Published in Antimicrob Agents Chemother on August 01, 1994
Lead optimization of 3-carboxyl-4(1H)-quinolones to deliver orally bioavailable antimalarials. J Med Chem (2012) 0.88
Synthesis and structure-activity relationships of antimalarial 4-oxo-3-carboxyl quinolones. Bioorg Med Chem (2010) 0.87
Febrifugine analogue compounds: synthesis and antimalarial evaluation. Bioorg Med Chem (2011) 0.77
Quantitative assessment of antimalarial activity in vitro by a semiautomated microdilution technique. Antimicrob Agents Chemother (1979) 17.49
Antimalarial drug susceptibility testing of Plasmodium falciparum in Thailand using a microdilution radioisotope method. Am J Trop Med Hyg (1985) 3.54
Antimalarial activities of various 4-quinolonemethanols with special attention to WR-142,490 (mefloquine). Antimicrob Agents Chemother (1978) 2.52
Randomised trial of artesunate and mefloquine alone and in sequence for acute uncomplicated falciparum malaria. Lancet (1992) 2.14
Relations among antimalarial drugs: results of studies with cycloguanil-, sulfone-, or chloroquine-resistant Plasmodium berghei in mice. Am J Trop Med Hyg (1967) 1.12
Quinine with tetracycline for the treatment of drug-resistant falciparum malaria in Thailand. Am J Trop Med Hyg (1992) 1.11
Comparison of Plasmodium falciparum infections in Panamanian and Colombian owl monkeys. Am J Trop Med Hyg (1985) 1.05
Antimalarial properties of floxacrine, a dihydroacridinedione derivative. Antimicrob Agents Chemother (1979) 0.98
The development of a "high volume tissue schizonticidal drug screen" based upon mortality of mice inoculated with sporozoites of Plasmodium berghei. Am J Trop Med Hyg (1979) 0.97
In vitro and clinical correlates of mefloquine resistance of Plasmodium falciparum in eastern Thailand. Am J Trop Med Hyg (1991) 0.93
The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. Cholesterol and Recurrent Events Trial investigators. N Engl J Med (1996) 23.76
Partnership synergy: a practical framework for studying and strengthening the collaborative advantage. Milbank Q (2001) 7.25
Body mass index, serum sex hormones, and breast cancer risk in postmenopausal women. J Natl Cancer Inst (2003) 6.20
A testing time for doctors: counselling patients before an HIV test. BMJ (1991) 5.14
The Greater Cincinnati/Northern Kentucky Stroke Study: preliminary first-ever and total incidence rates of stroke among blacks. Stroke (1998) 4.93
Public perception of stroke warning signs and knowledge of potential risk factors. JAMA (1998) 4.21
Calcium antagonism and calcium entry blockade. Pharmacol Rev (1986) 4.15
The Montgomery-Asberg Depression Scale: reliability and validity. Acta Psychiatr Scand (1986) 4.12
Evaluation of the E test, a novel method of quantifying antimicrobial activity. J Antimicrob Chemother (1991) 4.06
A controlled trial of a formalin-inactivated hepatitis A vaccine in healthy children. N Engl J Med (1992) 4.05
The respiratory burst of phagocytic cells is associated with a rise in vacuolar pH. Nature (1981) 4.01
Randomised trial of high-dose isosorbide dinitrate plus low-dose furosemide versus high-dose furosemide plus low-dose isosorbide dinitrate in severe pulmonary oedema. Lancet (1998) 3.85
Detection of Legionella with polymerase chain reaction and gene probe methods. Mol Cell Probes (1990) 3.83
Insertion mutations in the dam gene of Escherichia coli K-12. Mol Gen Genet (1983) 3.61
The risk of subarachnoid and intracerebral hemorrhages in blacks as compared with whites. N Engl J Med (1992) 3.56
Interaction between the origin recognition complex and the replication licensing system in Xenopus. Cell (1996) 3.45
Quick medical reference (QMR) for diagnostic assistance. MD Comput (1986) 3.43
Improved data, methods and tools for the 2007 HIV and AIDS estimates and projections. Sex Transm Infect (2008) 3.38
Research needs for the risk assessment of health and environmental effects of endocrine disruptors: a report of the U.S. EPA-sponsored workshop. Environ Health Perspect (1996) 3.34
Recombinant immune interferon increases immunoglobulin G Fc receptors on cultured human mononuclear phagocytes. J Clin Invest (1983) 3.32
