Published in Proc Natl Acad Sci U S A on November 01, 1975
Extracellular enzyme synthesis in the genus Bacillus. Bacteriol Rev (1977) 5.67
The cysteine switch: a principle of regulation of metalloproteinase activity with potential applicability to the entire matrix metalloproteinase gene family. Proc Natl Acad Sci U S A (1990) 4.46
Genes for alkaline protease and neutral protease from Bacillus amyloliquefaciens contain a large open reading frame between the regions coding for signal sequence and mature protein. J Bacteriol (1984) 3.45
Cloning of the neutral protease gene of Bacillus subtilis and the use of the cloned gene to create an in vitro-derived deletion mutation. J Bacteriol (1984) 3.41
Cloning and sequencing of Serratia protease gene. Nucleic Acids Res (1986) 2.72
Bacterial extracellular zinc-containing metalloproteases. Microbiol Rev (1993) 2.69
Structural gene and complete amino acid sequence of Pseudomonas aeruginosa IFO 3455 elastase. J Bacteriol (1989) 1.51
Extracellular and membrane-bound proteases from Bacillus subtilis. J Bacteriol (1980) 1.03
Purification and characterization of acidolysin, an acidic metalloprotease produced by Clostridium acetobutylicum ATCC 824. Appl Environ Microbiol (1990) 0.79
A fluorimetric study of the role of calcium ions in the stability of thermolysin. Biochem J (1977) 0.75
A protein sequenator. Eur J Biochem (1967) 17.03
Staphylococcal protease: a proteolytic enzyme specific for glutamoyl bonds. Proc Natl Acad Sci U S A (1972) 5.12
Application of sequenator analyses to the study of proteins. Biochemistry (1972) 3.88
Determination of the tryptophan content of proteins by ion exchange chromatography of alkaline hydrolysates. J Biol Chem (1972) 2.72
The conformation of thermolysin. J Biol Chem (1974) 2.25
An examination of conditions for the cleavage of polypeptide chains with cyanogen bromide: application to catalase. Arch Biochem Biophys (1969) 2.23
The structure of thermolysin: an electron density map at 2-3 A resolution. J Mol Biol (1972) 1.77
Determination of the amino acid sequence of porcine trypsin by sequenator aalysis. Biochemistry (1973) 1.68
Modification of the single tryptophan residue of staphylococcal nuclease by a new mild oxidizing agent. J Biol Chem (1970) 1.51
Studies on the role of calcium in thermolysin. Biochemistry (1971) 1.38
Studies on the Bacillus subtilis neutral-protease- and Bacillus thermoproteolyticus thermolysin-catalyzed hydrolysis of dipeptide substrates. Biochemistry (1970) 1.35
Thermolysin: a zinc metalloenzyme. Biochem Biophys Res Commun (1969) 1.32
The cooperative binding of two calcium ions to the double site of apothermolysin. Biochemistry (1974) 1.31
N- AND C-TERMINAL RESIDUES IN BAKER'S YEAST CYTOCHROME C. J Biochem (1964) 1.17
Neutral proteases of the genus Bacillus. Biochem Biophys Res Commun (1969) 1.14
Control of 5-aminolaevulinate synthetase activity in Rhodopseudomonas spheroides. The involvement of sulphur metabolism. Biochem J (1973) 1.05
Affinity chromatography of thermolysin and of neutral proteases from B. subtilis. Biochem Biophys Res Commun (1973) 0.81
Human complement C3b inactivator: isolation, characterization, and demonstration of an absolute requirement for the serum protein beta1H for cleavage of C3b and C4b in solution. J Exp Med (1977) 7.89
Hormone-fuel interrelationships during fasting. J Clin Invest (1966) 6.44
Complement C3 convertase: cell surface restriction of beta1H control and generation of restriction on neuraminidase-treated cells. Proc Natl Acad Sci U S A (1978) 4.94
Ovalbumin: a secreted protein without a transient hydrophobic leader sequence. Proc Natl Acad Sci U S A (1978) 4.46
Application of sequenator analyses to the study of proteins. Biochemistry (1972) 3.88
Evolution of proteolytic enzymes. Science (1984) 3.57
The leukocyte common antigen (CD45): a putative receptor-linked protein tyrosine phosphatase. Proc Natl Acad Sci U S A (1988) 3.57
Deficiency of an erythrocyte membrane protein with complement regulatory activity in paroxysmal nocturnal hemoglobinuria. Proc Natl Acad Sci U S A (1983) 3.47
Wound-induced proteinase inhibitors from tomato leaves. II. The cDNA-deduced primary structure of pre-inhibitor II. J Biol Chem (1985) 3.44
Recoverin: a calcium sensitive activator of retinal rod guanylate cyclase. Science (1991) 3.27
Demonstration that the leukocyte common antigen CD45 is a protein tyrosine phosphatase. Biochemistry (1988) 3.23
