrenergic and non-adrenergic contractions to field stimulation in the rat vas deferens. Br J Pharmacol (1983) 1.79
Effects of some purine derivatives on the guinea-pig trachea and their interaction with drugs that block adenosine uptake. Br J Pharmacol (1976) 1.77
Effects of nifedipine on electrical and mechanical responses of rat and guinea pig vas deferens. Nature (1981) 1.69
Acyl-CoA synthetase isoforms 1, 4, and 5 are present in different subcellular membranes in rat liver and can be inhibited independently. J Biol Chem (2001) 1.64
Expression and characterization of recombinant rat Acyl-CoA synthetases 1, 4, and 5. Selective inhibition by triacsin C and thiazolidinediones. J Biol Chem (2001) 1.64
AH23848: a thromboxane receptor-blocking drug that can clarify the pathophysiologic role of thromboxane A2. Circulation (1985) 1.63
Leptin directly alters lipid partitioning in skeletal muscle. Diabetes (1997) 1.57
Acylglycerol recycling from triacylglycerol to phospholipid, not lipase activity, is defective in neutral lipid storage disease fibroblasts. J Biol Chem (1996) 1.48
Electron microscopic localization of phytochrome in plants using an indirect antibody-labeling method. J Histochem Cytochem (1974) 1.47
Angiotensin II causes vascular hypertrophy in part by a non-pressor mechanism. Hypertension (1991) 1.46
Renal disease in type I glycogen storage disease. N Engl J Med (1988) 1.45
alpha 1- and alpha 2-Adrenoceptor-mediated pressor and chronotropic effects in the rat and rabbit. J Cardiovasc Pharmacol (1982) 1.44
The effects of alpha-adrenoceptor agonists and antagonists on responses of transmurally stimulated prostatic and epididymal portions of the isolated vas deferens of the rat. Br J Pharmacol (1979) 1.42
"Selectivity" and "specificity": what do they mean? Gen Pharmacol (1993) 1.40
Inhibition of natural anti-inflammatory mechanism by beta 2-agonists. Lancet (1991) 1.40
Triacsin C blocks de novo synthesis of glycerolipids and cholesterol esters but not recycling of fatty acid into phospholipid: evidence for functionally separate pools of acyl-CoA. Biochem J (1997) 1.39
Further sub-classification of alpha-adrenoceptors in the cardiovascular system, vas deferens and anococcygeus of the rat [proceedings]. Br J Pharmacol (1979) 1.39
Lipid topogenesis. J Lipid Res (1981) 1.36
Potentiation of cardiac sympathetic nerve responses in vivo by pancuronium bromide [proceedings]. Br J Pharmacol (1977) 1.31
The distribution of adrenoceptors and other drug receptors between the two ends of the rat vas deferens as revealed by selective agonists and antagonists. Br J Pharmacol (1980) 1.30
U-46619, a selective thromboxane A2-like agonist? [proceedings]. Br J Pharmacol (1980) 1.28
Neutral lipid storage disease with fatty liver and cholestasis. J Pediatr Gastroenterol Nutr (1997) 1.27
Mitochondrial glycerol phosphate acyltransferase directs the incorporation of exogenous fatty acids into triacylglycerol. J Biol Chem (2001) 1.26
Characterisation of the prostanoid receptors mediating contraction of guinea-pig isolated trachea. Prostaglandins (1985) 1.26
Effects of ketamine on the peripheral autonomic nervous system of the rat. Br J Pharmacol (1976) 1.25
An examination of factors influencing adrenergic transmission in the pithed rat, with special reference to noradrenaline uptake mechanisms and post-junctional alpha-adrenoceptors. Naunyn Schmiedebergs Arch Pharmacol (1980) 1.25
Contractile and relaxant actions of prostaglandins on guinea-pig isolated trachea. Br J Pharmacol (1980) 1.25
An analysis of some factors influencing alpha-adrenoceptor feed-back at the sympathetic junction in the rat heart. Br J Pharmacol (1979) 1.24
The effects of intravenous anaesthetics on the cardiovascular system of the rabbit. Br J Pharmacol (1977) 1.24
Alpha 2-adrenoceptor subtypes and imidazoline-like binding sites in the rat brain. Br J Pharmacol (1990) 1.23
Immunoblot analyses of glycogen debranching enzyme in different subtypes of glycogen storage disease type III. J Pediatr (1990) 1.22
Neutral lipid storage disease: a genetic disorder with abnormalities in the regulation of phospholipid metabolism. J Lipid Res (1998) 1.22
An examination of the postjunctional alpha-adrenoceptor subtypes for (-)-noradrenaline in several isolated blood vessels from the rabbit. Br J Pharmacol (1988) 1.22
Characterization of the PGE receptor subtype mediating inhibition of superoxide production in human neutrophils. Br J Pharmacol (1995) 1.19
Evidence for prazosin-resistant, rauwolscine-sensitive alpha-adrenoceptors mediating contractions in the isolated vascular bed of the rat tail. Br J Pharmacol (1989) 1.19
Analysis of the alpha-adrenoceptor-mediated, and other, components in the sympathetic vasopressor responses of the pithed rat. Br J Pharmacol (1985) 1.19
Phase I and pharmacokinetic study of LM985 (flavone acetic acid ester). Cancer Res (1986) 1.19
Sustained activation of a G protein-coupled receptor via "anchored" agonist binding. Molecular localization of the salmeterol exosite within the 2-adrenergic receptor. J Biol Chem (1996) 1.18
Fluorescent ligand binding reveals heterogeneous distribution of adrenoceptors and 'cannabinoid-like' receptors in small arteries. Br J Pharmacol (2010) 1.16
