Published in Ann Hum Genet on October 01, 1995
New susceptibility locus for rheumatoid arthritis suggested by a genome-wide linkage study. Proc Natl Acad Sci U S A (1998) 3.14
A genomewide screen of 345 families for autism-susceptibility loci. Am J Hum Genet (2003) 2.51
A genomewide screen for autism susceptibility loci. Am J Hum Genet (2001) 2.30
Estimating the additive genetic effect of the X chromosome. Genet Epidemiol (2005) 1.95
All LODs are not created equal. Am J Hum Genet (2000) 1.94
A genomewide scan for loci involved in attention-deficit/hyperactivity disorder. Am J Hum Genet (2002) 1.63
A whole-genome scan in 164 Dutch sib pairs with attention-deficit/hyperactivity disorder: suggestive evidence for linkage on chromosomes 7p and 15q. Am J Hum Genet (2003) 1.39
Genome-wide mapping of susceptibility to coronary artery disease identifies a novel replicated locus on chromosome 17. PLoS Genet (2006) 1.29
Statistics for nonparametric linkage analysis of X-linked traits in general pedigrees. Am J Hum Genet (2001) 0.80
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Prognosis in HIV-1 infection predicted by the quantity of virus in plasma. Science (1996) 18.38
Plasma viral load and CD4+ lymphocytes as prognostic markers of HIV-1 infection. Ann Intern Med (1997) 16.44
Haplotype tagging for the identification of common disease genes. Nat Genet (2001) 11.27
A candidate for the cystic fibrosis locus isolated by selection for methylation-free islands. Nature (1987) 7.88
Localization of cystic fibrosis locus to human chromosome 7cen-q22. Nature (1985) 7.77
A genome-wide search for human type 1 diabetes susceptibility genes. Nature (1994) 7.13
Quantitation of HIV-1 RNA in plasma predicts outcome after seroconversion. Ann Intern Med (1995) 6.90
Chromosome-specific microsatellite sets for fluorescence-based, semi-automated genome mapping. Nat Genet (1994) 4.45
Maternal viral load, zidovudine treatment, and the risk of transmission of human immunodeficiency virus type 1 from mother to infant. Pediatric AIDS Clinical Trials Group Protocol 076 Study Group. N Engl J Med (1996) 4.44
The genetically isolated populations of Finland and sardinia may not be a panacea for linkage disequilibrium mapping of common disease genes. Nat Genet (2000) 3.92
Susceptibility to human type 1 diabetes at IDDM2 is determined by tandem repeat variation at the insulin gene minisatellite locus. Nat Genet (1995) 3.87
Genetic analysis of autoimmune disease. Cell (1996) 3.87
Linkage of cystic fibrosis to two tightly linked DNA markers: joint report from a collaborative study. Am J Hum Genet (1986) 3.83
Genetic control of autoimmune diabetes in the NOD mouse. Annu Rev Immunol (1995) 3.71
Insulin expression in human thymus is modulated by INS VNTR alleles at the IDDM2 locus. Nat Genet (1997) 3.62
Towards construction of a high resolution map of the mouse genome using PCR-analysed microsatellites. Nucleic Acids Res (1990) 3.59
Analysis of 17 autoimmune disease-associated variants in type 1 diabetes identifies 6q23/TNFAIP3 as a susceptibility locus. Genes Immun (2008) 3.48
The CTLA-4 gene region of chromosome 2q33 is linked to, and associated with, type 1 diabetes. Belgian Diabetes Registry. Hum Mol Genet (1996) 3.37
Rapid and precise quantification of HIV-1 RNA in plasma using a branched DNA signal amplification assay. J Acquir Immune Defic Syndr Hum Retrovirol (1995) 3.23
Encapsulating peritoneal sclerosis: definition, etiology, diagnosis, and treatment. International Society for Peritoneal Dialysis Ad Hoc Committee on Ultrafiltration Management in Peritoneal Dialysis. Perit Dial Int (2000) 3.20
The origins of two-state spontaneous membrane potential fluctuations of neostriatal spiny neurons. J Neurosci (1996) 3.20
Integrating case-control and TDT studies. Ann Hum Genet (2005) 3.19
Towards fully automated genome-wide polymorphism screening. Nat Genet (1995) 3.13
Patterns of polymorphism and linkage disequilibrium for cystic fibrosis. Genomics (1987) 3.03
Two-locus maximum lod score analysis of a multifactorial trait: joint consideration of IDDM2 and IDDM4 with IDDM1 in type 1 diabetes. Am J Hum Genet (1995) 3.02
Mapping of mutation causing Friedreich's ataxia to human chromosome 9. Nature (1988) 2.96
Genetic influences on F cells and other hematologic variables: a twin heritability study. Blood (2000) 2.95
