Reaction of proteasomes with peptidylchloromethanes and peptidyldiazomethanes.

PubWeight™: 0.86‹?›

🔗 View Article (PMC 1137740)

Published in Biochem J on December 15, 1993

Authors

P J Savory1, H Djaballah, H Angliker, E Shaw, A J Rivett

Author Affiliations

1: Department of Biochemistry, University of Leicester, U.K.

Articles cited by this

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem (1976) 903.81

Peptidyl diazomethyl ketones are specific inactivators of thiol proteinases. J Biol Chem (1981) 2.29

Proteasomes: multicatalytic proteinase complexes. Biochem J (1993) 2.08

The multicatalytic proteinase complex, a major extralysosomal proteolytic system. Biochemistry (1990) 2.07

Inactivation of trypsin-like enzymes with peptides of arginine chloromethyl ketone. Methods Enzymol (1981) 2.00

Cation-sensitive neutral endopeptidase: isolation and specificity of the bovine pituitary enzyme. J Neurochem (1980) 1.74

Purification of a liver alkaline protease which degrades oxidatively modified glutamine synthetase. Characterization as a high molecular weight cysteine proteinase. J Biol Chem (1985) 1.70

The multicatalytic proteinase of mammalian cells. Arch Biochem Biophys (1989) 1.66

The design of peptidyldiazomethane inhibitors to distinguish between the cysteine proteinases calpain II, cathepsin L and cathepsin B. Biochem J (1988) 1.60

A comparison of the behavior of chymotrypsin and cathepsin B towards peptidyl diazomethyl ketones. Biochem Biophys Res Commun (1979) 1.56

Purification and characterization of a multicatalytic high-molecular-mass proteinase from rat skeletal muscle. Biochem J (1985) 1.51

Cysteinyl proteinases and their selective inactivation. Adv Enzymol Relat Areas Mol Biol (1990) 1.43

Proteasomes: protein and gene structures. New Biol (1992) 1.39

Diazomethyl ketone substrate derivatives as active-site-directed inhibitors of thiol proteases. Papain. Biochemistry (1977) 1.30

The multicatalytic proteinase. Multiple proteolytic activities. J Biol Chem (1989) 1.26

Pituitary multicatalytic proteinase complex. Specificity of components and aspects of proteolytic activity. Biochemistry (1989) 1.17

Purification and characterization of a high molecular weight proteinase (macropain) from human erythrocytes. Biochim Biophys Acta (1986) 1.11

Regulation of the peptidylglutamyl-peptide hydrolyzing activity of the pituitary multicatalytic proteinase complex. Biochemistry (1991) 0.98

Peptidylglutamyl-peptide hydrolase activity of the multicatalytic proteinase complex: evidence for a new high-affinity site, analysis of cooperative kinetics, and the effect of manganese ions. Biochemistry (1992) 0.97

Synthesis and properties of Cbz-Phe-Arg-CHN2 (benzyloxycarbonylphenylalanylarginyldiazomethane) as a proteinase inhibitor. Biochem J (1988) 0.97

Use of serine-protease inhibitors as probes for the different proteolytic activities of the rat liver multicatalytic proteinase complex. Eur J Biochem (1992) 0.96

Properties of subunits of the multicatalytic proteinase complex revealed by the use of subunit-specific antibodies. Biochem J (1991) 0.94

Leupeptin-binding site(s) in the mammalian multicatalytic proteinase complex. Biochem J (1993) 0.91

Iodination of peptidyl chloromethyl ketones for protease affinity labels. Anal Biochem (1988) 0.91

The inactivation of the cysteinyl exopeptidases cathepsin H and C by affinity-labelling reagents. Biochem J (1989) 0.89

Multicatalytic, high-Mr endopeptidase from postmortem human brain. J Neurochem (1991) 0.88

A 3,4-dichloroisocoumarin-resistant component of the multicatalytic proteinase complex. Biochemistry (1992) 0.87

Peptidyldiazomethanes. A novel mechanism of interaction with prolyl endopeptidase. Biochem J (1992) 0.87

Characterization of the active site of human multicatalytic proteinase. Biochem J (1990) 0.85

Articles by these authors

Influenza virus hemagglutinin with multibasic cleavage site is activated by furin, a subtilisin-like endoprotease. EMBO J (1992) 5.05

p-Nitrophenyl-p'-guanidinobenzoate HCl: a new active site titrant for trypsin. Biochem Biophys Res Commun (1967) 4.79

