Published in Brain Res on April 10, 2010
Cell-type-based analysis of microRNA profiles in the mouse brain. Neuron (2012) 1.85
Deficiency of Dgcr8, a gene disrupted by the 22q11.2 microdeletion, results in altered short-term plasticity in the prefrontal cortex. Proc Natl Acad Sci U S A (2011) 1.65
Let-7, mir-98 and mir-183 as biomarkers for cancer and schizophrenia [corrected]. PLoS One (2015) 1.48
Experimental validation of candidate schizophrenia gene ZNF804A as target for hsa-miR-137. Schizophr Res (2012) 1.32
Exprtarget: an integrative approach to predicting human microRNA targets. PLoS One (2010) 1.31
Derepression of a neuronal inhibitor due to miRNA dysregulation in a schizophrenia-related microdeletion. Cell (2013) 1.19
Converging miRNA functions in diverse brain disorders: a case for miR-124 and miR-126. Exp Neurol (2011) 1.04
MicroRNA dysregulation in neuropsychiatric disorders and cognitive dysfunction. Neurobiol Dis (2012) 1.02
Brain derived neurotrophic factor (BDNF) expression is regulated by microRNAs miR-26a and miR-26b allele-specific binding. PLoS One (2011) 1.01
Dysregulation of miR-34a links neuronal development to genetic risk factors for bipolar disorder. Mol Psychiatry (2015) 0.99
The pattern of cortical dysfunction in a mouse model of a schizophrenia-related microdeletion. J Neurosci (2013) 0.97
MicroRNAs as the cause of schizophrenia in 22q11.2 deletion carriers, and possible implications for idiopathic disease: a mini-review. Front Mol Neurosci (2013) 0.93
A genome-wide integrative study of microRNAs in human liver. BMC Genomics (2013) 0.92
Converging evidence implicates the abnormal microRNA system in schizophrenia. Schizophr Bull (2014) 0.91
Genomic and epigenomic instability, fragile sites, schizophrenia and autism. Curr Genomics (2010) 0.89
22q11.2 deletion syndrome. Nat Rev Dis Prim (2015) 0.87
Genome-wide analysis implicates microRNAs and their target genes in the development of bipolar disorder. Transl Psychiatry (2015) 0.87
miR-137: a new player in schizophrenia. Int J Mol Sci (2014) 0.87
Comprehensive neurocognitive endophenotyping strategies for mouse models of genetic disorders. Prog Neurobiol (2012) 0.86
Transcriptome profiling of human hippocampus dentate gyrus granule cells in mental illness. Transl Psychiatry (2014) 0.85
Whole-Genome Sequencing Suggests Schizophrenia Risk Mechanisms in Humans with 22q11.2 Deletion Syndrome. G3 (Bethesda) (2015) 0.85
microRNAs That Promote or Inhibit Memory Formation in Drosophila melanogaster. Genetics (2015) 0.83
Specification of neural cell fate and regulation of neural stem cell proliferation by microRNAs. Am J Stem Cells (2012) 0.82
Association of a miRNA-137 polymorphism with schizophrenia in a Southern Chinese Han population. Biomed Res Int (2014) 0.82
MicroRNA-137 Inhibits EFNB2 Expression Affected by a Genetic Variant and Is Expressed Aberrantly in Peripheral Blood of Schizophrenia Patients. EBioMedicine (2016) 0.81
Characterizing autism spectrum disorders by key biochemical pathways. Front Neurosci (2015) 0.80
Potential molecular and cellular mechanism of psychotropic drugs. Clin Psychopharmacol Neurosci (2014) 0.79
Assessing the impact of copy number variants on miRNA genes in autism by Monte Carlo simulation. PLoS One (2014) 0.79
Investigation of the involvement of MIR185 and its target genes in the development of schizophrenia. J Psychiatry Neurosci (2014) 0.79
Epigenetic Mechanisms in Developmental Alcohol-Induced Neurobehavioral Deficits. Brain Sci (2016) 0.77
MicroRNA-181 promotes synaptogenesis and attenuates axonal outgrowth in cortical neurons. Cell Mol Life Sci (2016) 0.77
System-based proteomic and metabonomic analysis of the Df(16)A(+/-) mouse identifies potential miR-185 targets and molecular pathway alterations. Mol Psychiatry (2016) 0.77
