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Genetic linkage map of human chromosome 7 with 63 DNA markers. Proc Natl Acad Sci U S A (1987) 2.91
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Mapping haemoglobin genes. Br Med J (1979) 0.84
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Exclusion of human chromosome 13q34 as the site of the cystic fibrosis mutation. Am J Hum Genet (1986) 0.75
Gene therapy. Gut (1992) 0.75
Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens-new tools for genetic analysis. Cell (1978) 14.82
Localization of the gene for familial adenomatous polyposis on chromosome 5. Nature (1987) 10.21
The number of balanced polymorphisms that can be maintained in a natural population. Genetics (1967) 8.80
Linkage and selection: theoretical analysis of the deterministic two locus random mating model. Genetics (1967) 7.12
Monoclonal antibodies for analysis of the HLA system. Immunol Rev (1979) 6.63
HL-A, immune-response genes, and disease. Lancet (1974) 5.67
p53 mutations in colorectal cancer. Proc Natl Acad Sci U S A (1990) 5.43
Use of a monoclonal antibody (W6/32) in structural studies of HLA-A,B,C, antigens. J Immunol (1979) 5.06
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A migration matrix model for the study of random genetic drift. Genetics (1968) 4.59
Chromosome 5 allele loss in human colorectal carcinomas. Nature (1987) 4.46
HL-A antigens and disease. Statistical and genetical considerations. Tissue Antigens (1974) 4.41
Monoclonal antibody to cytokeratin for use in routine histopathology. J Clin Pathol (1984) 4.36
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Evolutionary significance of the HL-A system. Nature (1972) 4.06
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PIC 1, a novel ubiquitin-like protein which interacts with the PML component of a multiprotein complex that is disrupted in acute promyelocytic leukaemia. Oncogene (1996) 3.73
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Molecular analysis of APC mutations in familial adenomatous polyposis and sporadic colon carcinomas. Lancet (1992) 3.44
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The Eurasian heartland: a continental perspective on Y-chromosome diversity. Proc Natl Acad Sci U S A (2001) 3.38
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Characterization of a monoclonal anti-beta 2-microglobulin antibody and its use in the genetic and biochemical analysis of major histocompatibility antigens. Eur J Immunol (1979) 3.27
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Recombination and integration in Bacillus subtilis transformation: involvement of DNA synthesis. J Mol Biol (1965) 3.21
Haplotype and phenotype analysis of six recurrent BRCA1 mutations in 61 families: results of an international study. Am J Hum Genet (1996) 2.97
Monoclonal antibody to a human histocompatibility alloantigen, HLA-A2. Nature (1978) 2.93
The solution structure of the RING finger domain from the acute promyelocytic leukaemia proto-oncoprotein PML. EMBO J (1995) 2.93
Evolution and function of the HLA system. Br Med Bull (1978) 2.91
Identification and characterization of the human type II collagen gene (COL2A1). Proc Natl Acad Sci U S A (1985) 2.80
The mutation rate and cancer. Proc Natl Acad Sci U S A (1996) 2.73
Histocompatibility (HL-A) antigens associated with systemic lupus erythematosus. A possible genetic predisposition to disease. N Engl J Med (1971) 2.69
CpG island clones from a deletion encompassing the gene for adenomatous polyposis coli. Proc Natl Acad Sci U S A (1989) 2.66
Protein clinical manifestations of primary tumors of the heart. Am J Med (1972) 2.61
Report of the committee on the genetic constitution of chromosome 17. Cytogenet Cell Genet (1989) 2.59
Human genetics: the molecular challenge. Cold Spring Harb Symp Quant Biol (1986) 2.54
cDNA clones coding for the heavy chain of human HLA-DR antigen. Proc Natl Acad Sci U S A (1982) 2.51
Targeting of iodine-123-labelled tumour-associated monoclonal antibodies to ovarian, breast, and gastrointestinal tumours. Lancet (1982) 2.51
Mutations affecting the dissimilation of mannitol by Escherichia coli K-12. J Bacteriol (1972) 2.46
SUMO-1 modification of the acute promyelocytic leukaemia protein PML: implications for nuclear localisation. J Cell Sci (1999) 2.46
The genetic control of HLA-A and B antigens in somatic cell hybrids: requirement for beta2 microglobulin. Tissue Antigens (1978) 2.40
A highly polymorphic region 3' to the human type II collagen gene. Nucleic Acids Res (1985) 2.37
THRA1 and D17S183 flank an interval of < 4 cM for the breast-ovarian cancer gene (BRCA1) on chromosome 17q21. Am J Hum Genet (1993) 2.37
Integration of deoxyribonuclease-treated DNA in bacillus subtilis transformation. J Gen Physiol (1966) 2.32
The beta2-microglobulin gene is on chromosome 15 and not in the HL-A region. Nature (1975) 2.29
The APC variants I1307K and E1317Q are associated with colorectal tumors, but not always with a family history. Proc Natl Acad Sci U S A (1998) 2.27
Polyclonal origin of colonic adenomas in an XO/XY patient with FAP. Science (1996) 2.22
Sequence of an HLA-DR alpha-chain cDNA clone and intron-exon organization of the corresponding gene. Nature (1982) 2.18
