Published in Bull World Health Organ on January 01, 1993
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Facile and rapid analysis of three DNA polymorphisms within the human factor IX gene using the polymerase chain reaction. Br J Haematol (1991) 1.13
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A new HindIII restriction fragment length polymorphism in the hemophilia A locus. Hum Genet (1987) 1.04
Use of a BamHI polymorphism in the factor IX gene for the determination of hemophilia B carrier status. Blood (1986) 1.04
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Detection of three novel mutations in two haemophilia A patients by rapid screening of whole essential region of factor VIII gene. Lancet (1991) 1.04
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Immunoradiometric assay of procoagulant factor-VIII antigen in plasma and serum and its reduction in haemophilia. Preliminary studies on adult and fetal blood. Lancet (1978) 0.96
A DNA marker closely linked to the factor IX (haemophilia B) gene. Hum Genet (1987) 0.96
Carrier testing strategy in haemophilia A. Lancet (1986) 0.94
Restriction fragment length polymorphisms associated with factor VIII:C gene in Chinese. Hum Genet (1988) 0.92
Factor VIII levels and blood group antigens. Thromb Haemost (1983) 0.90
Diagnosis of haemophilia B carriers using intragenic oligonucleotide probes. Lancet (1986) 0.89
Trophectoderm biopsy in human blastocysts. Hum Reprod (1990) 0.88
Detection of carriers of haemophilia B. Br J Haematol (1979) 0.86
Direct estimate of the haemophilia B (factor IX deficiency) mutation rate and of the ratio of the sex-specific mutation rates in Sweden. Hum Genet (1992) 0.86
Possible absence of common polymorphisms in coagulation factor IX gene in Japanese subjects. Blood (1987) 0.83
Recombination between factor VIII:C gene and St14 locus. Lancet (1986) 0.82
Registry of DNA polymorphisms within or close to the human factor VIII and factor IX genes. For the Factor VIII/IX Subcommittee of the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis. Thromb Haemost (1992) 0.81
Restriction fragment length polymorphisms associated with the factor VIII and factor IX genes in Polynesians. J Med Genet (1991) 0.81
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MspI polymorphism in the 3' flanking region of the human factor VIII gene. Nucleic Acids Res (1987) 0.79
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The varying frequencies of five DNA polymorphisms of X-linked coagulant factor IX in eight ethnic groups. Am J Hum Genet (1991) 0.78
Carrier detection in Japanese hemophilia A by use of three intragenic and two extragenic factor VIII DNA probes: a study of 24 kindreds. J Lab Clin Med (1988) 0.77
Carrier detection in hemophilia A: a cooperative international study. II. The efficacy of a universal discriminant. Blood (1986) 0.77
Effect of oral contraceptives on factor VIII clotting activity and factor VIII related antigen in normal women. J Clin Pathol (1975) 0.76
A TaqI polymorphism adjacent to the factor VIII gene (F8C). Nucleic Acids Res (1991) 0.76
Detection of hemophilia carriers during pregnancy. Blood (1982) 0.76
Oral contraception and the detection of carriers in haemophilia B. Thromb Res (1978) 0.76
Genetic diagnosis before the eighth gestational week. Obstet Gynecol (1991) 0.76
Absence of nasal bone in fetuses with trisomy 21 at 11-14 weeks of gestation: an observational study. Lancet (2001) 5.64
Outbreak of hepatitis A among Italian patients with haemophilia. Lancet (1992) 5.64
Update on the pathophysiology and classification of von Willebrand disease: a report of the Subcommittee on von Willebrand Factor. J Thromb Haemost (2006) 4.58
Hyperhomocysteinemia as a risk factor for deep-vein thrombosis. N Engl J Med (1996) 4.11
Insulin glargine use and short-term incidence of malignancies-a population-based follow-up study in Sweden. Diabetologia (2009) 3.82
Gene deletions correlate with the development of alloantibodies in von Willebrand disease. J Clin Invest (1987) 3.73
Genetic relationships of Asians and Northern Europeans, revealed by Y-chromosomal DNA analysis. Am J Hum Genet (1997) 3.54
Transmission of non-A, non-B hepatitis by heat-treated factor VIII concentrate. Lancet (1985) 3.53
Are randomized clinical trials the only truth? Not always. J Thromb Haemost (2006) 3.34
Eliminating parvovirus B19 from blood products. Lancet (1994) 2.85
Elevated expression of axin2 and hnkd mRNA provides evidence that Wnt/beta -catenin signaling is activated in human colon tumors. Proc Natl Acad Sci U S A (2001) 2.77
Uncertain times for research on hemophilia and allied disorders. J Thromb Haemost (2005) 2.74
Effects of exposure to air pollution on blood coagulation. J Thromb Haemost (2006) 2.52
Audit of prenatal diagnosis for haemoglobin disorders in the United Kingdom: the first 20 years. BMJ (1997) 2.40
Two different molecular organizations account for the single alpha-globin gene of the alpha-thalassemia-2 genotype. J Clin Invest (1980) 2.38
