Published in Cell on September 09, 1994
Maltose/maltodextrin system of Escherichia coli: transport, metabolism, and regulation. Microbiol Mol Biol Rev (1998) 4.45
Signal peptide-dependent protein transport in Bacillus subtilis: a genome-based survey of the secretome. Microbiol Mol Biol Rev (2000) 3.81
Distinct catalytic roles of the SecYE, SecG and SecDFyajC subunits of preprotein translocase holoenzyme. EMBO J (1997) 2.60
Interaction between the autokinase EpsE and EpsL in the cytoplasmic membrane is required for extracellular secretion in Vibrio cholerae. EMBO J (1995) 2.24
The SecDFyajC domain of preprotein translocase controls preprotein movement by regulating SecA membrane cycling. EMBO J (1997) 1.74
SecYEG assembles into a tetramer to form the active protein translocation channel. EMBO J (2000) 1.74
Mapping an interface of SecY (PrlA) and SecE (PrlG) by using synthetic phenotypes and in vivo cross-linking. J Bacteriol (1999) 1.52
The VirB4 ATPase of Agrobacterium tumefaciens is a cytoplasmic membrane protein exposed at the periplasmic surface. J Bacteriol (1997) 1.50
Human peroxisomal targeting signal-1 receptor restores peroxisomal protein import in cells from patients with fatal peroxisomal disorders. J Cell Biol (1995) 1.45
SecY and SecA interact to allow SecA insertion and protein translocation across the Escherichia coli plasma membrane. EMBO J (1997) 1.43
Interactions of VirB9, -10, and -11 with the membrane fraction of Agrobacterium tumefaciens: solubility studies provide evidence for tight associations. J Bacteriol (1995) 1.39
The molecular chaperone SecB is released from the carboxy-terminus of SecA during initiation of precursor protein translocation. EMBO J (1997) 1.38
Cytoplasmic ATP hydrolysis powers transport of lipopolysaccharide across the periplasm in E. coli. Science (2012) 1.37
Non-bilayer lipids are required for efficient protein transport across the plasma membrane of Escherichia coli. EMBO J (1995) 1.36
The bacterial Sec-translocase: structure and mechanism. Philos Trans R Soc Lond B Biol Sci (2012) 1.22
Both an N-terminal 65-kDa domain and a C-terminal 30-kDa domain of SecA cycle into the membrane at SecYEG during translocation. Proc Natl Acad Sci U S A (1997) 1.20
Evaluating the oligomeric state of SecYEG in preprotein translocase. EMBO J (2000) 1.18
Identification of the fliI and fliJ components of the Caulobacter flagellar type III protein secretion system. J Bacteriol (1997) 1.17
Membrane deinsertion of SecA underlying proton motive force-dependent stimulation of protein translocation. EMBO J (1999) 1.12
Targeting of signal sequenceless proteins for export in Escherichia coli with altered protein translocase. EMBO J (1996) 1.09
A new genetic selection identifies essential residues in SecG, a component of the Escherichia coli protein export machinery. EMBO J (1995) 1.07
Identification and characterization of protease-resistant SecA fragments: secA has two membrane-integral forms. J Bacteriol (1998) 1.06
Lipopolysaccharide transport and assembly at the outer membrane: the PEZ model. Nat Rev Microbiol (2016) 1.05
Suppression of signal sequence defects and azide resistance in Escherichia coli commonly result from the same mutations in secA. J Bacteriol (1995) 1.04
Role of lipids in the translocation of proteins across membranes. Biochem J (2000) 1.04
Mapping of the SecA·SecY and SecA·SecG interfaces by site-directed in vivo photocross-linking. J Biol Chem (2011) 1.02
In vivo cross-linking of the SecA and SecY subunits of the Escherichia coli preprotein translocase. J Bacteriol (1997) 0.97
In vitro disassembly and reassembly of an ABC transporter, the histidine permease. Proc Natl Acad Sci U S A (1998) 0.95
The MalK protein of the ATP-binding cassette transporter for maltose of Escherichia coli is accessible to protease digestion from the periplasmic side of the membrane. J Bacteriol (1995) 0.94
Sites of interaction between SecA and the chaperone SecB, two proteins involved in export. Protein Sci (2004) 0.94
SecA proteins of Bacillus subtilis and Escherichia coli possess homologous amino-terminal ATP-binding domains regulating integration into the plasma membrane. J Bacteriol (1995) 0.90
Purification, crystallization and preliminary X-ray diffraction of SecDF, a translocon-associated membrane protein, from Thermus thermophilus. Acta Crystallogr Sect F Struct Biol Cryst Commun (2006) 0.90
SecA alone can promote protein translocation and ion channel activity: SecYEG increases efficiency and signal peptide specificity. J Biol Chem (2011) 0.88
Bacterial Sec protein transport is rate-limited by precursor length: a single turnover study. Mol Biol Cell (2009) 0.88