Clinical problem-solving. Through thick and thin. N Engl J Med (1998) 3.27
Influence of body temperature on the development of fatigue during prolonged exercise in the heat. J Appl Physiol (1985) (1999) 3.24
Firing modes of midbrain dopamine cells in the freely moving rat. Neuroscience (2002) 3.22
Model-based drug development. Clin Pharmacol Ther (2007) 3.04
A deletion map of the human Y chromosome based on DNA hybridization. Am J Hum Genet (1986) 3.03
Digital dynamic telepathology--the Virtual Microscope. Proc AMIA Symp (1998) 3.01
The Virtual Microscope. Proc AMIA Annu Fall Symp (1997) 3.00
Database of patients' experiences (DIPEx): a multi-media approach to sharing experiences and information. Lancet (2000) 2.97
Mental health in complex emergencies. Lancet (2004) 2.97
Guidelines for radiologically guided lung biopsy. Thorax (2003) 2.91
The treatment of tuberculosis in HIV-infected persons. AIDS (1999) 2.86
STACK: Sequence Tag Alignment and Consensus Knowledgebase. Nucleic Acids Res (2001) 2.85
Innate and acquired humoral immunities to influenza virus are mediated by distinct arms of the immune system. Proc Natl Acad Sci U S A (1999) 2.63
Topological restriction of SNARE-dependent membrane fusion. Nature (2000) 2.58
PDEF, a novel prostate epithelium-specific ets transcription factor, interacts with the androgen receptor and activates prostate-specific antigen gene expression. J Biol Chem (2000) 2.57
Susceptibility of highly pathogenic A(H5N1) avian influenza viruses to the neuraminidase inhibitors and adamantanes. Antiviral Res (2006) 2.43
Multiplex PCR amplification and immobilized capture probes for detection of bacterial pathogens and indicators in water. Mol Cell Probes (1990) 2.28
Low-cost high-resolution fast spin-echo MR of acoustic schwannoma: an alternative to enhanced conventional spin-echo MR? AJNR Am J Neuroradiol (1996) 2.24
Intracerebral hemorrhage more than twice as common as subarachnoid hemorrhage. J Neurosurg (1993) 2.22
General practitioner-hospital communications: a review of discharge summaries. J Qual Clin Pract (2001) 2.21
The parkinsonian toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): a technical review of its utility and safety. J Neurochem (2001) 2.18
Evidence for dopamine receptor pruning between adolescence and adulthood in striatum but not nucleus accumbens. Brain Res Dev Brain Res (1995) 2.11
Perfusion of the spleen with blood containing prostaglandin E1: transmitter liberation and uptake. Proc R Soc Lond B Biol Sci (1969) 2.11
Transmission of tuberculosis in British centre for patients infected with HIV. BMJ (1994) 2.11
Counselling patients before an HIV test. BMJ (1991) 2.08
A novel human protein serine/threonine phosphatase, which possesses four tetratricopeptide repeat motifs and localizes to the nucleus. EMBO J (1994) 1.98
What does fluorodeoxyglucose PET imaging add to a clinical diagnosis of dementia? Neurology (2007) 1.95
Adverse effects and drug interactions of medications commonly used in the treatment of adult HIV positive patients: Part 2. Genitourin Med (1997) 1.94
Psychotropic drug use in Sydney nursing homes. Med J Aust (1995) 1.94
The HAP3 regulatory locus of Saccharomyces cerevisiae encodes divergent overlapping transcripts. Mol Cell Biol (1988) 1.87
Lipases at interfaces: a review. Adv Colloid Interface Sci (2008) 1.86
Photon blockade in an optical cavity with one trapped atom. Nature (2005) 1.84
An immunodeficiency characterized by defective signal transduction in T lymphocytes. N Engl J Med (1989) 1.79
Optimizing Shake-and-Bake for proteins. Acta Crystallogr D Biol Crystallogr (1999) 1.78
HIV seroprevalence in a London same-day testing clinic. AIDS (1994) 1.78
Apoptosis and the cell cycle. Curr Opin Cell Biol (1995) 1.76
Rat models of hypertension, cardiac hypertrophy and failure. Cardiovasc Res (1998) 1.76
The influence of volumetric tumor doubling time, DNA ploidy, and histologic grade on the survival of patients with intracranial astrocytomas. AJNR Am J Neuroradiol (1995) 1.74
Differential effects of hydrogen peroxide on indices of endothelial cell function. J Exp Med (1984) 1.72
