Formation of functional peptide complexes of class II major histocompatibility complex proteins from subunits produced in Escherichia coli.

PubWeight™: 1.13‹?› | Rank: Top 10%

🔗 View Article (PMC 47768)

Published in Proc Natl Acad Sci U S A on November 01, 1993

Authors

J D Altman1, P A Reay, M M Davis

Author Affiliations

1: Department of Microbiology and Immunology, Stanford University, CA 94305-5428.

Articles citing this

Critical role for alpha/beta and gamma interferons in persistence of lymphocytic choriomeningitis virus by clonal exhaustion of cytotoxic T cells. J Virol (2001) 2.69

Viral escape by selection of cytotoxic T cell-resistant variants in influenza A virus pneumonia. J Exp Med (2000) 1.65

Class II major histocompatibility complex tetramer staining: progress, problems, and prospects. Immunology (2008) 1.47

Thermodynamics of T cell receptor binding to peptide-MHC: evidence for a general mechanism of molecular scanning. Proc Natl Acad Sci U S A (1999) 1.47

Class II-restricted T cell receptor engineered in vitro for higher affinity retains peptide specificity and function. Proc Natl Acad Sci U S A (2005) 1.46

Critical role for perforin-, Fas/FasL-, and TNFR1-mediated cytotoxic pathways in down-regulation of antigen-specific T cells during persistent viral infection. J Virol (2002) 1.39

Interrogating the repertoire: broadening the scope of peptide-MHC multimer analysis. Nat Rev Immunol (2011) 1.32

Quantitation of CD8(+) T-lymphocyte responses to multiple epitopes from simian virus 40 (SV40) large T antigen in C57BL/6 mice immunized with SV40, SV40 T-antigen-transformed cells, or vaccinia virus recombinants expressing full-length T antigen or epitope minigenes. J Virol (2000) 1.31

Empty class II major histocompatibility complex created by peptide photolysis establishes the role of DM in peptide association. J Biol Chem (2007) 1.16

Peptide-MHC heterodimers show that thymic positive selection requires a more restricted set of self-peptides than negative selection. J Exp Med (2010) 1.12

Expression and crystallization of the complex of HLA-DR2 (DRA, DRB1*1501) and an immunodominant peptide of human myelin basic protein. Proc Natl Acad Sci U S A (1998) 1.09

Functional recombinant MHC class II molecules and high-throughput peptide-binding assays. Immunome Res (2009) 1.03

Photocrosslinkable pMHC monomers stain T cells specifically and cause ligand-bound TCRs to be 'preferentially' transported to the cSMAC. Nat Immunol (2012) 0.95

High-affinity T cell receptor differentiates cognate peptide-MHC and altered peptide ligands with distinct kinetics and thermodynamics. Mol Immunol (2010) 0.87

The ability to rearrange dual TCRs enhances positive selection, leading to increased Allo- and Autoreactive T cell repertoires. J Immunol (2014) 0.85

Cell surface display of functional human MHC class II proteins: yeast display versus insect cell display. Protein Eng Des Sel (2011) 0.80

Tetramers reveal IL-17-secreting CD4+ T cells that are specific for U1-70 in lupus and mixed connective tissue disease. Proc Natl Acad Sci U S A (2015) 0.80

Generation of human alloantigen-specific T cells from peripheral blood. J Vis Exp (2014) 0.75

Articles cited by this

Use of T7 RNA polymerase to direct expression of cloned genes. Methods Enzymol (1990) 61.47

Principles that govern the folding of protein chains. Science (1973) 23.40

Structure of the human class I histocompatibility antigen, HLA-A2. Nature (1987) 14.54

Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1. Nature (1993) 8.75

Continuous proliferation of murine antigen-specific helper T lymphocytes in culture. J Exp Med (1979) 7.20

Empty MHC class I molecules come out in the cold. Nature (1990) 5.53

HLA-A2-peptide complexes: refolding and crystallization of molecules expressed in Escherichia coli and complexed with single antigenic peptides. Proc Natl Acad Sci U S A (1992) 5.02

Structure, function, and diversity of class I major histocompatibility complex molecules. Annu Rev Biochem (1990) 4.02

Emerging principles for the recognition of peptide antigens by MHC class I molecules. Science (1992) 3.64

The three-dimensional structure of HLA-B27 at 2.1 A resolution suggests a general mechanism for tight peptide binding to MHC. Cell (1992) 3.27

Low affinity interaction of peptide-MHC complexes with T cell receptors. Science (1991) 2.89

The human class II MHC protein HLA-DR1 assembles as empty alpha beta heterodimers in the absence of antigenic peptide. Cell (1992) 2.79