Incorporating Information of microRNAs into Pathway Analysis in a Genome-Wide Association Study of Bipolar Disorder. Front Genet (2012) 0.76
Turing Revisited: Decoding the microRNA Messages in Brain Extracellular Vesicles for Early Detection of Neurodevelopmental Disorders. Curr Environ Health Rep (2016) 0.75
Developmental inhibition of miR-iab8-3p disrupts mushroom body neuron structure and adult learning ability. Dev Biol (2016) 0.75
Fluoxetine Increases the Expression of miR-572 and miR-663a in Human Neuroblastoma Cell Lines. PLoS One (2016) 0.75
Loss-of-function mutation in Mirta22/Emc10 rescues specific schizophrenia-related phenotypes in a mouse model of the 22q11.2 deletion. Proc Natl Acad Sci U S A (2017) 0.75
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell (1993) 64.62
Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature (2005) 48.95
Identification of tissue-specific microRNAs from mouse. Curr Biol (2002) 34.55
A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA. Science (2001) 31.33
Strong association of de novo copy number mutations with autism. Science (2007) 27.84
Argonaute2 is the catalytic engine of mammalian RNAi. Science (2004) 22.86
Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2. Nat Genet (1999) 22.84
Rare chromosomal deletions and duplications increase risk of schizophrenia. Nature (2008) 20.31
Large recurrent microdeletions associated with schizophrenia. Nature (2008) 20.25
Association between microdeletion and microduplication at 16p11.2 and autism. N Engl J Med (2008) 19.71
MicroRNA biogenesis: coordinated cropping and dicing. Nat Rev Mol Cell Biol (2005) 18.94
Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome. Cell (1991) 17.00
Structural variation of chromosomes in autism spectrum disorder. Am J Hum Genet (2008) 15.51
Mapping autism risk loci using genetic linkage and chromosomal rearrangements. Nat Genet (2007) 14.05
Autism as a strongly genetic disorder: evidence from a British twin study. Psychol Med (1995) 12.70
MicroRNAs regulate brain morphogenesis in zebrafish. Science (2005) 11.16
Extensive post-transcriptional regulation of microRNAs and its implications for cancer. Genes Dev (2006) 11.04
Strong association of de novo copy number mutations with sporadic schizophrenia. Nat Genet (2008) 10.19
A brain-specific microRNA regulates dendritic spine development. Nature (2006) 10.18
Autism genome-wide copy number variation reveals ubiquitin and neuronal genes. Nature (2009) 9.47
DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal. Nat Genet (2007) 9.25
Characterization of Dicer-deficient murine embryonic stem cells. Proc Natl Acad Sci U S A (2005) 8.35
A MicroRNA feedback circuit in midbrain dopamine neurons. Science (2007) 8.33
Sequence variants in SLITRK1 are associated with Tourette's syndrome. Science (2005) 8.20
The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing. Mol Cell (2007) 7.99
A progressive syndrome of autism, dementia, ataxia, and loss of purposeful hand use in girls: Rett's syndrome: report of 35 cases. Ann Neurol (1983) 6.80
Post-transcriptional regulation of microRNA expression. RNA (2006) 6.76
Recurrent 16p11.2 microdeletions in autism. Hum Mol Genet (2007) 6.75
A cAMP-response element binding protein-induced microRNA regulates neuronal morphogenesis. Proc Natl Acad Sci U S A (2005) 6.61
Altered synaptic plasticity in a mouse model of fragile X mental retardation. Proc Natl Acad Sci U S A (2002) 6.45
Fragile X-related protein and VIG associate with the RNA interference machinery. Genes Dev (2002) 6.43
A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins. Genes Dev (2002) 6.10