Stage- and ribosome-specific alterations in nascent chain-Sec61p interactions accompany translocation across the ER membrane. J Cell Biol (1995) 0.88
Comparative characterization of SecA from the alpha-subclass purple bacterium Rhodobacter capsulatus and Escherichia coli reveals differences in membrane and precursor specificity. J Bacteriol (1997) 0.87
Differential translocation of protein precursors across SecY-deficient membranes of Escherichia coli: SecY is not obligatorily required for translocation of certain secretory proteins in vitro. J Bacteriol (1997) 0.86
Site-specific proteolysis of the Escherichia coli SecA protein in vivo. J Bacteriol (1996) 0.85
A mutation in secY that causes enhanced SecA insertion and impaired late functions in protein translocation. J Bacteriol (2000) 0.83
Identification of a sequence motif that confers SecB dependence on a SecB-independent secretory protein in vivo. J Bacteriol (1998) 0.82
Multiple SecA molecules drive protein translocation across a single translocon with SecG inversion. J Biol Chem (2011) 0.82
Competition between functional signal peptides demonstrates variation in affinity for the secretion pathway. J Bacteriol (1996) 0.82
Assembly of the translocase motor onto the preprotein-conducting channel. Mol Microbiol (2008) 0.82
A novel aerobic respiratory chain-linked NADH oxidase system in Zymomonas mobilis. J Bacteriol (1995) 0.79
Identification of a Role for an Azide-Sensitive Factor in the Thylakoid Transport of the 17-Kilodalton Subunit of the Photosynthetic Oxygen-Evolving Complex Plant Physiol (1998) 0.79
Determination of the Oligomeric State of SecYEG Protein Secretion Channel Complex Using in Vivo Photo- and Disulfide Cross-linking. J Biol Chem (2016) 0.78
Specificity of SecYEG for PhoA precursors and SecA homologs on SecA protein-conducting channels. Biochem Biophys Res Commun (2013) 0.78
Position-dependent effects of polylysine on Sec protein transport. J Biol Chem (2012) 0.78
Evolutionary evidence on suitability of SecD as a target for development of antibacterial agents against Staphylococcus aureus. Ecol Evol (2016) 0.75
Identifying predictors of high quality care in English general practice: observational study. BMJ (2001) 9.34
Protein secretion in Escherichia coli. Annu Rev Microbiol (1985) 6.74
Mutations that alter the signal sequence of alkaline phosphatase in Escherichia coli. J Bacteriol (1983) 6.27
Development and validation of a simple NAFLD clinical scoring system for identifying patients without advanced disease. Gut (2008) 3.88
PIP2 and PIP as determinants for ATP inhibition of KATP channels. Science (1998) 3.88
SecA protein hydrolyzes ATP and is an essential component of the protein translocation ATPase of Escherichia coli. EMBO J (1989) 3.33
SecA protein, a peripheral protein of the Escherichia coli plasma membrane, is essential for the functional binding and translocation of proOmpA. EMBO J (1989) 2.33
Two distinct ATP-binding domains are needed to promote protein export by Escherichia coli SecA ATPase. Mol Microbiol (1993) 2.18
Serum aminotransferase levels and platelet counts as predictors of degree of fibrosis in chronic hepatitis C virus infection. Am J Gastroenterol (2001) 2.04
Evaluation of innovations in nursing practice: report and discussion. Br J Nurs (2006) 1.89
Acquired cystic disease of the kidneys: a hazard of long-term intermittent maintenance haemodialysis. J Clin Pathol (1977) 1.83
Control of electrical activity in central neurons by modulating the gating of small conductance Ca2+-activated K+ channels. J Biol Chem (2000) 1.76
Reciprocal electromechanical properties of rat prestin: the motor molecule from rat outer hair cells. Proc Natl Acad Sci U S A (2001) 1.71
Brown-midrib maize (bm1)--a mutation affecting the cinnamyl alcohol dehydrogenase gene. Plant J (1998) 1.51
Topology of the integral membrane form of Escherichia coli SecA protein reveals multiple periplasmically exposed regions and modulation by ATP binding. J Biol Chem (1997) 1.43
Pleiotropic mutants affecting the secretory apparatus of Escherichia coli. Ann Microbiol (Paris) (1982) 1.40
A model for making outcomes research standard practice in clinical dietetics. J Am Diet Assoc (1998) 1.39
A modified procedure for fractionating histones. Biochem J (1972) 1.36
Multicenter seroepidemiologic study of the impact of cytomegalovirus infection on renal transplantation. Transplantation (1985) 1.29
Retardation of cochlear maturation and impaired hair cell function caused by deletion of all known thyroid hormone receptors. J Neurosci (2001) 1.28
Outcome in patients on continuous ambulatory peritoneal dialysis and haemodialysis: 4-year analysis of a prospective multicentre study. Lancet (1987) 1.23
