Published in J Biol Chem on June 28, 1996
Down-regulation of cAMP-dependent protein kinase by over-activated calpain in Alzheimer disease brain. J Neurochem (2007) 1.10
How does cAMP/protein kinase A signaling lead to tumors in the adrenal cortex and other tissues? Mol Cell Endocrinol (2010) 1.09
Inhibition of Xenopus oocyte meiotic maturation by catalytically inactive protein kinase A. Proc Natl Acad Sci U S A (2002) 1.08
Alternate protein kinase A activity identifies a unique population of stromal cells in adult bone. Proc Natl Acad Sci U S A (2010) 1.04
Attenuation of age-related metabolic dysfunction in mice with a targeted disruption of the Cbeta subunit of protein kinase A. J Gerontol A Biol Sci Med Sci (2009) 0.92
A conserved deamidation site at Asn 2 in the catalytic subunit of mammalian cAMP-dependent protein kinase detected by capillary LC-MS and tandem mass spectrometry. Protein Sci (1998) 0.92
Protein kinase A is a target for aging and the aging heart. Aging (Albany NY) (2010) 0.91
Cross-talk between PKA-Cβ and p65 mediates synergistic induction of PDE4B by roflumilast and NTHi. Proc Natl Acad Sci U S A (2015) 0.87
Elucidating biological risk factors in suicide: role of protein kinase A. Prog Neuropsychopharmacol Biol Psychiatry (2010) 0.85
Protein kinase A translocation and insulin secretion in pancreatic beta-cells: studies with adenylate cyclase toxin from Bordetella pertussis. Biochem J (2002) 0.84
Striatal-enriched protein tyrosine phosphatase regulates the PTPα/Fyn signaling pathway. J Neurochem (2015) 0.82
Protein Kinase A and Anxiety-Related Behaviors: A Mini-Review. Front Endocrinol (Lausanne) (2016) 0.82
The protein kinase A catalytic subunit Cbeta2: molecular characterization and distribution of the splice variant. Biochem J (2000) 0.81
The testis-specific Cα2 subunit of PKA is kinetically indistinguishable from the common Cα1 subunit of PKA. BMC Biochem (2011) 0.80
Hematopoietic neoplasms in Prkar2a-deficient mice. J Exp Clin Cancer Res (2015) 0.77
Targeting protein-protein interactions in complexes organized by A kinase anchoring proteins. Front Pharmacol (2015) 0.77
Haploinsufficiency for either one of the type-II regulatory subunits of protein kinase A improves the bone phenotype of Prkar1a+/- mice. Hum Mol Genet (2015) 0.76
Isolation of cDNA clones coding for the catalytic subunit of mouse cAMP-dependent protein kinase. Proc Natl Acad Sci U S A (1986) 2.20
LKB1, a novel serine/threonine protein kinase and potential tumour suppressor, is phosphorylated by cAMP-dependent protein kinase (PKA) and prenylated in vivo. Biochem J (2000) 1.97
Molecular cloning of human CREB-2: an ATF/CREB transcription factor that can negatively regulate transcription from the cAMP response element. Proc Natl Acad Sci U S A (1992) 1.97
Evidence for a second isoform of the catalytic subunit of cAMP-dependent protein kinase. J Biol Chem (1986) 1.60
The molecular cloning of a type II regulatory subunit of the cAMP-dependent protein kinase from rat skeletal muscle and mouse brain. Proc Natl Acad Sci U S A (1987) 1.42
Transient transfection studies of secretion in bovine chromaffin cells and PC12 cells. Generation of kainate-sensitive chromaffin cells. J Biol Chem (1993) 1.40
Characterization of genomic clones coding for the C alpha and C beta subunits of mouse cAMP-dependent protein kinase. J Biol Chem (1988) 1.34
Regulation of the human enkephalin promoter by two isoforms of the catalytic subunit of cyclic adenosine 3',5'-monophosphate-dependent protein kinase. Mol Endocrinol (1991) 1.29
Analysis of the cAMP-dependent protein kinase system using molecular genetic approaches. Recent Prog Horm Res (1988) 1.20
gRICH68 and gRICH70 are 2',3'-cyclic-nucleotide 3'-phosphodiesterases induced during goldfish optic nerve regeneration. J Biol Chem (1997) 1.13
Cyclic AMP-dependent protein kinase decreases GABAA receptor current in mouse spinal neurons. Neuron (1990) 1.13
Assembly of GABAA receptor subunits: analysis of transient single-cell expression utilizing a fluorescent substrate/marker gene technique. J Neurosci (1993) 1.11
Characterization of PKIgamma, a novel isoform of the protein kinase inhibitor of cAMP-dependent protein kinase. J Biol Chem (1997) 1.05
Phosphorylation-dependent inhibition of protein phosphatase-1 by G-substrate. A Purkinje cell substrate of the cyclic GMP-dependent protein kinase. J Biol Chem (1999) 1.05
Affinity purification of the C alpha and C beta isoforms of the catalytic subunit of cAMP-dependent protein kinase. J Biol Chem (1989) 1.03
Holoenzymes of cAMP-dependent protein kinase containing the neural form of type I regulatory subunit have an increased sensitivity to cyclic nucleotides. J Biol Chem (1990) 1.00
Expression of a cDNA for a neuronal calcium channel alpha 1 subunit enhances secretion from adrenal chromaffin cells. J Biol Chem (1992) 0.99
The type II isoform of cGMP-dependent protein kinase is dimeric and possesses regulatory and catalytic properties distinct from the type I isoforms. J Biol Chem (1995) 0.99
