Published in Am J Med Genet on March 15, 1994
Effect of COMT Val108/158 Met genotype on frontal lobe function and risk for schizophrenia. Proc Natl Acad Sci U S A (2001) 9.42
Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: Schizophrenia. Am J Hum Genet (2003) 6.63
Schizophrenia susceptibility associated with interstitial deletions of chromosome 22q11. Proc Natl Acad Sci U S A (1995) 5.62
Bipolar I disorder and schizophrenia: a 440-single-nucleotide polymorphism screen of 64 candidate genes among Ashkenazi Jewish case-parent trios. Am J Hum Genet (2005) 3.03
A genomewide screen for schizophrenia genes in an isolated Finnish subpopulation, suggesting multiple susceptibility loci. Am J Hum Genet (1999) 2.15
Schizophrenia and 22q11.2 deletion syndrome. Curr Psychiatry Rep (2008) 2.02
Multicenter linkage study of schizophrenia candidate regions on chromosomes 5q, 6q, 10p, and 13q: schizophrenia linkage collaborative group III. Am J Hum Genet (2000) 1.68
A genome survey indicates a possible susceptibility locus for bipolar disorder on chromosome 22. Proc Natl Acad Sci U S A (2001) 1.64
A third member of the synapsin gene family. Proc Natl Acad Sci U S A (1998) 1.52
Genetics of schizophrenia and the new millennium: progress and pitfalls. Am J Hum Genet (2001) 1.33
Genome-wide linkage analyses of 12 endophenotypes for schizophrenia from the Consortium on the Genetics of Schizophrenia. Am J Psychiatry (2013) 1.30
MicroRNAs in psychiatric and neurodevelopmental disorders. Brain Res (2010) 1.22
Schizophrenia and chromosomal deletions within 22q11.2. Am J Hum Genet (1995) 1.21
Splitting schizophrenia: periodic catatonia-susceptibility locus on chromosome 15q15. Am J Hum Genet (2000) 1.17
Three independent lines of evidence suggest retinoids as causal to schizophrenia. Proc Natl Acad Sci U S A (1998) 1.15
Behavior of mice with mutations in the conserved region deleted in velocardiofacial/DiGeorge syndrome. Neurogenetics (2006) 1.14
Polygenic transmission and complex neuro developmental network for attention deficit hyperactivity disorder: genome-wide association study of both common and rare variants. Am J Med Genet B Neuropsychiatr Genet (2013) 1.11
Genomewide high-density SNP linkage analysis of 236 Japanese families supports the existence of schizophrenia susceptibility loci on chromosomes 1p, 14q, and 20p. Am J Hum Genet (2005) 1.11
Low-voltage-activated ("T-Type") calcium channels in review. J Bioenerg Biomembr (2003) 1.06
Bipolar disorder and schizophrenia: not so distant relatives? World Psychiatry (2003) 0.98
Satellog: a database for the identification and prioritization of satellite repeats in disease association studies. BMC Bioinformatics (2005) 0.97
Family-based association of YWHAH in psychotic bipolar disorder. Am J Med Genet B Neuropsychiatr Genet (2009) 0.93
Deletion of PLCB1 gene in schizophrenia-affected patients. J Cell Mol Med (2012) 0.91
Long Noncoding RNA-Directed Epigenetic Regulation of Gene Expression Is Associated With Anxiety-like Behavior in Mice. Biol Psychiatry (2015) 0.86
Schizophrenia: genetic tools for unraveling the nature of a complex disorder. Proc Natl Acad Sci U S A (1995) 0.85
Exploring metabolic pathway disruption in the subchronic phencyclidine model of schizophrenia with the Generalized Singular Value Decomposition. BMC Syst Biol (2011) 0.82
Heritability and genome-wide SNP linkage analysis of temperament in bipolar disorder. J Affect Disord (2013) 0.78
Molecular linkage studies of bipolar disorder. Dialogues Clin Neurosci (1999) 0.77
Neurodevelopment in schizophrenia: the role of the wnt pathways. Curr Neuropharmacol (2013) 0.77