A search for type 1 diabetes susceptibility genes in families from the United Kingdom. Nat Genet (1998) 2.85
Type 1 diabetes in mice is linked to the interleukin-1 receptor and Lsh/Ity/Bcg genes on chromosome 1. Nature (1991) 2.84
Adult peritoneal dialysis-related peritonitis treatment recommendations: 2000 update. Perit Dial Int (2001) 2.81
Linkage of the angiotensinogen gene to essential hypertension. N Engl J Med (1994) 2.80
CD226 Gly307Ser association with multiple autoimmune diseases. Genes Immun (2008) 2.76
Hopping hotspots: global shifts in marine biodiversity. Science (2008) 2.68
Intracortical facilitation and inhibition after transcranial magnetic stimulation in conscious humans. J Physiol (1997) 2.65
Application of branched DNA signal amplification to monitor human immunodeficiency virus type 1 burden in human plasma. J Infect Dis (1994) 2.60
Measured haplotype analysis of the angiotensin-I converting enzyme gene. Hum Mol Genet (1998) 2.53
Identification of the sources of error in allele frequency estimations from pooled DNA indicates an optimal experimental design. Ann Hum Genet (2002) 2.51
Association of the INS VNTR with size at birth. ALSPAC Study Team. Avon Longitudinal Study of Pregnancy and Childhood. Nat Genet (1998) 2.49
Peritoneal dialysis-related peritonitis treatment recommendations: 1996 update. Perit Dial Int (1997) 2.47
A correlation between the relative predisposition of MHC class II alleles to type 1 diabetes and the structure of their proteins. Hum Mol Genet (2001) 2.43
Isolation of a further anonymous informative DNA sequence from chromosome seven closely linked to cystic fibrosis. Nucleic Acids Res (1986) 2.34
Serial changes in trunk muscle performance after posterior lumbar surgery. Spine (Phila Pa 1976) (1999) 2.25
Unbiased application of the transmission/disequilibrium test to multilocus haplotypes. Am J Hum Genet (2000) 2.22
Strategies in complex disease mapping. Curr Opin Genet Dev (2000) 2.20
Aspartic acid at position 57 of the HLA-DQ beta chain protects against type I diabetes: a family study. Proc Natl Acad Sci U S A (1988) 2.19
The predisposition to type 1 diabetes linked to the human leukocyte antigen complex includes at least one non-class II gene. Am J Hum Genet (1999) 2.17
Beta 2-microglobulin-deficient NOD mice do not develop insulitis or diabetes. Diabetes (1994) 2.16
The MHC haplotype project: a resource for HLA-linked association studies. Tissue Antigens (2002) 2.16
Physical and genetic analysis of cosmids from the vicinity of the cystic fibrosis locus. Nucleic Acids Res (1987) 2.16
Linkage of COL1A2 collagen gene to cystic fibrosis, and its clinical implications. Lancet (1985) 2.14
Cost-effective analysis of candidate genes using htSNPs: a staged approach. Genes Immun (2004) 2.07
Unique features of the CAG repeats in Machado-Joseph disease. Nat Genet (1995) 2.06
Microsatellites for linkage analysis of genetic traits. Trends Genet (1992) 2.05
Predisposing locus for Alzheimer's disease on chromosome 21. Lancet (1989) 1.99
Cloning of a novel member of the low-density lipoprotein receptor family. Gene (1998) 1.97
Identification of multiple quantitative trait loci linked to prion disease incubation period in mice. Proc Natl Acad Sci U S A (2001) 1.96
Confirmation of HLA class II independent type 1 diabetes associations in the major histocompatibility complex including HLA-B and HLA-A. Diabetes Obes Metab (2009) 1.94
Isolation and characterization of LRP6, a novel member of the low density lipoprotein receptor gene family. Biochem Biophys Res Commun (1998) 1.93
No association of multiple type 2 diabetes loci with type 1 diabetes. Diabetologia (2009) 1.92
Allelic variation in the DR subregion of the human major histocompatibility complex. Proc Natl Acad Sci U S A (1987) 1.92
Linkage and association of insulin gene VNTR regulatory polymorphism with polycystic ovary syndrome. Lancet (1997) 1.91
A single amino acid substitution in the cyclin D binding domain of the infected cell protein no. 0 abrogates the neuroinvasiveness of herpes simplex virus without affecting its ability to replicate. Proc Natl Acad Sci U S A (1999) 1.90
Electrocardiographic measures of left ventricular hypertrophy show greater heritability than echocardiographic left ventricular mass. Eur Heart J (2002) 1.89
