Published in Mol Cell Biol on January 01, 1996
Targeted disruption of the PU.1 gene results in multiple hematopoietic abnormalities. EMBO J (1996) 5.17
Negative cross-talk between hematopoietic regulators: GATA proteins repress PU.1. Proc Natl Acad Sci U S A (1999) 3.04
Direct interaction of hematopoietic transcription factors PU.1 and GATA-1: functional antagonism in erythroid cells. Genes Dev (1999) 3.02
PU.1 induces myeloid lineage commitment in multipotent hematopoietic progenitors. Genes Dev (1998) 2.69
Multiple functional domains of AML1: PU.1 and C/EBPalpha synergize with different regions of AML1. Mol Cell Biol (1998) 1.69
PU.1 and pRB interact and cooperate to repress GATA-1 and block erythroid differentiation. Mol Cell Biol (2003) 1.42
BSAP can repress enhancer activity by targeting PU.1 function. Mol Cell Biol (2000) 1.12
PU.1 can participate in an active enhancer complex without its transcriptional activation domain. Proc Natl Acad Sci U S A (1997) 1.10
Gcn5 is required for PU.1-dependent IL-9 induction in Th9 cells. J Immunol (2012) 1.10
Characterization of NERF, a novel transcription factor related to the Ets factor ELF-1. Mol Cell Biol (1996) 1.09
Interleukin-3 stimulation of mcl-1 gene transcription involves activation of the PU.1 transcription factor through a p38 mitogen-activated protein kinase-dependent pathway. Mol Cell Biol (2003) 1.09
Control of myeloid-specific integrin alpha Mbeta 2 (CD11b/CD18) expression by cytokines is regulated by Stat3-dependent activation of PU.1. J Biol Chem (2002) 1.04
Inhibition of CBP-mediated protein acetylation by the Ets family oncoprotein PU.1. Mol Cell Biol (2002) 1.03
Do lampreys have lymphocytes? The Spi evidence. Proc Natl Acad Sci U S A (2000) 0.99
Normal myeloid development requires both the glutamine-rich transactivation domain and the PEST region of transcription factor PU.1 but not the potent acidic transactivation domain. Mol Cell Biol (1998) 0.97
The EICP22 protein of equine herpesvirus 1 physically interacts with the immediate-early protein and with itself to form dimers and higher-order complexes. J Virol (2000) 0.93
Evolution of hematopoiesis: Three members of the PU.1 transcription factor family in a cartilaginous fish, Raja eglanteria. Proc Natl Acad Sci U S A (2001) 0.92
Cytomegalovirus IE2 protein stimulates interleukin 1beta gene transcription via tethering to Spi-1/PU.1. Mol Cell Biol (1999) 0.89
The ETS family member ERM contains an alpha-helical acidic activation domain that contacts TAFII60. Nucleic Acids Res (1997) 0.86
Mi2beta shows chromatin enzyme specificity by erasing a DNase I-hypersensitive site established by ACF. J Biol Chem (2009) 0.76
Transcriptional Factor PU.1 Regulates Decidual C1q Expression in Early Pregnancy in Human. Front Immunol (2015) 0.75
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Different activation domains stimulate transcription from remote ('enhancer') and proximal ('promoter') positions. EMBO J (1992) 4.05
PU.1 recruits a second nuclear factor to a site important for immunoglobulin kappa 3' enhancer activity. Mol Cell Biol (1992) 3.32
Eukaryotic activators function during multiple steps of preinitiation complex assembly. Nature (1993) 3.16
Pattern of aromatic and hydrophobic amino acids critical for one of two subdomains of the VP16 transcriptional activator. Proc Natl Acad Sci U S A (1993) 3.02
The activation domain of transcription factor PU.1 binds the retinoblastoma (RB) protein and the transcription factor TFIID in vitro: RB shows sequence similarity to TFIID and TFIIB. Proc Natl Acad Sci U S A (1993) 2.90
The macrophage transcription factor PU.1 directs tissue-specific expression of the macrophage colony-stimulating factor receptor. Mol Cell Biol (1994) 2.69
The proto-oncogene PU.1 regulates expression of the myeloid-specific CD11b promoter. J Biol Chem (1993) 2.20
The Epstein-Barr virus R transactivator (Rta) contains a complex, potent activation domain with properties different from those of VP16. J Virol (1992) 2.19
