Published in J Virol on April 01, 1994
A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins. Nucleic Acids Res (1995) 7.95
Human cyclin E, a nuclear protein essential for the G1-to-S phase transition. Mol Cell Biol (1995) 6.41
CREB-binding protein cooperates with transcription factor GATA-1 and is required for erythroid differentiation. Proc Natl Acad Sci U S A (1998) 3.22
Cytomegalovirus infection induces high levels of cyclins, phosphorylated Rb, and p53, leading to cell cycle arrest. J Virol (1995) 3.18
Repression of cyclin D1: a novel function of MYC. Mol Cell Biol (1994) 2.67
B-cell proliferation and induction of early G1-regulating proteins by Epstein-Barr virus mutants conditional for EBNA2. EMBO J (1995) 2.51
Inhibition of cyclin D1 kinase activity is associated with E2F-mediated inhibition of cyclin D1 promoter activity through E2F and Sp1. Mol Cell Biol (1998) 2.10
Cell cycle regulation of the murine cyclin E gene depends on an E2F binding site in the promoter. Mol Cell Biol (1996) 1.97
Sequential activation of cyclin E and cyclin A gene expression by human papillomavirus type 16 E7 through sequences necessary for transformation. J Virol (1995) 1.52
Upstream stimulatory factor regulates expression of the cell cycle-dependent cyclin B1 gene promoter. Mol Cell Biol (1995) 1.43
Timing of cyclin E gene expression depends on the regulated association of a bipartite repressor element with a novel E2F complex. EMBO J (1999) 1.39
Expression of E1A in terminally differentiated muscle cells reactivates the cell cycle and suppresses tissue-specific genes by separable mechanisms. Mol Cell Biol (1996) 1.33
Network calisthenics: control of E2F dynamics in cell cycle entry. Cell Cycle (2011) 1.25
Strategic attack on host cell gene expression during adenovirus infection. J Virol (2003) 1.21
Ras induces anchorage-independent growth by subverting multiple adhesion-regulated cell cycle events. Mol Cell Biol (1996) 1.19
Identification of direct transcriptional targets of the Kaposi's sarcoma-associated herpesvirus Rta lytic switch protein by conditional nuclear localization. J Virol (2008) 1.08
Suppression of mutations in two Saccharomyces cerevisiae genes by the adenovirus E1A protein. Mol Cell Biol (1995) 1.07
Oncogene-induced sensitization to chemotherapy-induced death requires induction as well as deregulation of E2F1. Cancer Res (2010) 0.94
The other side of the coin: the tumor-suppressive aspect of oncogenes and the oncogenic aspect of tumor-suppressive genes, such as those along the CCND-CDK4/6-RB axis. Cell Cycle (2014) 0.94
Adenovirus E1A activates cyclin A gene transcription in the absence of growth factors through interaction with p107. J Virol (1996) 0.91
Conditional site-specific integration into human chromosome 19 by using a ligand-dependent chimeric adeno-associated virus/Rep protein. J Virol (2000) 0.88
Merkel cell polyomavirus T antigens promote cell proliferation and inflammatory cytokine gene expression. J Gen Virol (2015) 0.78
A novel E1A domain mediates skeletal-muscle-specific enhancer repression independently of pRB and p300 binding. Mol Cell Biol (1996) 0.78
Repression of cyclin D1 expression does not contribute to initiation or maintenance of cell transformation by adenovirus type 5 E1. J Virol (1996) 0.77
Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product. Nature (1988) 10.98
E2F: a link between the Rb tumor suppressor protein and viral oncoproteins. Science (1992) 10.28
The E2F transcription factor is a cellular target for the RB protein. Cell (1991) 9.62
Mammalian G1 cyclins. Cell (1993) 9.04
The role of cyclin synthesis and degradation in the control of maturation promoting factor activity. Nature (1989) 8.69
Cyclin D1 is a nuclear protein required for cell cycle progression in G1. Genes Dev (1993) 8.03
Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle. Cell (1991) 8.00
Cyclin A is required at two points in the human cell cycle. EMBO J (1992) 7.96
Regulation of retinoblastoma protein functions by ectopic expression of human cyclins. Cell (1992) 7.61
Cellular targets for transformation by the adenovirus E1A proteins. Cell (1989) 7.53
Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts. Genes Dev (1993) 7.41
Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4. Genes Dev (1993) 7.40
Localisation of the oestradiol-binding and putative DNA-binding domains of the human oestrogen receptor. EMBO J (1986) 6.08
Adenovirus promoters and E1A transactivation. Annu Rev Genet (1986) 5.86