Reciprocal actions of REST and a microRNA promote neuronal identity. Proc Natl Acad Sci U S A (2006) 5.78
Schizophrenia susceptibility associated with interstitial deletions of chromosome 22q11. Proc Natl Acad Sci U S A (1995) 5.62
Infantile autism: a genetic study of 21 twin pairs. J Child Psychol Psychiatry (1977) 5.55
High rates of schizophrenia in adults with velo-cardio-facial syndrome. Arch Gen Psychiatry (1999) 5.54
miR-124 regulates adult neurogenesis in the subventricular zone stem cell niche. Nat Neurosci (2009) 5.27
Gene regulation by transcription factors and microRNAs. Science (2008) 5.07
The genetics of autism. Pediatrics (2004) 4.93
Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway. Nat Neurosci (2004) 4.69
The FMR-1 protein is cytoplasmic, most abundant in neurons and appears normal in carriers of a fragile X premutation. Nat Genet (1993) 4.57
Tethering of human Ago proteins to mRNA mimics the miRNA-mediated repression of protein synthesis. RNA (2004) 4.50
Cerebellar neurodegeneration in the absence of microRNAs. J Exp Med (2007) 4.48
Drosophila fragile X-related gene regulates the MAP1B homolog Futsch to control synaptic structure and function. Cell (2001) 4.21
A twin study of autism in Denmark, Finland, Iceland, Norway and Sweden. J Child Psychol Psychiatry (1989) 4.04
An activity-regulated microRNA controls dendritic plasticity by down-regulating p250GAP. Proc Natl Acad Sci U S A (2008) 3.98
Regulation of synaptic structure and function by FMRP-associated microRNAs miR-125b and miR-132. Neuron (2010) 3.96
Microdeletion/duplication at 15q13.2q13.3 among individuals with features of autism and other neuropsychiatric disorders. J Med Genet (2008) 3.87
Occurrence of neuropathological changes and dementia of Alzheimer's disease in Down's syndrome. Ann Neurol (1985) 3.83
Homeostatic regulation of MeCP2 expression by a CREB-induced microRNA. Nat Neurosci (2007) 3.81
Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model. Nat Genet (2008) 3.76
Posttranscriptional crossregulation between Drosha and DGCR8. Cell (2009) 3.54
Degradation of microRNAs by a family of exoribonucleases in Arabidopsis. Science (2008) 3.46
Genome-wide analyses of exonic copy number variants in a family-based study point to novel autism susceptibility genes. PLoS Genet (2009) 3.42
Noncoding RNAs in the mammalian central nervous system. Annu Rev Neurosci (2006) 3.41
Conditional loss of Dicer disrupts cellular and tissue morphogenesis in the cortex and hippocampus. J Neurosci (2008) 3.33
Characterization of small RNAs in Aplysia reveals a role for miR-124 in constraining synaptic plasticity through CREB. Neuron (2009) 3.27
microRNA expression in the prefrontal cortex of individuals with schizophrenia and schizoaffective disorder. Genome Biol (2007) 3.26
Prevalence of fragile X syndrome. Am J Med Genet (1996) 3.19
The fragile X syndrome protein represses activity-dependent translation through CYFIP1, a new 4E-BP. Cell (2008) 3.10
The pathophysiology of fragile x syndrome. Annu Rev Genomics Hum Genet (2007) 2.85
Detection of mammalian microRNA expression by in situ hybridization with RNA oligonucleotides. Dev Dyn (2006) 2.83
Molecular mapping of twenty-four features of Down syndrome on chromosome 21. Eur J Hum Genet (1993) 2.73
microRNAs at the synapse. Nat Rev Neurosci (2009) 2.66
Mef2-mediated transcription of the miR379-410 cluster regulates activity-dependent dendritogenesis by fine-tuning Pumilio2 protein levels. EMBO J (2009) 2.65
Novel submicroscopic chromosomal abnormalities detected in autism spectrum disorder. Biol Psychiatry (2008) 2.60
A direct role for FMRP in activity-dependent dendritic mRNA transport links filopodial-spine morphogenesis to fragile X syndrome. Dev Cell (2008) 2.51
