Published in J Bacteriol on June 01, 1994
Biogenesis, architecture, and function of bacterial type IV secretion systems. Annu Rev Microbiol (2005) 6.16
The versatile bacterial type IV secretion systems. Nat Rev Microbiol (2003) 4.98
Definition of a bacterial type IV secretion pathway for a DNA substrate. Science (2004) 3.76
Biological diversity of prokaryotic type IV secretion systems. Microbiol Mol Biol Rev (2009) 3.72
Conjugative plasmid transfer in gram-positive bacteria. Microbiol Mol Biol Rev (2003) 3.33
Agrobacterium tumefaciens T-complex transport apparatus: a paradigm for a new family of multifunctional transporters in eubacteria. J Bacteriol (1997) 3.31
Trans-kingdom T-DNA transfer from Agrobacterium tumefaciens to Saccharomyces cerevisiae. EMBO J (1995) 3.23
Involvement of a plasmid in virulence of Campylobacter jejuni 81-176. Infect Immun (2000) 3.11
The bases of crown gall tumorigenesis. J Bacteriol (2000) 2.81
Adaptation of a conjugal transfer system for the export of pathogenic macromolecules. Trends Microbiol (1996) 2.74
The structural biology of type IV secretion systems. Nat Rev Microbiol (2009) 2.54
Identification of genes required for chronic persistence of Brucella abortus in mice. Infect Immun (2000) 2.31
The Agrobacterium tumefaciens VirB7 lipoprotein is required for stabilization of VirB proteins during assembly of the T-complex transport apparatus. J Bacteriol (1996) 2.30
Characterization of mycobacterial virulence genes through genetic interaction mapping. Proc Natl Acad Sci U S A (2006) 2.29
Transfer of T-DNA from Agrobacterium to the plant cell. Plant Physiol (1995) 2.24
Energetic components VirD4, VirB11 and VirB4 mediate early DNA transfer reactions required for bacterial type IV secretion. Mol Microbiol (2004) 2.11
Intermolecular disulfide bonds stabilize VirB7 homodimers and VirB7/VirB9 heterodimers during biogenesis of the Agrobacterium tumefaciens T-complex transport apparatus. Proc Natl Acad Sci U S A (1996) 2.08
Peptide linkage mapping of the Agrobacterium tumefaciens vir-encoded type IV secretion system reveals protein subassemblies. Proc Natl Acad Sci U S A (2002) 2.06
The Agrobacterium T-DNA transport pore proteins VirB8, VirB9, and VirB10 interact with one another. J Bacteriol (2000) 2.02
Interactions between VirB9 and VirB10 membrane proteins involved in movement of DNA from Agrobacterium tumefaciens into plant cells. J Bacteriol (1997) 1.99
The Agrobacterium tumefaciens virB7 gene product, a proposed component of the T-complex transport apparatus, is a membrane-associated lipoprotein exposed at the periplasmic surface. J Bacteriol (1996) 1.97
Peptidoglycan as a barrier to transenvelope transport. J Bacteriol (1996) 1.96
Agrobacterium tumefaciens VirB7 and VirB9 form a disulfide-linked protein complex. Proc Natl Acad Sci U S A (1996) 1.96
Agrobacterium VirB10, an ATP energy sensor required for type IV secretion. Proc Natl Acad Sci U S A (2004) 1.96
VirE2, a type IV secretion substrate, interacts with the VirD4 transfer protein at cell poles of Agrobacterium tumefaciens. Mol Microbiol (2003) 1.94
Vir proteins stabilize VirB5 and mediate its association with the T pilus of Agrobacterium tumefaciens. J Bacteriol (1999) 1.93
Dimerization of the Agrobacterium tumefaciens VirB4 ATPase and the effect of ATP-binding cassette mutations on the assembly and function of the T-DNA transporter. Mol Microbiol (1999) 1.82
Inhibition of VirB-mediated transfer of diverse substrates from Agrobacterium tumefaciens by the IncQ plasmid RSF1010. J Bacteriol (1995) 1.79
Type IV secretion: the Agrobacterium VirB/D4 and related conjugation systems. Biochim Biophys Acta (2004) 1.78
Identification of VceA and VceC, two members of the VjbR regulon that are translocated into macrophages by the Brucella type IV secretion system. Mol Microbiol (2008) 1.76
