Published in Proc Natl Acad Sci U S A on October 15, 1993
Clinical, cellular, and molecular factors that contribute to antifungal drug resistance. Clin Microbiol Rev (1998) 9.76
Cryptococcosis in the era of AIDS--100 years after the discovery of Cryptococcus neoformans. Clin Microbiol Rev (1995) 8.81
Molecular markers reveal that population structure of the human pathogen Candida albicans exhibits both clonality and recombination. Proc Natl Acad Sci U S A (1996) 3.53
Resistance mechanisms in clinical isolates of Candida albicans. Antimicrob Agents Chemother (2002) 3.38
Cryptic speciation and recombination in the aflatoxin-producing fungus Aspergillus flavus. Proc Natl Acad Sci U S A (1998) 2.96
In Candida albicans, white-opaque switchers are homozygous for mating type. Genetics (2002) 2.96
The ins and outs of DNA fingerprinting the infectious fungi. Clin Microbiol Rev (2000) 2.95
Evolution of drug resistance in experimental populations of Candida albicans. J Bacteriol (2000) 2.58
The evolutionary biology and population genetics underlying fungal strain typing. Clin Microbiol Rev (1999) 2.46
Molecular phylogenetics of Candida albicans. Eukaryot Cell (2007) 2.41
Parity among the randomly amplified polymorphic DNA method, multilocus enzyme electrophoresis, and Southern blot hybridization with the moderately repetitive DNA probe Ca3 for fingerprinting Candida albicans. J Clin Microbiol (1997) 2.35
The evolution of sex: a perspective from the fungal kingdom. Microbiol Mol Biol Rev (2010) 2.24
Multilocus sequence typing of Candida glabrata reveals geographically enriched clades. J Clin Microbiol (2003) 2.18
Optimization and validation of multilocus sequence typing for Candida albicans. J Clin Microbiol (2003) 2.18
Skin facilitates Candida albicans mating. Infect Immun (2003) 1.99
Heterozygosity, heteromorphy, and phylogenetic trees in asexual eukaryotes. Genetics (1996) 1.97
Ca3 fingerprinting of Candida albicans bloodstream isolates from the United States, Canada, South America, and Europe reveals a European clade. J Clin Microbiol (2002) 1.80
Microsatellite polymorphism in the promoter sequence of the elongation factor 3 gene of Candida albicans as the basis for a typing system. J Clin Microbiol (1997) 1.65
Clade-specific flucytosine resistance is due to a single nucleotide change in the FUR1 gene of Candida albicans. Antimicrob Agents Chemother (2004) 1.49
Flucytosine resistance is restricted to a single genetic clade of Candida albicans. Antimicrob Agents Chemother (2004) 1.49
Fluconazole- and itraconazole-resistant Candida albicans strains from AIDS patients: multilocus enzyme electrophoresis analysis and antifungal susceptibilities. J Clin Microbiol (1995) 1.44
Candida albicans strain maintenance, replacement, and microvariation demonstrated by multilocus sequence typing. J Clin Microbiol (2006) 1.43
Multilocus genotypes and DNA fingerprints Do not predict variation in azole resistance among clinical isolates of Candida albicans. Antimicrob Agents Chemother (1999) 1.40
Infrequent genetic exchange and recombination in the mitochondrial genome of Candida albicans. J Bacteriol (2001) 1.32
Typing Candida albicans oral isolates from human immunodeficiency virus-infected patients by multilocus enzyme electrophoresis and DNA fingerprinting. J Clin Microbiol (1996) 1.32
Genome-wide single-nucleotide polymorphism map for Candida albicans. Eukaryot Cell (2004) 1.31
Comparative genotyping of Candida albicans bloodstream and nonbloodstream isolates at a polymorphic microsatellite locus. J Clin Microbiol (2000) 1.27
Clinical isolates of Histoplasma capsulatum from Indianapolis, Indiana, have a recombining population structure. J Clin Microbiol (1996) 1.25
Formation of azole-resistant Candida albicans by mutation of sterol 14-demethylase P450. Antimicrob Agents Chemother (1999) 1.21