Complete amino acid sequence of the catalytic subunit of bovine cardiac muscle cyclic AMP-dependent protein kinase. Proc Natl Acad Sci U S A (1981) 3.07
A novel sialic acid binding site on factor H mediates serum resistance of sialylated Neisseria gonorrhoeae. J Exp Med (1998) 3.03
Anticoagulant properties of bovine plasma protein C following activation by thrombin. Biochemistry (1977) 2.96
cDNA isolated from a human T-cell library encodes a member of the protein-tyrosine-phosphatase family. Proc Natl Acad Sci U S A (1989) 2.95
Relation of putative thioester bond in C3 to activation of the alternative pathway and the binding of C3b to biological targets of complement. J Exp Med (1980) 2.94
Formation of the initial C3 convertase of the alternative complement pathway. Acquisition of C3b-like activities by spontaneous hydrolysis of the putative thioester in native C3. J Exp Med (1981) 2.88
Discrimination between activators and nonactivators of the alternative pathway of complement: regulation via a sialic acid/polyanion binding site on factor H. Proc Natl Acad Sci U S A (1990) 2.79
Prevention of C3 deposition by capsular polysaccharide is a virulence mechanism of type III group B streptococci. Infect Immun (1992) 2.73
Amino acid sequence of human von Willebrand factor. Biochemistry (1986) 2.73
Guanosine cyclic 3',5'-phosphate dependent protein kinase, a chimeric protein homologous with two separate protein families. Biochemistry (1984) 2.62
Initiation of the alternative pathway of complement: recognition of activators by bound C3b and assembly of the entire pathway from six isolated proteins. Proc Natl Acad Sci U S A (1978) 2.57
The phylogeny of trypsin-related serine proteases and their zymogens. New methods for the investigation of distant evolutionary relationships. J Mol Biol (1975) 2.47
Human placenta protein-tyrosine-phosphatase: amino acid sequence and relationship to a family of receptor-like proteins. Proc Natl Acad Sci U S A (1989) 2.40
Amino acid sequence of Escherichia coli alkaline phosphatase. Proc Natl Acad Sci U S A (1981) 2.35
Binding of complement factor H to loop 5 of porin protein 1A: a molecular mechanism of serum resistance of nonsialylated Neisseria gonorrhoeae. J Exp Med (1998) 2.24
Intracellular trafficking of furin is modulated by the phosphorylation state of a casein kinase II site in its cytoplasmic tail. EMBO J (1995) 2.22
Amino acid sequence of the catalytic subunit of bovine type II adenosine cyclic 3',5'-phosphate dependent protein kinase. Biochemistry (1983) 2.18
Covalent structure of a group-specific protease from rat small intestine. Appendix: crystallographic data for a group specific protease from rat intestine. Biochemistry (1978) 2.17
Amino acid sequence of monkey amyloid protein A. Biochemistry (1972) 2.17
Proteolytic activation of protein C from bovine plasma. Biochemistry (1976) 2.12
Role of proteolytic enzymes in biological regulation (a review). Proc Natl Acad Sci U S A (1976) 2.12
Breakdown of C3 after complement activation. Identification of a new fragment C3g, using monoclonal antibodies. J Exp Med (1982) 2.04
Selective oxidation of methionine residues in proteins. Biochemistry (1975) 2.03
The alternative pathway of complement. Springer Semin Immunopathol (1984) 2.01
Identification of the calmodulin-binding domain of skeletal muscle myosin light chain kinase. Proc Natl Acad Sci U S A (1985) 2.00
Complete amino acid sequence of rabbit muscle glycogen phosphorylase. Proc Natl Acad Sci U S A (1977) 2.00
Interpreting DNA mixtures. J Forensic Sci (1997) 1.97
Precursor of egg white lysozyme. Amino acid sequence of an NH2-terminal extension. J Biol Chem (1977) 1.93
PspC, a pneumococcal surface protein, binds human factor H. Infect Immun (2001) 1.92
Binding of C4b-binding protein to porin: a molecular mechanism of serum resistance of Neisseria gonorrhoeae. J Exp Med (2001) 1.91
Identification of three physically and functionally distinct binding sites for C3b in human complement factor H by deletion mutagenesis. Proc Natl Acad Sci U S A (1996) 1.91
Identification of disulfide-bridged substructures within human von Willebrand factor. Biochemistry (1987) 1.89
Evolution of structure and function of proteases. Science (1967) 1.89
Murine tissue amyloid protein AA. NH2-terminal sequence identity with only one of two serum amyloid protein (ApoSAA) gene products. J Exp Med (1984) 1.88
