Published in Science on July 22, 1977
Mucosal immunology. Immunology (1980) 3.84
Mucosal barrier mechanisms. Interplay between secretory IgA (SIgA), IgG and mucins on the surface properties and association of salmonellae with intestine and granulocytes. Immunology (1982) 1.58
Immune exclusion and mucus trapping during the rapid expulsion of Nippostrongylus brasiliensis from primed rats. Immunology (1981) 1.56
Functions of p21 and p27 in the regenerating epithelial linings of the mouse small and large intestine. Cancer Biol Ther (2008) 1.41
Immunologic and neuropharmacologic stimulation of mucous glycoprotein release from human airways in vitro. J Clin Invest (1980) 1.39
Anti-lactoferrin antibodies and other types of ANCA in ulcerative colitis, primary sclerosing cholangitis, and Crohn's disease. Gut (1993) 1.39
Complexity of rice-water stool from patients with Vibrio cholerae plays a role in the transmission of infectious diarrhea. Proc Natl Acad Sci U S A (2007) 1.31
Activation of lamina propria T cells induces crypt epithelial proliferation and goblet cell depletion in cultured human fetal colon. Gut (1992) 1.17
Anaphylactic release of intestinal goblet cell mucus. Immunology (1980) 1.12
Immune-mediated alteration of the terminal sugars of goblet cell mucins in the small intestine of Nippostrongylus brasiliensis-infected rats. Immunology (1993) 1.02
Successful experimental challenge of dogs with canine parvovirus-2. Can J Comp Med (1982) 0.97
Intestinal uptake of macromolecules. Differences in distribution and degradation of protein antigen in control and immunised rats. Gut (1981) 0.87
Antigen handling by the gut. Arch Dis Child (1978) 0.83
Murine interleukin-2 generates glycogen-rich and mucus-secreting NK cells. Immunology (1983) 0.77
The sequence of the human genome. Science (2001) 101.55
Role of AMP-activated protein kinase in mechanism of metformin action. J Clin Invest (2001) 23.21
Lysophosphatidic acid as a potential biomarker for ovarian and other gynecologic cancers. JAMA (1998) 5.09
A simple colorimetric method for determination of protein. Anal Biochem (1969) 4.87
Reducing obesity and related chronic disease risk in children and youth: a synthesis of evidence with 'best practice' recommendations. Obes Rev (2006) 4.74
Cell cycle dynamics of an M-phase-specific cytoplasmic factor in Xenopus laevis oocytes and eggs. J Cell Biol (1984) 4.20
Clinical relevance of the primary findings of the MTA: success rates based on severity of ADHD and ODD symptoms at the end of treatment. J Am Acad Child Adolesc Psychiatry (2001) 3.87
Actin-dependent propulsion of endosomes and lysosomes by recruitment of N-WASP. J Cell Biol (2000) 3.71
Genome of Geobacter sulfurreducens: metal reduction in subsurface environments. Science (2003) 3.68
Uptake and transport of macromolecules by the intestine. Possible role in clinical disorders. Gastroenterology (1974) 3.33
Antibodies involved in antigen-induced release of slow reacting substance of anaphylaxis (SRS-A) in the guinea pig and rat. J Exp Med (1967) 3.08
Intestinal uptake of macromolecules: effect of oral immunization. Science (1972) 2.80
Cell cycle tyrosine phosphorylation of p34cdc2 and a microtubule-associated protein kinase homolog in Xenopus oocytes and eggs. Mol Cell Biol (1991) 2.69
Oxidative damage and protection of the RPE. Prog Retin Eye Res (2000) 2.65
Genetic relationship of populations in China. Proc Natl Acad Sci U S A (1998) 2.65
Immunoglobulins on the surface of neoplastic lymphocytes. N Engl J Med (1972) 2.63
Inflammation in the developing human intestine: A possible pathophysiologic contribution to necrotizing enterocolitis. Proc Natl Acad Sci U S A (2000) 2.61
A preliminary study of aerosolized recombinant human deoxyribonuclease I in the treatment of cystic fibrosis. N Engl J Med (1992) 2.57
Partial purification and characterization of the maturation-promoting factor from eggs of Xenopus laevis. Dev Biol (1980) 2.53
Lithium phthalocyanine: a probe for electron paramagnetic resonance oximetry in viable biological systems. Proc Natl Acad Sci U S A (1993) 2.50
Small intestinal permeability to macromolecules. Transmission of horseradish peroxidase into mesenteric lymph and portal blood. Lab Invest (1971) 2.46
Establishment of the dorso-ventral axis in Xenopus embryos is presaged by early asymmetries in beta-catenin that are modulated by the Wnt signaling pathway. J Cell Biol (1997) 2.42
The anaphylactic antibodies of mammals including man. Prog Allergy (1967) 2.38
Hypothesis: inappropriate colonization of the premature intestine can cause neonatal necrotizing enterocolitis. FASEB J (2001) 2.34
