Published in RNA on December 01, 1995
A prokaryotic-like mode of cytoplasmic eukaryotic ribosome binding to the initiation codon during internal translation initiation of hepatitis C and classical swine fever virus RNAs. Genes Dev (1998) 7.72
Switch from translation to RNA replication in a positive-stranded RNA virus. Genes Dev (1998) 4.59
The requirement for eukaryotic initiation factor 4A (elF4A) in translation is in direct proportion to the degree of mRNA 5' secondary structure. RNA (2001) 3.65
Automatic detection of conserved RNA structure elements in complete RNA virus genomes. Nucleic Acids Res (1998) 3.18
Cap-independent polysomal association of natural mRNAs encoding c-myc, BiP, and eIF4G conferred by internal ribosome entry sites. RNA (1998) 3.00
A cell cycle-dependent protein serves as a template-specific translation initiation factor. Genes Dev (2000) 2.84
A 9-nt segment of a cellular mRNA can function as an internal ribosome entry site (IRES) and when present in linked multiple copies greatly enhances IRES activity. Proc Natl Acad Sci U S A (2000) 2.66
Translational control of viral gene expression in eukaryotes. Microbiol Mol Biol Rev (2000) 2.63
Two independent internal ribosome entry sites are involved in translation initiation of vascular endothelial growth factor mRNA. Mol Cell Biol (1998) 2.59
unr, a cellular cytoplasmic RNA-binding protein with five cold-shock domains, is required for internal initiation of translation of human rhinovirus RNA. Genes Dev (1999) 2.59
Physical association of eukaryotic initiation factor 4G (eIF4G) with eIF4A strongly enhances binding of eIF4G to the internal ribosomal entry site of encephalomyocarditis virus and is required for internal initiation of translation. Mol Cell Biol (2000) 2.58
Posttranscriptional control of gene expression in yeast. Microbiol Mol Biol Rev (1998) 2.54
Eukaryotic translation initiation factor 4GI is a cellular target for NS1 protein, a translational activator of influenza virus. Mol Cell Biol (2000) 2.48
The La antigen binds 5' noncoding region of the hepatitis C virus RNA in the context of the initiator AUG codon and stimulates internal ribosome entry site-mediated translation. Proc Natl Acad Sci U S A (1997) 2.43
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c-Myc protein synthesis is initiated from the internal ribosome entry segment during apoptosis. Mol Cell Biol (2000) 2.03
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Sendai virus Y proteins are initiated by a ribosomal shunt. Mol Cell Biol (1998) 1.63
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Functional involvement of polypyrimidine tract-binding protein in translation initiation complexes with the internal ribosome entry site of foot-and-mouth disease virus. J Virol (1997) 1.56
Cell-specific proteins regulate viral RNA translation and virus-induced disease. EMBO J (2001) 1.56
Direct functional interaction of initiation factor eIF4G with type 1 internal ribosomal entry sites. Proc Natl Acad Sci U S A (2009) 1.54
Ribosomal binding to the internal ribosomal entry site of classical swine fever virus. RNA (2000) 1.53
c-myc Internal ribosome entry site activity is developmentally controlled and subjected to a strong translational repression in adult transgenic mice. Mol Cell Biol (2001) 1.53
Interaction of the eIF4G initiation factor with the aphthovirus IRES is essential for internal translation initiation in vivo. RNA (2000) 1.51
5'-untranslated regions with multiple upstream AUG codons can support low-level translation via leaky scanning and reinitiation. Nucleic Acids Res (2004) 1.47
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Characterization of a novel RNA-binding region of eIF4GI critical for ribosomal scanning. EMBO J (2003) 1.43
Composition and arrangement of genes define the strength of IRES-driven translation in bicistronic mRNAs. Nucleic Acids Res (2001) 1.43
A ribosome-specialized translation initiation pathway is required for cap-dependent translation of vesicular stomatitis virus mRNAs. Proc Natl Acad Sci U S A (2012) 1.43
Structure and function of a cap-independent translation element that functions in either the 3' or the 5' untranslated region. RNA (2000) 1.42
Non-AUG-initiated internal translation of the L* protein of Theiler's virus and importance of this protein for viral persistence. J Virol (2002) 1.41
Eukaryotic initiation factors 4G and 4A mediate conformational changes downstream of the initiation codon of the encephalomyocarditis virus internal ribosomal entry site. Mol Cell Biol (2003) 1.40
Conserved structural motifs located in distal loops of aphthovirus internal ribosome entry site domain 3 are required for internal initiation of translation. J Virol (1997) 1.38
La autoantigen is required for the internal ribosome entry site-mediated translation of Coxsackievirus B3 RNA. Nucleic Acids Res (2002) 1.37
