Published in EMBO J on March 01, 1993
The retinoblastoma protein binds to a family of E2F transcription factors. Mol Cell Biol (1993) 3.75
An E2F-binding site mediates cell-cycle regulated repression of mouse B-myb transcription. EMBO J (1993) 3.48
E2F-4 switches from p130 to p107 and pRB in response to cell cycle reentry. Mol Cell Biol (1996) 3.40
Stable binding to E2F is not required for the retinoblastoma protein to activate transcription, promote differentiation, and suppress tumor cell growth. Genes Dev (1998) 3.01
Transcription of the E2F-1 gene is rendered cell cycle dependent by E2F DNA-binding sites within its promoter. Mol Cell Biol (1994) 2.95
Target gene specificity of E2F and pocket protein family members in living cells. Mol Cell Biol (2000) 2.85
Cell cycle-dependent and cell cycle-independent control of transcription by the Drosophila E2F/RB pathway. Genes Dev (2003) 2.73
p53-dependent G1 arrest involves pRB-related proteins and is disrupted by the human papillomavirus 16 E7 oncoprotein. Proc Natl Acad Sci U S A (1994) 2.63
Cell cycle regulation of the cyclin A gene promoter is mediated by a variant E2F site. Proc Natl Acad Sci U S A (1995) 2.48
Cyclin A/CDK2 binds directly to E2F-1 and inhibits the DNA-binding activity of E2F-1/DP-1 by phosphorylation. Mol Cell Biol (1994) 2.44
Cloning and characterization of E2F-2, a novel protein with the biochemical properties of transcription factor E2F. Mol Cell Biol (1993) 2.34
The p53-dependent effects of macrophage migration inhibitory factor revealed by gene targeting. Proc Natl Acad Sci U S A (2003) 2.29
E2F-5, a new E2F family member that interacts with p130 in vivo. Mol Cell Biol (1995) 2.26
A potent transrepression domain in the retinoblastoma protein induces a cell cycle arrest when bound to E2F sites. Proc Natl Acad Sci U S A (1995) 2.17
Overexpression of E2F-1 in rat embryo fibroblasts leads to neoplastic transformation. EMBO J (1994) 2.14
DNA tumor virus oncoproteins and retinoblastoma gene mutations share the ability to relieve the cell's requirement for cyclin D1 function in G1. J Cell Biol (1994) 2.11
DNA-binding and trans-activation properties of Drosophila E2F and DP proteins. Proc Natl Acad Sci U S A (1994) 2.08
In vivo association of E2F and DP family proteins. Mol Cell Biol (1995) 1.99
The transcription factor E2F-1 is a downstream target of RB action. Mol Cell Biol (1995) 1.97
Cell cycle regulation of the murine cyclin E gene depends on an E2F binding site in the promoter. Mol Cell Biol (1996) 1.97
p21(Waf1/Cip1) inhibition of cyclin E/Cdk2 activity prevents endoreduplication after mitotic spindle disruption. Mol Cell Biol (1999) 1.90
Role of pRb-related proteins in simian virus 40 large-T-antigen-mediated transformation. Mol Cell Biol (1995) 1.87
Expression of the E2F1 transcription factor overcomes type beta transforming growth factor-mediated growth suppression. Proc Natl Acad Sci U S A (1995) 1.81
Cyclin E and c-Myc promote cell proliferation in the presence of p16INK4a and of hypophosphorylated retinoblastoma family proteins. EMBO J (1997) 1.81
Subunit composition determines E2F DNA-binding site specificity. Mol Cell Biol (1997) 1.75
Independent regions of adenovirus E1A are required for binding to and dissociation of E2F-protein complexes. Mol Cell Biol (1993) 1.75
Identification of distinct roles for separate E1A domains in disruption of E2F complexes. Mol Cell Biol (1993) 1.75
RNA fingerprinting using arbitrarily primed PCR identifies differentially regulated RNAs in mink lung (Mv1Lu) cells growth arrested by transforming growth factor beta 1. Proc Natl Acad Sci U S A (1993) 1.72
Genetic characterization of a mammalian protein-protein interaction domain by using a yeast reverse two-hybrid system. Proc Natl Acad Sci U S A (1996) 1.72
A genetic analysis of the E2F1 gene distinguishes regulation by Rb, p107, and adenovirus E4. Mol Cell Biol (1993) 1.70
The pRB-related protein p107 contains two growth suppression domains: independent interactions with E2F and cyclin/cdk complexes. EMBO J (1995) 1.67
The human cytomegalovirus IE1-72 protein interacts with the cellular p107 protein and relieves p107-mediated transcriptional repression of an E2F-responsive promoter. J Virol (1996) 1.63