New discoveries in schizophrenia genetics reveal neurobiological pathways: A review of recent findings. Eur J Med Genet (2015) 0.77
Linkage and Association Analyses of Schizophrenia with Genetic Variations on Chromosome 22q11 in Koreans. Psychiatry Investig (2016) 0.75
Dysregulated 14-3-3 Family in Peripheral Blood Leukocytes of Patients with Schizophrenia. Sci Rep (2016) 0.75
Likelihood ratio testing for admixture models with application to genetic linkage analysis. Biometrics (2011) 0.75
Polymorphism of the CLDN5 gene and Schizophrenia in an Iranian Population. Iran J Public Health (2014) 0.75
High-resolution mapping of human chromosome 11 by in situ hybridization with cosmid clones. Science (1990) 10.72
Linkage of beta-thalassaemia mutations and beta-globin gene polymorphisms with DNA polymorphisms in human beta-globin gene cluster. Nature (1982) 9.47
High frequency retrotransposition in cultured mammalian cells. Cell (1996) 8.60
Characterization of beta-thalassaemia mutations using direct genomic sequencing of amplified single copy DNA. Nature (1987) 8.58
Human L1 retrotransposon encodes a conserved endonuclease required for retrotransposition. Cell (1996) 8.21
Nonuniform recombination within the human beta-globin gene cluster. Am J Hum Genet (1984) 7.97
WT-1 is required for early kidney development. Cell (1993) 7.05
Biology of mammalian L1 retrotransposons. Annu Rev Genet (2001) 6.52
Beta-globin locus is linked to the parathyroid hormone (PTH) locus and lies between the insulin and PTH loci in man. Proc Natl Acad Sci U S A (1983) 6.50
Guidelines for human gene nomenclature (1997). HUGO Nomenclature Committee. Genomics (1997) 6.44
Many human L1 elements are capable of retrotransposition. Nat Genet (1997) 6.27
Synthesis of and chains of rabbit hemoglobin in a cell-free extract from Krebs II ascites cells. Proc Natl Acad Sci U S A (1971) 5.92
Reverse transcriptase encoded by a human transposable element. Science (1991) 5.86
Nonrandom association of polymorphic restriction sites in the beta-globin gene cluster. Proc Natl Acad Sci U S A (1982) 5.85
Isolation and localization of DNA segments from specific human chromosomes. Proc Natl Acad Sci U S A (1980) 5.76
The mutation and polymorphism of the human beta-globin gene and its surrounding DNA. Annu Rev Genet (1984) 5.74
Schizophrenia susceptibility associated with interstitial deletions of chromosome 22q11. Proc Natl Acad Sci U S A (1995) 5.62
Mammalian multidrug resistance gene: complete cDNA sequence indicates strong homology to bacterial transport proteins. Cell (1986) 5.51
A cluster of cystic fibrosis mutations in the first nucleotide-binding fold of the cystic fibrosis conductance regulator protein. Nature (1990) 5.42
Human L1 retrotransposition: cis preference versus trans complementation. Mol Cell Biol (2001) 5.23
Report of the Committee on the Genetic Constitution of Chromosomes 10, 11, and 12. Cytogenet Cell Genet (1985) 5.01
Exon shuffling by L1 retrotransposition. Science (1999) 4.99
Health and mental health problems of homeless men and women in Baltimore. JAMA (1989) 4.29
Inversions disrupting the factor VIII gene are a common cause of severe haemophilia A. Nat Genet (1993) 4.12
Foci of trinucleotide repeat transcripts in nuclei of myotonic dystrophy cells and tissues. J Cell Biol (1995) 4.04
Initiation of haemoglobin synthesis by methionyl-tRNA. Nature (1970) 3.99
Catechol-O-methyltransferase-deficient mice exhibit sexually dimorphic changes in catecholamine levels and behavior. Proc Natl Acad Sci U S A (1998) 3.99
Isolation of an active human transposable element. Science (1991) 3.99