Paroxysmal nocturnal hemoglobinuria: deficiency in factor H-like functions of the abnormal erythrocytes. J Exp Med (1983) 1.83
Primary structures of N-terminal extra peptide segments linked to the variable and constant regions of immunoglobulin light chain precursors: implications on the organization and controlled expression of immunoglobulin genes. Biochemistry (1978) 1.82
Comparison of amino acid sequence of bovine coagulation Factor IX (Christmas Factor) with that of other vitamin K-dependent plasma proteins. Proc Natl Acad Sci U S A (1979) 1.77
Covalently bound myristate in a lymphoma tyrosine protein kinase. Proc Natl Acad Sci U S A (1984) 1.76
Amino acid sequence of the NH2-terminal extra piece segments of the precursors of mouse immunoglobulin lambda1-type and kappa-type light chains. Proc Natl Acad Sci U S A (1977) 1.75
Amino acid sequence of the regulatory subunit of bovine type I adenosine cyclic 3',5'-phosphate dependent protein kinase. Biochemistry (1984) 1.74
Identification of a conserved domain among cyclic nucleotide phosphodiesterases from diverse species. Proc Natl Acad Sci U S A (1986) 1.73
Homology of the gamma subunit of phosphorylase b kinase with cAMP-dependent protein kinase. Biochemistry (1984) 1.71
Proteolytic processing and physiological regulation. Trends Biochem Sci (1989) 1.69
Collagen type IX: evidence for covalent linkages to type II collagen in cartilage. FEBS Lett (1987) 1.69
Determination of the amino acid sequence of porcine trypsin by sequenator aalysis. Biochemistry (1973) 1.68
Activation of the alternative complement pathway: recognition of surface structures on activators by bound C3b. J Immunol (1980) 1.65
Identification of molecular species of glycerophospholipids and sphingomyelin using electrospray mass spectrometry. J Lipid Res (1994) 1.64
Mouse amyloid protein AA: Homology with nonimmunoglobulin protein of human and monkey amyloid substance. Proc Natl Acad Sci U S A (1976) 1.60
Primary structure of the regulatory subunit of type II cAMP-dependent protein kinase from bovine cardiac muscle. Proc Natl Acad Sci U S A (1982) 1.58
Nucleophilic modification of human complement protein C3: correlation of conformational changes with acquisition of C3b-like functional properties. Biochemistry (1981) 1.58
The amino acid sequence of bovine carboxypeptidase A. Proc Natl Acad Sci U S A (1969) 1.56
Identification of a noncatalytic cGMP-binding domain conserved in both the cGMP-stimulated and photoreceptor cyclic nucleotide phosphodiesterases. Proc Natl Acad Sci U S A (1990) 1.55
Marked hydrophobicity of the NH2-terminal extra piece of immunoglobulin light-chain precursors: possible physiological functions of the extra piece. Proc Natl Acad Sci U S A (1976) 1.54
Chicken immunoglobulin gamma-heavy chains: limited VH gene repertoire, combinatorial diversification by D gene segments and evolution of the heavy chain locus. EMBO J (1988) 1.53
C3b deposition during activation of the alternative complement pathway and the effect of deposition on the activating surface. J Immunol (1983) 1.52
Nephritogenic lambda light chain dimer: a unique human miniautoantibody against complement factor H. J Immunol (1999) 1.51
AN ESTIMATE OF THE RELATIVE DIMENSIONS AND DIFFUSION CONSTANT OF THE TOBACCO-MOSAIC VIRUS PROTEIN. Science (1938) 1.51
Species specificity of recognition by the alternative pathway of complement. J Immunol (1985) 1.49
Amino acid sequence of the calcium-dependent photoprotein aequorin. Biochemistry (1985) 1.49
Properdin binds to sulfatide [Gal(3-SO4)beta 1-1 Cer] and has a sequence homology with other proteins that bind sulfated glycoconjugates. J Biol Chem (1990) 1.49
Amino acid sequence of the beta subunit of bovine lung casein kinase II. Proc Natl Acad Sci U S A (1987) 1.44
Selective chemical cleavage of tryptophanyl peptide bonds by oxidative chlorination with N-chlorosuccinimide. Biochemistry (1976) 1.43
The contrasting mechanisms of serum resistance of Neisseria gonorrhoeae and group B Neisseria meningitidis. Mol Immunol (2000) 1.43
Specificity of the thioester-containing reactive site of human C3 and its significance to complement activation. Biochem J (1994) 1.42
The role of C3 fragments in endocytosis and extracellular cytotoxic reactions by polymorphonuclear leukocytes. Clin Immunol Immunopathol (1982) 1.42
Infantile idiopathic thrombocytopenic purpura. Pediatr Hematol Oncol (1990) 1.42