Genetic polymorphism of Aspergillus fumigatus in clinical samples from patients with invasive aspergillosis: investigation using multiple typing methods. J Clin Microbiol (2001) 1.15
Lack of genetic differentiation between two geographically diverse samples of Candida albicans isolated from patients infected with human immunodeficiency virus. J Bacteriol (1999) 1.14
MP1 homologue-based multilocus sequence system for typing the pathogenic fungus Penicillium marneffei: a novel approach using lineage-specific genes. J Clin Microbiol (2007) 1.12
Increased virulence and competitive advantage of a/alpha over a/a or alpha/alpha offspring conserves the mating system of Candida albicans. Genetics (2005) 1.11
Interaction between genetic background and the mating-type locus in Cryptococcus neoformans virulence potential. Genetics (2005) 1.10
Stability of allelic frequencies and distributions of Candida albicans microsatellite loci from U.S. population-based surveillance isolates. J Clin Microbiol (2003) 1.09
Development of two species-specific fingerprinting probes for broad computer-assisted epidemiological studies of Candida tropicalis. J Clin Microbiol (1996) 1.08
Is sex better? Parasites say "no". Proc Natl Acad Sci U S A (1998) 1.08
Increased expression of Candida albicans secretory proteinase, a putative virulence factor, in isolates from human immunodeficiency virus-positive patients. J Clin Microbiol (1995) 1.07
Phenotypic and genotypic characterization of unusual vaginal isolates of Candida albicans from Africa. J Clin Microbiol (1995) 1.05
Mating is rare within as well as between clades of the human pathogen Candida albicans. Fungal Genet Biol (2007) 1.02
High-frequency, in vitro reversible switching of Candida lusitaniae clinical isolates from amphotericin B susceptibility to resistance. Antimicrob Agents Chemother (1999) 1.01
Genetic structure of Candida glabrata populations in AIDS and non-AIDS patients. J Clin Microbiol (2002) 0.97
Genotyping of Candida albicans oral strains from healthy individuals by polymorphic microsatellite locus analysis. J Clin Microbiol (2003) 0.96
Sex proportions of Haemoproteus blood parasites and local mate competition. Proc Natl Acad Sci U S A (1995) 0.95
Effects of ploidy and mating type on virulence of Candida albicans. Infect Immun (2005) 0.93
Efficient and rapid identification of Candida albicans allelic status using SNP-RFLP. FEMS Yeast Res (2009) 0.93
Phenotypic analysis and virulence of Candida albicans LIG4 mutants. Infect Immun (2001) 0.92
Sequence finishing and gene mapping for Candida albicans chromosome 7 and syntenic analysis against the Saccharomyces cerevisiae genome. Genetics (2005) 0.92
Clonal population structure and genetic diversity of Candida albicans in AIDS patients from Abidjan (Côte d'Ivoire). Proc Natl Acad Sci U S A (2006) 0.91
Rad52 function prevents chromosome loss and truncation in Candida albicans. Mol Microbiol (2011) 0.89
A single SNP, G929T (Gly310Val), determines the presence of a functional and a non-functional allele of HIS4 in Candida albicans SC5314: detection of the non-functional allele in laboratory strains. Fungal Genet Biol (2007) 0.87
Genetic multilocus studies of different strains of Cryptococcus neoformans: taxonomy and genetic structure. J Clin Microbiol (1999) 0.85
Parasexual Ploidy Reduction Drives Population Heterogeneity Through Random and Transient Aneuploidy in Candida albicans. Genetics (2015) 0.82
Role of the homologous recombination genes RAD51 and RAD59 in the resistance of Candida albicans to UV light, radiomimetic and anti-tumor compounds and oxidizing agents. Fungal Genet Biol (2010) 0.82
Endemic genotypes of Candida albicans causing fungemia are frequent in the hospital. J Clin Microbiol (2013) 0.80