Crystal structure of the major histocompatibility complex class I H-2Kb molecule containing a single viral peptide: implications for peptide binding and T-cell receptor recognition. Proc Natl Acad Sci U S A (1992) 2.16

Molecular components of T-cell recognition. Annu Rev Immunol (1992) 1.96

Expression of a class II major histocompatibility complex (MHC) heterodimer in a lipid-linked form with enhanced peptide/soluble MHC complex formation at low pH. J Exp Med (1991) 1.92

Renaturation, purification and characterization of recombinant Fab-fragments produced in Escherichia coli. Biotechnology (N Y) (1991) 1.88

Empty and peptide-containing conformers of class I major histocompatibility complex molecules expressed in Drosophila melanogaster cells. Proc Natl Acad Sci U S A (1992) 1.79

Reconstitution by MHC-restricted peptides of HLA-A2 heavy chain with beta 2-microglobulin, in vitro. Nature (1991) 1.55

pH dependence and exchange of high and low responder peptides binding to a class II MHC molecule. EMBO J (1992) 1.36

Purification of HLA-linked B lymphocyte alloantigens in immunologically active form by preparative sodium dodecyl sulfate-gel electrophoresis and studies on their subunit association. J Biol Chem (1977) 1.24

Enhanced binding of peptide antigen to purified class II major histocompatibility glycoproteins at acidic pH. J Exp Med (1991) 1.19

How MHC class II molecules work: peptide-dependent completion of protein folding. Immunol Today (1992) 1.14

Refolding and reassembly of separate alpha and beta chains of class II molecules of the major histocompatibility complex leads to increased peptide-binding capacity. Proc Natl Acad Sci U S A (1990) 1.08

Structurally interdependent and independent regions of allelic polymorphism in class II MHC molecules. Implications for Ia function and evolution. J Immunol (1990) 1.04

P-cell stimulating factor: characterization, action on multiple lineages of bone-marrow-derived cells and role in oncogenesis. Immunol Rev (1983) 1.00

Detergent-assisted refolding of guanidinium chloride-denatured rhodanese. The effect of lauryl maltoside. J Biol Chem (1986) 0.95

Two-dimensional nuclear magnetic resonance analysis of a labeled peptide bound to a class II major histocompatibility complex molecule. J Mol Biol (1993) 0.88

Intracellular expression of BPTI fusion proteins and single column cleavage/affinity purification by chymotrypsin. Protein Eng (1991) 0.88

Articles by these authors

Phenotypic analysis of antigen-specific T lymphocytes. Science (1996) 24.26

The immunological synapse: a molecular machine controlling T cell activation. Science (1999) 17.41

Polymerase chain reaction with single-sided specificity: analysis of T cell receptor delta chain. Science (1989) 9.01

Isolation of cDNA clones encoding T cell-specific membrane-associated proteins. Nature (1984) 8.89

The presence of interleukin 4 during in vitro priming determines the lymphokine-producing potential of CD4+ T cells from T cell receptor transgenic mice. J Exp Med (1992) 7.80

Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients. Nat Med (1999) 6.09

Sequence relationships between putative T-cell receptor polypeptides and immunoglobulins. Nature (1984) 6.08

Blimp-1, a novel zinc finger-containing protein that can drive the maturation of B lymphocytes into immunoglobulin-secreting cells. Cell (1994) 4.60

The immunological synapse. Annu Rev Immunol (2001) 4.45

Somatic recombination in a murine T-cell receptor gene. Nature (1984) 4.21

Genomic organization and sequence of T-cell receptor beta-chain constant- and joining-region genes. Nature (1984) 4.15

Mapping T-cell receptor-peptide contacts by variant peptide immunization of single-chain transgenics. Nature (1992) 4.01

An immunoglobulin heavy-chain gene is formed by at least two recombinational events. Nature (1980) 3.99

A kinetic basis for T cell receptor repertoire selection during an immune response. Immunity (1999) 3.88

A receptor/cytoskeletal movement triggered by costimulation during T cell activation. Science (1998) 3.76

DNA sequences mediating class switching in alpha-immunoglobulins. Science (1980) 3.70

Diversity in the CDR3 region of V(H) is sufficient for most antibody specificities. Immunity (2000) 3.49

Cell-type-specific cDNA probes and the murine I region: the localization and orientation of Ad alpha. Proc Natl Acad Sci U S A (1984) 3.43

The adult T-cell receptor delta-chain is diverse and distinct from that of fetal thymocytes. Nature (1988) 3.43

Antigen-specific development of primary and memory T cells in vivo. Science (1995) 3.41

Structural gene sets active in embryos and adult tissues of the sea urchin. Cell (1976) 3.38

