Published in Genes Immun on December 25, 2008
Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes. Nat Genet (2009) 16.53
A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus. Nat Genet (2009) 5.75
Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20. Nat Genet (2009) 4.97
Pervasive sharing of genetic effects in autoimmune disease. PLoS Genet (2011) 4.42
Inhibition of NF-kappaB signaling by A20 through disruption of ubiquitin enzyme complexes. Science (2010) 4.03
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A genome-wide meta-analysis of six type 1 diabetes cohorts identifies multiple associated loci. PLoS Genet (2011) 1.60
Statistical colocalization of genetic risk variants for related autoimmune diseases in the context of common controls. Nat Genet (2015) 1.56
Analysis of 55 autoimmune disease and type II diabetes loci: further confirmation of chromosomes 4q27, 12q13.2 and 12q24.13 as type I diabetes loci, and support for a new locus, 12q13.3-q14.1. Genes Immun (2009) 1.53
African-derived genetic polymorphisms in TNFAIP3 mediate risk for autoimmunity. J Immunol (2010) 1.52
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Sequencing of TNFAIP3 and association of variants with multiple autoimmune diseases. Genes Immun (2011) 1.24
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Genetic analysis of adult-onset autoimmune diabetes. Diabetes (2011) 1.22
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Loss-of-function mutations in TNFAIP3 leading to A20 haploinsufficiency cause an early-onset autoinflammatory disease. Nat Genet (2015) 1.13
TNFAIP3 gene polymorphisms are associated with response to TNF blockade in psoriasis. J Invest Dermatol (2011) 1.10
Evidence for STAT4 as a common autoimmune gene: rs7574865 is associated with colonic Crohn's disease and early disease onset. PLoS One (2010) 1.06
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Non-synonymous variant (Gly307Ser) in CD226 is associated with susceptibility to multiple autoimmune diseases. Rheumatology (Oxford) (2010) 1.01
A non-synonymous SNP within membrane metalloendopeptidase-like 1 (MMEL1) is associated with multiple sclerosis. Genes Immun (2010) 0.95
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Genetic susceptibility to lupus: the biological basis of genetic risk found in B cell signaling pathways. J Leukoc Biol (2012) 0.94
TNFAIP3 gene polymorphisms confer risk for Behcet's disease in a Chinese Han population. Hum Genet (2012) 0.93
Subtype specific genetic associations for juvenile idiopathic arthritis: ERAP1 with the enthesitis related arthritis subtype and IL23R with juvenile psoriatic arthritis. Arthritis Res Ther (2011) 0.93
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Proficiency testing of human leukocyte antigen-DR and human leukocyte antigen-DQ genetic risk assessment for type 1 diabetes using dried blood spots. J Diabetes Sci Technol (2010) 0.89
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Association of single-nucleotide polymorphisms in the STAT3 gene with autoimmune thyroid disease in Chinese individuals. Funct Integr Genomics (2013) 0.86
Identification of a functional variant in the KIF5A-CYP27B1-METTL1-FAM119B locus associated with multiple sclerosis. J Med Genet (2012) 0.85
A20 restricts wnt signaling in intestinal epithelial cells and suppresses colon carcinogenesis. PLoS One (2013) 0.84
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Let-7 miRNAs Modulate the Activation of NF-κB by Targeting TNFAIP3 and Are Involved in the Pathogenesis of Lupus Nephritis. PLoS One (2015) 0.83
Endoplasmic reticulum aminopeptidase-1 functions regulate key aspects of the innate immune response. PLoS One (2013) 0.82
A failure of TNFAIP3 negative regulation maintains sustained NF-κB activation in Sjögren's syndrome. Histochem Cell Biol (2011) 0.81
NF-κB and Rheumatoid Arthritis: Will Understanding Genetic Risk Lead to a Therapeutic Reward? For Immunopathol Dis Therap (2013) 0.79
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Genomic correlates of variability in immune response to an oral cholera vaccine. Eur J Hum Genet (2012) 0.78
Frequent down regulation of the tumor suppressor gene a20 in multiple myeloma. PLoS One (2015) 0.78
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STAT4 polymorphisms and diabetes risk: a meta-analysis with 18931 patients and 23833 controls. Int J Clin Exp Med (2015) 0.77
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STAT4 rs7574865 polymorphism contributes to the risk of type 1 diabetes: a meta analysis. Int J Clin Exp Med (2015) 0.77
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Autoimmune disease-associated variants of extracellular endoplasmic reticulum aminopeptidase 1 induce altered innate immune responses by human immune cells. J Innate Immun (2015) 0.76
A20 deficiency sensitizes pancreatic beta cells to cytokine-induced apoptosis in vitro but does not influence type 1 diabetes development in vivo. Cell Death Dis (2015) 0.76
Downstream activation of NF-κB in the EDA-A1/EDAR signalling in Sjögren's syndrome and its regulation by the ubiquitin-editing enzyme A20. Clin Exp Immunol (2016) 0.75
Type 1 Diabetes Candidate Genes Linked to Pancreatic Islet Cell Inflammation and Beta-Cell Apoptosis. Genes (Basel) (2017) 0.75
Functional effect of polymorphisms in the promoter of TNFAIP3 (A20) in acute pancreatitis in the Han Chinese population. PLoS One (2014) 0.75
Identifying Causal Genes at the Multiple Sclerosis Associated Region 6q23 Using Capture Hi-C. PLoS One (2016) 0.75
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Autoimmune risk variants in ERAP2 are associated with gene-expression levels in thymus. Genes Immun (2016) 0.75
The Association Between Genetic Polymorphism rs703842 in CYP27B1 and Multiple Sclerosis: A Meta-Analysis. Medicine (Baltimore) (2016) 0.75
IL12RB2 gene is associated with the age of type 1 diabetes onset in Croatian family Trios. PLoS One (2012) 0.75
A20 targets caspase-8 and FADD to protect HTLV-I-infected cells. Leukemia (2015) 0.75
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Intracellular B Lymphocyte Signalling and the Regulation of Humoral Immunity and Autoimmunity. Clin Rev Allergy Immunol (2017) 0.75
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