A mutation in the catalytic subunit of protein kinase A prevents myristylation but does not inhibit biological activity. J Biol Chem (1989) 0.98
Induction of alkaline phosphatase in mouse L cells by overexpression of the catalytic subunit of cAMP-dependent protein kinase. J Biol Chem (1990) 0.98
Evidence for two additional isoforms of the endogenous protein kinase inhibitor of cAMP-dependent protein kinase in mouse. J Biol Chem (1993) 0.97
Molecular cloning and expression of mammalian peroxisomal trans-2-enoyl-coenzyme A reductase cDNAs. J Biol Chem (2000) 0.96
Cloning and characterization of zRICH, a 2',3'-cyclic-nucleotide 3'-phosphodiesterase induced during zebrafish optic nerve regeneration. J Neurochem (1999) 0.96
Isolation and characterization of cDNA clones for an inhibitor protein of cAMP-dependent protein kinase. J Biol Chem (1991) 0.94
Inhibition of protein kinase-A by overexpression of the cloned human protein kinase inhibitor. Mol Endocrinol (1991) 0.94
A cGMP-dependent protein kinase is implicated in wild-type motility in C. elegans. J Neurochem (2001) 0.93
The cyclic AMP-dependent protein kinase catalytic subunit selectively enhances calcium currents in rat nodose neurones. J Physiol (1990) 0.93
Molecular cloning and expression of cDNA encoding rat brain cytosolic acyl-coenzyme A thioester hydrolase. J Biol Chem (1996) 0.89
Dynorphin A and cAMP-dependent protein kinase independently regulate neuronal calcium currents. Proc Natl Acad Sci U S A (1990) 0.89
Cyclic AMP- and cyclic GMP-dependent protein kinases differ in their regulation of cyclic AMP response element-dependent gene transcription. J Biol Chem (1999) 0.88
Evidence for association of the cloned liver growth hormone receptor with a tyrosine kinase. J Biol Chem (1992) 0.86
The amino-terminal cyclic nucleotide binding site of the type II cGMP-dependent protein kinase is essential for full cyclic nucleotide-dependent activation. J Biol Chem (2000) 0.86
Comparison of fura-2 imaging and electrophysiological analysis of murine calcium channel alpha 1 subunits coexpressed with novel beta 2 subunit isoforms. Mol Pharmacol (1995) 0.85
Cloning of CDP-diacylglycerol synthase from a human neuronal cell line. J Neurochem (1996) 0.85
Enhancement of recombinant gamma-aminobutyric acid type A receptor currents by chronic activation of cAMP-dependent protein kinase. Mol Pharmacol (1993) 0.85
Deficient gene expression in protein kinase inhibitor alpha Null mutant mice. Mol Cell Biol (2000) 0.84
Isoform-specific differences in the potencies of murine protein kinase inhibitors are due to nonconserved amino-terminal residues. J Biol Chem (1995) 0.84
Localization of cGMP-dependent protein kinase isoforms in mouse eye. Invest Ophthalmol Vis Sci (2000) 0.81
Evidence for the importance of hydrophobic residues in the interactions between the cAMP-dependent protein kinase catalytic subunit and the protein kinase inhibitors. J Biol Chem (1994) 0.80
Sertoli cells are the primary site of prodynorphin gene expression in rat testis: regulation of mRNA and secreted peptide levels by cyclic adenosine 3' ,5'-monophosphate analogs in cultured cells. Mol Endocrinol (1990) 0.80
Isolation of cDNA clones encoding RICH: a protein induced during goldfish optic nerve regeneration with homology to mammalian 2',3'-cyclic-nucleotide 3'-phosphodiesterases. Proc Natl Acad Sci U S A (1995) 0.80
Differential expression of mRNAs for protein kinase inhibitor isoforms in mouse brain. Proc Natl Acad Sci U S A (1995) 0.80
Glutamic acid 203 of the cAMP-dependent protein kinase catalytic subunit participates in the inhibition by two isoforms of the protein kinase inhibitor. J Biol Chem (1994) 0.79
Application of molecular genetic techniques to the cAMP-dependent protein kinase system. Methods Enzymol (1988) 0.79
Determination of protein expression and plasmid copy number from cloned genes in Escherichia coli by flow injection analysis using an enzyme indicator vector. Biotechnol Bioeng (1989) 0.78
The reduction of neuronal calcium currents by ATP-gamma-S is mediated by a G protein and occurs independently of cyclic AMP-dependent protein kinase. Brain Res (1990) 0.78
Investigation by transient transfection of the effects on regulated exocytosis of Rab3a. Methods Enzymol (1995) 0.75
Genetic alteration of cyclic adenosine 3',5'-monophosphate-dependent protein kinase subunit expression affects calcium currents and beta-endorphin release in AtT-20 clonal pituitary cells. Mol Endocrinol (1994) 0.75
The mouse Prkacn2 gene encoding protein kinase A inhibitor 2 is located on proximal chromosome 10. Mamm Genome (1996) 0.75
Nerve growth factor inhibits PC12 cell PDE 2 phosphodiesterase activity and increases PDE 2 binding to phosphoproteins. J Neurochem (2001) 0.75
Implications of a simple mathematical model to cancer cell population dynamics. Cell Prolif (2006) 0.75