The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F. Genes Dev (1992) 5.73
A family of human cdc2-related protein kinases. EMBO J (1992) 4.96
The MYC protein activates transcription of the alpha-prothymosin gene. EMBO J (1991) 4.96
Human cyclin E, a new cyclin that interacts with two members of the CDC2 gene family. Cell (1991) 4.88
Cyclin-dependent regulation of G1 in mammalian fibroblasts. Science (1993) 4.81
The retinoblastoma gene product regulates progression through the G1 phase of the cell cycle. Cell (1991) 4.69
Adenovirus E1a prevents the retinoblastoma gene product from complexing with a cellular transcription factor. Nature (1991) 4.62
Viruses in human cancers. Science (1991) 4.58
Isolation of the human cdk2 gene that encodes the cyclin A- and adenovirus E1A-associated p33 kinase. Nature (1991) 4.36
The T/E1A-binding domain of the retinoblastoma product can interact selectively with a sequence-specific DNA-binding protein. Cell (1991) 4.24
Multiple functional domains in the adenovirus E1A gene. Cell (1987) 4.22
A movable and regulable inactivation function within the steroid binding domain of the glucocorticoid receptor. Cell (1988) 4.15
Cyclin E/cdk2 and cyclin A/cdk2 kinases associate with p107 and E2F in a temporally distinct manner. Genes Dev (1992) 3.96
Cyclins and cyclin-dependent kinases: take your partners. Trends Biochem Sci (1993) 3.48
Homologous sequences in adenovirus E1A and human papillomavirus E7 proteins mediate interaction with the same set of cellular proteins. J Virol (1992) 2.97
Transcriptional repression of the E2-containing promoters EIIaE, c-myc, and RB1 by the product of the RB1 gene. Mol Cell Biol (1992) 2.78
Interactions of the p107 and Rb proteins with E2F during the cell proliferation response. EMBO J (1993) 2.70
Growth-regulated expression of D-type cyclin genes in human diploid fibroblasts. Proc Natl Acad Sci U S A (1992) 2.43
Association of cdk2 kinase with the transcription factor E2F during S phase. Science (1992) 2.37
Adenovirus E1a prevents the retinoblastoma gene product from repressing the activity of a cellular transcription factor. EMBO J (1992) 2.11
Simian virus 40 large T antigen: the puzzle, the pieces, and the emerging picture. J Virol (1992) 2.02
An intron within the 16S ribosomal RNA gene of the archaeon Pyrobaculum aerophilum. Proc Natl Acad Sci U S A (1993) 1.72
Cyclin E and cyclin A as candidates for the restriction point protein. Cancer Res (1993) 1.57
Binding of the human E2F transcription factor to the retinoblastoma protein but not to cyclin A is abolished in HPV-16-immortalized cells. Oncogene (1992) 1.46
E1A induces phosphorylation of the retinoblastoma protein independently of direct physical association between the E1A and retinoblastoma products. Mol Cell Biol (1991) 1.41
HPV16 E7 protein associates with the protein kinase p33CDK2 and cyclin A. Oncogene (1993) 1.40
Steroid-binding domains for regulating the functions of heterologous proteins in cis. Trends Cell Biol (1993) 1.21
Cooperative binding of two E2F molecules to an Ela-responsive promoter is triggered by the adenovirus Ela, but not by a cellular Ela-like activity. EMBO J (1989) 1.16
Cyclin A, cell cycle control and oncogenesis. Prog Growth Factor Res (1991) 0.93
Concentration of Indole-3-acetic Acid and Its Derivatives in Plants. Plant Physiol (1977) 10.03
SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27. Nat Cell Biol (1999) 9.92
hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization. Cell (1997) 8.74
Design and validation of a tool for neurite tracing and analysis in fluorescence microscopy images. Cytometry A (2004) 8.65
Cyclin D1 is a nuclear protein required for cell cycle progression in G1. Genes Dev (1993) 8.03
Concentrations of Indole-3-acetic Acid and Its Esters in Avena and Zea. Plant Physiol (1974) 7.28
p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest. Cell (1994) 7.05
The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis. Nature (2001) 6.73
Human cyclin E, a nuclear protein essential for the G1-to-S phase transition. Mol Cell Biol (1995) 6.41
Synthesis of 4,5,6,7 and 2,4,5,6,7 Deuterium-labeled Indole-3-Acetic Acid for Use in Mass Spectrometric Assays. Plant Physiol (1980) 6.14
A lymphocyte-specific enhancer in the mouse immunoglobulin kappa gene. Nature (1984) 6.05
Association of human cyclin E with a periodic G1-S phase protein kinase. Science (1992) 5.98
Binding of a specific ligand inhibits import of a purified precursor protein into mitochondria. Nature (1986) 5.58
Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice. Nature (1994) 5.34
Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas. Nat Med (1997) 5.10
Rapid destruction of human Cdc25A in response to DNA damage. Science (2000) 4.74
Chimaeras of myc oncoprotein and steroid receptors cause hormone-dependent transformation of cells. Nature (1989) 4.65
Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex. Nature (2000) 4.52
Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1. Mol Cell Biol (1997) 4.36
Repression of p15INK4b expression by Myc through association with Miz-1. Nat Cell Biol (2001) 4.22
Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation. Genes Dev (1999) 4.07
Short-term effects of carbon monoxide exposure on the exercise performance of subjects with coronary artery disease. N Engl J Med (1989) 4.02
The F-box protein family. Genome Biol (2000) 4.00
Double-standard isotope dilution assay. I. Quantitative assay of indole-3-acetic acid. Anal Biochem (1981) 3.90
The cell-cycle regulatory protein Cks1 is required for SCF(Skp2)-mediated ubiquitinylation of p27. Nat Cell Biol (2001) 3.87
Centrosome duplication in mammalian somatic cells requires E2F and Cdk2-cyclin A. Nat Cell Biol (1999) 3.74
Viral load and disease progression in infants infected with human immunodeficiency virus type 1. Women and Infants Transmission Study Group. N Engl J Med (1997) 3.71
TGFbeta influences Myc, Miz-1 and Smad to control the CDK inhibitor p15INK4b. Nat Cell Biol (2001) 3.69
Photo-regulation of the ratio of ester to free indole-3-acetic acid. Biochem Biophys Res Commun (1977) 3.69
DNA damage signalling guards against activated oncogenes and tumour progression. Oncogene (2007) 3.67
Regulation of the cdk inhibitor p27 and its deregulation in cancer. J Cell Physiol (2000) 3.65
Activation of the unliganded estrogen receptor by EGF involves the MAP kinase pathway and direct phosphorylation. EMBO J (1996) 3.53
A human RNA polymerase II complex associated with SRB and DNA-repair proteins. Nature (1996) 3.50
Do clinical markers of barotrauma and oxygen toxicity explain interhospital variation in rates of chronic lung disease? The Neonatology Committee for the Developmental Network. Pediatrics (2000) 3.48
A human RNA polymerase II complex containing factors that modify chromatin structure. Mol Cell Biol (1998) 3.45
Direct induction of cyclin D2 by Myc contributes to cell cycle progression and sequestration of p27. EMBO J (1999) 3.41
Activation of an inducible c-FosER fusion protein causes loss of epithelial polarity and triggers epithelial-fibroblastoid cell conversion. Cell (1992) 3.37
The human F box protein beta-Trcp associates with the Cul1/Skp1 complex and regulates the stability of beta-catenin. Oncogene (1999) 3.36
Identification of a family of human F-box proteins. Curr Biol (1999) 3.31
Distribution of Free and Ester Indole-3-Acetic Acid in the Cortex and Stele of the Zea mays Mesocotyl. Plant Physiol (1982) 3.28
Mammalian Srb/Mediator complex is targeted by adenovirus E1A protein. Nature (1999) 3.24
Regulation of cyclin D2 gene expression by the Myc/Max/Mad network: Myc-dependent TRRAP recruitment and histone acetylation at the cyclin D2 promoter. Genes Dev (2001) 3.15
Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization. EMBO J (1999) 3.05
BRG1, a component of the SWI-SNF complex, is mutated in multiple human tumor cell lines. Cancer Res (2000) 3.01
The cdk2 kinase is required for the G1-to-S transition in mammalian cells. Oncogene (1993) 2.99
Vectors for constitutive and inducible gene expression in yeast. Methods Enzymol (1991) 2.88
Regulation of the cell cycle by the cdk2 protein kinase in cultured human fibroblasts. J Cell Biol (1993) 2.83
Cyclin D1 protein expression and function in human breast cancer. Int J Cancer (1994) 2.81
Mammalian G1- and S-phase checkpoints in response to DNA damage. Curr Opin Cell Biol (2001) 2.77
CHK2 kinase--a busy messenger. Nat Rev Mol Cell Biol (2001) 2.68
Repression of cyclin D1: a novel function of MYC. Mol Cell Biol (1994) 2.67
Accumulation of cyclin B1 requires E2F and cyclin-A-dependent rearrangement of the anaphase-promoting complex. Nature (1999) 2.63
Raf induces TGFbeta production while blocking its apoptotic but not invasive responses: a mechanism leading to increased malignancy in epithelial cells. Genes Dev (2000) 2.62
Validation of a radioimmunoassay for indole-3-acetic Acid using gas chromatography-selected ion monitoring-mass spectrometry. Plant Physiol (1981) 2.60
Pathways governing G1/S transition and their response to DNA damage. FEBS Lett (2001) 2.58