The frequency of sex in fungi. Philos Trans R Soc Lond B Biol Sci (2016) 0.80
Candida albicans: genotyping methods and clade related phenotypic characteristics. Braz J Microbiol (2010) 0.79
The structure and retrotransposition mechanism of LTR-retrotransposons in the asexual yeast Candida albicans. Virulence (2014) 0.76
Genetic diversity among clinical isolates of Candida glabrata analyzed by randomly amplified polymorphic DNA and multilocus enzyme electrophoresis analyses. J Clin Microbiol (2003) 0.76
Analysis of Repair Mechanisms following an Induced Double-Strand Break Uncovers Recessive Deleterious Alleles in the Candida albicans Diploid Genome. MBio (2016) 0.75
The intraspecies diversity of C. albicans triggers qualitatively and temporally distinct host responses that determine the balance between commensalism and pathogenicity. Mucosal Immunol (2017) 0.75
Genetic diversity and structure in Escherichia coli populations. Science (1980) 11.19
Oral candidiasis in high-risk patients as the initial manifestation of the acquired immunodeficiency syndrome. N Engl J Med (1984) 6.11
Population genetics of pathogenic bacteria. Microb Pathog (1987) 5.59
Virulent strains of Toxoplasma gondii comprise a single clonal lineage. Nature (1992) 4.92
DNA content, kinetic complexity, and the ploidy question in Candida albicans. Mol Cell Biol (1982) 4.64
Heterozygosity and segregation in Candida albicans. Mol Gen Genet (1980) 4.56
Are eukaryotic microorganisms clonal or sexual? A population genetics vantage. Proc Natl Acad Sci U S A (1991) 4.30
A clonal theory of parasitic protozoa: the population structures of Entamoeba, Giardia, Leishmania, Naegleria, Plasmodium, Trichomonas, and Trypanosoma and their medical and taxonomical consequences. Proc Natl Acad Sci U S A (1990) 4.07
Natural heterozygosity in Candida albicans. J Bacteriol (1981) 3.53
Genetics of Candida albicans. Microbiol Rev (1990) 3.51
Hybrid formation between African trypanosomes during cyclical transmission. Nature (1986) 2.61
Natural populations of Trypanosoma cruzi, the agent of Chagas disease, have a complex multiclonal structure. Proc Natl Acad Sci U S A (1986) 2.48
Isoenzyme biotypes of Candida species. J Clin Microbiol (1989) 2.36
Recombination analysis of naturally diploid Candida albicans. J Bacteriol (1982) 2.20
Physical and genetic mapping of Candida albicans: several genes previously assigned to chromosome 1 map to chromosome R, the rDNA-containing linkage group. Infect Immun (1991) 1.79
Population structure of multilocus associations. Proc Natl Acad Sci U S A (1981) 1.55
Epidemiological analysis of Candida albicans strains by multilocus enzyme electrophoresis. J Clin Microbiol (1993) 1.49
Oral candidiasis in HIV infection: pseudomembranous and erythematous candidiasis show similar rates of progression to AIDS. AIDS (1991) 1.20
[Treatment and secondary prophylaxis with fluconazole for oropharyngeal candidiasis in HIV-positive patients. A mycological analysis of failures]. Pathol Biol (Paris) (1992) 1.01
Enzyme variability in the Drosophila willistoni group. IV. Genic variation in natural populations of Drosophila willistoni. Genetics (1972) 9.38
High-resolution minisatellite-based typing as a portable approach to global analysis of Mycobacterium tuberculosis molecular epidemiology. Proc Natl Acad Sci U S A (2001) 6.97
Polymorphisms in continental and island populations of Drosophila willistoni. Proc Natl Acad Sci U S A (1971) 6.28
Testing differentiation in diploid populations. Genetics (1996) 6.23
Evidence for positive selection in the superoxide dismutase (Sod) region of Drosophila melanogaster. Genetics (1994) 5.05
Phylogeny of the malarial genus Plasmodium, derived from rRNA gene sequences. Proc Natl Acad Sci U S A (1994) 4.50