Heterogeneous dysregulation of microRNAs across the autism spectrum. Neurogenetics (2008) 2.50
Comparative sequence analysis reveals an intricate network among REST, CREB and miRNA in mediating neuronal gene expression. Genome Biol (2006) 2.49
MicroRNA miR-124 regulates neurite outgrowth during neuronal differentiation. Exp Cell Res (2008) 2.46
Developmental roles and molecular characterization of a Drosophila homologue of Arabidopsis Argonaute1, the founder of a novel gene superfamily. Genes Cells (2001) 2.43
Dysregulation of miRNA 181b in the temporal cortex in schizophrenia. Hum Mol Genet (2008) 2.33
MicroRNAs potentiate neural development. Neuron (2009) 2.25
Schizophrenia is associated with an increase in cortical microRNA biogenesis. Mol Psychiatry (2009) 2.16
Selective dendritic alterations in the cortex of Rett syndrome. J Neuropathol Exp Neurol (1995) 2.15
The behavioral spectrum of Gilles de la Tourette syndrome. J Neuropsychiatry Clin Neurosci (2009) 2.14
Expression of microRNAs and their precursors in synaptic fractions of adult mouse forebrain. J Neurochem (2008) 2.07
MicroRNA-219 modulates NMDA receptor-mediated neurobehavioral dysfunction. Proc Natl Acad Sci U S A (2009) 2.00
Rett syndrome: confirmation of X-linked dominant inheritance, and localization of the gene to Xq28. Am J Hum Genet (1998) 1.98
Retracted Human chromosome 21-derived miRNAs are overexpressed in down syndrome brains and hearts. Biochem Biophys Res Commun (2008) 1.91
Sequential strategy to identify a susceptibility gene for schizophrenia: report of potential linkage on chromosome 22q12-q13.1: Part 1. Am J Med Genet (1994) 1.86
Brain expressed microRNAs implicated in schizophrenia etiology. PLoS One (2007) 1.85
Overrepresentation of rare variants in a specific ethnic group may confuse interpretation of association analyses. Hum Mol Genet (2006) 1.84
Excess protein synthesis in Drosophila fragile X mutants impairs long-term memory. Nat Neurosci (2008) 1.83
Evidence for selective microRNAs and their effectors as common long-term targets for the actions of mood stabilizers. Neuropsychopharmacology (2008) 1.79
Fragile X mental retardation protein induces synapse loss through acute postsynaptic translational regulation. J Neurosci (2007) 1.78
Molecular determinants of dysregulated GABAergic gene expression in the prefrontal cortex of subjects with schizophrenia. Biol Psychiatry (2009) 1.71
The neurocognitive phenotype of the 22q11.2 deletion syndrome: selective deficit in visual-spatial memory. J Clin Exp Neuropsychol (2001) 1.70
Post-transcriptional control of DGCR8 expression by the Microprocessor. RNA (2009) 1.67
Genome-wide identification of targets of the drosha-pasha/DGCR8 complex. RNA (2009) 1.59
Retracted Chromosome 21-derived microRNAs provide an etiological basis for aberrant protein expression in human Down syndrome brains. J Biol Chem (2009) 1.53
The genetics of Tourette syndrome: a review. J Psychosom Res (2009) 1.46
The steady-state level of the nervous-system-specific microRNA-124a is regulated by dFMR1 in Drosophila. J Neurosci (2008) 1.38
Synaptic ionotropic glutamate receptors and plasticity are developmentally altered in the CA1 field of Fmr1 knockout mice. J Physiol (2008) 1.29
MeCP2-dependent repression of an imprinted miR-184 released by depolarization. Hum Mol Genet (2008) 1.29
Examination of the SLITRK1 gene in Caucasian patients with Tourette syndrome. Acta Neurol Scand (2006) 1.26
Neuropsychological characteristics of children with the 22q11 Deletion Syndrome: a descriptive analysis. Child Neuropsychol (2005) 1.25
Excess of twins among affected sibling pairs with autism: implications for the etiology of autism. Am J Hum Genet (2001) 1.25