Targeted disruption of the mouse factor VIII gene produces a model of haemophilia A. Nat Genet (1995) 3.74
Germline mutations in the ribonuclease L gene in families showing linkage with HPC1. Nat Genet (2002) 3.67
Presymptomatic diagnosis of delayed-onset disease with linked DNA markers. The experience in Huntington's disease. JAMA (1989) 3.65
Single-sperm typing: determination of genetic distance between the G gamma-globin and parathyroid hormone loci by using the polymerase chain reaction and allele-specific oligomers. Proc Natl Acad Sci U S A (1989) 3.50
Initiation of hemoglobin synthesis. Specific inhibition by antibiotics and bacteriophage ribonucleic acid. Biochemistry (1971) 3.50
LRRTM1 on chromosome 2p12 is a maternally suppressed gene that is associated paternally with handedness and schizophrenia. Mol Psychiatry (2007) 3.49
Insoluble detergent-resistant aggregates form between pathological and nonpathological lengths of polyglutamine in mammalian cells. Proc Natl Acad Sci U S A (1999) 3.33
The candidate Wilms' tumour gene is involved in genitourinary development. Nature (1990) 3.13
Psychotic illness in patients diagnosed with velo-cardio-facial syndrome and their relatives. J Nerv Ment Dis (1994) 3.12
Precise localization of human beta-globin gene complex on chromosome 11. Proc Natl Acad Sci U S A (1979) 3.05
ApoE-4 and age at onset of Alzheimer's disease: the NIMH genetics initiative. Neurology (1997) 3.04
Schizophrenia susceptibility loci on chromosomes 13q32 and 8p21. Nat Genet (1998) 3.00
Evidence for a prostate cancer susceptibility locus on the X chromosome. Nat Genet (1998) 2.90
Commitment to erythroid differentiation by friend erythroleukemia cells: a stochastic analysis. Cell (1976) 2.88
Determination of L1 retrotransposition kinetics in cultured cells. Nucleic Acids Res (2000) 2.84
A new retrotransposable human L1 element from the LRE2 locus on chromosome 1q produces a chimaeric insertion. Nat Genet (1994) 2.68
Improved detection of the sickle mutation by DNA analysis: application to prenatal diagnosis. N Engl J Med (1982) 2.64
Diagnosis of sickle cell anemia and beta-thalassemia with enzymatically amplified DNA and nonradioactive allele-specific oligonucleotide probes. N Engl J Med (1988) 2.64
Transduction of 3'-flanking sequences is common in L1 retrotransposition. Hum Mol Genet (2000) 2.57
Screening for psychosis in the general population with a self-report interview. J Nerv Ment Dis (1991) 2.56
Automated high resolution optical mapping using arrayed, fluid-fixed DNA molecules. Proc Natl Acad Sci U S A (1998) 2.50
Exclusion criteria of DSM-III. A study of co-occurrence of hierarchy-free syndromes. Arch Gen Psychiatry (1984) 2.50
Recurrent mutations in haemophilia A give evidence for CpG mutation hotspots. Nature (1987) 2.49
Mice lacking the myotonic dystrophy protein kinase develop a late onset progressive myopathy. Nat Genet (1996) 2.46
Deletion of the beta-globin structure gene in hereditary persistence of foetal haemoglobin. Nature (1975) 2.45
Quantitative deficiency of chain-specific globin messenger ribonucleic acids in the thalassemia syndromes. Proc Natl Acad Sci U S A (1973) 2.40
Two patients with cystic fibrosis, nonsense mutations in each cystic fibrosis gene, and mild pulmonary disease. N Engl J Med (1990) 2.37
A fine-structure deletion map of human chromosome 11p: analysis of J1 series hybrids. Somat Cell Mol Genet (1989) 2.29
The relationship of obsessive-compulsive disorder to possible spectrum disorders: results from a family study. Biol Psychiatry (2000) 2.29
