Published in Am J Pathol on August 01, 1977
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Aspirin selectively inhibits prostaglandin production in human platelets. Nat New Biol (1971) 7.75
Isolation and structure of two prostaglandin endoperoxides that cause platelet aggregation. Proc Natl Acad Sci U S A (1974) 7.00
Quantitative nitroblue tetrazolium test in chronic granulomatous disease. N Engl J Med (1968) 6.91
The pathogenesis of atherosclerosis (second of two parts). N Engl J Med (1976) 5.48
Fine structural alterations induced in platelets by adenosine diphosphate. Blood (1968) 4.95
Isolation and properties of intermediates in prostaglandin biosynthesis. Biochim Biophys Acta (1973) 4.45
The effect of salicylates on the hemostatic properties of platelets in man. J Clin Invest (1968) 3.66
Platelet interaction with bacteria. I. Reaction phases and effects of inhibitors. Am J Pathol (1971) 3.04
Arachidonate lipoxygenase in blood platelets. Biochim Biophys Acta (1975) 2.84
Metabolism of [14C]arachidonic acid by human platelets. Biochim Biophys Acta (1976) 2.61
Thromboxanes: selective biosynthesis and distinct biological properties. Science (1976) 2.46
The role of superoxide anion and hydrogen peroxide in phagocytosis-associated oxidative metabolic reactions. J Clin Invest (1975) 2.40
Interaction of membrane systems in blood platelets. Am J Pathol (1972) 2.32
An endoperoxide aggregator (Lass), formed in platelets in response to thrombotic stimuli: purification, identification and unique biological significance. Prostaglandins (1974) 2.02
Some effects of fibrinogen degradation products (FDP) on blood platelets. Thromb Diath Haemorrh (1966) 1.82
Physiological role of an endoperoxide in human platelets: hemostatic defect due to platelet cyclo-oxygenase deficiency. Proc Natl Acad Sci U S A (1975) 1.74
Arachidonic acid-induced human platelet aggregation and prostaglandin formation. Prostaglandins (1973) 1.69
Oxygen: boon and bane. Am Sci (1975) 1.63
Formation and release of prostaglandins by platelets in response to thrombin. Br J Pharmacol (1970) 1.59
Isolation of a chemical trigger for thrombosis. Prostaglandins (1974) 1.57
Superoxide production and reducing activity in human platelets. J Clin Invest (1977) 1.43
Localization of platelet prostaglandin production in the platelet dense tubular system. Am J Pathol (1976) 1.40
Investigation of the release reaction in platelets exposed to phorbol myristate acetate. Am J Pathol (1974) 1.39
Aspirin-induced depression of renal function. N Engl J Med (1977) 1.33
Role of superoxide radicals in the lipid peroxidation of intracellular membranes. FEBS Lett (1975) 1.29
Effects of the lonophore A23187 on the blood platelets II. Influence on ultrastructure. Am J Pathol (1974) 1.27
Letter: Peroxy radical cyclization as a model for prostaglandin biosynthesis. J Org Chem (1975) 1.22
A new potential mediator of arterial thrombosis whose biosynthesis is inhibited by aspirin. Prostaglandins (1973) 1.17
The role of blood and platelets in atherosclerosis and the complications of atherosclerosis. Thromb Diath Haemorrh (1975) 1.09
Labile aggregation stimulating substance (LASS): the factor from storage pool deficient platelets correcting defective aggregation and release of aspirin treated normal platelets. Br J Haematol (1975) 1.05
Oxygen and cyclic nucleotides in human umbilical artery. Proc Natl Acad Sci U S A (1975) 1.02
The basis of free radical pathology. Fed Proc (1973) 1.02
Histochemical localisation of prostaglandin synthetase. Histochemie (1971) 1.01
The influence of aspirin and indomethacin on the platelet contractile wave. Am J Pathol (1976) 1.01
Editorial: NBT reduction by human phagocytes. N Engl J Med (1974) 1.00
Role of hydroxyl radical scavengers dimethyl sulfoxide, alcohols and methional in the inhibition of prostaglandin biosynthesis. Prostaglandins (1976) 0.98