Cyclin A expression is under negative transcriptional control during the cell cycle. Mol Cell Biol (1996) 1.63
Expression of dominant-negative mutant DP-1 blocks cell cycle progression in G1. Mol Cell Biol (1996) 1.62
Differential roles of two tandem E2F sites in repression of the human p107 promoter by retinoblastoma and p107 proteins. Mol Cell Biol (1995) 1.61
Modulation of cyclin gene expression by adenovirus E1A in a cell line with E1A-dependent conditional proliferation. J Virol (1994) 1.46
p130 is dispensable in peripheral T lymphocytes: evidence for functional compensation by p107 and pRB. Mol Cell Biol (1998) 1.39
Inhibition of E2F activity by the cyclin-dependent protein kinase inhibitor p21 in cells expressing or lacking a functional retinoblastoma protein. Mol Cell Biol (1996) 1.37
Interaction of c-Myc with the pRb-related protein p107 results in inhibition of c-Myc-mediated transactivation. EMBO J (1994) 1.37
Phosphorylation of the adenovirus E1A-associated 300 kDa protein in response to retinoic acid and E1A during the differentiation of F9 cells. EMBO J (1995) 1.33
The E2F transcription factor activates a replication-dependent human H2A gene in early S phase of the cell cycle. Mol Cell Biol (1996) 1.32
Association of p107 with Sp1: genetically separable regions of p107 are involved in regulation of E2F- and Sp1-dependent transcription. Mol Cell Biol (1995) 1.32
Cell cycle analysis of E2F in primary human T cells reveals novel E2F complexes and biochemically distinct forms of free E2F. Mol Cell Biol (1993) 1.31
Association of the human papillomavirus type 16 E7 protein with the S-phase-specific E2F-cyclin A complex. Mol Cell Biol (1993) 1.28
HPV16 E7 oncoprotein deregulates B-myb expression: correlation with targeting of p107/E2F complexes. EMBO J (1994) 1.28
Cloning, chromosomal location, and characterization of mouse E2F1. Mol Cell Biol (1994) 1.25
BK virus large T antigen: interactions with the retinoblastoma family of tumor suppressor proteins and effects on cellular growth control. J Virol (1996) 1.22
Regulated expression and RNA processing of transcripts from the Srp20 splicing factor gene during the cell cycle. Mol Cell Biol (1997) 1.22
Complementary functions of E1a conserved region 1 cooperate with conserved region 3 to activate adenovirus serotype 5 early promoters. J Virol (1994) 1.21
E2F-1:DP-1 induces p53 and overrides survival factors to trigger apoptosis. Mol Cell Biol (1995) 1.20
Transcriptional repression and growth suppression by the p107 pocket protein. Mol Cell Biol (1996) 1.18
p21 Disrupts the interaction between cdk2 and the E2F-p130 complex. Mol Cell Biol (1996) 1.16
Dual cyclin-binding domains are required for p107 to function as a kinase inhibitor. Mol Cell Biol (1998) 1.14
Multiple change in E2F function and regulation occur upon muscle differentiation. Mol Cell Biol (1995) 1.10
The Rb-related p107 protein can suppress E2F function independently of binding to cyclin A/cdk2. Mol Cell Biol (1995) 1.09
Novel mechanisms of E2F induction by BK virus large-T antigen: requirement of both the pRb-binding and the J domains. Mol Cell Biol (1998) 1.09
Suppression of mutations in two Saccharomyces cerevisiae genes by the adenovirus E1A protein. Mol Cell Biol (1995) 1.07
Functional interaction between DP-1 and p53. Mol Cell Biol (1996) 1.06
Coordinated trans activation of DNA synthesis- and precursor-producing enzymes by polyomavirus large T antigen through interaction with the retinoblastoma protein. Mol Cell Biol (1994) 1.05
Mutually exclusive interaction of the adenovirus E4-6/7 protein and the retinoblastoma gene product with internal domains of E2F-1 and DP-1. J Virol (1994) 1.03
Molecular characterization of Xenopus laevis DP proteins. Mol Biol Cell (1994) 0.89
E2F mediates induction of the Sp1-controlled promoter of the human DNA polymerase epsilon B-subunit gene POLE2. Nucleic Acids Res (2001) 0.87
Proto-oncogene activity of melanoma antigen-A11 (MAGE-A11) regulates retinoblastoma-related p107 and E2F1 proteins. J Biol Chem (2013) 0.86
E2F and its developmental regulation in Xenopus laevis. Mol Cell Biol (1994) 0.84
The differential binding of E2F and CDF repressor complexes contributes to the timing of cell cycle-regulated transcription. Nucleic Acids Res (1997) 0.83