CDR3 length in antigen-specific immune receptors. J Exp Med (1994) 3.35

Isolation of high avidity melanoma-reactive CTL from heterogeneous populations using peptide-MHC tetramers. J Immunol (1999) 3.33

Melanocyte destruction after antigen-specific immunotherapy of melanoma: direct evidence of t cell-mediated vitiligo. J Exp Med (2000) 3.32

Differential clustering of CD4 and CD3zeta during T cell recognition. Science (2000) 3.30

Quantitative analysis of hepatitis C virus-specific CD8(+) T cells in peripheral blood and liver using peptide-MHC tetramers. Proc Natl Acad Sci U S A (1999) 3.30

Antigen/MHC-specific T cells are preferentially exported from the thymus in the presence of their MHC ligand. Cell (1989) 3.29

A third type of murine T-cell receptor gene. Nature (1984) 3.24

A human T cell-specific molecule is a member of a new gene family. J Immunol (1988) 3.21

Immunoglobulin heavy chain gene organization in mice: analysis of a myeloma genomic clone containing variable and alpha constant regions. Proc Natl Acad Sci U S A (1979) 3.19

A new T-cell receptor gene located within the alpha locus and expressed early in T-cell differentiation. Nature (1987) 3.08

Kinetics of T-cell receptor binding to peptide/I-Ek complexes: correlation of the dissociation rate with T-cell responsiveness. Proc Natl Acad Sci U S A (1994) 3.07

Low affinity interaction of peptide-MHC complexes with T cell receptors. Science (1991) 2.89

Frequency of class I HLA-restricted anti-HIV CD8+ T cells in individuals receiving highly active antiretroviral therapy (HAART). J Immunol (1999) 2.89

T-cell receptor delta gene rearrangements in early thymocytes. Nature (1988) 2.88

Evidence that specific T lymphocytes may participate in the elimination of chronic myelogenous leukemia. Nat Med (2000) 2.78

Structure, expression and divergence of T-cell receptor beta-chain variable regions. Nature (1984) 2.71

A TCR binds to antagonist ligands with lower affinities and faster dissociation rates than to agonists. Immunity (1996) 2.69

Visualizing the dynamics of T cell activation: intracellular adhesion molecule 1 migrates rapidly to the T cell/B cell interface and acts to sustain calcium levels. Proc Natl Acad Sci U S A (1998) 2.69

The nature of major histocompatibility complex recognition by gamma delta T cells. Cell (1994) 2.64

Resting and anergic B cells are defective in CD28-dependent costimulation of naive CD4+ T cells. J Exp Med (1994) 2.61

Expression of T cell antigen receptor heterodimers in a lipid-linked form. Science (1990) 2.56

Initiation of signal transduction through the T cell receptor requires the multivalent engagement of peptide/MHC ligands [corrected]. Immunity (1998) 2.52

CD95 (Fas)-dependent elimination of self-reactive B cells upon interaction with CD4+ T cells. Nature (1995) 2.45

Kinetic discrimination in T-cell activation. Proc Natl Acad Sci U S A (1996) 2.17

Use of global amino acid replacements to define the requirements for MHC binding and T cell recognition of moth cytochrome c (93-103). J Immunol (1994) 2.15

Getting heavier, younger: trajectories of obesity over the life course. Int J Obes (Lond) (2009) 2.09

Identification of self through two-dimensional chemistry and synapses. Annu Rev Cell Dev Biol (2001) 1.99

Localization of a T-cell receptor diversity-region element. Nature (1984) 1.96

Molecular components of T-cell recognition. Annu Rev Immunol (1992) 1.96

Regulating the retention of T-cell receptor alpha chain variants within the endoplasmic reticulum: Ca(2+)-dependent association with BiP. J Cell Biol (1991) 1.93

Not without my permission: parents' willingness to permit use of newborn screening samples for research. Public Health Genomics (2009) 1.92

Expression of a class II major histocompatibility complex (MHC) heterodimer in a lipid-linked form with enhanced peptide/soluble MHC complex formation at low pH. J Exp Med (1991) 1.92

Altered peptide ligand vaccination with Flt3 ligand expanded dendritic cells for tumor immunotherapy. Proc Natl Acad Sci U S A (2001) 1.85

Identification and sequence of a fourth human T cell antigen receptor chain. Nature (1988) 1.81

Molecular genetics of the T cell-receptor beta chain. Annu Rev Immunol (1985) 1.76

Induction of rapid T cell activation and tolerance by systemic presentation of an orally administered antigen. Immunity (1998) 1.74

T cell assays and MIATA: the essential minimum for maximum impact. Immunity (2012) 1.74