PU.1 is a component of a multiprotein complex which binds an essential site in the murine immunoglobulin lambda 2-4 enhancer. Mol Cell Biol (1993) 2.08
Effect of PU.1 phosphorylation on interaction with NF-EM5 and transcriptional activation. Science (1993) 2.06
Structure(?) and function of acidic transcription activators. Cell (1993) 1.99
Regulation of lymphoid-specific immunoglobulin mu heavy chain gene enhancer by ETS-domain proteins. Science (1993) 1.96
Mouse beta-globin DNA-binding protein B1 is identical to a proto-oncogene, the transcription factor Spi-1/PU.1, and is restricted in expression to hematopoietic cells and the testis. Mol Cell Biol (1993) 1.80
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Characterization of the ets oncogene family member, fli-1. J Biol Chem (1993) 1.57
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Ets-related protein PU.1 regulates expression of the immunoglobulin J-chain gene through a novel Ets-binding element. Genes Dev (1993) 1.37
Cell-specific expression of the macrophage scavenger receptor gene is dependent on PU.1 and a composite AP-1/ets motif. Mol Cell Biol (1994) 1.37
Monocyte expression of the human prointerleukin 1 beta gene (IL1B) is dependent on promoter sequences which bind the hematopoietic transcription factor Spi-1/PU.1. Mol Cell Biol (1995) 1.26
PU.1 and GATA: components of a mast cell-specific interleukin 4 intronic enhancer. Proc Natl Acad Sci U S A (1994) 1.24
Restriction of interferon gamma responsiveness and basal expression of the myeloid human Fc gamma R1b gene is mediated by a functional PU.1 site and a transcription initiator consensus. J Exp Med (1994) 1.22
Multiple motifs regulate the B-cell-specific promoter of the B29 gene. Proc Natl Acad Sci U S A (1993) 1.06
PU.1 and an HLH family member contribute to the myeloid-specific transcription of the Fc gamma RIIIA promoter. EMBO J (1994) 1.04
The PU.1/Spi-1 proto-oncogene is a transcriptional regulator of a lentivirus promoter. J Virol (1993) 1.01
The macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogene. Cell (1990) 8.00
Turning blood into brain: cells bearing neuronal antigens generated in vivo from bone marrow. Science (2000) 6.16
Targeted disruption of the PU.1 gene results in multiple hematopoietic abnormalities. EMBO J (1996) 5.17
The ETS-domain: a new DNA-binding motif that recognizes a purine-rich core DNA sequence. Genes Dev (1990) 4.46
PU.1 recruits a second nuclear factor to a site important for immunoglobulin kappa 3' enhancer activity. Mol Cell Biol (1992) 3.32
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Ras-mediated phosphorylation of a conserved threonine residue enhances the transactivation activities of c-Ets1 and c-Ets2. Mol Cell Biol (1996) 2.79
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The proto-oncogene PU.1 regulates expression of the myeloid-specific CD11b promoter. J Biol Chem (1993) 2.20
Defective trophoblast function in mice with a targeted mutation of Ets2. Genes Dev (1998) 2.19
A new pattern for helix-turn-helix recognition revealed by the PU.1 ETS-domain-DNA complex. Nature (1996) 2.17
Effect of PU.1 phosphorylation on interaction with NF-EM5 and transcriptional activation. Science (1993) 2.06
Identification and functional analysis of mutations in the hypocretin (orexin) genes of narcoleptic canines. Genome Res (2001) 1.59
Characterization of the ets oncogene family member, fli-1. J Biol Chem (1993) 1.57
Tracts of high or low sequence divergence in the mouse major histocompatibility complex. EMBO J (1984) 1.42
Transcription factor PU.1 is necessary for development of thymic and myeloid progenitor-derived dendritic cells. J Immunol (2000) 1.42
Differentiation of the mononuclear phagocyte system during mouse embryogenesis: the role of transcription factor PU.1. Blood (1999) 1.41
Myeloperoxidase polymorphism is associated with gender specific risk for Alzheimer's disease. Exp Neurol (1999) 1.36