Skeletal benefits of alendronate: 7-year treatment of postmenopausal osteoporotic women. Phase III Osteoporosis Treatment Study Group. J Clin Endocrinol Metab (2000) 2.34
An approximate generalized linear model with random effects for informative missing data. Biometrics (1995) 2.34
Changes in protein phosphorylation accompanying maturation of Xenopus laevis oocytes. Dev Biol (1977) 2.31
Spontaneous rupture of the esophagus: a 30-year experience. Ann Thorac Surg (1989) 2.22
Polyadenylation of c-mos mRNA as a control point in Xenopus meiotic maturation. Nature (1995) 2.21
Small intestinal absorption of horseradish peroxidase. A cytochemical study. Lab Invest (1971) 2.20
Defining the smallest analyte concentration an immunoassay can measure. Clin Chem (1996) 2.18
Increased susceptibility to infection in a patient with type II essential hypercatabolism of C3. N Engl J Med (1973) 2.17
Azithromycin for treatment of Mycobacterium avium-intracellulare complex infection in patients with AIDS. Lancet (1991) 2.15
The 1993 Walter Hubert Lecture: the role of the p53 tumour-suppressor gene in tumorigenesis. Br J Cancer (1994) 2.14
Akt-mediated phosphorylation of the G protein-coupled receptor EDG-1 is required for endothelial cell chemotaxis. Mol Cell (2001) 2.11
Targeted disruption of the tumor necrosis factor-alpha gene: metabolic consequences in obese and nonobese mice. Diabetes (1997) 2.10
Three-year maintenance of improved diet and physical activity: the CATCH cohort. Child and Adolescent Trial for Cardiovascular Health. Arch Pediatr Adolesc Med (1999) 2.07
Repression of transcription of the p27(Kip1) cyclin-dependent kinase inhibitor gene by c-Myc. Oncogene (2001) 2.05
Secreted noggin protein mimics the Spemann organizer in dorsalizing Xenopus mesoderm. Nature (1993) 2.02
Immune factors in breast milk and the development of atopic disease. J Pediatr Gastroenterol Nutr (2012) 2.02
Structure of a nicked DNA-protein complex isolated from simian virus 40: covalent attachment of the protein to DNA and nick specificity. Proc Natl Acad Sci U S A (1976) 1.95
Effect of L-000845704, an alphaVbeta3 integrin antagonist, on markers of bone turnover and bone mineral density in postmenopausal osteoporotic women. J Clin Endocrinol Metab (2005) 1.94
Treatment of experimental disseminated Mycobacterium avium complex infection in mice with recombinant IL-2 and tumor necrosis factor. J Immunol (1989) 1.92
Use of gene 32 protein staining of single-strand polynucleotides for gene mapping by electron microscopy: application to the phi80d3ilvsu+7 system. Proc Natl Acad Sci U S A (1975) 1.92
microRNA-22, downregulated in hepatocellular carcinoma and correlated with prognosis, suppresses cell proliferation and tumourigenicity. Br J Cancer (2010) 1.90
Immunologic relationship between blood group substances and a fucose-containing glycolipid of human adenocarcinoma. J Immunol (1967) 1.88
Hapten-specific IgE antibody responses in mice. I. Secondary IgE responses in irradiated recipients of syngeneic primed spleen cells. J Exp Med (1973) 1.87
Intestinal antibodies. N Engl J Med (1977) 1.82
TGF beta 1 inhibits NF-kappa B/Rel activity inducing apoptosis of B cells: transcriptional activation of I kappa B alpha. Immunity (1996) 1.81
Evidence for an innate immune response in the immature human intestine: toll-like receptors on fetal enterocytes. Pediatr Res (2001) 1.80
An intervening sequence in an unusual histone H1 gene of Tetrahymena thermophila. Proc Natl Acad Sci U S A (1986) 1.79
Mineral trioxide aggregate: a new material for endodontics. J Am Dent Assoc (1999) 1.79
Native low-density lipoprotein increases endothelial cell nitric oxide synthase generation of superoxide anion. Circ Res (1995) 1.76
MTO1 codes for a mitochondrial protein required for respiration in paromomycin-resistant mutants of Saccharomyces cerevisiae. J Biol Chem (1998) 1.72
Heterogeneity in biologic functions of antibodies: implications for immunologic tumor enhancement. Fed Proc (1966) 1.72
Physical mapping of the transfer RNA genes on lambda-h80dglytsu+36. J Mol Biol (1973) 1.72
Inhibition of a reductive function of the plasma membrane by bacitracin and antibodies against protein disulfide-isomerase. Proc Natl Acad Sci U S A (1993) 1.71
The role of cyclin synthesis, modification and destruction in the control of cell division. J Cell Sci Suppl (1989) 1.69
Expression of the mitochondrial genome in HeLa cells. XIV. The relative positions of the 4 S RNA genes and of the ribosomal RNA genes in mitochondrial DNA. J Mol Biol (1972) 1.68
High incidence of single nucleotide substitutions in the mitochondrial genome is associated with poor semen parameters in men. Int J Androl (2001) 1.68