Altered shape and cell cycle characteristics of fibroblasts expressing the E2F1 transcription factor. Mol Biol Cell (1994) 0.82
Differential control of transcription by DNA-bound cyclins. Mol Biol Cell (2001) 0.82
Cyclin-dependent kinases phosphorylate the adenovirus E1A protein, enhancing its ability to bind pRb and disrupt pRb-E2F complexes. J Virol (1996) 0.82
Activation of a retinoblastoma-protein-dependent pathway by sphingosine. Biochem J (1995) 0.81
The adenovirus E1A protein overrides the requirement for cellular ras in initiating DNA synthesis. EMBO J (1994) 0.77
Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells. Mol Cell Biol (1982) 116.75
Firefly luciferase gene: structure and expression in mammalian cells. Mol Cell Biol (1987) 26.70
The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product. Science (1989) 16.54
Cloning, structure, and expression of the mitochondrial cytochrome P-450 sterol 26-hydroxylase, a bile acid biosynthetic enzyme. J Biol Chem (1989) 11.06
Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product. Nature (1988) 10.98
E2F: a link between the Rb tumor suppressor protein and viral oncoproteins. Science (1992) 10.28
The E2F transcription factor is a cellular target for the RB protein. Cell (1991) 9.62
Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties. Cell (1992) 9.19
Human cyclin A is adenovirus E1A-associated protein p60 and behaves differently from cyclin B. Nature (1990) 7.34
The retinoblastoma protein is phosphorylated during specific phases of the cell cycle. Cell (1989) 6.68
Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiation. Cell (1989) 6.46
The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element. Cell (1989) 6.43
Identification of a cellular transcription factor involved in E1A trans-activation. Cell (1986) 6.36
A cDNA encoding a pRB-binding protein with properties of the transcription factor E2F. Cell (1992) 6.32
The human papillomavirus type 16 E7 gene encodes transactivation and transformation functions similar to those of adenovirus E1A. Cell (1988) 6.28
The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F. Genes Dev (1992) 5.73
Retinoblastoma protein switches the E2F site from positive to negative element. Nature (1992) 5.47
The transcription factor E2F interacts with the retinoblastoma product and a p107-cyclin A complex in a cell cycle-regulated manner. Cell (1992) 5.05
Adenovirus E1a prevents the retinoblastoma gene product from complexing with a cellular transcription factor. Nature (1991) 4.62
Identification of a growth suppression domain within the retinoblastoma gene product. Genes Dev (1992) 4.56
The retinoblastoma protein copurifies with E2F-I, an E1A-regulated inhibitor of the transcription factor E2F. Cell (1991) 4.42
Isolation of the human cdk2 gene that encodes the cyclin A- and adenovirus E1A-associated p33 kinase. Nature (1991) 4.36
Adenovirus E1A, simian virus 40 tumor antigen, and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the retinoblastoma gene product. Proc Natl Acad Sci U S A (1992) 4.27
Independent binding of the retinoblastoma protein and p107 to the transcription factor E2F. Nature (1992) 4.21
Transcription factor E2F is required for efficient expression of the hamster dihydrofolate reductase gene in vitro and in vivo. Mol Cell Biol (1989) 4.10
Cell cycle regulation of the E2F transcription factor involves an interaction with cyclin A. Cell (1991) 3.98
Cyclin E/cdk2 and cyclin A/cdk2 kinases associate with p107 and E2F in a temporally distinct manner. Genes Dev (1992) 3.96
Adenovirus E1A proteins can dissociate heteromeric complexes involving the E2F transcription factor: a novel mechanism for E1A trans-activation. Cell (1990) 3.77
Cell cycle regulation of the human cdc2 gene. EMBO J (1992) 3.69
A cyclin A-protein kinase complex possesses sequence-specific DNA binding activity: p33cdk2 is a component of the E2F-cyclin A complex. Cell (1992) 3.64
Cell cycle-dependent regulation of phosphorylation of the human retinoblastoma gene product. Science (1989) 3.63
Molecular cloning, chromosomal mapping, and expression of the cDNA for p107, a retinoblastoma gene product-related protein. Cell (1991) 3.47