Agrobacterium-plant cell DNA transport: have virulence proteins, will travel. Plant Cell (1996) 1.75
VirB1, a component of the T-complex transfer machinery of Agrobacterium tumefaciens, is processed to a C-terminal secreted product, VirB1. J Bacteriol (1997) 1.72
Characterization of membrane and protein interaction determinants of the Agrobacterium tumefaciens VirB11 ATPase. J Bacteriol (1997) 1.71
A family of lysozyme-like virulence factors in bacterial pathogens of plants and animals. Proc Natl Acad Sci U S A (1996) 1.70
Temperature affects the T-DNA transfer machinery of Agrobacterium tumefaciens. J Bacteriol (1996) 1.68
Genetic and environmental factors affecting T-pilin export and T-pilus biogenesis in relation to flagellation of Agrobacterium tumefaciens. J Bacteriol (2000) 1.67
The lipoprotein VirB7 interacts with VirB9 in the membranes of Agrobacterium tumefaciens. J Bacteriol (1997) 1.66
The G alpha i homologue gna-1 controls multiple differentiation pathways in Neurospora crassa. Mol Biol Cell (1996) 1.65
Spatial location and requirements for the assembly of the Agrobacterium tumefaciens type IV secretion apparatus. Proc Natl Acad Sci U S A (2005) 1.64
Agrobacterium tumefaciens VirB6 protein participates in formation of VirB7 and VirB9 complexes required for type IV secretion. J Bacteriol (2003) 1.58
Gene 19 of plasmid R1 is required for both efficient conjugative DNA transfer and bacteriophage R17 infection. J Bacteriol (1995) 1.57
Role of Agrobacterium VirB11 ATPase in T-pilus assembly and substrate selection. J Bacteriol (2001) 1.56
The product of the virB4 gene of Agrobacterium tumefaciens promotes accumulation of VirB3 protein. J Bacteriol (1994) 1.55
N-linked protein glycosylation is required for full competence in Campylobacter jejuni 81-176. J Bacteriol (2004) 1.54
Two novel type III-secreted proteins of Xanthomonas campestris pv. vesicatoria are encoded within the hrp pathogenicity island. J Bacteriol (2002) 1.53
The VirB4 ATPase of Agrobacterium tumefaciens is a cytoplasmic membrane protein exposed at the periplasmic surface. J Bacteriol (1997) 1.50
VirB7 lipoprotein is exocellular and associates with the Agrobacterium tumefaciens T pilus. J Bacteriol (2001) 1.45
VirB6 is required for stabilization of VirB5 and VirB3 and formation of VirB7 homodimers in Agrobacterium tumefaciens. J Bacteriol (2000) 1.40
Mutagenesis of the Agrobacterium VirE2 single-stranded DNA-binding protein identifies regions required for self-association and interaction with VirE1 and a permissive site for hybrid protein construction. J Bacteriol (1999) 1.39
Interactions of VirB9, -10, and -11 with the membrane fraction of Agrobacterium tumefaciens: solubility studies provide evidence for tight associations. J Bacteriol (1995) 1.39
Agrobacterium tumefaciens VirB6 domains direct the ordered export of a DNA substrate through a type IV secretion System. J Mol Biol (2004) 1.39
Differential requirements for VirB1 and VirB2 during Brucella abortus infection. Infect Immun (2004) 1.33
Functional and topological characterization of novel components of the comB DNA transformation competence system in Helicobacter pylori. J Bacteriol (2006) 1.31
A novel cytology-based, two-hybrid screen for bacteria applied to protein-protein interaction studies of a type IV secretion system. J Bacteriol (2002) 1.30
Self-assembly of the Agrobacterium tumefaciens VirB11 traffic ATPase. J Bacteriol (2000) 1.29
Suppression of mutant phenotypes of the Agrobacterium tumefaciens VirB11 ATPase by overproduction of VirB proteins. J Bacteriol (1997) 1.28
Ti plasmid conjugation is independent of vir: reconstitution of the tra functions from pTiC58 as a binary system. J Bacteriol (1997) 1.28
Delineation of the interaction domains of Agrobacterium tumefaciens VirB7 and VirB9 by use of the yeast two-hybrid assay. J Bacteriol (1997) 1.27