Methylation of the BRCA1 promoter region in sporadic breast and ovarian cancer: correlation with disease characteristics. Oncogene (1999) 2.09
Intrathecal fentanyl with small-dose dilute bupivacaine: better anesthesia without prolonging recovery. Anesth Analg (1997) 2.09
Cellular distrubtion, purification, and molecular nature of human Ia antigens. Scand J Immunol (1977) 2.04
Chromosomal localisation of the human homologues to the oncogenes erbA and B. EMBO J (1984) 2.02
A monoclonal antibody that detects HLA-D region antigen in routinely fixed, wax embedded sections of normal and neoplastic lymphoid tissues. J Clin Pathol (1985) 2.00
Assignment of the structural gene for the third component of human complement to chromosome 19. Proc Natl Acad Sci U S A (1982) 2.00
Rapid isolation of human chromosome-specific DNA probes from a somatic cell hybrid. Genomics (1990) 1.99
Genetic factors in Hodgkin's disease: association with a disease-susceptibility locus (DSA) in the HL-A region. Natl Cancer Inst Monogr (1973) 1.98
Nomenclature for factors of the HLA system, 1990. Tissue Antigens (1991) 1.98
Chromosomal localization of human cellular homologues of two viral oncogenes. Nature (1982) 1.96
Clinical and molecular features of the hereditary mixed polyposis syndrome. Gastroenterology (1997) 1.96
Isolation and characterization of a human collagen alpha 1(I)-like gene from a cosmid library. Nucleic Acids Res (1982) 1.94
Six HLA-D region alpha-chain genes on human chromosome 6: polymorphisms and associations of DC alpha-related sequences with DR types. Proc Natl Acad Sci U S A (1984) 1.90
Nomenclature for factors of the HLA system, 2002. Tissue Antigens (2002) 1.89
Human T cell leukemia viruses use a receptor determined by human chromosome 17. Science (1988) 1.87
The gene, MIC4, which controls expression of the antigen defined by monoclonal antibody F10.44.2, is on human chromosome 11. Eur J Immunol (1982) 1.86
Immunoglobulin heavy chain genes in humans are located on chromosome. Ann Hum Genet (1981) 1.85
Spectral karyotyping suggests additional subsets of colorectal cancers characterized by pattern of chromosome rearrangement. Proc Natl Acad Sci U S A (2001) 1.85
Production and characterization of monoclonal antibodies recognizing the alpha-chain subunits of human ia alloantigens. Immunology (1983) 1.85
Insulin-like growth factor 1 regulates the location, stability, and transcriptional activity of beta-catenin. Proc Natl Acad Sci U S A (2000) 1.83
Germline mutations in BMPR1A/ALK3 cause a subset of cases of juvenile polyposis syndrome and of Cowden and Bannayan-Riley-Ruvalcaba syndromes. Am J Hum Genet (2001) 1.81
New genetic model for allelism at histocompatibility and other complex loci: polymorphism for control of gene expression. Transplant Proc (1973) 1.80
Hypertrophic cardiomyopathy associated with dexamethasone therapy for bronchopulmonary dysplasia. J Pediatr (1992) 1.79
Failure of programmed cell death and differentiation as causes of tumors: some simple mathematical models. Proc Natl Acad Sci U S A (1995) 1.78
Use of two epithelium-specific monoclonal antibodies for diagnosis of malignancy in serous effusions. Lancet (1982) 1.76
APC in the regulation of intestinal crypt fission. J Pathol (1998) 1.73
Intestinal trefoil factor controls the expression of the adenomatous polyposis coli-catenin and the E-cadherin-catenin complexes in human colon carcinoma cells. Proc Natl Acad Sci U S A (1998) 1.70
Human elastin gene: new evidence for localization to the long arm of chromosome 7. Am J Hum Genet (1991) 1.69
Complex regulation of the BRCA1 gene. J Biol Chem (1997) 1.68
Genetic testing is important in families with a history suggestive of hereditary non-polyposis colorectal cancer even if the Amsterdam criteria are not fulfilled. Br J Surg (1997) 1.66
SMAD4 mutations in colorectal cancer probably occur before chromosomal instability, but after divergence of the microsatellite instability pathway. Proc Natl Acad Sci U S A (2001) 1.65
The chromosomal location of T-cell receptor genes and a T cell rearranging gene: possible correlation with specific translocations in human T cell leukaemia. EMBO J (1985) 1.64
Molecular structure of human histocompatibility antigens: the HLA-C series. Eur J Immunol (1977) 1.61
Nucleotide sequence of cDNA encoding human alpha 2-macroglobulin and assignment of the chromosomal locus. Proc Natl Acad Sci U S A (1985) 1.59
Two-dimensional gel analysis of the polypeptides precipitated by a polymorphic HLA-DR1,2,w6 monoclonal antibody: evidence for a third locus. Eur J Immunol (1982) 1.59
Nomenclature for factors of the HLA system, 1991. WHO Nomenclature Committee for factors of the HLA system. Tissue Antigens (1992) 1.58
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Expression of HLA antigens, beta 2-microglobulin and enzymes by human amniotic epithelial cells. Nature (1982) 1.57
Expression of HLA system antigens on placenta. Transplantation (1976) 1.56
Molecular genetics. Colorectal cancer genes. Nature (1990) 1.56
Localization of the oncogene c-erbA1 immediately proximal to the acute promyelocytic leukaemia breakpoint on chromosome 17. Ann Hum Genet (1985) 1.55
Intron splice acceptor site sequence variation in the hereditary non-polyposis colorectal cancer gene hMSH2. Eur J Cancer (1994) 1.54