Intracerebral cytokine mRNA expression during fatal and nonfatal alphavirus encephalitis suggests a predominant type 2 T cell response.

PubWeight™: 1.32‹?› | Rank: Top 10%

🔗 View Article (PMID 8301132)

Published in J Immunol on February 01, 1994

Authors

S L Wesselingh1, B Levine, R J Fox, S Choi, D E Griffin

Author Affiliations

1: Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205.

Articles citing this

Spontaneous autoimmune diabetes in monoclonal T cell nonobese diabetic mice. J Exp Med (1997) 2.94

Sindbis virus induces apoptosis through a caspase-dependent, CrmA-sensitive pathway. J Virol (1998) 1.71

Age-dependent resistance to lethal alphavirus encephalitis in mice: analysis of gene expression in the central nervous system and identification of a novel interferon-inducible protective gene, mouse ISG12. J Virol (2002) 1.57

Identification of genes involved in the host response to neurovirulent alphavirus infection. J Virol (2001) 1.39

Roles of gamma interferon and interleukin-4 in genetically determined resistance to Coccidioides immitis. Infect Immun (1995) 1.39

The role of CD8(+) T cells and major histocompatibility complex class I expression in the central nervous system of mice infected with neurovirulent Sindbis virus. J Virol (2000) 1.34

Chemokine and chemokine-receptor expression in human glial elements: induction by the HIV protein, Tat, and chemokine autoregulation. Am J Pathol (2000) 1.33

Inhibition of nitric oxide synthesis increases mortality in Sindbis virus encephalitis. J Virol (1996) 1.25

Gamma interferon-dependent, noncytolytic clearance of sindbis virus infection from neurons in vitro. J Virol (2005) 1.25

Yellow fever virus encephalitis: properties of the brain-associated T-cell response during virus clearance in normal and gamma interferon-deficient mice and requirement for CD4+ lymphocytes. J Virol (2001) 1.20

Cytokines in the brain during viral infection: clues to HIV-associated dementia. J Clin Invest (1997) 1.12

Expression pattern and cellular origin of cytokines in the normal and Toxoplasma gondii-infected murine brain. Am J Pathol (1997) 1.11

Roles of immunoglobulin valency and the heavy-chain constant domain in antibody-mediated downregulation of Sindbis virus replication in persistently infected neurons. J Virol (1995) 1.10

Noncytolytic clearance of sindbis virus infection from neurons by gamma interferon is dependent on Jak/STAT signaling. J Virol (2009) 1.09

CXCL10 production from cytomegalovirus-stimulated microglia is regulated by both human and viral interleukin-10. J Virol (2003) 1.08

Recovery from viral encephalomyelitis: immune-mediated noncytolytic virus clearance from neurons. Immunol Res (2010) 1.06

C3H/HeN mouse model for the evaluation of antiviral agents for the treatment of Venezuelan equine encephalitis virus infection. Antiviral Res (2008) 1.04

Sex differences in Seoul virus infection are not related to adult sex steroid concentrations in Norway rats. J Virol (2000) 1.02

Resistance of interleukin-1beta-deficient mice to fatal Sindbis virus encephalitis. J Virol (1999) 1.00

Effects of anti-E2 monoclonal antibody on sindbis virus replication in AT3 cells expressing bcl-2. J Virol (1995) 0.98

Breakdown of the blood-retinal barrier induced by activated T cells of nonneural specificity. Am J Pathol (2000) 0.94

Tumor necrosis factor-alpha modulates glutamate transport in the CNS and is a critical determinant of outcome from viral encephalomyelitis. Brain Res (2009) 0.93

The opioid receptor antagonist, naloxone, protects spinal motor neurons in a murine model of alphavirus encephalomyelitis. Exp Neurol (2007) 0.90

Acid sphingomyelinase deficiency increases susceptibility to fatal alphavirus encephalomyelitis. J Virol (2006) 0.86

Complexity of the microglial activation pathways that drive innate host responses during lethal alphavirus encephalitis in mice. ASN Neuro (2012) 0.84

The genomic signature of human rhinoviruses A, B and C. PLoS One (2012) 0.77

The Gordon Wilson lecture: unique interactions between viruses, neurons and the immune system. Trans Am Clin Climatol Assoc (1996) 0.75