An anomalous type IV secretion system in Rickettsia is evolutionarily conserved. PLoS One (2009) 1.26
Role of Agrobacterium virB genes in transfer of T complexes and RSF1010. J Bacteriol (1998) 1.24
Agrobacterium tumefaciens VirB9, an outer-membrane-associated component of a type IV secretion system, regulates substrate selection and T-pilus biogenesis. J Bacteriol (2005) 1.24
TraC of IncN plasmid pKM101 associates with membranes and extracellular high-molecular-weight structures in Escherichia coli. J Bacteriol (1999) 1.23
The expanding bacterial type IV secretion lexicon. Res Microbiol (2013) 1.22
Agrobacterium VirB10 domain requirements for type IV secretion and T pilus biogenesis. Mol Microbiol (2008) 1.21
Mechanism and structure of the bacterial type IV secretion systems. Biochim Biophys Acta (2014) 1.20
Agrobacterium tumefaciens twin-arginine-dependent translocation is important for virulence, flagellation, and chemotaxis but not type IV secretion. J Bacteriol (2003) 1.20
The N- and C-terminal portions of the Agrobacterium VirB1 protein independently enhance tumorigenesis. J Bacteriol (2000) 1.19
The Ti plasmid increases the efficiency of Agrobacterium tumefaciens as a recipient in virB-mediated conjugal transfer of an IncQ plasmid. Proc Natl Acad Sci U S A (1998) 1.18
Phylogenomics reveals a diverse Rickettsiales type IV secretion system. Infect Immun (2010) 1.17
Elevated temperature differentially affects virulence, VirB protein accumulation, and T-pilus formation in different Agrobacterium tumefaciens and Agrobacterium vitis strains. J Bacteriol (2001) 1.17
The conjugal intermediate of plasmid RSF1010 inhibits Agrobacterium tumefaciens virulence and VirB-dependent export of VirE2. J Bacteriol (1998) 1.14
Evolution of conjugation and type IV secretion systems. Mol Biol Evol (2012) 1.14
Evidence for VirB4-mediated dislocation of membrane-integrated VirB2 pilin during biogenesis of the Agrobacterium VirB/VirD4 type IV secretion system. J Bacteriol (2010) 1.13
VirB3 to VirB6 and VirB8 to VirB11, but not VirB7, are essential for mediating persistence of Brucella in the reticuloendothelial system. J Bacteriol (2008) 1.13
VirB1* promotes T-pilus formation in the vir-Type IV secretion system of Agrobacterium tumefaciens. J Bacteriol (2007) 1.13
Functional subsets of the virB type IV transport complex proteins involved in the capacity of Agrobacterium tumefaciens to serve as a recipient in virB-mediated conjugal transfer of plasmid RSF1010. J Bacteriol (2003) 1.12
Stability of the Agrobacterium tumefaciens VirB10 protein is modulated by growth temperature and periplasmic osmoadaption. J Bacteriol (1998) 1.11
The chvH locus of Agrobacterium encodes a homologue of an elongation factor involved in protein synthesis. J Bacteriol (2001) 1.10
Functional and mutational analysis of p19, a DNA transfer protein with muramidase activity. J Bacteriol (2001) 1.10
Activities of virE1 and the VirE1 secretion chaperone in export of the multifunctional VirE2 effector via an Agrobacterium type IV secretion pathway. J Bacteriol (2001) 1.09
Essential components of the Ti plasmid trb system, a type IV macromolecular transporter. J Bacteriol (1999) 1.05
Anaplasma marginale type IV secretion system proteins VirB2, VirB7, VirB11, and VirD4 are immunogenic components of a protective bacterial membrane vaccine. Infect Immun (2010) 1.04
Recent advances in the structural and molecular biology of type IV secretion systems. Curr Opin Struct Biol (2014) 1.02
VirB1 orthologs from Brucella suis and pKM101 complement defects of the lytic transglycosylase required for efficient type IV secretion from Agrobacterium tumefaciens. J Bacteriol (2004) 1.00
Genetic and functional characterization of the type IV secretion system in Wolbachia. J Bacteriol (2008) 0.99
Agrobacterium tumefaciens oncogenic suppressors inhibit T-DNA and VirE2 protein substrate binding to the VirD4 coupling protein. Mol Microbiol (2005) 0.99
