P J Farnham

Author PubWeight™ 104.44‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties. Cell 1992 9.19
2 Use of chromatin immunoprecipitation to clone novel E2F target promoters. Mol Cell Biol 2001 5.61
3 c-Myc target gene specificity is determined by a post-DNAbinding mechanism. Proc Natl Acad Sci U S A 1998 3.81
4 A protein synthesis-dependent increase in E2F1 mRNA correlates with growth regulation of the dihydrofolate reductase promoter. Mol Cell Biol 1993 3.38
5 Multiple DNA elements are required for the growth regulation of the mouse E2F1 promoter. Genes Dev 1994 3.27
6 The HIP1 binding site is required for growth regulation of the dihydrofolate reductase gene promoter. Mol Cell Biol 1992 3.06
7 Transcription initiation from the dihydrofolate reductase promoter is positioned by HIP1 binding at the initiation site. Mol Cell Biol 1990 2.96
8 Target gene specificity of E2F and pocket protein family members in living cells. Mol Cell Biol 2000 2.85
9 Mre11 complex and DNA replication: linkage to E2F and sites of DNA synthesis. Mol Cell Biol 2001 2.85
10 Myc versus USF: discrimination at the cad gene is determined by core promoter elements. Mol Cell Biol 1997 2.62
11 Synthetic sites for transcription termination and a functional comparison with tryptophan operon termination sites in vitro. Proc Natl Acad Sci U S A 1981 2.62
12 Computer-assisted identification of cell cycle-related genes: new targets for E2F transcription factors. J Mol Biol 2001 2.56
13 Rho-independent termination: dyad symmetry in DNA causes RNA polymerase to pause during transcription in vitro. Nucleic Acids Res 1981 2.46
14 c-Myc mediates activation of the cad promoter via a post-RNA polymerase II recruitment mechanism. J Biol Chem 2001 2.36
15 Transcriptional regulation of mouse dihydrofolate reductase in the cell cycle. J Biol Chem 1985 2.31
16 Opposite-strand RNAs from the 5' flanking region of the mouse dihydrofolate reductase gene. Proc Natl Acad Sci U S A 1985 2.30
17 A model for transcription termination suggested by studies on the trp attenuator in vitro using base analogs. Cell 1980 2.30
18 Heterogeneity at the 5' termini of mouse dihydrofolate reductase mRNAs. Evidence for multiple promoter regions. J Biol Chem 1985 2.29
19 Introduction to the E2F family: protein structure and gene regulation. Curr Top Microbiol Immunol 1996 2.24
20 Coexamination of site-specific transcription factor binding and promoter activity in living cells. Mol Cell Biol 1999 2.09
21 An E-box-mediated increase in cad transcription at the G1/S-phase boundary is suppressed by inhibitory c-Myc mutants. Mol Cell Biol 1995 2.08
22 Effects of NusA protein on transcription termination in the tryptophan operon of Escherichia coli. Cell 1982 1.96
23 In vitro transcription and delimitation of promoter elements of the murine dihydrofolate reductase gene. Mol Cell Biol 1986 1.64
24 Direct examination of histone acetylation on Myc target genes using chromatin immunoprecipitation. J Biol Chem 2000 1.54
25 Expression profiling and identification of novel genes in hepatocellular carcinomas. Oncogene 2001 1.50
26 Murine dihydrofolate reductase transcripts through the cell cycle. Mol Cell Biol 1986 1.43
27 Site-specific initiation of transcription by RNA polymerase II. Proc Soc Exp Biol Med 1993 1.43
28 E2F-mediated growth regulation requires transcription factor cooperation. J Biol Chem 1997 1.36
29 Context-dependent transcriptional regulation. J Biol Chem 1999 1.36
30 The HIP1 initiator element plays a role in determining the in vitro requirement of the dihydrofolate reductase gene promoter for the C-terminal domain of RNA polymerase II. Mol Cell Biol 1992 1.35