Articles by these authors

(truncated to the top 100)

Initial sequencing and analysis of the human genome. Nature (2001) 212.86

Induction of autophagy and inhibition of tumorigenesis by beclin 1. Nature (1999) 23.62

Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin. Science (1995) 8.58

Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein. J Virol (1998) 7.41

Quantitative fluorescence resonance energy transfer measurements using fluorescence microscopy. Biophys J (1998) 6.27

Cloning and genomic organization of beclin 1, a candidate tumor suppressor gene on chromosome 17q21. Genomics (1999) 6.23

Conversion of lytic to persistent alphavirus infection by the bcl-2 cellular oncogene. Nature (1993) 4.81

Nutritional Regulation of Lignin Degradation by Phanerochaete chrysosporium. Appl Environ Microbiol (1981) 4.03

Molecular basis of Sindbis virus neurovirulence in mice. J Virol (1988) 3.90

Bax-independent inhibition of apoptosis by Bcl-XL. Nature (1996) 3.82

Bronchoscopic lung-volume reduction with Exhale airway stents for emphysema (EASE trial): randomised, sham-controlled, multicentre trial. Lancet (2011) 3.70

Antibody-mediated clearance of alphavirus infection from neurons. Science (1991) 3.70

Mechanism of suppression of cell-mediated immunity by measles virus. Science (1996) 3.55

Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes. Cell Death Differ (2009) 3.44

Variability of neurotransmitter concentration and nonsaturation of postsynaptic AMPA receptors at synapses in hippocampal cultures and slices. Neuron (1999) 3.29

Antigenic shift of visna virus in persistently infected sheep. Science (1977) 3.17

The autophagy effector Beclin 1: a novel BH3-only protein. Oncogene (2008) 2.94

Slow virus replication: the role of macrophages in the persistence and expression of visna viruses of sheep and goats. J Gen Virol (1982) 2.87

Search for a resonance decaying into WZ boson pairs in pp collisions. Phys Rev Lett (2010) 2.83

Characterization of Shigella dysenteriae 1 (Shiga) toxin purified by anti-Shiga toxin affinity chromatography. Infect Immun (1980) 2.82

Binding of Sindbis virus to cell surface heparan sulfate. J Virol (1998) 2.82

Selection of a fixative for identifying T cell subsets, B cells, and macrophages in paraffin-embedded mouse spleen. J Immunol Methods (1983) 2.82

Alphavirus-induced apoptosis in mouse brains correlates with neurovirulence. J Virol (1996) 2.65

Biologic consequences of Stat1-independent IFN signaling. Proc Natl Acad Sci U S A (2001) 2.56

Cytokine expression in the brain during the acquired immunodeficiency syndrome. Ann Neurol (1992) 2.52

Activation of caprine arthritis-encephalitis virus expression during maturation of monocytes to macrophages. Infect Immun (1983) 2.52

Beclin 1 contains a leucine-rich nuclear export signal that is required for its autophagy and tumor suppressor function. Cancer Res (2001) 2.51

Neuro-QOL: brief measures of health-related quality of life for clinical research in neurology. Neurology (2012) 2.50

Modulation of cell death by Bcl-XL through caspase interaction. Proc Natl Acad Sci U S A (1998) 2.42

Brain stem blood flow, pupillary response, and outcome in patients with severe head injuries. Neurosurgery (1999) 2.35

Role of the immune response in recovery from Sindbis virus encephalitis in mice. J Immunol (1977) 2.32

Bc1-2 protects mice against fatal alphavirus encephalitis. Proc Natl Acad Sci U S A (1996) 2.31

Myasthenia gravis. Study of humoral immune mechanisms by passive transfer to mice. N Engl J Med (1977) 2.23

Localization of HIV-1 in human brain using polymerase chain reaction/in situ hybridization and immunocytochemistry. Ann Neurol (1996) 2.22

Demented and nondemented patients with AIDS differ in brain-derived human immunodeficiency virus type 1 envelope sequences. J Virol (1994) 2.21

Purification and biological characterization of shiga toxin from Shigella dysenteriae 1. Infect Immun (1982) 2.21