Vitamin E. An inhibitor of the platelet release reaction. J Clin Invest (1976) 0.98
The platelet: membrane and surface reactions. Annu Rev Physiol (1976) 0.98
Free radicals and the action of inhibitors of radical processes under pathological states and ageing in living organisms and in man. Q Rev Biophys (1976) 0.97
Light emission during the action of prostaglandin synthetase. Biochem Biophys Res Commun (1974) 0.97
Control of free radicals in biologic systems. Fed Proc (1973) 0.96
Co-oxygenation of organic substrates by the prostaglandin synthetase of sheep vesicular gland. J Biol Chem (1975) 0.92
The influence of prostaglandin endoperoxides on platelet ultrastructure. Am J Pathol (1975) 0.92
A suggested role for hydrogen peroxide in the biosynthesis of prostaglandins. Prostaglandins (1974) 0.91
Blockade by metal complexing agents and by catalase of the effects of arachidonic acid on platelets: relevance to the study of anti-inflammatory mechanisms. Eur J Pharmacol (1975) 0.89
Control by TSH of a phospholipase A 2 activity, a limiting factor in the biosynthesis of prostaglandins in the thyroid. FEBS Lett (1973) 0.85
Influence of vitamin E on platelet aggregation and thrombocythemia in the rat. Proc Soc Exp Biol Med (1975) 0.81
Labile aggregation stimulating substance, free fatty acids, and platelet aggregation. J Lab Clin Med (1976) 0.80
Smoking and platelet labile aggregation stimulating substance (LASS) synthesizing activity. Thromb Res (1976) 0.79
Production of the superoxide radical by horseradish peroxidase. Biochem Soc Trans (1976) 0.77
Alpha-tocopherol: its inhibition on human platelet aggregation. Experientia (1976) 0.76
The embryonic cell lineage of the nematode Caenorhabditis elegans. Dev Biol (1983) 21.29
In vitro bactericidal capacity of human polymorphonuclear leukocytes: diminished activity in chronic granulomatous disease of childhood. J Clin Invest (1967) 10.26
The neural circuit for touch sensitivity in Caenorhabditis elegans. J Neurosci (1985) 7.13
Electron microscopical reconstruction of the anterior sensory anatomy of the nematode Caenorhabditis elegans.?2UU. J Comp Neurol (1975) 6.58
Complement (C5-a)-induced granulocyte aggregation in vitro. A possible mechanism of complement-mediated leukostasis and leukopenia. J Clin Invest (1977) 5.16
Fine structural alterations induced in platelets by adenosine diphosphate. Blood (1968) 4.95
Cortical flow in animal cells. Science (1988) 4.66
An evaluation of confocal versus conventional imaging of biological structures by fluorescence light microscopy. J Cell Biol (1987) 4.59
Multiphoton excitation provides optical sections from deeper within scattering specimens than confocal imaging. Biophys J (1998) 4.44
On the control of germ cell development in Caenorhabditis elegans. Dev Biol (1981) 4.28
Determination of cell division axes in the early embryogenesis of Caenorhabditis elegans. J Cell Biol (1987) 4.20
The structure of the ventral nerve cord of Caenorhabditis elegans. Philos Trans R Soc Lond B Biol Sci (1976) 3.94
Regulation and cell autonomy during postembryonic development of Caenorhabditis elegans. Dev Biol (1980) 3.88
Familial dyserythropoietic anaemia and thrombocytopenia due to an inherited mutation in GATA1. Nat Genet (2000) 3.50
Long-term two-photon fluorescence imaging of mammalian embryos without compromising viability. Nat Biotechnol (1999) 3.44
Platelet interaction with bacteria. I. Reaction phases and effects of inhibitors. Am J Pathol (1971) 3.04
The C. elegans zyg-1 gene encodes a regulator of centrosome duplication with distinct maternal and paternal roles in the embryo. Cell (2001) 2.92
Completion of cytokinesis in C. elegans requires a brefeldin A-sensitive membrane accumulation at the cleavage furrow apex. Curr Biol (2001) 2.64
On the mechanisms of cytokinesis in animal cells. J Theor Biol (1983) 2.63