Role of the F-box protein Skp2 in lymphomagenesis. Proc Natl Acad Sci U S A (2001) 2.55
Response to gravity by Zea mays seedlings. I. Time course of the response. Plant Physiol (1984) 2.55
Altered regulation of G1 cyclins in senescent human diploid fibroblasts: accumulation of inactive cyclin E-Cdk2 and cyclin D1-Cdk2 complexes. Proc Natl Acad Sci U S A (1993) 2.55
c-mpl mutations are the cause of congenital amegakaryocytic thrombocytopenia. Blood (2001) 2.52
Signal transduction and transcriptional regulation by glucocorticoid receptor-LexA fusion proteins. Science (1988) 2.52
Helix packing in polytopic membrane proteins: role of glycine in transmembrane helix association. Biophys J (1999) 2.49
Risk of oral squamous cell carcinoma in 402 patients with oral lichen planus: a follow-up study in an Italian population. Oral Oncol (2004) 2.46
p27 cytoplasmic localization is regulated by phosphorylation on Ser10 and is not a prerequisite for its proteolysis. EMBO J (2001) 2.45
An alternative pathway for gene regulation by Myc. EMBO J (1997) 2.43
Effect of Deseeding on the Indole-3-acetic Acid Content of Shoots and Roots of Zea mays Seedlings. Plant Physiol (1983) 2.36
NAT, a human complex containing Srb polypeptides that functions as a negative regulator of activated transcription. Mol Cell (1998) 2.33
Differential modulation of cyclin gene expression by MYC. Proc Natl Acad Sci U S A (1993) 2.31
Phosphorylation of spliceosomal protein SAP 155 coupled with splicing catalysis. Genes Dev (1998) 2.30
A likelihood-based method for real-time estimation of the serial interval and reproductive number of an epidemic. Stat Med (2008) 2.29
Acute isoniazid neurotoxicity in an urban hospital. Pediatrics (1995) 2.28
Fusion of GAL4-VP16 to a steroid-binding domain provides a tool for gratuitous induction of galactose-responsive genes in yeast. Gene (1993) 2.26
Antimicrobial susceptibility of Acinetobacter species. Antimicrob Agents Chemother (1993) 2.23
Cell-type preference of immunoglobulin kappa and lambda gene promoters. EMBO J (1985) 2.22
Differential expression and regulation of Cyclin D1 protein in normal and tumor human cells: association with Cdk4 is required for Cyclin D1 function in G1 progression. Oncogene (1994) 2.18
The mitotic serine/threonine kinase Aurora2/AIK is regulated by phosphorylation and degradation. Oncogene (2000) 2.15
Activation of protein kinase C triggers its ubiquitination and degradation. Mol Cell Biol (1998) 2.15
Using treatment failure under effective directly observed short-course chemotherapy programs to identify patients with multidrug-resistant tuberculosis. Int J Tuberc Lung Dis (2000) 2.15
Correct transcription of a cloned mouse immunoglobulin gene in vivo. Proc Natl Acad Sci U S A (1983) 2.14
Cyclin D1 protein oscillates and is essential for cell cycle progression in human tumour cell lines. Oncogene (1994) 2.10
Cyclin D1 expression is regulated by the retinoblastoma protein. Proc Natl Acad Sci U S A (1994) 2.09
Both ATP and an energized inner membrane are required to import a purified precursor protein into mitochondria. EMBO J (1987) 2.08
Prognostic role of the cyclin-dependent kinase inhibitor p27 in non-small cell lung cancer. Cancer Res (1997) 2.05
Enhanced ribosomal association of p27(Kip1) mRNA is a mechanism contributing to accumulation during growth arrest. J Biol Chem (1997) 2.05
Wnt/beta-catenin signaling induces the expression and activity of betaTrCP ubiquitin ligase receptor. Mol Cell (2000) 2.02
The cell cycle inhibitor p27 is an independent prognostic marker in small (T1a,b) invasive breast carcinomas. Cancer Res (1997) 2.00
Hunger in children in the United States: potential behavioral and emotional correlates. Pediatrics (1998) 1.99
Nuclear Ca2+ concentration measured with specifically targeted recombinant aequorin. EMBO J (1993) 1.98
Cell cycle regulation of the murine cyclin E gene depends on an E2F binding site in the promoter. Mol Cell Biol (1996) 1.97
A cell cycle-regulated inhibitor of cyclin-dependent kinases. Proc Natl Acad Sci U S A (1994) 1.95
White matter disorders of prematurity: association with intraventricular hemorrhage and ventriculomegaly. The Developmental Epidemiology Network. J Pediatr (1999) 1.93
Identification of a Myc-dependent step during the formation of active G1 cyclin-cdk complexes. EMBO J (1995) 1.92
Loss or altered subcellular localization of p27 in Barrett's associated adenocarcinoma. Cancer Res (1998) 1.92
Gravitational effects on plant growth hormone concentration. Adv Space Res (1983) 1.91