MRI findings in Susac's syndrome. Neurology (2003) 2.17

Eating the enemy within: autophagy in infectious diseases. Cell Death Differ (2008) 2.17

Infection of monocytes during measles. J Infect Dis (1993) 2.14

Effect of plasma exchange in accelerating natalizumab clearance and restoring leukocyte function. Neurology (2009) 2.10

Intracerebral cytokine messenger RNA expression in acquired immunodeficiency syndrome dementia. Ann Neurol (1993) 2.09

Ventriculostomy infections: the effect of monitoring duration and catheter exchange in 584 patients. J Neurosurg (1996) 2.07

Beta-chemokines MCP-1 and RANTES are selectively increased in cerebrospinal fluid of patients with human immunodeficiency virus-associated dementia. Ann Neurol (1998) 2.05

Basis of neurovirulence in Sindbis virus encephalomyelitis of mice. Lab Invest (1988) 2.05

Does anaesthetic technique really matter for total knee arthroplasty? Br J Anaesth (2013) 2.04

Wisconsin Card Sorting Test performance in patients with focal frontal and posterior brain damage: effects of lesion location and test structure on separable cognitive processes. Neuropsychologia (2000) 2.03

Apoptosis as a cause of death in measles virus-infected cells. J Virol (1995) 1.97

Interferon-gamma-mediated site-specific clearance of alphavirus from CNS neurons. Science (2001) 1.95

Induction of nitric oxide synthase in demyelinating regions of multiple sclerosis brains. Ann Neurol (1994) 1.95

Viral determinants of age-dependent virulence of Sindbis virus for mice. J Virol (1993) 1.95

Clinical pathology testing recommendations for nonclinical toxicity and safety studies. AACC-DACC/ASVCP Joint Task Force. Toxicol Pathol (1992) 1.94

A precision measurement of the mass of the top quark. Nature (2004) 1.87

Role of the immune response in age-dependent resistance of mice to encephalitis due to Sindbis virus. J Infect Dis (1976) 1.86

Successful DNA immunization against measles: neutralizing antibody against either the hemagglutinin or fusion glycoprotein protects rhesus macaques without evidence of atypical measles. Nat Med (2000) 1.85

Use of a new CD4-positive HeLa cell clone for direct quantitation of infectious human immunodeficiency virus from blood cells of AIDS patients. J Infect Dis (1991) 1.85

Neurovirulent strains of Alphavirus induce apoptosis in bcl-2-expressing cells: role of a single amino acid change in the E2 glycoprotein. Proc Natl Acad Sci U S A (1994) 1.84

Purification of insulin receptor with full binding activity. J Biol Chem (1983) 1.82

Virus mutation during 'slow infection': temporal development and characterization of mutants of visna virus recovered from sheep. J Gen Virol (1978) 1.80

Mechanism of altered Sindbis virus neurovirulence associated with a single-amino-acid change in the E2 Glycoprotein. J Virol (1991) 1.80

Slow virus infection: replication and mechanisms of persistence of visna virus in sheep. J Infect Dis (1977) 1.78

Identification of a putative alphavirus receptor on mouse neural cells. J Virol (1991) 1.78

Abnormal T-cell subset proportions in vitamin-A-deficient children. Lancet (1993) 1.75

Sindbis virus induces apoptosis through a caspase-dependent, CrmA-sensitive pathway. J Virol (1998) 1.71

Cytokine mRNA expression in postischemic/reperfused myocardium. Am J Pathol (1995) 1.71

In vitro evidence for a dual role of tumor necrosis factor-alpha in human immunodeficiency virus type 1 encephalopathy. Ann Neurol (1995) 1.70

Large-plaque mutants of Sindbis virus show reduced binding to heparan sulfate, heightened viremia, and slower clearance from the circulation. J Virol (2000) 1.69

Transverse-momentum and pseudorapidity distributions of charged hadrons in pp collisions at square root of s = 7 TeV. Phys Rev Lett (2010) 1.67

Alphavirus neurovirulence: monoclonal antibodies discriminating wild-type from neuroadapted Sindbis virus. J Virol (1985) 1.64