31 The chromatin structure of the dual c-myc promoter P1/P2 is regulated by separate elements. J Biol Chem 2001 1.32
32 Start site selection at the TATA-less carbamoyl-phosphate synthase (glutamine-hydrolyzing)/aspartate carbamoyltransferase/dihydroorotase promoter. J Biol Chem 1994 1.30
33 Transcriptional regulation of the dihydrofolate reductase gene. Bioessays 1996 1.29
34 Position-dependent transcriptional regulation of the murine dihydrofolate reductase promoter by the E2F transactivation domain. Mol Cell Biol 1997 1.26
35 Cloning, chromosomal location, and characterization of mouse E2F1. Mol Cell Biol 1994 1.25
36 Activation of the murine dihydrofolate reductase promoter by E2F1. A requirement for CBP recruitment. J Biol Chem 1999 1.23
37 Exogenous E2F expression is growth inhibitory before, during, and after cellular transformation. Oncogene 2000 1.14
38 Ultrastructural features of minute chromosomes in a methotrexate-resistant mouse 3T3 cell line. Proc Natl Acad Sci U S A 1985 1.14
39 Identification of target genes of oncogenic transcription factors. Proc Soc Exp Biol Med 1999 1.07
40 An inhibitory Raf-1 mutant suppresses expression of a subset of v-raf-activated genes. J Biol Chem 1993 1.03
41 ZNF217, a candidate breast cancer oncogene amplified at 20q13, regulates expression of the ErbB3 receptor tyrosine kinase in breast cancer cells. Oncogene 2010 0.99
42 Transcriptional regulation of the dihydrofolate reductase/rep-3 locus. Crit Rev Eukaryot Gene Expr 1994 0.97
43 Direct recruitment of N-myc to target gene promoters. Mol Carcinog 2000 0.95
44 The bidirectionally transcribed dihydrofolate reductase and rep-3a promoters are growth regulated by distinct mechanisms. Cell Growth Differ 1995 0.94
45 Identification of a new promoter upstream of the murine dihydrofolate reductase gene. Mol Cell Biol 1989 0.92
46 Inappropriate transcription from the 5' end of the murine dihydrofolate reductase gene masks transcriptional regulation. Nucleic Acids Res 1994 0.90
47 No effect of loss of E2F1 on liver regeneration or hepatocarcinogenesis in C57BL/6J or C3H/HeJ mice. Mol Carcinog 1999 0.87
48 v-Raf activates transcription of growth-responsive promoters via GC-rich sequences that bind the transcription factor Sp1. Cell Growth Differ 1995 0.86
49 CAD, a c-Myc target gene, is not deregulated in Burkitt's lymphoma cell lines. Mol Carcinog 2000 0.86
50 Strain-dependent differences in DNA synthesis and gene expression in the regenerating livers of CB57BL/6J and C3H/HeJ mice. Mol Carcinog 1995 0.83
51 krox 20 messenger RNA and protein expression in the adult central nervous system. Brain Res Mol Brain Res 1992 0.82
52 Effects of DNA base analogs on transcription termination at the tryptophan operon attenuator of EScherichia coli. Proc Natl Acad Sci U S A 1982 0.82
53 Identification of cis-acting elements that can obviate a requirement for the C-terminal domain of RNA polymerase II. J Biol Chem 1995 0.80
54 Identification of the serum-responsive transcription initiation site of the zinc finger gene Krox-20. Mol Cell Biol 1990 0.79
55 Heat sensitivity and Sp1 activation of complex formation at the Syrian hamster carbamoyl-phosphate synthase (glutamine-hydrolyzing)/aspartate carbamoyltransferase/dihydroorotase promoter in vitro. J Biol Chem 1992 0.78
56 Cell cycle analysis of Krox-20, c-fos, and JE expression in proliferating NIH3T3 fibroblasts. Cell Growth Differ 1991 0.78
57 Effects of gentamicin on trypsin, chymotrypsin, and collagenase. J Infect Dis 1978 0.76
58 Characterization of the 3' untranslated region of mouse E2F1 mRNA. Gene 1998 0.75
59 A re-examination of the distributions of octopamine and phenylethanolamine in the aplysia nervous system. J Neurochem 1978 0.75