Published in Nature on May 03, 1979
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Spontaneous mutations in the CsrRS two-component regulatory system of Streptococcus pyogenes result in enhanced virulence in a murine model of skin and soft tissue infection. J Infect Dis (2001) 2.51
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Suppression of antibody and T cell proliferative responses to L-glutamic acid60-L-alanine30-L-tyrosine10 by a specific monoclonal T cell factor. J Exp Med (1980) 2.41
Disruption of hsp90 function results in degradation of the death domain kinase, receptor-interacting protein (RIP), and blockage of tumor necrosis factor-induced nuclear factor-kappaB activation. J Biol Chem (2000) 2.37
Cell wall and protoplast isoperoxidases in relation to injury, indoleacetic Acid, and ethylene effects. Plant Physiol (1974) 2.36
A randomized trial of varenicline (Chantix) for the treatment of spinocerebellar ataxia type 3. Neurology (2012) 2.34
Quasi-hexagonal molecular packing in collagen fibrils. Nature (1980) 2.28
Surgical staging in endometrial cancer: clinical-pathologic findings of a prospective study. Obstet Gynecol (1984) 2.25
Encephalitogenic T cells in the B10.PL model of experimental allergic encephalomyelitis (EAE) are of the Th-1 lymphokine subtype. Cell Immunol (1989) 2.22
A pilot trial of Cop 1 in exacerbating-remitting multiple sclerosis. N Engl J Med (1987) 2.21
The X-Y-Z scheme of immunocyte maturation. 3. Early IgM memory and the nature of the memory cell. J Immunol (1967) 2.16
Fine specificity of regulatory T cells. II. Suppressor and helper T cells are induced by different regions of hen egg-white lysozyme in a genetically nonresponder mouse strain. J Exp Med (1979) 2.12
Phonons and the elastic moduli of collagen and muscle. Nature (1977) 2.09
Cognitive-behavioral therapy to reduce weight concerns improves smoking cessation outcome in weight-concerned women. J Consult Clin Psychol (2001) 1.99
The present status of the heterogeneity of fetal hemoglobin in beta-thalassemia: an attempt to unify some observations in thalassemia and related conditions. Ann N Y Acad Sci (1974) 1.99
Determination of the elastic constants of collagen by Brillouin light scattering. J Mol Biol (1979) 1.97
Changes in pulmonary function in workers exposed to vinyl chloride and polyvinyl chloride. Ann N Y Acad Sci (1975) 1.95
Flexibility of the NSAID binding site in the structure of human cyclooxygenase-2. Nat Struct Biol (1996) 1.92
Polymorphisms in FKBP5 are associated with peritraumatic dissociation in medically injured children. Mol Psychiatry (2005) 1.91
Vascular (humoral) rejection in heart transplantation: pathologic observations and clinical implications. J Heart Transplant (1990) 1.91
Different functional specificity repertoires for suppressor and helper T cells. Immunol Rev (1978) 1.91
The asynchronous development of immunological memory in helper (T) and precursor (B) cell lines. Eur J Immunol (1971) 1.91
Mean and instantaneous expiratory flows, FVC and FEV1: prediction equations from a probability sample of Michigan, a large industrial state. Bull Eur Physiopathol Respir (1987) 1.88
The involvement of T cell receptor peptide-specific regulatory CD4+ T cells in recovery from antigen-induced autoimmune disease. J Exp Med (1993) 1.80
Monocular elevation weakness and ptosis: an oculomotor fascicular syndrome? J Clin Neuroophthalmol (1991) 1.78
Audit of emergency preoperative resuscitation. Br J Surg (1994) 1.73
Volatile compounds produced in sterile fish muscle (Sebastes melanops) by Pseudomonas perolens. Appl Microbiol (1973) 1.73
Recommendations from the National Multiple Sclerosis Society Clinical Outcomes Assessment Task Force. Ann Neurol (1997) 1.72
Structure of insect fibrillar flight muscle in the presence and absence of ATP. J Mol Biol (1972) 1.70
Analysis of the primary structure of collagen for the origins of molecular packing. J Mol Biol (1973) 1.68
Contrasting effects of glucocorticoids on the capacity of T cells to produce the growth factors interleukin 2 and interleukin 4. Eur J Immunol (1989) 1.68
Peptide-specific prevention of experimental allergic encephalomyelitis. Neonatal tolerance induced to the dominant T cell determinant of myelin basic protein. J Exp Med (1989) 1.65
A phase II study of the histone deacetylase inhibitor vorinostat combined with tamoxifen for the treatment of patients with hormone therapy-resistant breast cancer. Br J Cancer (2011) 1.65