Cyclin A and the retinoblastoma gene product complex with a common transcription factor. Nature (1991) 3.15
The HIP1 binding site is required for growth regulation of the dihydrofolate reductase gene promoter. Mol Cell Biol (1992) 3.06
Adenovirus early region 4 encodes two gene products with redundant effects in lytic infection. J Virol (1989) 2.91
The adenovirus-inducible factor E2F stimulates transcription after specific DNA binding. Mol Cell Biol (1989) 2.83
Transcriptional repression of the E2-containing promoters EIIaE, c-myc, and RB1 by the product of the RB1 gene. Mol Cell Biol (1992) 2.78
Amino-terminal domains of c-myc and N-myc proteins mediate binding to the retinoblastoma gene product. Nature (1991) 2.78
Domains of the adenovirus E1A protein required for oncogenic activity are also required for dissociation of E2F transcription factor complexes. Genes Dev (1991) 2.40
Interaction of p107 with cyclin A independent of complex formation with viral oncoproteins. Science (1992) 2.39
Promoter interaction of the E1A-inducible factor E2F and its potential role in the formation of a multi-component complex. EMBO J (1987) 2.30
Adenovirus E1a prevents the retinoblastoma gene product from repressing the activity of a cellular transcription factor. EMBO J (1992) 2.11
An adenovirus E4 gene product trans-activates E2 transcription and stimulates stable E2F binding through a direct association with E2F. Proc Natl Acad Sci U S A (1990) 2.09
The adenovirus EIIA enhancer. Analysis of regulatory sequences and changes in binding activity of ATF and EIIF following adenovirus infection. J Biol Chem (1989) 1.93
An adenovirus early region 4 gene product is required for induction of the infection-specific form of cellular E2F activity. Genes Dev (1989) 1.82
The adenovirus E4 gene, in addition to the E1A gene, is important for trans-activation of E2 transcription and for E2F activation. J Virol (1989) 1.50
E2F from adenovirus-infected cells binds cooperatively to DNA containing two properly oriented and spaced recognition sites. Mol Cell Biol (1989) 1.40
Predicting the clinical status of human breast cancer by using gene expression profiles. Proc Natl Acad Sci U S A (2001) 13.30
The E2F transcription factor is a cellular target for the RB protein. Cell (1991) 9.62
Mechanism of activation of early viral transcription by the adenovirus E1A gene product. Cell (1981) 9.38
Expression of transcription factor E2F1 induces quiescent cells to enter S phase. Nature (1993) 6.84
Induction of the synthesis of a 70,000 dalton mammalian heat shock protein by the adenovirus E1A gene product. Cell (1982) 6.78
Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability. Genes Dev (2000) 6.54
Identification of a cellular transcription factor involved in E1A trans-activation. Cell (1986) 6.36
Steps in the processing of Ad2 mRNA: poly(A)+ nuclear sequences are conserved and poly(A) addition precedes splicing. Cell (1978) 6.36
Cellular targets for activation by the E2F1 transcription factor include DNA synthesis- and G1/S-regulatory genes. Mol Cell Biol (1995) 6.26
The pathway of eukaryotic mRNA formation. Annu Rev Biochem (1983) 6.16
Activation of gene expression by adenovirus and herpesvirus regulatory genes acting in trans and by a cis-acting adenovirus enhancer element. Cell (1983) 5.91
Distinct roles for E2F proteins in cell growth control and apoptosis. Proc Natl Acad Sci U S A (1997) 5.83
The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F. Genes Dev (1992) 5.73
Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis. Mol Cell Biol (2001) 5.03
Autoregulatory control of E2F1 expression in response to positive and negative regulators of cell cycle progression. Genes Dev (1994) 4.93
Requirement of a downstream sequence for generation of a poly(A) addition site. Cell (1984) 4.87
Common control of the heat shock gene and early adenovirus genes: evidence for a cellular E1A-like activity. Mol Cell Biol (1984) 4.76
Role of an adenovirus E2 promoter binding factor in E1A-mediated coordinate gene control. Proc Natl Acad Sci U S A (1987) 4.68
Regulation of adenovirus-2 gene expression at the level of transcriptional termination and RNA processing. Nature (1981) 4.46