Thyroid hormone receptor beta-dependent expression of a potassium conductance in inner hair cells at the onset of hearing. Proc Natl Acad Sci U S A (1998) 1.21
Falls in English and Welsh hospitals: a national observational study based on retrospective analysis of 12 months of patient safety incident reports. Qual Saf Health Care (2008) 1.20
SecA suppresses the temperature-sensitive SecY24 defect in protein translocation in Escherichia coli membrane vesicles. Proc Natl Acad Sci U S A (1988) 1.18
Dual regulation of Escherichia coli secA translation by distinct upstream elements. J Mol Biol (1997) 1.16
Identification of a region of interaction between Escherichia coli SecA and SecY proteins. J Biol Chem (1997) 1.11
Identification of a distinction between cytoplasmic histone synthesis and subsequent histone deposition within the nucleus. Biochemistry (1974) 1.07
An electrophoretic analysis of Drosophila histones. I. Isolation and identification. Exp Cell Res (1972) 1.06
An improved photographic system for polyacrylamide gels. Anal Biochem (1971) 1.05
Integration of SecA protein into the Escherichia coli inner membrane is regulated by its amino-terminal ATP-binding domain. Mol Microbiol (1996) 1.03
The course of the terminal phase in patients with amyotrophic lateral sclerosis. J Neurol (2001) 1.03
Distinct membrane binding properties of N- and C-terminal domains of Escherichia coli SecA ATPase. J Biol Chem (2000) 1.01
Tyr-326 plays a critical role in controlling SecA-preprotein interaction. Mol Microbiol (2000) 1.00
The primary pathway of protein export in E. coli. Cell (1991) 0.99
Revised translation start site for secM defines an atypical signal peptide that regulates Escherichia coli secA expression. J Bacteriol (2000) 0.98
Lipid and signal peptide-induced conformational changes within the C-domain of Escherichia coli SecA protein. Biochemistry (2001) 0.98
Molecular nature of F 1 histone phosphorylation in cultured hepatoma cells. Biochemistry (1972) 0.97
Training in palliative care. Br J Gen Pract (1998) 0.96
Constant electrophoretic mobility of the cysteine-containing histone in plants and animals. Biochim Biophys Acta (1970) 0.96
Carboxy-terminal region of Escherichia coli SecA ATPase is important to promote its protein translocation activity in vivo. Biochem Biophys Res Commun (1994) 0.95
Results from a new renal transplantation unit. Lancet (1979) 0.94
Analysis of the DNA-binding domain of the HSV-1 origin-binding protein. Virology (1994) 0.92
Competition between ribosome and SecA binding promotes Escherichia coli secA translational regulation. RNA (1995) 0.91
Asymmetric distribution of histone on DNA: a model for nucleohistone primary structure. Biochemistry (1974) 0.90
Nucleotide binding activity of SecA homodimer is conformationally regulated by temperature and altered by prlD and azi mutations. J Biol Chem (2000) 0.90
SecA proteins of Bacillus subtilis and Escherichia coli possess homologous amino-terminal ATP-binding domains regulating integration into the plasma membrane. J Bacteriol (1995) 0.90
ssaD1, a suppressor of secA51(Ts) that renders growth of Escherichia coli cold sensitive, is an early amber mutation in the transcription factor gene nusB. J Bacteriol (1994) 0.89
Terminal dehydration. Lancet (1984) 0.89
Turnover of deoxyribonucleic acid, histones, and lysine-rich histone phosphate in hepatoma tissue culture cells. Biochemistry (1972) 0.88
Sequencing, expression pattern and RFLP mapping of a senescence-enhanced cDNA from Zea mays with high homology to oryzain gamma and aleurain. Plant Mol Biol (1997) 0.88
Papillo-renal syndrome. An inherited association of optic disc dysplasia and renal disease. Report and review of the literature. Ophthalmic Paediatr Genet (1989) 0.88
End-of-life decisions in the United Kingdom involving medical practitioners and legalisation of euthanasia or physician-assisted suicide: survey of doctors' attitudes. Palliat Med (2009) 0.86
Multi-centre study on outcome of treatment in patients on continuous ambulatory peritoneal dialysis and haemodialysis. Nephrol Dial Transplant (1987) 0.85
Identification of elements on GeneX-secA RNA of Escherichia coli required for SecA binding and secA auto-regulation. J Mol Biol (1997) 0.85
Peroperative blood-transfusion improve cadaveric renal-allograft survival in non-transfused recipients. A prospective controlled clinical trial. Lancet (1980) 0.84
Developmental expression of the small-conductance Ca(2+)-activated potassium channel SK2 in the rat retina. Mol Cell Neurosci (2001) 0.84
Reef-coral proteins as visual, non-destructive reporters for plant transformation. Plant Cell Rep (2003) 0.84