Rearrangements of genes for the antigen receptor on T cells as markers of lineage and clonality in human lymphoid neoplasms. N Engl J Med (1985) 1.65

Altered T cell receptor ligands trigger a subset of early T cell signals. Immunity (1996) 1.64

Experience with juvenile polyps in North American children: the need for pancolonoscopy. Am J Gastroenterol (2001) 1.61

Ligand-specific oligomerization of T-cell receptor molecules. Nature (1997) 1.58

The effects of MHC gene dosage and allelic variation on T cell receptor selection. Cell (1990) 1.58

Formation of a highly peptide-receptive state of class II MHC. Immunity (1998) 1.58

Expression of genes of the T-cell antigen receptor complex in precursor thymocytes. Nature (1985) 1.57

A murine T cell receptor gene complex: isolation, structure and rearrangement. Immunol Rev (1984) 1.56

T-lymphocyte-antigen interactions in transplant rejection. N Engl J Med (1990) 1.55

A range of CD4 T cell tolerance: partial inactivation to organ-specific antigen allows nondestructive thyroiditis or insulitis. Immunity (1997) 1.55

Protection against lethal influenza with neuraminidase. Virology (1988) 1.51

Kinetics and extent of T cell activation as measured with the calcium signal. J Exp Med (1997) 1.51

GROUP MEDICINE. Am J Public Health (N Y) (1919) 1.50

Nuclear location of all three influenza polymerase proteins and a nuclear signal in polymerase PB2. EMBO J (1986) 1.48

Thermodynamics of T cell receptor binding to peptide-MHC: evidence for a general mechanism of molecular scanning. Proc Natl Acad Sci U S A (1999) 1.47

Immunoglobulin class switching: developmentally regulated DNA rearrangements during differentiation. Cell (1980) 1.46

A PR1-human leukocyte antigen-A2 tetramer can be used to isolate low-frequency cytotoxic T lymphocytes from healthy donors that selectively lyse chronic myelogenous leukemia. Cancer Res (1999) 1.45

Phenotypic differences between alpha beta versus beta T-cell receptor transgenic mice undergoing negative selection. Nature (1989) 1.44

Helper and killer T cells do not express B cell immunoglobulin joining and constant region gene segments. J Exp Med (1980) 1.42

C. M. A. DEPARTMENT OF PUBLIC RELATIONS: DO CORPORATIONS PRACTICE MEDICINE? Cal West Med (1932) 1.41

Attributes of gammadelta intraepithelial lymphocytes as suggested by their transcriptional profile. Proc Natl Acad Sci U S A (2001) 1.38

pH dependence and exchange of high and low responder peptides binding to a class II MHC molecule. EMBO J (1992) 1.36

Minimal information about T cell assays: the process of reaching the community of T cell immunologists in cancer and beyond. Cancer Immunol Immunother (2010) 1.36

A kinetic window constricts the T cell receptor repertoire in the thymus. Immunity (2001) 1.32

Determination of the relationship between T cell responsiveness and the number of MHC-peptide complexes using specific monoclonal antibodies. J Immunol (2000) 1.32

T cell receptor interaction with peptide/major histocompatibility complex (MHC) and superantigen/MHC ligands is dominated by antigen. J Exp Med (1993) 1.31

Activation and differentiation requirements of primary T cells in vitro. Proc Natl Acad Sci U S A (1993) 1.29

Transfer of putative complementarity-determining region loops of T cell receptor V domains confers toxin reactivity but not peptide/MHC specificity. J Immunol (1993) 1.24

The vav exchange factor is an essential regulator in actin-dependent receptor translocation to the lymphocyte-antigen-presenting cell interface. Proc Natl Acad Sci U S A (2000) 1.24

Differential effect of B lymphocyte-induced maturation protein (Blimp-1) expression on cell fate during B cell development. J Exp Med (1998) 1.23

Expression of T-cell receptor alpha-chain genes in transgenic mice. Mol Cell Biol (1988) 1.20

CD4 augments the response of a T cell to agonist but not to antagonist ligands. Immunity (1997) 1.19

Isolation of a cDNA clone corresponding to an X-linked gene family (XLR) closely linked to the murine immunodeficiency disorder xid. Nature (1985) 1.18

Secretion of a chimeric T-cell receptor-immunoglobulin protein. Proc Natl Acad Sci U S A (1987) 1.17

Murine T cell receptor beta chain is encoded on chromosome 6. J Exp Med (1984) 1.16

Kinetics of peptide binding to the class II MHC protein I-Ek. Biochemistry (2000) 1.14

The isolation and sequence of a novel gene from a human functional T cell line. J Exp Med (1987) 1.14