Agrobacterium tumefaciens type IV secretion protein VirB3 is an inner membrane protein and requires VirB4, VirB7, and VirB8 for stabilization. J Bacteriol (2010) 0.99
Reexamining the role of the accessory plasmid pAtC58 in the virulence of Agrobacterium tumefaciens strain C58. Plant Physiol (2003) 0.98
Functional analysis of the Agrobacterium tumefaciens T-DNA transport pore protein VirB8. J Bacteriol (2001) 0.98
Key components of the eight classes of type IV secretion systems involved in bacterial conjugation or protein secretion. Nucleic Acids Res (2014) 0.97
DNA substrate-induced activation of the Agrobacterium VirB/VirD4 type IV secretion system. J Bacteriol (2013) 0.94
The octopine-type Ti plasmid pTiA6 of Agrobacterium tumefaciens contains a gene homologous to the chromosomal virulence gene acvB. J Bacteriol (1995) 0.94
Interaction between protein subunits of the type IV secretion system of Bartonella henselae. J Bacteriol (2004) 0.93
An Agrobacterium VirB10 mutation conferring a type IV secretion system gating defect. J Bacteriol (2011) 0.92
The dimer interface of Agrobacterium tumefaciens VirB8 is important for type IV secretion system function, stability, and association of VirB2 with the core complex. J Bacteriol (2011) 0.89
Extracellular VirB5 enhances T-DNA transfer from Agrobacterium to the host plant. PLoS One (2011) 0.88
Structure of the type IV secretion system in different strains of Anaplasma phagocytophilum. BMC Genomics (2012) 0.88
Detection of conjugation related type four secretion machinery in Aeromonas culicicola. PLoS One (2006) 0.86
The Brucella suis type IV secretion system assembles in the cell envelope of the heterologous host Agrobacterium tumefaciens and increases IncQ plasmid pLS1 recipient competence. Infect Immun (2006) 0.86
A putative transmembrane leucine zipper of agrobacterium VirB10 is essential for t-pilus biogenesis but not type IV secretion. J Bacteriol (2013) 0.85
The complete general secretory pathway in gram-negative bacteria. Microbiol Rev (1993) 16.84
Lessons from an evolving rRNA: 16S and 23S rRNA structures from a comparative perspective. Microbiol Rev (1994) 9.74
The genetic and transcriptional organization of the vir region of the A6 Ti plasmid of Agrobacterium tumefaciens. EMBO J (1986) 7.90
Common components in the assembly of type 4 fimbriae, DNA transfer systems, filamentous phage and protein-secretion apparatus: a general system for the formation of surface-associated protein complexes. Mol Microbiol (1993) 4.74
Two-way chemical signaling in Agrobacterium-plant interactions. Microbiol Rev (1992) 4.37
Molecular characterization of an operon required for pertussis toxin secretion. Proc Natl Acad Sci U S A (1993) 4.12
Sugars induce the Agrobacterium virulence genes through a periplasmic binding protein and a transmembrane signal protein. Proc Natl Acad Sci U S A (1990) 3.48
Characterization of the virB operon from an Agrobacterium tumefaciens Ti plasmid. J Biol Chem (1988) 3.40
The Agrobacterium tumefaciens virE2 gene product is a single-stranded-DNA-binding protein that associates with T-DNA. J Bacteriol (1988) 3.21
Agrobacterium tumefaciens and the susceptible plant cell: a novel adaptation of extracellular recognition and DNA conjugation. Cell (1986) 3.20
Sequence similarities between the RP4 Tra2 and the Ti VirB region strongly support the conjugation model for T-DNA transfer. J Biol Chem (1992) 3.15
Conjugative Transfer by the Virulence System of Agrobacterium tumefaciens. Science (1992) 3.07
Conjugal transfer system of the IncN plasmid pKM101. J Bacteriol (1985) 3.03
Illegitimate recombination in plants: a model for T-DNA integration. Genes Dev (1991) 2.73
Controlled expression of the transcriptional activator gene virG in Agrobacterium tumefaciens by using the Escherichia coli lac promoter. J Bacteriol (1991) 2.62