Renal transplantation in the presence of a positive crossmatch. Transplant Proc (1978) 0.83
Infectious disease in Aboriginal infants and children in Western Australia. Med J Aust (1983) 0.82
Participation of community medical oncologists in clinical research trials. Prog Clin Biol Res (1986) 0.82
secG and temperature modulate expression of azide-resistant and signal sequence suppressor phenotypes of Escherichia coli secA mutants. J Bacteriol (1998) 0.82
Sequence and phylogenetic analysis of the Borrelia burgdorferi secA gene. Biochim Biophys Acta (1998) 0.79
The physician assistant in rural primary care practices: physician assistant activities and physician supervision at satellite and non-satellite practice sites. Med Care (1979) 0.78
Albumin dialysis in cirrhosis with superimposed acute liver injury: possible impact of albumin dialysis on hospitalization costs. Liver Int (2003) 0.78
Letter: B-cell alloantibodies and renal allografts. Lancet (1976) 0.78
Quality of life improvements in CAPD patients treated with subcutaneously administered erythropoietin for anemia. Perit Dial Int (1992) 0.78
The effect of a critical care outreach service and an early warning scoring system on respiratory rate recording on the general wards. Resuscitation (2007) 0.77
Exposure of free amino groups in the coupling factor of energized spinach chloroplasts. J Biol Chem (1976) 0.77
alpha-Glutathione S-transferase as a marker of hepatocellular damage in chronic hepatitis C virus infection. Am J Clin Pathol (1995) 0.77
Serum itraconazole concentrations and clinical responses in Candida-associated denture stomatitis patients treated with itraconazole solution and itraconazole capsules. J Antimicrob Chemother (2000) 0.76
What Iowa family physicians, residents and medical students think about physician's assistants. J Iowa Med Soc (1980) 0.76
Stereotactic fine needle aspiration biopsy (SFNB) of breast: preliminary results in Perth with the TRC mammotest machine. Cytological aspects. Pathology (1991) 0.76
Medical care in hospice day care. J Palliat Care (1993) 0.75
Experience of palliative medicine among trainees. Br J Gen Pract (1991) 0.75
Authors defend their study to develop tool to predict falls in elderly people. BMJ (1998) 0.75
Screening for neural tube defects. Med J Aust (1994) 0.75
Unusual association between non-Hodgkin's malignant lymphoma and a PNH-like defect in the red cell. Am J Med (1994) 0.75
A perspective on euthanasia. Br J Cancer (2006) 0.75
Euthanasia debate. Death from motor neurone disease can be peaceful. BMJ (1995) 0.75
The value of anticarcinoembryonic antigen, human milk factor globulin, and antikeratin antibodies in differentiating mesothelioma from lung carcinoma. Br J Ind Med (1991) 0.75
Carers of patients receiving palliative care. Specialized psychosocial care may be needed for carers. BMJ (1998) 0.75
Preparation and biokinetic evaluation of various halogenated iminodiacetic acid-type compounds labeled with technetium-99m for hepatobiliary scintigraphy in the baboon (Papio ursinus) model. Am J Physiol Imaging (1990) 0.75
Motivational factors for medical oncologists' participation in cancer treatment protocols. J Health Hum Resour Adm (1986) 0.75
Opioids in the last 72 hours of life. Palliat Med (1997) 0.75
Longitudinal plasma metanephrines preceding pheochromocytoma diagnosis: a retrospective case-control serum repository study. Eur J Endocrinol (2015) 0.75
Survey of physician's assistant programs in the United States. J Med Educ (1986) 0.75
Leukopenia and anergy as predictors of AIDS. JAMA (1986) 0.75
First, do no harm: healthcare workers with AIDS. N J Nurse (1990) 0.75
Competition among physicians. Avoiding anticompetitive activities. Consultant (1988) 0.75
A comparison between the performances of medical students and physician's assistant students in interdisciplinary courses. J Med Educ (1985) 0.75
Prediction and measurement of surfactant action upon human skin under realistic conditions. Int J Cosmet Sci (1984) 0.75
Advancing motor neurone disease (MND) J Palliat Care (2000) 0.75
Evidence that endogenous calcitonin protects against renal bone disease. Lancet (1976) 0.75
Oral thrush in hospice patients. Nurs Times (1987) 0.75
New experimental limits on strongly interacting massive particles at the TeV scale. Phys Rev Lett (2001) 0.75
Palliative drugs are not for shortening life. BMJ (1997) 0.75
Evidence for a relationship between plasma immunoreactive calcitonin and bone disease in chronic renal failure. Adv Exp Med Biol (1977) 0.75
The heavy hand of regulation. Adm Radiol (1987) 0.75
International collaboration in palliative care. Croat Med J (2001) 0.75