Evidence for multiple origins of the beta E-globin gene in Southeast Asia. Proc Natl Acad Sci U S A (1982) 2.24
A novel active L1 retrotransposon subfamily in the mouse. Genome Res (2001) 2.21
Expression of the Wilms' tumor gene WT1 in the murine urogenital system. Genes Dev (1991) 2.20
Quantification of the close association between DNA haplotypes and specific beta-thalassaemia mutations in Mediterraneans. Nature (1984) 2.18
Full-length human L1 insertions retain the capacity for high frequency retrotransposition in cultured cells. Hum Mol Genet (1999) 2.15
Twin priming: a proposed mechanism for the creation of inversions in L1 retrotransposition. Genome Res (2001) 2.14
Absence of messenger RNA and gene DNA for beta-globin chains in hereditary persistence of fetal hemoglobin. Cell (1976) 2.10
DNA polymorphism and molecular pathology of the human globin gene clusters. Hum Genet (1985) 2.09
Meta-analysis of 32 genome-wide linkage studies of schizophrenia. Mol Psychiatry (2008) 2.07
Prenatal diagnosis using DNA polymorphisms. Report on 95 pregnancies at risk for sickle-cell disease or beta-thalassemia. N Engl J Med (1983) 2.06
Cloning and characterization of a second member of the mouse mdr gene family. Mol Cell Biol (1988) 2.06
Molecular characterization of seven beta-thalassemia mutations in Asian Indians. EMBO J (1984) 2.04
MLL is fused to CBP, a histone acetyltransferase, in therapy-related acute myeloid leukemia with a t(11;16)(q23;p13.3). Proc Natl Acad Sci U S A (1997) 2.01
Origin of the beta S-globin gene in blacks: the contribution of recurrent mutation or gene conversion or both. Proc Natl Acad Sci U S A (1984) 2.00
An actively retrotransposing, novel subfamily of mouse L1 elements. EMBO J (1998) 1.99
Abnormal RNA processing due to the exon mutation of beta E-globin gene. Nature (1982) 1.98
Direct detection of the common Mediterranean beta-thalassemia gene with synthetic DNA probes. An alternative approach for prenatal diagnosis. J Clin Invest (1983) 1.95
Nonsense and missense mutations in hemophilia A: estimate of the relative mutation rate at CG dinucleotides. Am J Hum Genet (1988) 1.93
beta-Thalassemia in Chinese: use of in vivo RNA analysis and oligonucleotide hybridization in systematic characterization of molecular defects. Proc Natl Acad Sci U S A (1984) 1.92
Hemophilia A. Detection of molecular defects and of carriers by DNA analysis. N Engl J Med (1985) 1.91
Stability of globin mRNA in terminally differentiating murine erythroleukemia cells. Cell (1981) 1.87
Genetic fine-structure mapping in human chromosome 11 by use of repetitive DNA sequences. Proc Natl Acad Sci U S A (1982) 1.83
Analysis of DNA polymorphism haplotypes linked to the cystic fibrosis locus in North American black and Caucasian families supports the existence of multiple mutations of the cystic fibrosis gene. Am J Hum Genet (1989) 1.81
beta-Thalassemia in American Blacks: novel mutations in the "TATA" box and an acceptor splice site. Proc Natl Acad Sci U S A (1984) 1.81
Mobile elements and the human genome. Nat Rev Genet (2000) 1.79
Thalassemia due to a mutation in the cleavage-polyadenylation signal of the human beta-globin gene. EMBO J (1985) 1.79
Induction of erythroid differentiation in vitro by purines and purine analogues. Cell (1976) 1.76
Two additional potential retrotransposons isolated from a human L1 subfamily that contains an active retrotransposable element. Proc Natl Acad Sci U S A (1993) 1.76
Molecular heterogeneity of inherited antithrombin III deficiency. N Engl J Med (1983) 1.75
Tay-Sachs screening: motives for participating and knowledge of genetics and probability. Am J Hum Genet (1976) 1.74