Interpretation of the meridional X-ray diffraction pattern from collagen fibres in terms of the known amino acid sequence. J Mol Biol (1977) 1.64
Molecular conformation and packing in collagen fibrils. J Mol Biol (1983) 1.62
Epitope specificity of the T cell proliferative response to lysozyme: proliferative T cells react predominantly to different determinants from those recognized by B cells. Eur J Immunol (1980) 1.62
Mechanisms of T and B cell collaboration in the in vitro production of anti-DNA antibodies in the NZB/NZW F1 murine SLE model. J Immunol (1987) 1.60
Asbestos exposure of brake repair workers in the United States. Mt Sinai J Med (1976) 1.59
Appropriateness of medication selection for older persons in an urban academic emergency department. Acad Emerg Med (1999) 1.58
Degenerate recognition of a dissimilar antigenic peptide by myelin basic protein-reactive T cells. Implications for thymic education and autoimmunity. J Immunol (1993) 1.57
Matrix metalloproteinases and their tissue inhibitors as markers of disease subtype and response to interferon-beta therapy in relapsing and secondary-progressive multiple sclerosis patients. Ann Neurol (2001) 1.55
The Ontario Mental Health Act, 1978. A comment on its application. Can J Psychiatry (1979) 1.55
A randomised comparison of SurePath liquid-based cytology and conventional smear cytology in a colposcopy clinic setting. BJOG (2008) 1.55
Simple rule for calculating normal erythrocyte sedimentation rate. Br Med J (Clin Res Ed) (1983) 1.55
Induction of anti-self-immunity to cure cancer. Cell (1995) 1.54
Interaction of asbestos, age, and cigarette smoking in producing radiographic evidence of diffuse pulmonary fibrosis. Am J Med (1986) 1.53
The in situ supermolecular structure of type I collagen. Structure (2001) 1.50
Molecular packing in type I collagen fibrils. J Mol Biol (1987) 1.49
The closing of a social HMO: a case study. J Aging Soc Policy (1998) 1.49
A review of water quality concerns in livestock farming areas. Sci Total Environ (2000) 1.48
Neonatal T-cell tolerance to minimal immunogenic peptides is caused by clonal inactivation. Nature (1986) 1.47
T cell determinant structure: cores and determinant envelopes in three mouse major histocompatibility complex haplotypes. J Exp Med (1991) 1.47
Donor major histocompatibility complex (MHC) peptides are presented by recipient MHC molecules during graft rejection. J Exp Med (1992) 1.46
Purification and characterization of a monoclonal T-cell suppressor factor specific for poly(LGlu60LAla30LTyr10). Proc Natl Acad Sci U S A (1982) 1.46
Pulmonary diffusing capacity in left ventricular dysfunction. Chest (1990) 1.46
Diversification of T cell responses to carboxy-terminal determinants within the 65-kD heat-shock protein is involved in regulation of autoimmune arthritis. J Exp Med (1997) 1.45
Efficacy of the dorsal pedal bypass for limb salvage in diabetic patients: short-term observations. J Vasc Surg (1990) 1.45
T cell determinants from autoantibodies to DNA can upregulate autoimmunity in murine systemic lupus erythematosus. J Exp Med (1995) 1.44
Crystal structure of the extracellular region of human tissue factor. Nature (1994) 1.43
Protein disulfide isomerase and sulfhydryl-dependent pathways in platelet activation. Biochemistry (2001) 1.43
Infectious complications related to the use of the angio-seal hemostatic puncture closure device. Catheter Cardiovasc Interv (1999) 1.43
Carcinosarcoma (malignant mixed mesodermal tumor) of the uterus. A Gynecologic Oncology Group pathologic study of 203 cases. Int J Gynecol Pathol (1990) 1.42
The Bristol Bladder Tumour Registry. Br J Urol (1969) 1.42
The fine specificity of regulatory T cells. IV. Idiotypic complementarity and antigen-bridging interactions in the anti-lysozyme response. Eur J Immunol (1979) 1.42
Hepatotoxicity during treatment for multidrug-resistant tuberculosis: occurrence, management and outcome. Int J Tuberc Lung Dis (2012) 1.42
Detection-loophole-free test of quantum nonlocality, and applications. Phys Rev Lett (2013) 1.42
Melatonin as a sedation substitute for diagnostic procedures. Dev Med Child Neurol (2000) 1.41
Neonatal peptide exposure can prime T cells and, upon subsequent immunization, induce their immune deviation: implications for antibody vs. T cell-mediated autoimmunity. J Exp Med (1996) 1.40
Rapid diagnosis of massive pulmonary embolism in a district general hospital. Int J Clin Pract (2000) 1.40
Lysozyme-induced T-suppressor cells and antibodies have a predominant idiotype. Nature (1979) 1.40