High risk of cerebral-vein thrombosis in carriers of a prothrombin-gene mutation and in users of oral contraceptives. N Engl J Med (1998) 2.30
Preliminary experience with endoscopic laser surgery for severe twin-twin transfusion syndrome. N Engl J Med (1995) 2.29
Oligospecificity of the cellular adhesion receptor Mac-1 encompasses an inducible recognition specificity for fibrinogen. J Cell Biol (1988) 2.28
ICSH recommendations for the measurement of haemoglobin A2. Int J Lab Hematol (2011) 2.23
Effects on bleeding complications of pharmacogenetic testing for initial dosing of vitamin K antagonists: a systematic review and meta-analysis. J Thromb Haemost (2014) 2.15
Patients with type 3 severe von Willebrand disease are not protected against atherosclerosis: results from a multicenter study in 47 patients. Circulation (2004) 2.12
Genetic and clinical features of hemoglobin H disease in Chinese patients. N Engl J Med (2000) 2.07
Heightened interaction between platelets and factor VIII/von Willebrand factor in a new subtype of von Willebrand's disease. N Engl J Med (1980) 2.07
1-Deamino-8-d-arginine vasopressin: a new pharmacological approach to the management of haemophilia and von Willebrands' diseases. Lancet (1977) 2.06
An association between the common hereditary hemochromatosis mutation and the factor V Leiden allele in a population with thrombosis. Blood (1998) 2.03
Inherited thrombophilia: pathogenesis, clinical syndromes, and management. Blood (1996) 2.02
Expression studies on a novel type 2B variant of the von Willebrand factor gene (R1308L) characterized by defective collagen binding. J Thromb Haemost (2005) 2.02
Inherited thrombophilia: Part 1. Thromb Haemost (1996) 2.00
The risk of recurrent deep venous thrombosis among heterozygous carriers of both factor V Leiden and the G20210A prothrombin mutation. N Engl J Med (1999) 1.97
Current outcome of antenally diagnosed cystic lung disease. J Pediatr Surg (2004) 1.95
Factor VIIa and antithrombin III activity during severe sepsis and septic shock in neutropenic patients. Blood (1996) 1.88
Factor V gene mutation is a risk factor for cerebral venous thrombosis. Thromb Haemost (1996) 1.83
Prothrombotic genetic risk factors in young survivors of myocardial infarction. Blood (1999) 1.81
Mutations causing hemophilia B: direct estimate of the underlying rates of spontaneous germ-line transitions, transversions, and deletions in a human gene. Am J Hum Genet (1990) 1.78
A randomized clinical trial of prophylaxis in children with hemophilia A (the ESPRIT Study). J Thromb Haemost (2011) 1.75
Treatment of severe von Willebrand disease with a high-purity von Willebrand factor concentrate (Wilfactin): a prospective study of 50 patients. J Thromb Haemost (2007) 1.69
Genetic screening for hemophilia A (classic hemophilia) with a polymorphic DNA probe. N Engl J Med (1985) 1.67
The incidence and distribution of CpG----TpG transitions in the coagulation factor IX gene. A fresh look at CpG mutational hotspots. Nucleic Acids Res (1990) 1.64
Rate of inhibitor development in previously untreated hemophilia A patients treated with plasma-derived or recombinant factor VIII concentrates: a systematic review. J Thromb Haemost (2010) 1.62
Impact, diagnosis and treatment of von Willebrand disease. Thromb Haemost (2000) 1.62
Effect on blood coagulation of massive intravascular haemolysis. Blood (1969) 1.61
Absence of antibodies to AIDS virus in haemophiliacs treated with heat-treated Factor VIII concentrate. Lancet (1985) 1.60
Osteogenesis imperfecta and other skeletal dysplasias presenting with increased nuchal translucency in the first trimester. Am J Med Genet (2001) 1.58
Different bleeding risk in type 2A and 2M von Willebrand disease: a 2-year prospective study in 107 patients. J Thromb Haemost (2012) 1.57
A 23bp insertion in the endothelial protein C receptor (EPCR) gene impairs EPCR function. Thromb Haemost (2001) 1.57
Purinoceptors on blood platelets: further pharmacological and clinical evidence to suggest the presence of two ADP receptors. Br J Haematol (1995) 1.55
International, collaborative assessment of 146,000 prenatal karyotypes: expected limitations if only chromosome-specific probes and fluorescent in-situ hybridization are used. Hum Reprod (1999) 1.54
A multicenter pharmacokinetic study of the B-domain deleted recombinant factor VIII concentrate using different assays and standards. J Thromb Haemost (2003) 1.53
Hepatitis C virus transmission by monoclonal antibody purified factor VIII concentrate. Lancet (1990) 1.53
The addition of continuous intravenous infusion of ketorolac to a patient-controlled analgetic morphine regime reduced postoperative myocardial ischemia in patients undergoing elective total hip or knee arthroplasty. Anesth Analg (1997) 1.52
Compatible scales for progressive and additive MRI assessments of haemophilic arthropathy. Haemophilia (2005) 1.52