Molecular-clinical correlations in males with an expanded FMR1 mutation. Am J Med Genet (1996) 1.24
Functional SLITRK1 var321, varCDfs and SLC6A4 G56A variants and susceptibility to obsessive-compulsive disorder. Mol Psychiatry (2006) 1.23
Strong association of de novo copy number mutations with sporadic schizophrenia. Nat Genet (2008) 10.19
Convergent evidence for impaired AKT1-GSK3beta signaling in schizophrenia. Nat Genet (2004) 4.71
Exome sequencing supports a de novo mutational paradigm for schizophrenia. Nat Genet (2011) 4.67
Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model. Nat Genet (2008) 3.76
Magnitude and distribution of linkage disequilibrium in population isolates and implications for genome-wide association studies. Nat Genet (2006) 3.54
Duplications of the neuropeptide receptor gene VIPR2 confer significant risk for schizophrenia. Nature (2011) 3.51
Spontaneous neural activity is required for the establishment and maintenance of the olfactory sensory map. Neuron (2004) 3.50
De novo gene mutations highlight patterns of genetic and neural complexity in schizophrenia. Nat Genet (2012) 3.49
High frequencies of de novo CNVs in bipolar disorder and schizophrenia. Neuron (2011) 3.08
Impaired hippocampal-prefrontal synchrony in a genetic mouse model of schizophrenia. Nature (2010) 2.92
Evidence that the gene encoding ZDHHC8 contributes to the risk of schizophrenia. Nat Genet (2004) 2.77
Modeling madness in mice: one piece at a time. Neuron (2006) 2.60
22q11.2 microdeletions: linking DNA structural variation to brain dysfunction and schizophrenia. Nat Rev Neurosci (2010) 2.54
A mutation in mouse Disc1 that models a schizophrenia risk allele leads to specific alterations in neuronal architecture and cognition. Proc Natl Acad Sci U S A (2008) 2.37
Disc1 is mutated in the 129S6/SvEv strain and modulates working memory in mice. Proc Natl Acad Sci U S A (2006) 2.32
Palmitoylation-dependent neurodevelopmental deficits in a mouse model of 22q11 microdeletion. Nat Neurosci (2008) 1.92
Genetic variation at the 22q11 PRODH2/DGCR6 locus presents an unusual pattern and increases susceptibility to schizophrenia. Proc Natl Acad Sci U S A (2002) 1.92
Transcriptional and behavioral interaction between 22q11.2 orthologs modulates schizophrenia-related phenotypes in mice. Nat Neurosci (2005) 1.91
Site-specific role of catechol-O-methyltransferase in dopamine overflow within prefrontal cortex and dorsal striatum. J Neurosci (2007) 1.75
The molecular genetics of the 22q11-associated schizophrenia. Brain Res Mol Brain Res (2004) 1.74
Elucidating the genetic architecture of familial schizophrenia using rare copy number variant and linkage scans. Proc Natl Acad Sci U S A (2009) 1.73
Deficiency of Dgcr8, a gene disrupted by the 22q11.2 microdeletion, results in altered short-term plasticity in the prefrontal cortex. Proc Natl Acad Sci U S A (2011) 1.65
Genetic variation in the 22q11 locus and susceptibility to schizophrenia. Proc Natl Acad Sci U S A (2002) 1.60
Evidence for association of schizophrenia with genetic variation in the 8p21.3 gene, PPP3CC, encoding the calcineurin gamma subunit. Proc Natl Acad Sci U S A (2003) 1.54
Brain catecholamine metabolism in catechol-O-methyltransferase (COMT)-deficient mice. Eur J Neurosci (2002) 1.51
Akt1 deficiency affects neuronal morphology and predisposes to abnormalities in prefrontal cortex functioning. Proc Natl Acad Sci U S A (2006) 1.44
Genetic modulation of BDNF signaling affects the outcome of axonal competition in vivo. Curr Biol (2007) 1.40
S-nitrosylation and S-palmitoylation reciprocally regulate synaptic targeting of PSD-95. Neuron (2011) 1.35
Diverse types of genetic variation converge on functional gene networks involved in schizophrenia. Nat Neurosci (2012) 1.34