Cortical and cytoplasmic flow polarity in early embryonic cells of Caenorhabditis elegans. J Cell Biol (1993) 2.54
The dynactin complex is required for cleavage plane specification in early Caenorhabditis elegans embryos. Curr Biol (1998) 2.53
Abnormal adherence of sickle erythrocytes to cultured vascular endothelium: possible mechanism for microvascular occlusion in sickle cell disease. J Clin Invest (1980) 2.34
Interaction of membrane systems in blood platelets. Am J Pathol (1972) 2.32
Specific degranulation of human polymorphonuclear leukocytes. Nature (1974) 2.30
Selective labilization of specific granules in polymorphonuclear leukocytes by phorbol myristate acetate. Am J Pathol (1974) 2.27
An ultrastructural basis for the shape changes induced in platelets by chilling. Blood (1967) 2.20
The ultrastructural localization and release of platelet lipids. Blood (1966) 2.10
Dynamics and ultrastructure of developmental cell fusions in the Caenorhabditis elegans hypodermis. Curr Biol (1998) 2.04
Biochemical studies of two patients with the gray platelet syndrome. Selective deficiency of platelet alpha granules. J Clin Invest (1980) 2.01
Corticosteroids inhibit complement-induced granulocyte aggregation. A possible mechanism for their efficacy in shock states. J Clin Invest (1979) 2.01
Activation of flavin-containing oxidases underlies light-induced production of H2O2 in mammalian cells. Proc Natl Acad Sci U S A (1999) 2.00
Mitogenic properties of a calcium ionophore, A23187. Proc Natl Acad Sci U S A (1974) 1.98
The Chediak-Higashi syndrome: a possible lysosomal disease. Blood (1966) 1.94
The influence of phorbol myristate acetate on oxygen consumption by polymorphonuclear leukocytes. J Lab Clin Med (1974) 1.92
Effects of phorbol myristate acetate on the metabolism and ultrastructure of neutrophils in chronic granulomatous disease. J Clin Invest (1974) 1.92
Replication occurs at discrete foci spaced throughout nuclei replicating in vitro. J Cell Sci (1989) 1.84
Nonmuscle myosin heavy chain IIA mutations define a spectrum of autosomal dominant macrothrombocytopenias: May-Hegglin anomaly and Fechtner, Sebastian, Epstein, and Alport-like syndromes. Am J Hum Genet (2001) 1.80
Albinism and Hermansky-Pudlak syndrome in Puerto Rico. Bol Asoc Med P R (1990) 1.79
Effect of a short course of prednisone in the prevention of early relapse after the emergency room treatment of acute asthma. N Engl J Med (1991) 1.74
Influence of cytochalasin B on the shape change induced in platelets by cold. Blood (1973) 1.72
Platelet interaction with bacteria. II. Fate of the bacteria. Am J Pathol (1971) 1.71
Connectivity changes in a class of motoneurone during the development of a nematode. Nature (1978) 1.65
Uptake of latex particles by blood platelets: phagocytosis or sequestration? Am J Pathol (1972) 1.65
How the confocal laser scanning microscope entered biological research. Biol Cell (2003) 1.64
Effects of colchicine and vinca alkaloids on human platelets. 3. Influence on primary internal contraction and secondary aggregation. Am J Pathol (1969) 1.63
Effects of the lonophore A23187 on blood platelets I. Influence on aggregation and secretion. Am J Pathol (1974) 1.59
Polyploid tissues in the nematode Caenorhabditis elegans. Dev Biol (1985) 1.59
Cell fusions in the developing epithelial of C. elegans. Dev Biol (1994) 1.58
Formation of the vulva in Caenorhabditis elegans: a paradigm for organogenesis. Development (1999) 1.57
Four-dimensional imaging: the exploration of space and time. Trends Biotechnol (1998) 1.57
Metabolism and function of human platelets washed by albumin density gradient separation. Br J Haematol (1977) 1.56
Reliability of absent platelet dense bodies as a diagnostic criterion for Hermansky-Pudlak syndrome. Am J Hematol (1987) 1.56
A genetic screen for temperature-sensitive cell-division mutants of Caenorhabditis elegans. Genetics (1998) 1.55
