Published in J Biol Chem on May 17, 1996
Arginine metabolism: nitric oxide and beyond. Biochem J (1998) 6.44
Amino acid transporters: roles in amino acid sensing and signalling in animal cells. Biochem J (2003) 1.84
Cellular ADMA: regulation and action. Pharmacol Res (2009) 1.42
Characteristics and function of cardiac mitochondrial nitric oxide synthase. J Physiol (2008) 1.20
Vascular endothelial dysfunction resulting from L-arginine deficiency in a patient with lysinuric protein intolerance. J Clin Invest (2001) 1.06
L-Arginine currents in rat cardiac ventricular myocytes. J Physiol (2007) 0.95
Deficient BH4 production via de novo and salvage pathways regulates NO responses to cytokines in adult cardiac myocytes. Am J Physiol Heart Circ Physiol (2008) 0.94
Cell signalling-mediating insulin increase of mRNA expression for cationic amino acid transporters-1 and -2 and membrane hyperpolarization in human umbilical vein endothelial cells. Pflugers Arch (2004) 0.90
Cationic amino acid transporters and Salmonella Typhimurium ArgT collectively regulate arginine availability towards intracellular Salmonella growth. PLoS One (2010) 0.85
Nitric oxide can acutely modulate its biosynthesis through a negative feedback mechanism on L-arginine transport in cardiac myocytes. Am J Physiol Cell Physiol (2010) 0.82
Activation of SphK1 by K6PC-5 Inhibits Oxygen-Glucose Deprivation/Reoxygenation-Induced Myocardial Cell Death. DNA Cell Biol (2015) 0.79
No effect of acute L-arginine supplementation on O₂ cost or exercise tolerance. Eur J Appl Physiol (2013) 0.78
Transmembrane signalling mechanisms regulating expression of cationic amino acid transporters and inducible nitric oxide synthase in rat vascular smooth muscle cells. Biochem J (1999) 0.77
Insulin increases mRNA abundance of the amino acid transporter SLC7A5/LAT1 via an mTORC1-dependent mechanism in skeletal muscle cells. Physiol Rep (2014) 0.77
Transsulfuration pathway thiols and methylated arginines: the Hunter Community Study. PLoS One (2013) 0.77
Cardiac L-arginine transport: the CAT is back. J Physiol (2007) 0.76
Insulin requires A1 adenosine receptors expression to reverse gestational diabetes-increased L-arginine transport in human umbilical vein endothelium. Purinergic Signal (2015) 0.76
Expression Profile of Cationic Amino Acid Transporters in Rats with Endotoxin-Induced Uveitis. Mediators Inflamm (2016) 0.75
Pressure overload-induced cardiac hypertrophy response requires janus kinase 2-histone deacetylase 2 signaling. Int J Mol Sci (2014) 0.75
Identification of two related pentapeptides from the brain with potent opiate agonist activity. Nature (1975) 10.33
A putative murine ecotropic retrovirus receptor gene encodes a multiple membrane-spanning protein and confers susceptibility to virus infection. Cell (1989) 7.64
Determination of therapeutic and toxic serum digoxin concentrations by radioimmunoassay. N Engl J Med (1969) 6.15
Intracellular heterogeneity in mitochondrial membrane potentials revealed by a J-aggregate-forming lipophilic cation JC-1. Proc Natl Acad Sci U S A (1991) 5.78
Transport of cationic amino acids by the mouse ecotropic retrovirus receptor. Nature (1991) 5.40
Internists' and surgeons' attitudes toward guns and firearm injury prevention. Ann Intern Med (1998) 5.15
Support for new policies to regulate firearms. Results of two national surveys. N Engl J Med (1998) 5.06
Retroviral entry mediated by receptor priming and low pH triggering of an envelope glycoprotein. Cell (2000) 4.88
Molecular cloning and functional expression of an inducible nitric oxide synthase from a murine macrophage cell line. J Biol Chem (1992) 4.88
Plasma digoxin concentrations in patients with atrial fibrillation. Br Med J (1970) 4.82
Targeted deletion of matrix metalloproteinase-9 attenuates left ventricular enlargement and collagen accumulation after experimental myocardial infarction. J Clin Invest (2000) 4.79
Biochemical evidence that patched is the Hedgehog receptor. Nature (1996) 4.53
J-aggregate formation of a carbocyanine as a quantitative fluorescent indicator of membrane potential. Biochemistry (1991) 4.11
Microsatellite instability in colorectal cancer: different mutator phenotypes and the principal involvement of hMLH1. Cancer Res (1998) 3.36
Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating beta-catenin/TCF signalling. Nat Genet (2000) 3.33
A meta-analytic review of research on hostility and physical health. Psychol Bull (1996) 3.27
Digitalis intoxication. A prospective clinical study with serum level correlations. N Engl J Med (1971) 3.27
Characterization of a human colon/lung carcinoma oncogene. Nature (1983) 3.26
Structure of a murine leukemia virus receptor-binding glycoprotein at 2.0 angstrom resolution. Science (1997) 3.13