Antinuclear factors in synovia. Possible participants in the rheumatoid inclusion body. JAMA (1966) 1.67
Macromolecular absorption. Mechanism of horseradish peroxidase uptake and transport in adult and neonatal rat intestine. J Cell Biol (1972) 1.66
Molecular and functional analysis of a lymphocyte chemoattractant factor: association of biologic function with CD4 expression. Proc Natl Acad Sci U S A (1994) 1.65
IgE and IgGa antibody-mediated release of histamine from rat peritoneal cells. I. Optimum conditions for in vitro preparation of target cells with antibody and and challenge with antigen. J Exp Med (1971) 1.64
Impairment and deportment responses to different methylphenidate doses in children with ADHD: the MTA titration trial. J Am Acad Child Adolesc Psychiatry (2001) 1.63
Expression of yeast apurinic/apyrimidinic endonuclease (APN1) protects lung epithelial cells from bleomycin toxicity. Am J Respir Cell Mol Biol (2001) 1.63
Cell-surface immunoglobulins in chronic lymphocytic leukemia and allied disorders. Am J Med (1973) 1.61
Homocytotropic antibody response in the rat infected with the nematode, Nippostrongylus brasiliensis. II. Characteristics of the immune response. J Immunol (1968) 1.59
The increased bone mass in deltaFosB transgenic mice is independent of circulating leptin levels. Endocrinology (2002) 1.59
Clinical features and history of the destructive lung disease associated with alpha-1-antitrypsin deficiency of adults with pulmonary symptoms. Am Rev Respir Dis (1988) 1.58
Nutrition education at the point of purchase: the foods for health project evaluated. Prev Med (1986) 1.56
Mitochondrial and cytoplasmic fumarases in Saccharomyces cerevisiae are encoded by a single nuclear gene FUM1. J Biol Chem (1987) 1.56
The zymogen of tadpole collagenase. Biochemistry (1971) 1.56
Regulation of NKB pathways and their roles in the control of Kiss1 neurons in the arcuate nucleus of the male mouse. Endocrinology (2011) 1.55
Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB(1) and CB(2) receptor binding. Drug Alcohol Depend (2000) 1.55
Sequence arrangement of tRNA genes on a fragment of Drosophila melanogaster DNA cloned in E. coli. Cell (1977) 1.54
Inhibition of human skin collagenase by human serum. J Lab Clin Med (1970) 1.53
Protein uptake by the intestine: evidence for absorption of intact macromolecules. Gastroenterology (1974) 1.53
Intestinal uptake of macromolecules. II. Effect of parenteral immunization. J Immunol (1973) 1.53
Amikacin, ciprofloxacin, and imipenem treatment for disseminated Mycobacterium avium complex infection of beige mice. Antimicrob Agents Chemother (1989) 1.52
A randomized trial of a self-help smoking cessation intervention in a nonvolunteer female population: testing the limits of the public health model. Health Psychol (1992) 1.51
Efficacy and tolerability of the dipeptidyl peptidase-4 inhibitor sitagliptin as monotherapy over 12 weeks in patients with type 2 diabetes. Int J Clin Pract (2006) 1.50
Biologic properties of rat antibodies. I. Antigen-binding by four classes of anti-DNP antibodies. J Immunol (1968) 1.50
Intracellular killing of Mycobacterium avium complex by rifapentine and liposome-encapsulated amikacin. J Infect Dis (1987) 1.49
Yersinia enterocolitica infection: report of two cases. Can J Public Health (1973) 1.49
Biologic properties of rat antibodies. 3. Histamine release mediated by two classes of antibodies. J Immunol (1969) 1.49
Intestinal uptake of macromolecules. III. Studies on the mechanism by which immunization interferes with antigen uptake. J Immunol (1975) 1.49
Human fetal enterocytes in vitro: modulation of the phenotype by extracellular matrix. Proc Natl Acad Sci U S A (1996) 1.49
Anaphylaxis during induction of general anesthesia: subsequent evaluation and management. J Allergy Clin Immunol (1990) 1.46
Antigenicity of infant formulas: role of immature intestine on protein permeability. J Pediatr (1978) 1.45
In vitro and in vivo activity of azithromycin (CP 62,993) against the Mycobacterium avium complex. J Infect Dis (1989) 1.44
Design of the Lung Health Study: a randomized clinical trial of early intervention for chronic obstructive pulmonary disease. Control Clin Trials (1993) 1.43
Immunoconglutinin in various rheumatic diseases and certain diseases suspected of an autoimmune pathogenesis. Arthritis Rheum (1967) 1.43
The remineralizing effect of an essential oil fluoride mouthrinse in an intraoral caries test. J Am Dent Assoc (2004) 1.42
Video-assisted thoracic surgery: primary therapy for spontaneous pneumothorax? Ann Thorac Surg (1995) 1.42