Structural basis of pilus subunit recognition by the PapD chaperone. Science (1993) 2.30
A gene required for transfer of T-DNA to plants encodes an ATPase with autophosphorylating activity. Proc Natl Acad Sci U S A (1989) 2.25
The regulatory VirG protein specifically binds to a cis-acting regulatory sequence involved in transcriptional activation of Agrobacterium tumefaciens virulence genes. J Bacteriol (1990) 2.24
The virB operon of Agrobacterium tumefaciens pTiC58 encodes 11 open reading frames. Mol Gen Genet (1990) 2.14
Analysis of the complete nucleotide sequence of the Agrobacterium tumefaciens virB operon. Nucleic Acids Res (1988) 2.13
Subcellular localization of seven VirB proteins of Agrobacterium tumefaciens: implications for the formation of a T-DNA transport structure. J Bacteriol (1993) 2.10
The Agrobacterium tumefaciens virB4 gene product is an essential virulence protein requiring an intact nucleoside triphosphate-binding domain. J Bacteriol (1993) 2.09
Membrane location of the Ti plasmid VirB proteins involved in the biosynthesis of a pilin-like conjugative structure on Agrobacterium tumefaciens. FEMS Microbiol Lett (1993) 2.06
Control of expression of Agrobacterium vir genes by synergistic actions of phenolic signal molecules and monosaccharides. Proc Natl Acad Sci U S A (1990) 1.98
Identification of a virB10 protein aggregate in the inner membrane of Agrobacterium tumefaciens. J Bacteriol (1990) 1.94
Characterization of Agrobacterium tumefaciens virulence proteins induced by the plant factor acetosyringone. J Mol Biol (1987) 1.90
Pertussis toxin export requires accessory genes located downstream from the pertussis toxin operon. Mol Microbiol (1993) 1.89
The mating pair formation system of plasmid RP4 defined by RSF1010 mobilization and donor-specific phage propagation. J Bacteriol (1993) 1.89
Analysis of Agrobacterium tumefaciens virulence mutants in leaf discs. Proc Natl Acad Sci U S A (1986) 1.87
Complementation analysis of Agrobacterium tumefaciens Ti plasmid virB genes by use of a vir promoter expression vector: virB9, virB10, and virB11 are essential virulence genes. J Bacteriol (1990) 1.83
A nuclear localization signal and the C-terminal omega sequence in the Agrobacterium tumefaciens VirD2 endonuclease are important for tumor formation. Proc Natl Acad Sci U S A (1992) 1.80
Transport of nucleic acids through membrane channels: snaking through small holes. Annu Rev Microbiol (1993) 1.69
Correction: characterization of the virB operon from Agrobacterium tumefaciens Ti plasmid. J Biol Chem (1990) 1.60
Activity of the Agrobacterium T-DNA transfer machinery is affected by virB gene products. Proc Natl Acad Sci U S A (1991) 1.57
An inner-membrane-associated virulence protein essential for T-DNA transfer from Agrobacterium tumefaciens to plants exhibits ATPase activity and similarities to conjugative transfer genes. Mol Microbiol (1994) 1.52
The essential virulence protein VirB8 localizes to the inner membrane of Agrobacterium tumefaciens. J Bacteriol (1994) 1.51
The chromosomal response regulatory gene chvI of Agrobacterium tumefaciens complements an Escherichia coli phoB mutation and is required for virulence. J Bacteriol (1993) 1.48
Characterization of the virB operon of an Agrobacterium tumefaciens Ti plasmid: nucleotide sequence and protein analysis. Mol Microbiol (1990) 1.40
vir genes influence conjugal transfer of the Ti plasmid of Agrobacterium tumefaciens. J Bacteriol (1990) 1.38
Construction and characterization of Tn5virB, a transposon that generates nonpolar mutations, and its use to define virB8 as an essential virulence gene in Agrobacterium tumefaciens. J Bacteriol (1993) 1.31