Effects of colchicine and Vinca alkaloids on human platelets. I. Influence on platelet microtubules and contractile function. Am J Pathol (1968) 1.53
The fine structure of sickled hemoglobin in situ. Blood (1968) 1.51
Cell cycling and DNA replication in a mutant blocked in cell division in the nematode Caenorhabditis elegans. Dev Biol (1978) 1.50
The transfer of thorium particles from plasma to platelets and platelet granules. Am J Pathol (1968) 1.47
A search for the platelet secretory pathway using electron dense tracers. Am J Pathol (1970) 1.47
The C. elegans septin genes, unc-59 and unc-61, are required for normal postembryonic cytokineses and morphogenesis but have no essential function in embryogenesis. J Cell Sci (2000) 1.46
Ultrastructural studies of the gray platelet syndrome. Am J Pathol (1979) 1.45
Fibrinogen is the receptor for the endogenous lectin of human platelets. Nature (1981) 1.45
The spd-2 gene is required for polarization of the anteroposterior axis and formation of the sperm asters in the Caenorhabditis elegans zygote. Dev Biol (2000) 1.44
Wide distribution of granulophysin epitopes in granules of human tissues. Lab Invest (1993) 1.43
Production of lymphotoxin and migration inhibitory factor by established human lymphocytic cell lines. J Immunol (1970) 1.43
Separable assembly of platelet pseudopodal and contractile cytoskeletons. Cell (1982) 1.42
Localization of platelet prostaglandin production in the platelet dense tubular system. Am J Pathol (1976) 1.40
A penicillin-resistant pneumococcus. J Pediatr (1978) 1.40
Proteomic analysis of platelet alpha-granules using mass spectrometry. J Thromb Haemost (2007) 1.40
Investigation of the release reaction in platelets exposed to phorbol myristate acetate. Am J Pathol (1974) 1.39
Function of platelet mobile receptors. Thromb Haemost (1992) 1.39
A biphasic response of platelets to serotonin. Scand J Haematol (1970) 1.39
Further studies on the platelet-inhibitory effect of guanidinosuccinic acid and its role in uremic bleeding. Am J Med (1970) 1.36
Ultrastructure of clots during isometric contraction. J Cell Biol (1982) 1.35
A gene causing Hermansky-Pudlak syndrome in a Puerto Rican population maps to chromosome 10q2. Am J Hum Genet (1995) 1.35
Potentiation of complement (C5a)-induced granulocyte aggregation by cytochalasin B. J Lab Clin Med (1978) 1.33
The dense bodies of human platelets. Origin of serotonin storage particles from platelet granules. Am J Pathol (1968) 1.31
Computer reconstruction of mitochondria from yeast. Methods Enzymol (1979) 1.30
Morphogenesis of the C. elegans hermaphrodite uterus. Development (1996) 1.30
Hyperactivity of neutrophil leukotactic responses during active bacterial infection. J Clin Invest (1974) 1.29
Indirect visualization of Staphylococcus aureus protein A. J Exp Med (1970) 1.28
Defibrination syndrome in an infant born after abruptio placentae. J Pediatr (1968) 1.28
Hermansky-Pudlak syndrome type 3 in Ashkenazi Jews and other non-Puerto Rican patients with hypopigmentation and platelet storage-pool deficiency. Am J Hum Genet (2001) 1.28
Effects of the lonophore A23187 on the blood platelets II. Influence on ultrastructure. Am J Pathol (1974) 1.27
Ultrastructural features on the platelet response to phorbol myristate acetate. Am J Pathol (1974) 1.27
Membrane abnormalities of irreversibly sickled cells. Semin Hematol (1979) 1.27
Hypopigmentation in the Prader-Willi syndrome. Am J Hum Genet (1987) 1.24
Effects of colchicine and vinca alkaloids on human platelets. II. Changes in the dense tubular system and formation of an unusual inclusion in incubated cells. Am J Pathol (1968) 1.24
Effects of ethylenediamine tetracetic acid (EDTA) on platelet structure. Scand J Haematol (1968) 1.24
Autosomal recessive oculocutaneous albinism in man. Evidence for genetic heterogeneity. Am J Hum Genet (1970) 1.23