Genomewide scan in families with schizophrenia from the founder population of Afrikaners reveals evidence for linkage and uniparental disomy on chromosome 1. Am J Hum Genet (2004) 1.34
Sequence variants of the brain-derived neurotrophic factor (BDNF) gene are strongly associated with obsessive-compulsive disorder. Am J Hum Genet (2003) 1.32
Neuropsychological characteristics of children with the 22q11 Deletion Syndrome: a descriptive analysis. Child Neuropsychol (2005) 1.25
Lower prepulse inhibition in children with the 22q11 deletion syndrome. Am J Psychiatry (2005) 1.25
Effect of dopamine uptake inhibition on brain catecholamine levels and locomotion in catechol-O-methyltransferase-disrupted mice. J Pharmacol Exp Ther (2002) 1.19
Derepression of a neuronal inhibitor due to miRNA dysregulation in a schizophrenia-related microdeletion. Cell (2013) 1.19
The best of times, the worst of times for psychiatric disease. Nat Neurosci (2012) 1.18
Quantitative role of COMT in dopamine clearance in the prefrontal cortex of freely moving mice. J Neurochem (2010) 1.17
The 22q11.2 microdeletion: fifteen years of insights into the genetic and neural complexity of psychiatric disorders. Int J Dev Neurosci (2010) 1.16
The genetic architecture of schizophrenia: new mutations and emerging paradigms. Annu Rev Med (2011) 1.14
Networks of attention in children with the 22q11 deletion syndrome. Dev Neuropsychol (2004) 1.13
Scan statistic-based analysis of exome sequencing data identifies FAN1 at 15q13.3 as a susceptibility gene for schizophrenia and autism. Proc Natl Acad Sci U S A (2013) 1.13
Cognition in mouse models of schizophrenia susceptibility genes. Schizophr Bull (2009) 1.11
Genetic and cognitive windows into circuit mechanisms of psychiatric disease. Trends Neurosci (2011) 1.10
Altered axonal targeting and short-term plasticity in the hippocampus of Disc1 mutant mice. Proc Natl Acad Sci U S A (2011) 1.09
MicroRNA dysregulation in neuropsychiatric disorders and cognitive dysfunction. Neurobiol Dis (2012) 1.02
Resistance to salt-induced hypertension in catechol-O-methyltransferase-gene-disrupted mice. J Hypertens (2003) 1.01
Phenotypic characterization and genealogical tracing in an Afrikaner schizophrenia database. Am J Med Genet B Neuropsychiatr Genet (2004) 1.00
The pattern of cortical dysfunction in a mouse model of a schizophrenia-related microdeletion. J Neurosci (2013) 0.97
A signaling pathway AKTing up in schizophrenia. J Clin Invest (2008) 0.96
Nogo Receptor 1 (RTN4R) as a candidate gene for schizophrenia: analysis using human and mouse genetic approaches. PLoS One (2007) 0.96
Decreased phosphorylation of NMDA receptor type 1 at serine 897 in brains of patients with Schizophrenia. J Neurosci (2004) 0.95
Development of animal models for schizophrenia. Dis Model Mech (2010) 0.93
Chronic adolescent exposure to Δ-9-tetrahydrocannabinol in COMT mutant mice: impact on psychosis-related and other phenotypes. Neuropsychopharmacology (2010) 0.93
D-amphetamine responses in catechol-O-methyltransferase (COMT) disrupted mice. Psychopharmacology (Berl) (2003) 0.92
Extended intermarker linkage disequilibrium in the Afrikaners. Genome Res (2002) 0.91
The Drosophila zinc finger transcription factor CF2 is a myogenic marker downstream of MEF2 during muscle development. Mech Dev (2002) 0.91
Molecules, signaling, and schizophrenia. Curr Top Behav Neurosci (2010) 0.91
C9ORF72 repeat expansions not detected in a group of patients with schizophrenia. Neurobiol Aging (2012) 0.89
Neuromotor deficits in children with the 22q11 deletion syndrome. Mov Disord (2006) 0.87
Evidence for altered hippocampal function in a mouse model of the human 22q11.2 microdeletion. Mol Cell Neurosci (2011) 0.86