The E2F1-3 transcription factors are essential for cellular proliferation. Nature (2001) 4.37
Adenovirus E1A, simian virus 40 tumor antigen, and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the retinoblastoma gene product. Proc Natl Acad Sci U S A (1992) 4.27
Transcriptional activation and subsequent control of the human heat shock gene during adenovirus infection. Mol Cell Biol (1983) 4.15
Cell cycle regulation of the E2F transcription factor involves an interaction with cyclin A. Cell (1991) 3.98
Regulation of the cyclin E gene by transcription factor E2F1. Proc Natl Acad Sci U S A (1995) 3.95
Definition of multiple, functionally distinct TATA elements, one of which is a target in the hsp70 promoter for E1A regulation. Cell (1988) 3.91
Adenovirus E1A proteins can dissociate heteromeric complexes involving the E2F transcription factor: a novel mechanism for E1A trans-activation. Cell (1990) 3.77
E1A-dependent trans-activation of the human MYC promoter is mediated by the E2F factor. Proc Natl Acad Sci U S A (1989) 3.67
Definition and mapping of adenovirus 2 nuclear transcription. Methods Enzymol (1980) 3.67
A cyclin A-protein kinase complex possesses sequence-specific DNA binding activity: p33cdk2 is a component of the E2F-cyclin A complex. Cell (1992) 3.64
E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis. J Virol (1995) 3.55
E2F3 activity is regulated during the cell cycle and is required for the induction of S phase. Genes Dev (1998) 3.48
Selective induction of E2F1 in response to DNA damage, mediated by ATM-dependent phosphorylation. Genes Dev (2001) 3.41
Activation of early adenovirus transcription by the herpesvirus immediate early gene: evidence for a common cellular control factor. Proc Natl Acad Sci U S A (1982) 3.29
Effect of adenovirus on metabolism of specific host mRNAs: transport control and specific translational discrimination. Mol Cell Biol (1983) 3.25
An enhancer-like element in the adenovirus E2 promoter contains sequences essential for uninduced and E1A-induced transcription. Proc Natl Acad Sci U S A (1985) 3.15
A role for the adenovirus inducible E2F transcription factor in a proliferation dependent signal transduction pathway. EMBO J (1990) 3.07
An ordered pathway of assembly of components required for polyadenylation site recognition and processing. Genes Dev (1989) 2.94
Regulation of the primary expression of the early adenovirus transcription units. J Virol (1979) 2.92
Ras enhances Myc protein stability. Mol Cell (1999) 2.91
Adenovirus 5 E2 transcription unit: an E1A-inducible promoter with an essential element that functions independently of position or orientation. Mol Cell Biol (1984) 2.88
The adenovirus-inducible factor E2F stimulates transcription after specific DNA binding. Mol Cell Biol (1989) 2.83
Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F. Nature (1997) 2.78
Poly(A) site cleavage in a HeLa nuclear extract is dependent on downstream sequences. Cell (1985) 2.72
Sequences capable of restoring poly(A) site function define two distinct downstream elements. EMBO J (1986) 2.69
Definition of essential sequences and functional equivalence of elements downstream of the adenovirus E2A and the early simian virus 40 polyadenylation sites. Mol Cell Biol (1985) 2.65
E1A transcription induction: enhanced binding of a factor to upstream promoter sequences. Science (1986) 2.49
E2F4 and E2F5 play an essential role in pocket protein-mediated G1 control. Mol Cell (2000) 2.48
The accumulation of an E2F-p130 transcriptional repressor distinguishes a G0 cell state from a G1 cell state. Mol Cell Biol (1996) 2.47
The stability of early adenovirus mRNA is controlled by the viral 72 kd DNA-binding protein. Cell (1981) 2.44
Multiple factors are required for specific RNA cleavage at a poly(A) addition site. Genes Dev (1988) 2.43
Regulation of early adenovirus transcription: a protein product of early region 2 specifically represses region 4 transcription. Proc Natl Acad Sci U S A (1980) 2.42
Cdc6 is regulated by E2F and is essential for DNA replication in mammalian cells. Proc Natl Acad Sci U S A (1998) 2.40
Identification of an E1A-inducible cellular factor that interacts with regulatory sequences within the adenovirus E4 promoter. EMBO J (1987) 2.40