The HL-60 transforming sequence: a ras oncogene coexisting with altered myc genes in hematopoietic tumors. Cell (1983) 3.00
Toll4 (TLR4) expression in cardiac myocytes in normal and failing myocardium. J Clin Invest (1999) 2.94
Altered expression of hMSH2 and hMLH1 in tumors with microsatellite instability and genetic alterations in mismatch repair genes. Cancer Res (1996) 2.89
Endothelial nitric oxide synthase targeting to caveolae. Specific interactions with caveolin isoforms in cardiac myocytes and endothelial cells. J Biol Chem (1996) 2.82
Envelope-binding domain in the cationic amino acid transporter determines the host range of ecotropic murine retroviruses. J Virol (1993) 2.77
Disruption of Ini1 leads to peri-implantation lethality and tumorigenesis in mice. Mol Cell Biol (2001) 2.76
Roles for the integrin VLA-4 and its counter receptor VCAM-1 in myogenesis. Cell (1992) 2.67
Digoxin intoxication: the relationship of clinical presentation to serum digoxin concentration. J Clin Invest (1970) 2.66
The distribution of methionine-enkephalin and leucine-enkephalin in the brain and peripheral tissues. Br J Pharmacol (1977) 2.59
The regulated expression of erythropoietin by two human hepatoma cell lines. Proc Natl Acad Sci U S A (1987) 2.51
Reversal of advanced digoxin intoxication with Fab fragments of digoxin-specific antibodies. N Engl J Med (1976) 2.49
Neuregulins promote survival and growth of cardiac myocytes. Persistence of ErbB2 and ErbB4 expression in neonatal and adult ventricular myocytes. J Biol Chem (1998) 2.42
Characterization of antibodies of high affinity and specificity for the digitalis glycoside digoxin. Biochemistry (1970) 2.39
Suspected low-grade glioma: is deferring treatment safe? Ann Neurol (1992) 2.37
Control of cardiac muscle cell function by an endogenous nitric oxide signaling system. Proc Natl Acad Sci U S A (1993) 2.32
The renal glomerulus of mice lacking s-laminin/laminin beta 2: nephrosis despite molecular compensation by laminin beta 1. Nat Genet (1995) 2.30
Receptors for polytropic and xenotropic mouse leukaemia viruses encoded by a single gene at Rmc1. Nat Genet (1999) 2.28
Nitric oxide synthase isozymes. Characterization, purification, molecular cloning, and functions. Hypertension (1994) 2.28
Enforced expression of the GATA-2 transcription factor blocks normal hematopoiesis. Blood (1999) 2.14
Stress-induced reversal of microRNA repression and mRNA P-body localization in human cells. Cold Spring Harb Symp Quant Biol (2006) 2.06
Maturation and maintenance of the neuromuscular synapse: genetic evidence for roles of the dystrophin--glycoprotein complex. Neuron (2000) 2.04
Medullomyoblastoma. A histologic, immunohistochemical, and ultrastructural study. Cancer (1984) 2.03
Nitric oxide and cardiac function. Circ Res (1996) 2.01
Digoxin therapy and mortality after myocardial infarction. Experience in the MILIS Study. N Engl J Med (1986) 1.96
Role of TLR-2 in the activation of nuclear factor kappaB by oxidative stress in cardiac myocytes. J Biol Chem (2000) 1.85
Mice deficient for the secreted glycoprotein SPARC/osteonectin/BM40 develop normally but show severe age-onset cataract formation and disruption of the lens. EMBO J (1998) 1.83
Cytokine-mediated apoptosis in cardiac myocytes: the role of inducible nitric oxide synthase induction and peroxynitrite generation. Circ Res (1999) 1.81
Nitric oxide-dependent parasympathetic signaling is due to activation of constitutive endothelial (type III) nitric oxide synthase in cardiac myocytes. J Biol Chem (1995) 1.80
Metabolic acidosis stimulates protein degradation in rat muscle by a glucocorticoid-dependent mechanism. J Clin Invest (1986) 1.78
Transferrin receptor in normal and neoplastic brain tissue: implications for brain-tumor immunotherapy. J Neurosurg (1990) 1.76
Microsatellite instability and mutation analysis of hMSH2 and hMLH1 in patients with sporadic, familial and hereditary colorectal cancer. Hum Mol Genet (1996) 1.76
Identification of a receptor-binding pocket on the envelope protein of friend murine leukemia virus. J Virol (1999) 1.75
Vascular bed-specific expression of an endothelial cell gene is programmed by the tissue microenvironment. J Cell Biol (1997) 1.74
Effects of larval mosquitoes (Aedes triseriatus) and stemflow on microbial community dynamics in container habitats. Appl Environ Microbiol (1999) 1.70
Evidence for a prostate cancer-susceptibility locus on chromosome 20. Am J Hum Genet (2000) 1.69
Human cells infected with retrovirus vectors acquire an endogenous murine provirus. J Virol (1990) 1.65
Digitalis (third of four parts). N Engl J Med (1973) 1.63