Myeloid development is selectively disrupted in PU.1 null mice. Blood (1998) 1.33
Regulation of the PU.1 gene by distal elements. Blood (2001) 1.28
Mesenchymal cells engulf and clear apoptotic footplate cells in macrophageless PU.1 null mouse embryos. Development (2000) 1.28
Characterization of gamma-aminobutyric acid receptor GABAB(1e), a GABAB(1) splice variant encoding a truncated receptor. J Biol Chem (2000) 1.18
Neutrophils deficient in PU.1 do not terminally differentiate or become functionally competent. Blood (1998) 1.14
Nephroblastoma overexpressed gene (NOV) codes for a growth factor that induces protein tyrosine phosphorylation. Gene (1999) 1.13
Identification of a nuclear factor that binds to a conserved sequence of the I-A beta gene. J Immunol (1988) 1.12
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PU.1 but not ets-2 is essential for macrophage development from embryonic stem cells. Blood (1996) 1.11
ADAMTS9, a novel member of the ADAM-TS/ metallospondin gene family. Genomics (2000) 1.10
Immunomodulation in type 1 diabetes by NBI-6024, an altered peptide ligand of the insulin B epitope. Scand J Immunol (2006) 1.09
Localization of agonist- and antagonist-binding domains of human corticotropin-releasing factor receptors. Mol Endocrinol (1997) 1.09
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DNA binding of the mouse class II major histocompatibility CCAAT factor depends on two components. Mol Cell Biol (1989) 1.06
Expression and activity of ADAMTS-5 in synovium. Eur J Biochem (2001) 1.05
The transcription factor PU.1 is involved in macrophage proliferation. J Exp Med (1996) 1.05
Stimulation of macrophages by lipopolysaccharide alters the phosphorylation state, conformation, and function of PU.1 via activation of casein kinase II. J Immunol (1997) 1.03
New insights on DNA recognition by ets proteins from the crystal structure of the PU.1 ETS domain-DNA complex. J Biol Chem (1996) 1.00
Transforming growth factor-beta enhances the M-CSF and GM-CSF-stimulated proliferation of macrophages. J Immunol (1992) 0.99
PU.1 and the granulocyte- and macrophage colony-stimulating factor receptors play distinct roles in late-stage myeloid cell differentiation. Blood (1999) 0.98
Commitment to the monocytic lineage occurs in the absence of the transcription factor PU.1. Blood (1999) 0.98
IFN-gamma induces the expression of the genes for MHC class II I-A beta and tumor necrosis factor through a protein kinase C-independent pathway. J Immunol (1991) 0.97
Cloning of a cDNA encoding a novel interleukin-1 receptor related protein (IL 1R-rp2). J Neuroimmunol (1996) 0.95
The copper transport protein Atox1 promotes neuronal survival. J Biol Chem (2000) 0.94
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Experimental autoimmune encephalomyelitis develops in CC chemokine receptor 7-deficient mice with altered T-cell responses. Scand J Immunol (2006) 0.94
Repression of major histocompatibility complex I-A beta gene expression by dbpA and dbpB (mYB-1) proteins. Mol Cell Biol (1995) 0.94
Expression and characterization of a putative high affinity human soluble leptin receptor. Endocrinology (1997) 0.91
Mutation analysis of the Pip interaction domain reveals critical residues for protein-protein interactions. Proc Natl Acad Sci U S A (1999) 0.91
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Co-crystallization of an ETS domain (PU.1) in complex with DNA. Engineering the length of both protein and oligonucleotide. J Biol Chem (1995) 0.84
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Repression of I-A beta gene expression by the transcription factor PU.1. J Biol Chem (1995) 0.81
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Identification of a transcription factor that binds to the S box of the I-A beta gene of the major histocompatibility complex. Biochem J (1996) 0.77
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