Acute hydrothorax in continuous ambulatory peritoneal dialysis--a collaborative study of 161 centers. Am J Nephrol (1989) 1.88
Evidence of association of the ecNOS gene polymorphism with plasma NO metabolite levels in humans. Biochem Biophys Res Commun (1998) 1.86
Reduced heat resistance of mutant spores after cloning and mutagenesis of the Bacillus subtilis gene encoding penicillin-binding protein 5. J Bacteriol (1986) 1.83
Additional microsatellite markers for mouse genome mapping. Mamm Genome (1991) 1.79
Cloning and expression in Escherichia coli of the insecticidal delta-endotoxin gene of Bacillus thuringiensis var. israelensis. FEBS Lett (1984) 1.77
Indirect cystic fibrosis carrier detection. Lancet (1987) 1.76
Major factors influencing linkage disequilibrium by analysis of different chromosome regions in distinct populations: demography, chromosome recombination frequency and selection. Hum Mol Genet (2000) 1.76
Bacillus thuringiensis var. israelensis delta-endotoxin. Cloning and expression of the toxin in sporogenic and asporogenic strains of Bacillus subtilis. J Mol Biol (1986) 1.74
Genome-wide association study of body mass index in 23 000 individuals with and without asthma. Clin Exp Allergy (2013) 1.74
Cloning of a pH-sensitive K+ channel possessing two transmembrane segments. Nature (1994) 1.73
Evaluation of single nucleotide polymorphism typing with invader on PCR amplicons and its automation. Genome Res (2000) 1.71
Genetic homogeneity at the Friedreich ataxia locus on chromosome 9. Am J Hum Genet (1989) 1.66
Reversal of anemia by erythropoietin therapy retards the progression of chronic renal failure, especially in nondiabetic patients. Nephron (1997) 1.63
First-trimester prenatal diagnosis of cystic fibrosis with linked DNA probes. Lancet (1986) 1.61
The generation of a library of PCR-analyzed microsatellite variants for genetic mapping of the mouse genome. Genomics (1991) 1.61
Linkage disequilibrium between cystic fibrosis and linked DNA polymorphisms in Italian families: a collaborative study. Am J Hum Genet (1988) 1.60
Dependence of GABAergic synaptic areas on the interneuron type and target size. J Neurosci (2000) 1.60
Identification of a feline immunodeficiency virus gene which is essential for cell-free virus infectivity. J Virol (1992) 1.59
New genetic loci that control susceptibility and symptoms of experimental allergic encephalomyelitis in inbred mice. J Immunol (1998) 1.58
The HLA-DPB1--associated component of the IDDM1 and its relationship to the major loci HLA-DQB1, -DQA1, and -DRB1. Diabetes (2001) 1.58
Localization of the malignant hyperthermia susceptibility locus to human chromosome 19q12-13.2. Nature (1990) 1.57
Analysis of 55 autoimmune disease and type II diabetes loci: further confirmation of chromosomes 4q27, 12q13.2 and 12q24.13 as type I diabetes loci, and support for a new locus, 12q13.3-q14.1. Genes Immun (2009) 1.53
Adaptation of the extended transmission/disequilibrium test to distinguish disease associations of multiple loci: the Conditional Extended Transmission/Disequilibrium Test. Ann Hum Genet (2000) 1.53
Genotype effects and epistasis in type 1 diabetes and HLA-DQ trans dimer associations with disease. Genes Immun (2004) 1.53
Mapping of a major genetic modifier of embryonic lethality in TGF beta 1 knockout mice. Nat Genet (1997) 1.51
A male-female bias in type 1 diabetes and linkage to chromosome Xp in MHC HLA-DR3-positive patients. Nat Genet (1998) 1.50
Sporadic--but not variant--Creutzfeldt-Jakob disease is associated with polymorphisms upstream of PRNP exon 1. Am J Hum Genet (2001) 1.50
Resistance alleles at two non-major histocompatibility complex-linked insulin-dependent diabetes loci on chromosome 3, Idd3 and Idd10, protect nonobese diabetic mice from diabetes. J Exp Med (1994) 1.49
Seven regions of the genome show evidence of linkage to type 1 diabetes in a consensus analysis of 767 multiplex families. Am J Hum Genet (2001) 1.49
Clinical trial of oral malodor treatment in patients with periodontal diseases. J Periodontal Res (2011) 1.48
Cyclic nature of poly(3-hydroxyalkanoate) metabolism in Alcaligenes eutrophus. FEMS Microbiol Lett (1990) 1.48
Impact of lipoprotein(a) levels and apolipoprotein(a) isoform size on risk of coronary heart disease. J Intern Med (2014) 1.48