Calcium and proton activities in rat cardiac mitochondria. Effect of matrix environment on behaviour of fluorescent probes. Biochem J (1989) 1.60
Mechanisms for defects in muscle protein metabolism in rats with chronic uremia. Influence of metabolic acidosis. J Clin Invest (1987) 1.60
In vivo electrophysiologic studies in endothelial nitric oxide synthase (eNOS)-deficient mice. J Cardiovasc Electrophysiol (2001) 1.56
Treatment of life-threatening digitalis intoxication with digoxin-specific Fab antibody fragments: experience in 26 cases. N Engl J Med (1982) 1.56
Abnormal contractile function due to induction of nitric oxide synthesis in rat cardiac myocytes follows exposure to activated macrophage-conditioned medium. J Clin Invest (1993) 1.54
Validating genetic risk associations for ovarian cancer through the international Ovarian Cancer Association Consortium. Br J Cancer (2009) 1.54
Allogeneic bone marrow transplantation for infants with acute leukemia or myelodysplastic syndrome. Bone Marrow Transplant (2001) 1.52
Personality and patient adherence: correlates of the five-factor model in renal dialysis. J Behav Med (1995) 1.51
Regulation of cardiomyocyte mechanotransduction by the cardiac cycle. Circulation (2001) 1.51
Modulation of dihydropyridine-sensitive calcium channels in heart cells by fish oil fatty acids. Proc Natl Acad Sci U S A (1992) 1.50
Localization of HIV-1 co-receptors CCR5 and CXCR4 in the brain of children with AIDS. Am J Pathol (1998) 1.50
Cytokine-inducible nitric oxide synthase (iNOS) expression in cardiac myocytes. Characterization and regulation of iNOS expression and detection of iNOS activity in single cardiac myocytes in vitro. J Biol Chem (1994) 1.49
Characterization of the third member of the MCAT family of cationic amino acid transporters. Identification of a domain that determines the transport properties of the MCAT proteins. J Biol Chem (1993) 1.49
The isolation of digoxin-specific antibody and its use in reversing the effects of digoxin. Proc Natl Acad Sci U S A (1971) 1.46
Positive CSF HSV PCR in patients with GBM: a note of caution. Neurology (2000) 1.43
Digitalis. Circulation (1999) 1.43
Isoforms of nitric oxide synthase. Properties, cellular distribution and expressional control. Biochem Pharmacol (1995) 1.42
Neural basis of endogenous and exogenous spatial orienting. A functional MRI study. J Cogn Neurosci (1999) 1.42
Meningeal gliomatosis presenting as multiple cerebral infarcts: a case report. Neurology (1996) 1.42
The gender gap in reporting household gun ownership. Am J Public Health (1998) 1.42
Digitalis glycosides: mechanisms and manifestations of toxicity. Part I. Prog Cardiovasc Dis (1984) 1.41
Continual electric field stimulation preserves contractile function of adult ventricular myocytes in primary culture. Am J Physiol (1994) 1.41
In vitro binding of purified murine ecotropic retrovirus envelope surface protein to its receptor, MCAT-1. J Virol (1997) 1.41
Immunogenicity and kinetics of distribution and elimination of sheep digoxin-specific IgG and Fab fragments in the rabbit and baboon. Clin Exp Immunol (1979) 1.39
Eosinophilia-myalgia syndrome associated with L-tryptophan ingestion. Analysis of four patients and implications for differential diagnosis and pathogenesis. Arch Intern Med (1990) 1.38
Proximal weakness as the primary manifestation of myotonic dystrophy in older adults. Muscle Nerve (1994) 1.38
Initial experience with a steerable intracardiac echocardiographic catheter. J Invasive Cardiol (1999) 1.38
Comment on the use of the term "Immaculate conceptions" by Meekers, Vol. 42, No. 3-4. Soc Biol (1998) 1.38
Modular organization of the Friend murine leukemia virus envelope protein underlies the mechanism of infection. Proc Natl Acad Sci U S A (2001) 1.37
NRG-1-induced cardiomyocyte hypertrophy. Role of PI-3-kinase, p70(S6K), and MEK-MAPK-RSK. Am J Physiol (1999) 1.37
Properly formed but improperly localized synaptic specializations in the absence of laminin alpha4. Nat Neurosci (2001) 1.37
Plasma concentrations of digoxin after oral administration in the fasting and postprandial ste. Br Med J (1971) 1.36
What's so unhealthy about hostility? Construct validity and psychosocial correlates of the Cook and Medley Ho scale. Health Psychol (1985) 1.35
Treatment of 150 cases of life-threatening digitalis intoxication with digoxin-specific Fab antibody fragments. Final report of a multicenter study. Circulation (1990) 1.35
Dynamic targeting of the agonist-stimulated m2 muscarinic acetylcholine receptor to caveolae in cardiac myocytes. J Biol Chem (1997) 1.33
Genetic analysis of collagen Q: roles in acetylcholinesterase and butyrylcholinesterase assembly and in synaptic structure and function. J Cell Biol (1999) 1.33