Domains of the adenovirus E1A protein required for oncogenic activity are also required for dissociation of E2F transcription factor complexes. Genes Dev (1991) 2.40
A unique role for the Rb protein in controlling E2F accumulation during cell growth and differentiation. Proc Natl Acad Sci U S A (1996) 2.36
Localization of the adenovirus E1Aa protein, a positive-acting transcriptional factor, in infected cells infected cells. Mol Cell Biol (1983) 2.36
The reliability, validity, and taxonomic structure of the oral examination. J Med Educ (1966) 2.36
Poly(A) site efficiency reflects the stability of complex formation involving the downstream element. EMBO J (1991) 2.30
Promoter interaction of the E1A-inducible factor E2F and its potential role in the formation of a multi-component complex. EMBO J (1987) 2.30
Inhibition of cyclin D-CDK4/CDK6 activity is associated with an E2F-mediated induction of cyclin kinase inhibitor activity. Proc Natl Acad Sci U S A (1996) 2.30
Developmental control of a promoter-specific factor that is also regulated by the E1A gene product. Cell (1987) 2.29
Myc requires distinct E2F activities to induce S phase and apoptosis. Mol Cell (2001) 2.29
The zebrafish slow-muscle-omitted gene product is required for Hedgehog signal transduction and the development of slow muscle identity. Development (2000) 2.25
Oncogenic capacity of the E2F1 gene. Proc Natl Acad Sci U S A (1994) 2.24
Identification of a novel E2F3 product suggests a mechanism for determining specificity of repression by Rb proteins. Mol Cell Biol (2000) 2.24
Activation of a preexisting cellular factor as a basis for adenovirus E1A-mediated transcription control. Proc Natl Acad Sci U S A (1988) 2.16
Molecular analyses of two poly(A) site-processing factors that determine the recognition and efficiency of cleavage of the pre-mRNA. Mol Cell Biol (1991) 2.15
Transcription units of adenovirus type 2. Termination of transcription beyond the poly(A) addition site in early regions 2 and 4. J Mol Biol (1980) 2.11
An adenovirus E4 gene product trans-activates E2 transcription and stimulates stable E2F binding through a direct association with E2F. Proc Natl Acad Sci U S A (1990) 2.09
Relative position and strengths of poly(A) sites as well as transcription termination are critical to membrane versus secreted mu-chain expression during B-cell development. Genes Dev (1987) 2.07
Ectopic E2F expression induces S phase and apoptosis in Drosophila imaginal discs. Genes Dev (1996) 2.06
Groups of adenovirus type 2 mRNA's derived from a large primary transcript: probable nuclear origin and possible common 3' ends. J Virol (1978) 2.06
The major late adenovirus type-2 transcription unit: termination is downstream from the last poly(A) site. J Mol Biol (1979) 2.04
Tetanus in a London Sector in Two Years of War. Proc R Soc Med (1942) 2.01
Cell cycle control of the human HSP70 gene: implications for the role of a cellular E1A-like function. Mol Cell Biol (1985) 2.01
The HTLV-I Rex response element mediates a novel form of mRNA polyadenylation. Cell (1991) 2.00
Identification of positively and negatively acting elements regulating expression of the E2F2 gene in response to cell growth signals. Mol Cell Biol (1997) 2.00
Anchorage-independent cell growth signature identifies tumors with metastatic potential. Oncogene (2009) 1.99
E2F1-specific induction of apoptosis and p53 accumulation, which is blocked by Mdm2. Cell Growth Differ (1998) 1.96
E2F-1 accumulation bypasses a G1 arrest resulting from the inhibition of G1 cyclin-dependent kinase activity. Genes Dev (1995) 1.95
Host gene control of endogenous avian leukosis virus production. Virology (1974) 1.94
Role of E2F transcription factor in E1A-mediated trans activation of cellular genes. J Virol (1991) 1.92
Loss of E2F4 activity leads to abnormal development of multiple cellular lineages. Mol Cell (2000) 1.86
Isolation and properties of the vaccinia virus DNA-dependent RNA polymerase. J Biol Chem (1977) 1.85
Replication factors MCM2 and ORC1 interact with the histone acetyltransferase HBO1. J Biol Chem (2001) 1.85
Expression of the HsOrc1 gene, a human ORC1 homolog, is regulated by cell proliferation via the E2F transcription factor. Mol Cell Biol (1996) 1.83