The pathogenesis of spinal cord involvement in the encephalomyelitis of mice caused by neuroadapted Sindbis virus infection. Lab Invest (1987) 1.63

Obesity is associated with reduced self-rated general health status: evidence from a representative sample of white, black, and Hispanic Americans. Prev Med (2001) 1.63

Recombinant measles viruses with mutations in the C, V, or F gene have altered growth phenotypes in vivo. J Virol (1998) 1.62

Preoperative NT-proBNP and CRP predict perioperative major cardiovascular events in non-cardiac surgery. Heart (2009) 1.62

Measles virus infection in rhesus macaques: altered immune responses and comparison of the virulence of six different virus strains. J Infect Dis (1999) 1.62

Measles virus infection of thymic epithelium in the SCID-hu mouse leads to thymocyte apoptosis. J Virol (1996) 1.61

Gas chromatographic procedures for determination of ethanol in postmortem blood using t-butanol and methyl ethyl ketone as internal standards. Forensic Sci Int (1996) 1.61

New low-contrast vision charts: reliability and test characteristics in patients with multiple sclerosis. Mult Scler (2000) 1.60

Translocation of autophosphorylated calcium/calmodulin-dependent protein kinase II to the postsynaptic density. J Biol Chem (1997) 1.60

The role of antibody in recovery from alphavirus encephalitis. Immunol Rev (1997) 1.60

A double labeling technique for performing immunocytochemistry and in situ hybridization in virus infected cell cultures and tissues. J Virol Methods (1985) 1.60

Acute measles in patients with and without neurological involvement: distribution of measles virus antigen and RNA. J Infect Dis (1988) 1.59

The effects of focal anterior and posterior brain lesions on verbal fluency. J Int Neuropsychol Soc (1998) 1.59

Cytokine expression of macrophages in HIV-1-associated vacuolar myelopathy. Neurology (1993) 1.59

Autophagy in aging, disease and death: the true identity of a cell death impostor. Cell Death Differ (2009) 1.58

Profile of Escherichia coli O157:H7 pathogen responsible for hamburger-borne outbreak of hemorrhagic colitis and hemolytic uremic syndrome in Washington. J Clin Microbiol (1993) 1.58

Study of the mass and spin-parity of the Higgs boson candidate via its decays to Z boson pairs. Phys Rev Lett (2013) 1.56

In situ forces in the anterior cruciate ligament and its bundles in response to anterior tibial loads. J Orthop Res (1997) 1.55

Cyclin dependent kinase inhibitors and dominant negative cyclin dependent kinase 4 and 6 promote survival of NGF-deprived sympathetic neurons. J Neurosci (1997) 1.54

High level of extracellular potassium and its correlates after severe head injury: relationship to high intracranial pressure. J Neurosurg (2000) 1.54

Biological characterization of the virus causing leukoencephalitis and arthritis in goats. J Gen Virol (1980) 1.53

Measurement of the forward-backward charge asymmetry in top-quark pair production. Phys Rev Lett (2008) 1.53

Stroop performance in focal lesion patients: dissociation of processes and frontal lobe lesion location. Neuropsychologia (2001) 1.52

Age dependence of viral expression: comparative pathogenesis of two rodent-adapted strains of measles virus in mice. Infect Immun (1974) 1.51

Persistence of viral RNA in mouse brains after recovery from acute alphavirus encephalitis. J Virol (1992) 1.51

Measles encephalomyelitis--clinical and immunologic studies. N Engl J Med (1984) 1.50

Prmt5, which forms distinct homo-oligomers, is a member of the protein-arginine methyltransferase family. J Biol Chem (2001) 1.48

Efficiency of in situ hybridization as a function of probe size and fixation technique. J Virol Methods (1985) 1.47

Low pH-dependent Sindbis virus-induced fusion of BHK cells: differences between strains correlate with amino acid changes in the E1 glycoprotein. Virology (1989) 1.46

Measurement of the W boson mass with the D0 detector. Phys Rev Lett (2012) 1.46

A functional comparison of animal anterior cruciate ligament models to the human anterior cruciate ligament. Ann Biomed Eng (1998) 1.45

Long term intraparenchymal Ig secretion after acute viral encephalitis in mice. J Immunol (1992) 1.45