Sympathomimetic effects of pancuronium bromide on the cardiovascular system of the pithed rat: a comparison with the effects of drugs blocking the neuronal uptake of noradrenaline. Br J Pharmacol (1978) 1.16
An attempt at selective protection from phenoxybenzamine of postjunctional alpha-adrenoceptor subtypes mediating contractions to noradrenaline in the rabbit isolated saphenous vein. Br J Pharmacol (1988) 1.16
Blockade of vasopressor and vas deferens responses by alpha,beta-methylene ATP in the pithed rat. Br J Pharmacol (1988) 1.14
Isolation of the 'non-adrenergic' motor nerve response in rat vas deferens by elimination of the adrenergic motor component [proceedings]. J Physiol (1978) 1.14
Regulation of mitochondrial sn-glycerol-3-phosphate acyltransferase activity: response to feeding status is unique in various rat tissues and is discordant with protein expression. Arch Biochem Biophys (2001) 1.14
Dynamic interplay of TFIIA, TBP and TATA DNA. J Mol Biol (1997) 1.13
Immunolocalization of the secretory isoform of Na-K-Cl cotransporter in rat renal intercalated cells. J Am Soc Nephrol (1996) 1.13
The pharmacology of salmeterol. Life Sci (1993) 1.13
Investigations into factors determining the duration of action of the beta 2-adrenoceptor agonist, salmeterol. Br J Pharmacol (1993) 1.12
Quantitative imaging in live human cells reveals intracellular alpha(1)-adrenoceptor ligand-binding sites. J Pharmacol Exp Ther (2000) 1.12
Measurement of cytochrome P450 gene induction in human hepatocytes using quantitative real-time reverse transcriptase-polymerase chain reaction. Drug Metab Dispos (2000) 1.11
Diacylglycerol acyltransferase and monoacylglycerol acyltransferase from liver and intestine. Methods Enzymol (1992) 1.11
Independent effects of patch size and structural complexity on diversity of benthic macroinvertebrates. Ecology (2010) 1.10
The influence of blood gases on alpha 1- and alpha 2- adrenoceptor-mediated pressor responses in the pithed rat. Br J Pharmacol (1985) 1.09
Studies on the characterization of prostanoid receptors. Adv Prostaglandin Thromboxane Leukot Res (1983) 1.07
Rat sn-glycerol-3-phosphate acyltransferase: molecular cloning and characterization of the cDNA and expressed protein. Biochim Biophys Acta (1999) 1.06
Alpha1A/B-knockout mice explain the native alpha1D-adrenoceptor's role in vasoconstriction and show that its location is independent of the other alpha1-subtypes. Br J Pharmacol (2009) 1.05
Expression of functional postjunctional alpha 2-adrenoceptors in rabbit isolated distal saphenous artery--a permissive role for angiotensin II? Br J Pharmacol (1989) 1.04
Cellular aspects of vascular remodeling in hypertension revealed by confocal microscopy. Hypertension (1997) 1.04
Influence of blood gases, Ca2+-entry blockade and angiotensin converting enzyme inhibition on pressor responses to alpha-adrenoceptor agonists: evidence in vivo for subtypes of response independent of receptor subtype? Clin Sci (Lond) (1985) 1.03
The influence of the initial stretch and the agonist-induced tone on the effect of basal and stimulated release of EDRF. Br J Pharmacol (1990) 1.03
Myopathy and growth failure in debrancher enzyme deficiency: improvement with high-protein nocturnal enteral therapy. J Pediatr (1984) 1.03
Are there more than two types of alpha-adrenoceptors involved in physiological responses? Exp Physiol (1991) 1.03
Mitochondrial glycerol phosphate acyltransferase contains two transmembrane domains with the active site in the N-terminal domain facing the cytosol. J Biol Chem (2001) 1.03
Further evidence for adrenergic transmission in the human vas deferens. J Physiol (1977) 1.02
Hypotension, autonomic failure, and cardiac hypertrophy in transgenic mice overexpressing the alpha 1B-adrenergic receptor. J Biol Chem (2001) 1.02
Release of [3H]-noradrenaline by field stimulation and by drugs from the anococcygeus muscle (proceedings). Br J Pharmacol (1977) 1.02
The factors influencing the time course of drug action at alpha-adrenoceptors: an investigation of the effects of clonidine in the pithed rat. Br J Pharmacol (1980) 1.01
Alpha-adrenoceptor antagonism by apoyohimbine and some observations on the pharmacology of alpha-adrenoceptors in the rat anococcygeus and vas deferens. Br J Pharmacol (1984) 1.01
The cat isolated trachea, a useful preparation for the study of the smooth muscle relaxant action of prostaglandins [proceedings]. Br J Pharmacol (1979) 1.01
The use of fluorescent nuclear dyes for the study of blood vessel structure and function: novel applications of existing techniques. J Vasc Res (1992) 1.01
Improvement of muscle function in acid maltase deficiency by high-protein therapy. Neurology (1983) 1.00
Selective retention of essential fatty acids: the role of hepatic monoacylglycerol acyltransferase. Am J Physiol (1993) 0.99
Characterization of the prostanoid receptors mediating constriction and relaxation of human isolated uterine artery. Br J Pharmacol (1995) 0.99
Evidence that the population of postjunctional-adrenoceptors mediating contraction of smooth muscle in the rabbit isolated ear vein is predominantly alpha 2. Br J Pharmacol (1988) 0.99