A viral inhibitor of peptide transporters for antigen presentation. Nature (1995) 4.26

Inhibition of furin-mediated cleavage activation of HIV-1 glycoprotein gp160. Nature (1992) 4.16

5-methylcytosine-DNA glycosylase activity is present in a cloned G/T mismatch DNA glycosylase associated with the chicken embryo DNA demethylation complex. Proc Natl Acad Sci U S A (2000) 2.98

Molecular mechanism and species specificity of TAP inhibition by herpes simplex virus ICP47. EMBO J (1996) 2.64

Comparison of the esterase activities of trypsin, plasmin, and thrombin on guanidinobenzoate esters. Titration of the enzymes. Biochemistry (1969) 2.61

Selective chemical modification of proteins. Physiol Rev (1970) 2.50

Peptidyl diazomethyl ketones are specific inactivators of thiol proteinases. J Biol Chem (1981) 2.29

Rapid caspase-3 activation during apoptosis revealed using fluorescence-resonance energy transfer. EMBO Rep (2000) 2.12

D-Phe-Pro-ArgCH2C1-A selective affinity label for thrombin. Thromb Res (1979) 2.09

Processing of viral glycoproteins by the subtilisin-like endoprotease furin and its inhibition by specific peptidylchloroalkylketones. Biochimie (1994) 2.07

Inactivation of trypsin-like enzymes with peptides of arginine chloromethyl ketone. Methods Enzymol (1981) 2.00

Factors associated with complications and mortality in adult patients hospitalized for infectious cellulitis. Eur J Clin Microbiol Infect Dis (2003) 1.92

Degradation of proteasomes by lysosomes in rat liver. Eur J Biochem (1995) 1.90

A BIOCHEMICAL AND PHARMACOLOGICAL SUGGESTION ABOUT CERTAIN MENTAL DISORDERS. Proc Natl Acad Sci U S A (1954) 1.85

Population screening reduces mortality rate from aortic aneurysm in men. Br J Surg (2000) 1.79

Preferential degradation of the oxidatively modified form of glutamine synthetase by intracellular mammalian proteases. J Biol Chem (1985) 1.76

5-Methylcytosine DNA glycosylase activity is also present in the human MBD4 (G/T mismatch glycosylase) and in a related avian sequence. Nucleic Acids Res (2000) 1.71

Purification of a liver alkaline protease which degrades oxidatively modified glutamine synthetase. Characterization as a high molecular weight cysteine proteinase. J Biol Chem (1985) 1.70

Methods for measuring the three-dimensional structure of fish schools. Anim Behav (1965) 1.68

Chromatography of trypsin and its derivatives. Characterization of a new active form of bovine trypsin. J Biol Chem (1968) 1.66

The design of peptidyldiazomethane inhibitors to distinguish between the cysteine proteinases calpain II, cathepsin L and cathepsin B. Biochem J (1988) 1.60

Rapid interaction of cathepsin L by Z-Phe-PheCHN12 and Z-Phe-AlaCHN2. Biochem Biophys Res Commun (1981) 1.58

Thiobenzyl benzyloxycarbonyl-L-lysinate, substrate for a sensitive colorimetric assay for trypsin-like enzymes. Anal Biochem (1979) 1.57

Insomnia and the eye of the beholder: are there clinical markers of objective sleep disturbances among adults with and without insomnia complaints? J Consult Clin Psychol (2000) 1.57

A comparison of the behavior of chymotrypsin and cathepsin B towards peptidyl diazomethyl ketones. Biochem Biophys Res Commun (1979) 1.56

Subpopulations of proteasomes in rat liver nuclei, microsomes and cytosol. Biochem J (1996) 1.56

Regulatory circuits involved with pH-regulated gene expression in Salmonella typhimurium. Microbiology (1994) 1.55

The interaction of thrombin with fibrinogen. A structural basis for its specificity. Eur J Biochem (1992) 1.53

Sleep in the laboratory and sleep at home: comparisons of older insomniacs and normal sleepers. Sleep (1997) 1.51

The inhibition of macrophage protein turnover by a selective inhibitor of thiol proteinases. Biochem J (1980) 1.50

Photochemical Activities of Spinach Chloroplasts Following Treatment with the Detergent Triton X-100. Plant Physiol (1965) 1.44