Coexistent Mahaim and Kent accessory connections: diagnostic and therapeutic implications. J Am Coll Cardiol (1987) 1.72
Immunologic phenotype in 30 patients with diffuse large-cell lymphoma. N Engl J Med (1980) 1.68
The cervical aortic arch. Am J Roentgenol Radium Ther Nucl Med (1975) 1.68
Relation of prediagnostic serum estrogen and androgen levels to breast cancer risk. Cancer Epidemiol Biomarkers Prev (1996) 1.67
Neurotoxicity in animals due to arteether and artemether. Trans R Soc Trop Med Hyg (1994) 1.67
An entrapped epidural catheter in a postpartum patient. Reg Anesth Pain Med (1999) 1.63
Expressed sequences from conidial, mycelial, and sexual stages of Neurospora crassa. Fungal Genet Biol (1997) 1.62
How has the 'two-week wait' rule affected the presentation of colorectal cancer? Colorectal Dis (2005) 1.62
Influences on clinical practice: the case of glue ear. Qual Health Care (1999) 1.62
Effects of dopamine-like drugs on rat striatal adenyl cyclase have implications for CNS dopamine receptor topography. Nature (1974) 1.62
Inhibition of Cuticular Lipid Biosynthesis in Pisum sativum by Thiocarbamates. Plant Physiol (1974) 1.61
Bulbar amyotrophic lateral sclerosis: patterns of progression and clinical management. Head Neck (1989) 1.60
Long-term attendance at a family practice teaching unit. Qualitative study of patients' views. Can Fam Physician (1997) 1.60
Quantifying non-compliance in patients receiving digoxin--a pharmacokinetic approach. S Afr Med J (1991) 1.59
Anticentromere antibody as a predictor of digital ischemic loss in patients with systemic sclerosis. Arthritis Rheum (1992) 1.59
Paromomycin is effective as prophylaxis for cryptosporidiosis in dairy calves. J Parasitol (1993) 1.58
Is 'watchful waiting' a real choice for men with prostate cancer? A qualitative study. BJU Int (2002) 1.57
Intermittent androgen suppression with leuprolide and flutamide for prostate cancer: a pilot study. Urology (1996) 1.57
Height, mass and skeletal maturity of elite Portuguese soccer players aged 11-16 years. J Sports Sci (2000) 1.57
Metalloproteinase-mediated regulation of L-selectin levels on leucocytes. J Biol Chem (1996) 1.55
Effects of isolation and culture on prostaglandin synthesis by porcine aortic endothelial and smooth muscle cells. J Cell Physiol (1982) 1.55
Frozen human serum reference material for standardization of sodium and potassium measurements in serum or plasma by ion-selective electrode analyzers. Clin Chem (1992) 1.55
High resolution computed tomography of Pneumocystis carinii pneumonia in AIDS. Clin Radiol (1990) 1.54
Successful treatment of drug-resistant cutaneous leishmaniasis in humans by use of imiquimod, an immunomodulator. Clin Infect Dis (2001) 1.53
TAL2, a helix-loop-helix gene activated by the (7;9)(q34;q32) translocation in human T-cell leukemia. Proc Natl Acad Sci U S A (1991) 1.53
Notes: a suitable case for audit. Postgrad Med J (1993) 1.53
Repeat HIV testing: high-risk behaviour or risk reduction strategy? AIDS (2000) 1.52
Abdominal compartment syndrome in patients with isolated extraperitoneal injuries. J Trauma (2000) 1.52
Medicinal plants in the fight against leishmaniasis. Parasitol Today (1994) 1.51
Behavioral changes correlated with brain-stem auditory evoked responses in term infants with moderate hyperbilirubinemia. J Pediatr (1990) 1.50
Helicobacter pylori eradication does not exacerbate reflux symptoms in gastroesophageal reflux disease. Gastroenterology (2001) 1.50
Nucleotide sequence of the avian influenza A/Mallard/NY/6750/78 virus polymerase genes. Virus Res (1989) 1.49
Fatal neurotoxicity of arteether and artemether. Am J Trop Med Hyg (1994) 1.49
First-time-in-humans safety and pharmacokinetics of WR 238605, a new antimalarial. Am J Trop Med Hyg (1998) 1.48
Mechanisms of T cell activation by the calcium ionophore ionomycin. J Immunol (1989) 1.48
Fas (CD95) participates in peripheral T cell deletion and associated apoptosis in vivo. Int Immunol (1995) 1.47
The role of lasers in urology. Br J Urol (1994) 1.46
Preliminary evidence for abnormal cortical development in physically and sexually abused children using EEG coherence and MRI. Ann N Y Acad Sci (1997) 1.46