Reduction in transmission of hepatitis C after the introduction of a heat-treatment step in the production of C1-inhibitor concentrate. Transfusion (1995) 1.48
Type and location of venous thromboembolism in patients with factor V Leiden or prothrombin G20210A and in those with no thrombophilia. J Thromb Haemost (2006) 1.48
Different risks of thrombosis in four coagulation defects associated with inherited thrombophilia: a study of 150 families. Blood (1998) 1.47
Mechanism of plasminogen activator and factor VIII increase after vasoactive drugs. Br J Haematol (1975) 1.47
Factors affecting adherence to guidelines for antithrombotic therapy in elderly patients with atrial fibrillation admitted to internal medicine wards. Eur J Intern Med (2010) 1.47
Rare coagulation disorders. Thromb Haemost (1999) 1.46
Status of present and candidate international reference preparations (IRP) of thromboplastin for the prothrombin time. A report of the Subcommittee for Control of Anticoagulation. Thromb Haemost (1993) 1.45
Risk factors for deep venous thrombosis of the upper extremities. Ann Intern Med (1997) 1.45
Multicentric evaluation of a new PT reagent based on recombinant human tissue factor and synthetic phospholipids. Thromb Haemost (1994) 1.43
A simplified procedure for thromboplastin calibration--the usefulness of lyophilized plasmas assessed in a collaborative study. Thromb Haemost (1996) 1.43
Difficulties in the diagnosis of congenital toxoplasmosis by cordocentesis. Case report. Br J Obstet Gynaecol (1991) 1.42
Arg506Gln factor V mutation and cerebral ischemia in the young. Stroke (1996) 1.42
A three-outcome design for phase II clinical trials. Control Clin Trials (2001) 1.42
Randomized study of early amniocentesis versus chorionic villus sampling: a technical and cytogenetic comparison of 650 patients. Ultrasound Obstet Gynecol (1991) 1.41
Hemophilia and nonprogressing human immunodeficiency virus type 1 infection. Blood (1997) 1.41
Prevention and control of haemoglobinopathies. Bull World Health Organ (1995) 1.41
A new strategy for prenatal diagnosis of homozygous alpha(0)-thalassemia. Ultrasound Obstet Gynecol (2006) 1.40
Multimeric pattern of plasma and platelet von Willebrand factor is normal in uremic patients. Am J Hematol (1993) 1.40
Factor VII clotting assay: influence of different thromboplastins and factor VII-deficient plasmas. CISMEL Study Group. Thromb Haemost (1991) 1.40
Linkage of polymorphic congenital cataract to the gamma-crystallin gene locus on human chromosome 2q33-35. Hum Mol Genet (1996) 1.40
Frequency of factor V Arg506 Gln in Italians. Thromb Haemost (1996) 1.39
[Thalassemia, heading for Sweden. A new patient group at Swedish pediatric clinics]. Lakartidningen (1996) 1.39
Resistance to activated protein C mimicking dysfunctional protein C: diagnostic approach. Blood Coagul Fibrinolysis (1996) 1.39
Poor comparability of prothrombin fragment 1 + 2 values measured by two commercial ELISA methods: influence of different anticoagulants and standards. Thromb Haemost (1994) 1.38
Calibration of local systems with lyophilized calibrant plasmas improves the interlaboratory variability of the INR in the Italian external quality assessment scheme. Thromb Haemost (1999) 1.38
Safety and immunogenicity of HIV-1 Tat toxoid in immunocompromised HIV-1-infected patients. J Hum Virol (1999) 1.38
Deamino-8-D-arginine vasopressin shortens the bleeding time in uremia. N Engl J Med (1983) 1.38
Factor VIII:C increases after desmopressin in a subgroup of patients with autosomal recessive severe von Willebrand disease. Br J Haematol (1995) 1.37
Genetic diagnosis of haemophilia and other inherited bleeding disorders. Haemophilia (2006) 1.36
Haemophilia B: database of point mutations and short additions and deletions--third edition, 1992. Nucleic Acids Res (1992) 1.36
RFLP for a human von Willebrand factor (vWF) cDNA clone, pvWF1100. Nucleic Acids Res (1985) 1.36
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Report of the Working Party on Acquired Inhibitors of Coagulation: studies of the "lupus" anticoagulant. Thromb Haemost (1983) 1.34
Assessment of fetal compromise by Doppler ultrasound investigation of the fetal circulation. Arterial, intracardiac, and venous blood flow velocity studies. Circulation (1995) 1.34
Inherited thrombophilia: Part 2. Thromb Haemost (1996) 1.34
Factor IX inhibitors and anaphylaxis in hemophilia B. J Pediatr Hematol Oncol (1997) 1.34
Primary prophylaxis in severe haemophilia should be started at an early age but can be individualized. Br J Haematol (1999) 1.32
Identification of a new congenital defect of platelet function characterized by severe impairment of platelet responses to adenosine diphosphate. Blood (1992) 1.31
Haemophilia B: database of point mutations and short additions and deletions--second edition. Nucleic Acids Res (1991) 1.29
Deficiencies of protein C, an inhibitor of blood coagulation. Lancet (1982) 1.28
Persistent activation of coagulation mechanism in unstable angina and myocardial infarction. Circulation (1994) 1.28