Looking through the retrospectoscope in the era of evidence-based medicine. J Clin Oncol (1997) 1.43

Proteolytic cleavage of wild type and mutants of the F protein of human parainfluenza virus type 3 by two subtilisin-like endoproteases, furin and Kex2. J Virol (1994) 1.41

Affinity labelling of proteinases with tryptic specificity by peptides with C-terminal lysine chloromethyl ketone. Biochem J (1974) 1.37

A chicken embryo protein related to the mammalian DEAD box protein p68 is tightly associated with the highly purified protein-RNA complex of 5-MeC-DNA glycosylase. Nucleic Acids Res (1999) 1.33

Diazomethyl ketone substrate derivatives as active-site-directed inhibitors of thiol proteases. Papain. Biochemistry (1977) 1.30

Overexpression of 5-methylcytosine DNA glycosylase in human embryonic kidney cells EcR293 demethylates the promoter of a hormone-regulated reporter gene. Proc Natl Acad Sci U S A (2001) 1.28

Screening for abdominal aortic aneurysms in men. BMJ (2004) 1.21

Sleep in the laboratory and sleep at home II: comparisons of middle-aged insomnia sufferers and normal sleepers. Sleep (2001) 1.21

Inhibition of proteolytic activation of influenza virus hemagglutinin by specific peptidyl chloroalkyl ketones. Virology (1989) 1.18

Catalytic properties of 26 S and 20 S proteasomes and radiolabeling of MB1, LMP7, and C7 subunits associated with trypsin-like and chymotrypsin-like activities. J Biol Chem (1997) 1.18

Degradation of substituted phenylurea herbicides by Arthrobacter globiformis strain D47 and characterization of a plasmid-associated hydrolase gene, puhA. Appl Environ Microbiol (2001) 1.17

The synthesis of peptidylfluoromethanes and their properties as inhibitors of serine proteinases and cysteine proteinases. Biochem J (1986) 1.17

Synthesis of peptides of arginine chloromethyl ketone. Selective inactivation of human plasma kallikrein. Biochemistry (1978) 1.17

Covalent modification of proteins by mixed-function oxidation: recognition by intracellular proteases. Prog Clin Biol Res (1985) 1.16

Inactivation of cathepsin B by active site-directed disulfide exchange. Application in covalent affinity chromatography. J Biol Chem (1983) 1.16

An exploration of the primary specificity site of cathepsin B. Arch Biochem Biophys (1983) 1.15

Occupational sunlight exposure and melanoma in the U.S. Navy. Arch Environ Health (1991) 1.14

The reactivity of His-57 in chymotrypsin to alkylation. Arch Biochem Biophys (1971) 1.13

Novel, starch-like polysaccharides are synthesized by an unbound form of granule-bound starch synthase in glycogen-accumulating mutants of Chlamydomonas reinhardtii. Plant Physiol (1999) 1.13

Cofactor dependence of factor Xa incorporation into the prothrombinase complex. J Biol Chem (1981) 1.12

Active center differences between cathepsins L and B: the S1 binding region. FEBS Lett (1988) 1.12

Multicatalytic endopeptidase complex: proteasome. Methods Enzymol (1994) 1.12

Changes in proteasome localization during the cell cycle. Eur J Cell Biol (1994) 1.10

A single normal ultrasonographic scan at age 65 years rules out significant aneurysm disease for life in men. Br J Surg (2001) 1.10

Healthcare-associated, community-acquired and hospital-acquired bacteraemic urinary tract infections in hospitalized patients: a prospective multicentre cohort study in the era of antimicrobial resistance. Clin Microbiol Infect (2012) 1.09

A comparison of the mortality rate after elective repair of aortic aneurysms detected either by screening or incidentally. Eur J Vasc Endovasc Surg (2000) 1.09

The synthesis of inhibitors for processing proteinases and their action on the Kex2 proteinase of yeast. Biochem J (1993) 1.08

Phototherapy of jaundice in the newborn infant. II. Effect of various light intensities. J Pediatr (1972) 1.08

Inactivation of thiol proteases with peptidyl diazomethyl ketones. Methods Enzymol (1981) 1.08

Pseudotrypsin. A modified bovine trypsin produced by limited autodigestion. J Biol Chem (1969) 1.07