Unr is required in vivo for efficient initiation of translation from the internal ribosome entry sites of both rhinovirus and poliovirus. J Virol (2003) 1.36
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Internal ribosome entry site regulates translation of Kaposi's sarcoma-associated herpesvirus FLICE inhibitory protein. J Virol (2001) 1.34
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A general approach to the non-invasive imaging of transgenes using cis-linked herpes simplex virus thymidine kinase. Neoplasia (1999) 1.25
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Localization of a promoter in the putative internal ribosome entry site of the Saccharomyces cerevisiae TIF4631 gene. RNA (2004) 1.20
Revertant analysis of J-K mutations in the encephalomyocarditis virus internal ribosomal entry site detects an altered leader protein. J Virol (1996) 1.19
Cap-independent translation initiation in Xenopus oocytes. Nucleic Acids Res (1997) 1.19
Internal initiation drives the synthesis of Ure2 protein lacking the prion domain and affects [URE3] propagation in yeast cells. EMBO J (2003) 1.18
SARS coronavirus nsp1 protein induces template-dependent endonucleolytic cleavage of mRNAs: viral mRNAs are resistant to nsp1-induced RNA cleavage. PLoS Pathog (2011) 1.17
Back to basics: the untreated rabbit reticulocyte lysate as a competitive system to recapitulate cap/poly(A) synergy and the selective advantage of IRES-driven translation. Nucleic Acids Res (2007) 1.16
Evolutionary conservation of reactions in translation. Microbiol Mol Biol Rev (2002) 1.16
Rapamycin and wortmannin enhance replication of a defective encephalomyocarditis virus. J Virol (1998) 1.13
Absence of internal ribosome entry site-mediated tissue specificity in the translation of a bicistronic transgene. J Virol (1999) 1.13
Herpes simplex virus virion host shutoff protein requires a mammalian factor for efficient in vitro endoribonuclease activity. J Virol (2001) 1.13
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Sequential partially overlapping gene arrangement in the tricistronic S1 genome segments of avian reovirus and Nelson Bay reovirus: implications for translation initiation. J Virol (2002) 1.10
Internal ribosome entry site structural motifs conserved among mammalian fibroblast growth factor 1 alternatively spliced mRNAs. Mol Cell Biol (2004) 1.09
Polypyrimidine tract-binding protein stimulates the poliovirus IRES by modulating eIF4G binding. EMBO J (2010) 1.09
Molecular mechanisms of attenuation of the Sabin strain of poliovirus type 3. J Virol (2004) 1.08
Mechanisms of HCV survival in the host. Nat Rev Gastroenterol Hepatol (2009) 1.07
Novel fluorescence-based screen to identify small synthetic internal ribosome entry site elements. Mol Cell Biol (2001) 1.07
RNA structure-based ribosome recruitment: lessons from the Dicistroviridae intergenic region IRESes. RNA (2008) 1.07
A potential mechanism for selective control of cap-independent translation by a viral RNA sequence in cis and in trans. RNA (1999) 1.06
Translation initiation factor eIF4B interacts with a picornavirus internal ribosome entry site in both 48S and 80S initiation complexes independently of initiator AUG location. J Virol (1999) 1.06
Internal-ribosome-entry-site functional activity of the 3'-untranslated region of the mRNA for the beta subunit of mitochondrial H+-ATP synthase. Biochem J (2000) 1.05
Conserved nucleotides within the J domain of the encephalomyocarditis virus internal ribosome entry site are required for activity and for interaction with eIF4G. J Virol (2003) 1.03
Detailed analysis of the requirements of hepatitis A virus internal ribosome entry segment for the eukaryotic initiation factor complex eIF4F. J Virol (2001) 1.01
Altered interactions between stem-loop IV within the 5' noncoding region of coxsackievirus RNA and poly(rC) binding protein 2: effects on IRES-mediated translation and viral infectivity. Virology (2009) 1.01
In vivo and in vitro identification of structural and sequence elements of the human parechovirus 5' untranslated region required for internal initiation. J Virol (2000) 1.00
Discontinuous subgenomic RNA synthesis in arteriviruses is guided by an RNA hairpin structure located in the genomic leader region. J Virol (2005) 1.00
The role of 5'-leader length, secondary structure and PABP concentration on cap and poly(A) tail function during translation in Xenopus oocytes. Nucleic Acids Res (2000) 0.98
An internal ribosome entry site directs translation of the murine gammaherpesvirus 68 MK3 open reading frame. J Virol (2003) 0.98
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Complementarity between the mRNA 5' untranslated region and 18S ribosomal RNA can inhibit translation. RNA (2000) 0.97
The current status of vertebrate cellular mRNA IRESs. Cold Spring Harb Perspect Biol (2013) 0.97
miRNA repression of translation in vitro takes place during 43S ribosomal scanning. Nucleic Acids Res (2012) 0.96
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