The virB operon of the Agrobacterium tumefaciens virulence regulon has sequence similarities to B, C and D open reading frames downstream of the pertussis toxin-operon and to the DNA transfer-operons of broad-host-range conjugative plasmids. Nucleic Acids Res (1993) 1.22
Synthesis of F pilin. J Bacteriol (1993) 1.09
Virulence genes promote conjugative transfer of the Ti plasmid between Agrobacterium strains. J Bacteriol (1990) 1.05
Construction, expression, and localization of a CycA::PhoA fusion protein in Rhodobacter sphaeroides and Escherichia coli. J Bacteriol (1989) 1.01
Adaptation of a conjugal transfer system for the export of pathogenic macromolecules. Trends Microbiol (1996) 2.74
Two conjugation systems associated with Streptococcus faecalis plasmid pCF10: identification of a conjugative transposon that transfers between S. faecalis and Bacillus subtilis. J Bacteriol (1987) 2.61
The Agrobacterium tumefaciens VirB7 lipoprotein is required for stabilization of VirB proteins during assembly of the T-complex transport apparatus. J Bacteriol (1996) 2.30
The regulatory VirG protein specifically binds to a cis-acting regulatory sequence involved in transcriptional activation of Agrobacterium tumefaciens virulence genes. J Bacteriol (1990) 2.24
Identification of regions of the Streptococcus faecalis plasmid pCF-10 that encode antibiotic resistance and pheromone response functions. Plasmid (1986) 2.19
The Agrobacterium tumefaciens virB4 gene product is an essential virulence protein requiring an intact nucleoside triphosphate-binding domain. J Bacteriol (1993) 2.09
Intermolecular disulfide bonds stabilize VirB7 homodimers and VirB7/VirB9 heterodimers during biogenesis of the Agrobacterium tumefaciens T-complex transport apparatus. Proc Natl Acad Sci U S A (1996) 2.08
The Agrobacterium tumefaciens virB7 gene product, a proposed component of the T-complex transport apparatus, is a membrane-associated lipoprotein exposed at the periplasmic surface. J Bacteriol (1996) 1.97
Complementation analysis of Agrobacterium tumefaciens Ti plasmid virB genes by use of a vir promoter expression vector: virB9, virB10, and virB11 are essential virulence genes. J Bacteriol (1990) 1.83
Dimerization of the Agrobacterium tumefaciens VirB4 ATPase and the effect of ATP-binding cassette mutations on the assembly and function of the T-DNA transporter. Mol Microbiol (1999) 1.82
Characterization of membrane and protein interaction determinants of the Agrobacterium tumefaciens VirB11 ATPase. J Bacteriol (1997) 1.71
Role of Agrobacterium VirB11 ATPase in T-pilus assembly and substrate selection. J Bacteriol (2001) 1.56
The VirB4 ATPase of Agrobacterium tumefaciens is a cytoplasmic membrane protein exposed at the periplasmic surface. J Bacteriol (1997) 1.50
VirB7 lipoprotein is exocellular and associates with the Agrobacterium tumefaciens T pilus. J Bacteriol (2001) 1.45
Mutagenesis of the Agrobacterium VirE2 single-stranded DNA-binding protein identifies regions required for self-association and interaction with VirE1 and a permissive site for hybrid protein construction. J Bacteriol (1999) 1.39
Self-assembly of the Agrobacterium tumefaciens VirB11 traffic ATPase. J Bacteriol (2000) 1.29
Suppression of mutant phenotypes of the Agrobacterium tumefaciens VirB11 ATPase by overproduction of VirB proteins. J Bacteriol (1997) 1.28
Activities of virE1 and the VirE1 secretion chaperone in export of the multifunctional VirE2 effector via an Agrobacterium type IV secretion pathway. J Bacteriol (2001) 1.09
Effects of tylosin feeding on the antibiotic resistance of selected gram-positive bacteria in pigs. Am J Vet Res (1983) 0.96
Antibiotic selection pressure resulting in multiple antibiotic resistance and localization of resistance determinants to conjugative plasmids in streptococci. J Infect Dis (1984) 0.94
Plasmids in Bacillus popilliae. J Invertebr Pathol (1990) 0.83
The cag pathogenicity island: mechanistic insights. Trends Microbiol (1997) 0.81