Are eukaryotic microorganisms clonal or sexual? A population genetics vantage. Proc Natl Acad Sci U S A (1991) 4.30
A new consensus for Trypanosoma cruzi intraspecific nomenclature: second revision meeting recommends TcI to TcVI. Mem Inst Oswaldo Cruz (2009) 4.27
M13-tailed primers improve the readability and usability of microsatellite analyses performed with two different allele-sizing methods. Biotechniques (2001) 4.14
A clonal theory of parasitic protozoa: the population structures of Entamoeba, Giardia, Leishmania, Naegleria, Plasmodium, Trichomonas, and Trypanosoma and their medical and taxonomical consequences. Proc Natl Acad Sci U S A (1990) 4.07
Genetic variation in natural populations of five Drosophila species and the hypothesis of the selective neutrality of protein polymorphisms. Genetics (1974) 3.97
Testing heterozygote excess and deficiency. Genetics (1995) 3.80
The unique mutation in ace-1 giving high insecticide resistance is easily detectable in mosquito vectors. Insect Mol Biol (2004) 3.74
Evolutionary origin of Plasmodium and other Apicomplexa based on rRNA genes. Proc Natl Acad Sci U S A (1995) 3.73
Enzyme variability in the Drosophila willistoni group. I. Genetic differentiation among sibling species. Proc Natl Acad Sci U S A (1970) 3.59
Genetic load in natural populations: is it compatible with the hypothesis that many polymorphisms are maintained by natural selection? Genetics (1974) 3.45
Epidemiologic features and clinical presentation of acute Q fever in hospitalized patients: 323 French cases. Am J Med (1992) 3.13
Genetic and biochemical basis of enzyme activity variation in natural populations. I. Alcohol dehydrogenase in Drosophila melanogaster. Genetics (1978) 3.05
Mutation and selection in bacterial populations: alternatives to the hypothesis of directed mutation. Proc Natl Acad Sci U S A (1989) 2.95
Evolutionary origin of human and primate malarias: evidence from the circumsporozoite protein gene. Mol Biol Evol (1995) 2.93
Malaria's Eve: evidence of a recent population bottleneck throughout the world populations of Plasmodium falciparum. Proc Natl Acad Sci U S A (1998) 2.76
Origin of the metazoan phyla: molecular clocks confirm paleontological estimates. Proc Natl Acad Sci U S A (1998) 2.72
Natural populations of Trypanosoma cruzi, the agent of Chagas disease, have a complex multiclonal structure. Proc Natl Acad Sci U S A (1986) 2.48
Role of genomic typing in taxonomy, evolutionary genetics, and microbial epidemiology. Clin Microbiol Rev (2001) 2.37
Genetic characterization of six parasitic protozoa: parity between random-primer DNA typing and multilocus enzyme electrophoresis. Proc Natl Acad Sci U S A (1993) 2.36
Genetic polymorphism and natural selection in the malaria parasite Plasmodium falciparum. Genetics (1998) 2.36
The three mouse multidrug resistance (mdr) genes are expressed in a tissue-specific manner in normal mouse tissues. Mol Cell Biol (1989) 2.35
Parity among the randomly amplified polymorphic DNA method, multilocus enzyme electrophoresis, and Southern blot hybridization with the moderately repetitive DNA probe Ca3 for fingerprinting Candida albicans. J Clin Microbiol (1997) 2.35
Efficiencies of four versions of the AMPLICOR HIV-1 MONITOR test for quantification of different subtypes of human immunodeficiency virus type 1. J Clin Microbiol (1999) 2.30
Nucleotide sequences provide evidence of genetic exchange among distantly related lineages of Trypanosoma cruzi. Proc Natl Acad Sci U S A (2001) 2.29
Competition between species: theoretical models and experimental tests. Theor Popul Biol (1973) 2.24
A population cage test for heterosis in Drosophila pseudoobscura. Genetics (1970) 2.23