Inactivation of cathepsin B1 by diazomethyl ketones. Biochem Biophys Res Commun (1977) 1.07

Identification of the histidine residue at the active center of trypsin labelled by TLCK. Biochem Biophys Res Commun (1967) 1.07

LMP2+ proteasomes are required for the presentation of specific antigens to cytotoxic T lymphocytes. Curr Biol (1995) 1.06

Further observations on substrate-derived chloromethyl ketones that inactivate trypsin. Arch Biochem Biophys (1970) 1.05

Regulation of intracellular protein turnover: covalent modification as a mechanism of marking proteins for degradation. Curr Top Cell Regul (1986) 1.05

Cross-reactivity between B. burgdorferi and other spirochetes affects specificity of serotests for detection of antibodies to the Lyme disease agent in dogs. Vet Microbiol (1993) 1.04

Phosphorylation of proteasomes in mammalian cells. Identification of two phosphorylated subunits and the effect of phosphorylation on activity. Eur J Biochem (1996) 1.04

Combination antifungal therapy for cryptococcal meningitis. Postgrad Med J (1976) 1.04

Inactivation of prolyl endopeptidase by a peptidylchloromethane. Kinetics of inactivation and identification of sites of modification. Biochem J (1991) 1.03

A pre-existing protease is a common effector of thymocyte apoptosis mediated by diverse stimuli. FEBS Lett (1995) 1.03

Inhibition of matrix metalloproteinase 2 maturation and HT1080 invasiveness by a synthetic furin inhibitor. FEBS Lett (1998) 1.03

N-terminal sequence similarities between components of the multicatalytic proteinase complex. FEBS Lett (1990) 1.02

Phosphorylation of ATPase subunits of the 26S proteasome. FEBS Lett (1998) 1.02

The optomotor reaction of schooling carangid fishes. Anim Behav (1965) 1.02

Special needs of ritually circumcised women patients. J Obstet Gynecol Neonatal Nurs (1991) 1.01

The essentiality of histidine in the catalytic action of subtilisin. Covalent modification by a specific reagent. J Biol Chem (1968) 1.01

Synthesis and properties of peptidyl derivatives of arginylfluoromethanes. Biochem J (1988) 0.99

The impact of individual human immunodeficiency virus type 1 protease mutations on drug susceptibility is highly influenced by complex interactions with the background protease sequence. J Virol (2009) 0.98

Synthesis and properties of Cbz-Phe-Arg-CHN2 (benzyloxycarbonylphenylalanylarginyldiazomethane) as a proteinase inhibitor. Biochem J (1988) 0.97

Peptidylglutamyl-peptide hydrolase activity of the multicatalytic proteinase complex: evidence for a new high-affinity site, analysis of cooperative kinetics, and the effect of manganese ions. Biochemistry (1992) 0.97

Incidence of leukemia in occupations with potential electromagnetic field exposure in United States Navy personnel. Am J Epidemiol (1990) 0.97

Association of immunoproteasomes with the endoplasmic reticulum. Biochem J (2000) 0.96

Use of serine-protease inhibitors as probes for the different proteolytic activities of the rat liver multicatalytic proteinase complex. Eur J Biochem (1992) 0.96

Characterization of structural determinants and molecular mechanisms involved in pro-stromelysin-3 activation by 4-aminophenylmercuric acetate and furin-type convertases. Biochem J (1996) 0.95

gamma-Interferon decreases the level of 26 S proteasomes and changes the pattern of phosphorylation. Biochem J (2001) 0.95

Proteasome activities decrease during dexamethasone-induced apoptosis of thymocytes. Biochem J (1998) 0.95

The properties of peptidyl diazoethanes and chloroethanes as protease inactivators. Arch Biochem Biophys (1989) 0.95

The Gloucestershire Aneurysm Screening Programme: the first 2 years' experience. Eur J Vasc Surg (1993) 0.95

Active site mapping of human and rat urinary kallikreins by peptidyl chloromethyl ketones. Arch Biochem Biophys (1980) 0.94

Specific labeling of cysteine proteinases in pathogenic and nonpathogenic Entamoeba histolytica. Infect Immun (1990) 0.94

Recommendations for screening intervals for small aortic aneurysms. Br J Surg (2003) 0.93

Adenovirus early region 1A protein binds to mammalian SUG1-a regulatory component of the proteasome. Oncogene (1999) 0.93