Amplification of an esterase gene is responsible for insecticide resistance in a California Culex mosquito. Science (1986) 2.20
Optimized PCR using patient blood samples for diagnosis and follow-up of visceral Leishmaniasis, with special reference to AIDS patients. J Clin Microbiol (2000) 2.12
The bZip transcription factor Cap1p is involved in multidrug resistance and oxidative stress response in Candida albicans. J Bacteriol (1999) 2.11
Cloning and characterization of a second member of the mouse mdr gene family. Mol Cell Biol (1988) 2.06
Experimental invalidation of the principle of competitive exclusion. Nature (1969) 2.06
The kdr mutation occurs in the Mopti form of Anopheles gambiae s.s. through introgression. Insect Mol Biol (2000) 2.04
Genetic differentiation within and between species of the Drosophila willistoni group. Proc Natl Acad Sci U S A (1974) 2.04
Identification of six Trypanosoma cruzi phylogenetic lineages by random amplified polymorphic DNA and multilocus enzyme electrophoresis. Int J Parasitol (2000) 2.03
Genetic response to environmental heterogeneity. Nature (1974) 1.95
Enzyme variability in the Drosophila Willistoni group. V. Genic variation in natural populations of Drosophila equinoxialis. Genet Res (1972) 1.92
International variability of ages at menarche and menopause: patterns and main determinants. Hum Biol (2001) 1.85
Global models of growth and competition. Proc Natl Acad Sci U S A (1973) 1.85
Characterisation of large and small subunit rRNA and mini-exon genes further supports the distinction of six Trypanosoma cruzi lineages. Int J Parasitol (2001) 1.81
Tracking the evolution of insecticide resistance in the mosquito Culex pipiens. Nature (1999) 1.81
Climate change and the integrity of science. Science (2010) 1.80
Adaptive response due to changes in gene regulation: a study with Drosophila. Proc Natl Acad Sci U S A (1977) 1.78
Comparative evaluation of three assays for the quantitation of human immunodeficiency virus type 1 RNA in plasma. J Med Virol (1996) 1.77
Allozymes as diagnostic characters of sibling species of Drosophila. Proc Natl Acad Sci U S A (1972) 1.75
AP1-mediated multidrug resistance in Saccharomyces cerevisiae requires FLR1 encoding a transporter of the major facilitator superfamily. J Biol Chem (1997) 1.72
Genetic variability in a temperate intertidal phoronid, Phoronopsis viridis. Biochem Genet (1974) 1.72
Genetic diversity of protease and reverse transcriptase sequences in non-subtype-B human immunodeficiency virus type 1 strains: evidence of many minor drug resistance mutations in treatment-naive patients. J Clin Microbiol (2000) 1.70
Biological evolution: natural selection or random walk? Am Sci (1975) 1.66
Temporal frequency changes of enzyme and chromosomal polymorphisms in natural populations of Drosophila. Proc Natl Acad Sci U S A (1973) 1.64
[Acquired cytomegalovirus infections in immunocompetent adults: 116 cases]. Presse Med (1998) 1.63
The Candida albicans CDR3 gene codes for an opaque-phase ABC transporter. J Bacteriol (1997) 1.62
Gene frequency comparisons between taxa: support for the natural selection of protein polymorphisms. Proc Natl Acad Sci U S A (1974) 1.60
Search for supersymmetry using final states with one lepton, jets, and missing transverse momentum with the ATLAS detector in √s=7 TeV pp collisions. Phys Rev Lett (2011) 1.60
Evidence of natural selection in molecular evolution. Nat New Biol (1973) 1.60
Population structure and genetic typing of Trypanosoma cruzi, the agent of Chagas disease: a multilocus enzyme electrophoresis approach. Parasitology (2000) 1.59
Trade-off between r-selection and K-selection in Drosophila populations. Proc Natl Acad Sci U S A (1981) 1.58
Population structure and recent evolution of Plasmodium falciparum. Proc Natl Acad Sci U S A (2000) 1.56
DNA variation at the Sod locus of Drosophila melanogaster: an unfolding story of natural selection. Proc Natl Acad Sci U S A (1997) 1.56
Proposed changes for NIH's Center for Scientific Review. Panel on Scientific Boundaries for Review. Center for Scientific Review Advisory Committee, National Institutes of Health. Science (1999) 1.52
Rapid isolation of DNA from Actinomyces. Ann Inst Pasteur Microbiol (1988) 1.52
Evolution of fitness in experimental populations of Drosophila serrata. Science (1965) 1.52
Structural analysis of the ADHS electromorph of Drosophila melanogaster. Proc Natl Acad Sci U S A (1978) 1.52
Visceral leishmaniasis and HIV-1 co-infection in southern France. Trans R Soc Trop Med Hyg (1995) 1.51
Estimation and interpretation of genetic distance in empirical studies. Genet Res (1982) 1.51
Comparison of various sample preparation methods for PCR diagnosis of visceral leishmaniasis using peripheral blood. J Clin Microbiol (2001) 1.50
Darwinian fitness and adaptedness in experimental populations of Drosophilia willistoni. Genetica (1972) 1.49
Linkage disequilibrium in natural populations of Trypanosoma cruzi (flagellate), the agent of Chagas' disease. J Protozool (1988) 1.48
Prevalence of virulence genes and clonality in Escherichia coli strains that cause bacteremia in cancer patients. Infect Immun (2000) 1.47
Plasmodium falciparum antigenic diversity: evidence of clonal population structure. Proc Natl Acad Sci U S A (1997) 1.47
Insecticide resistance and dominance levels. J Econ Entomol (2000) 1.45
Antiretroviral treatment French guidelines 2013: economics influencing science. J Antimicrob Chemother (2014) 1.45
Fluconazole- and itraconazole-resistant Candida albicans strains from AIDS patients: multilocus enzyme electrophoresis analysis and antifungal susceptibilities. J Clin Microbiol (1995) 1.44
Exon/intron structure of aldehyde dehydrogenase genes supports the "introns-late" theory. Proc Natl Acad Sci U S A (1997) 1.42
Observation of a centrality-dependent dijet asymmetry in lead-lead collisions at sqrt[S(NN)] =2.76 TeV with the ATLAS detector at the LHC. Phys Rev Lett (2010) 1.41
Functional complementation of the yeast divalent cation transporter family SMF by NRAMP2, a member of the mammalian natural resistance-associated macrophage protein family. J Biol Chem (1997) 1.41
"Clonal" population structure of the malaria agent Plasmodium falciparum in high-infection regions. Proc Natl Acad Sci U S A (2005) 1.41
Predicted and observed alleles of Plasmodium falciparum merozoite surface protein-1 (MSP-1), a potential malaria vaccine antigen. Mol Biochem Parasitol (1998) 1.40
Measurement of dijet azimuthal decorrelations in pp collisions at sqrt(s)=7 TeV. Phys Rev Lett (2011) 1.39
The origin of antigenic diversity in Plasmodium falciparum. Parasitol Today (2000) 1.39
Characterization of insensitive acetylcholinesterase (ace-1R) in Anopheles gambiae (Diptera: Culicidae): resistance levels and dominance. J Med Entomol (2007) 1.39
Complete amino acid sequence of copper-zinc superoxide dismutase from Drosophila melanogaster. Arch Biochem Biophys (1985) 1.38
Dominance of insecticide resistance presents a plastic response. Genetics (1996) 1.38
Use of polymerase chain reaction to amplify segments outside boundaries of known sequences. Methods Enzymol (1993) 1.36
Chromosome interactions in Drosophila melanogaster. I. Viability studies. Genetics (1982) 1.36
Phylogeny of Drosophila and related genera inferred from the nucleotide sequence of the Cu,Zn Sod gene. J Mol Evol (1994) 1.35
Evolution of mitochondrial DNA in Drosophila subobscura. Proc Natl Acad Sci U S A (1986) 1.35
Determination of the strange-quark density of the proton from ATLAS measurements of the W→ℓν and Z→ℓℓ cross sections. Phys Rev Lett (2012) 1.34